PubRank

Jiahuai Han

Author PubWeight™ 192.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009 9.29
2 Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell 2005 9.01
3 Activation and signaling of the p38 MAP kinase pathway. Cell Res 2005 5.48
4 PRAK is essential for ras-induced senescence and tumor suppression. Cell 2007 4.30
5 Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol 2003 4.15
6 MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha. Science 2002 3.78
7 Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity 2007 3.38
8 Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways. Immunity 2008 2.62
9 Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway. Genes Cells 2003 2.28
10 Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell Res 2013 2.26
11 XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization. Mol Cell 2007 2.21
12 Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels. Neuron 2004 2.17
13 Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice. J Clin Invest 2008 2.15
14 p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation. Cell 2006 2.06
15 Autophagy contributes to caspase-independent macrophage cell death. J Biol Chem 2006 1.87
16 Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. J Biol Chem 2006 1.86
17 GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. Science 2012 1.84
18 Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. J Clin Invest 2009 1.80
19 Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells. Cancer Res 2006 1.80
20 Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation. EMBO J 2004 1.79
21 Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins. Immunity 2010 1.78
22 Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation. J Immunol 2008 1.68
23 Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase. J Biol Chem 2002 1.67
24 The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence. Cancer Res 2010 1.60
25 Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling. J Biol Chem 2002 1.59
26 Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1. Nat Cell Biol 2011 1.59
27 Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages. Nat Immunol 2007 1.57
28 Regulation of Nrf2 transactivation domain activity. The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein. J Biol Chem 2004 1.48
29 Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling. J Biol Chem 2013 1.48
30 Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia. EMBO J 2006 1.47
31 Inhibition of p38 MAPK by glucocorticoids via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2. J Biol Chem 2002 1.44
32 Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3. Blood 2005 1.44
33 A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell Rep 2013 1.44
34 MicroRNAs and cardiovascular diseases. FEBS J 2011 1.41
35 Calcineurin negatively regulates TLR-mediated activation pathways. J Immunol 2007 1.33
36 Distinct effects of p38alpha deletion in myeloid lineage and gut epithelia in mouse models of inflammatory bowel disease. Gastroenterology 2010 1.31
37 Regulation of PRAK subcellular location by p38 MAP kinases. Mol Biol Cell 2003 1.30
38 The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition. J Biol Chem 2002 1.29
39 TAB-1 modulates intracellular localization of p38 MAP kinase and downstream signaling. J Biol Chem 2005 1.28
40 Novel cytoplasmic proteins of nontypeable Haemophilus influenzae up-regulate human MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase-Akt pathway. J Biol Chem 2001 1.28
41 ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells. Am J Physiol Renal Physiol 2006 1.27
42 Characterization of a neurotrophin signaling mechanism that mediates neuron survival in a temporally specific pattern. J Neurosci 2003 1.27
43 Participation of the p38 pathway in Drosophila host defense against pathogenic bacteria and fungi. Proc Natl Acad Sci U S A 2010 1.27
44 Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha. J Biol Chem 2002 1.26
45 Synergistic activation of NF-kappaB by nontypeable Haemophilus influenzae and tumor necrosis factor alpha. Proc Natl Acad Sci U S A 2004 1.25
46 Multiple activation mechanisms of p38alpha mitogen-activated protein kinase. J Biol Chem 2006 1.25
47 MAPK signaling in inflammation-associated cancer development. Protein Cell 2010 1.23
48 TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1. J Biol Chem 2002 1.21
49 Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes. J Exp Med 2013 1.21
50 Cathepsin B is involved in the trafficking of TNF-alpha-containing vesicles to the plasma membrane in macrophages. J Immunol 2008 1.20
51 Multiple death pathways in TNF-treated fibroblasts: RIP3- and RIP1-dependent and independent routes. Cell Res 2011 1.20
52 p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity. J Biol Chem 2002 1.19
53 Activation of p38 alpha MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization. J Biol Chem 2002 1.19
54 p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms. J Biol Chem 2009 1.19
55 Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA(1), p42 and p38alpha. Biochim Biophys Acta 2007 1.18
56 RISC-target interaction: cleavage and translational suppression. Biochim Biophys Acta 2008 1.18
57 Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death. J Biol Chem 2004 1.18
58 A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida. Dev Cell 2007 1.16
59 Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms. J Biol Chem 2007 1.14
60 Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells. J Biol Chem 2002 1.13
61 Axin determines cell fate by controlling the p53 activation threshold after DNA damage. Nat Cell Biol 2009 1.13
62 Nod1-dependent control of tumor growth. Proc Natl Acad Sci U S A 2006 1.13
63 Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 2012 1.13
64 Orphan nuclear receptor Nur77 is involved in caspase-independent macrophage cell death. J Exp Med 2003 1.11
65 p38 MAP kinase activation mediates gamma-globin gene induction in erythroid progenitors. Exp Hematol 2003 1.11
66 Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix metalloproteinase-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways. J Biol Chem 2002 1.11
67 Essential role of p38gamma in K-Ras transformation independent of phosphorylation. J Biol Chem 2005 1.11
68 p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. J Biol Chem 2004 1.10
69 Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death. Mol Cell Biol 2003 1.10
70 Determinants of public T cell responses. Cell Res 2012 1.09
71 Inflammatory signaling and cellular senescence. Cell Signal 2008 1.08
72 Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte. Circ Res 2010 1.08
73 Receptor-interacting protein (RIP) kinase family. Cell Mol Immunol 2010 1.07
74 Differentiation state-selective roles of p38 isoforms in human intestinal epithelial cell anoikis. Gastroenterology 2002 1.07
75 Glucocorticoids synergize with IL-1beta to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells. BMC Mol Biol 2004 1.07
76 The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes. Mol Cell Biol 2008 1.06
77 Extracellular signal-regulated kinase activation mediates mitochondrial dysfunction and necrosis induced by hydrogen peroxide in renal proximal tubular cells. J Pharmacol Exp Ther 2008 1.05
78 New components of the necroptotic pathway. Protein Cell 2012 1.04
79 Recombinatorial biases and convergent recombination determine interindividual TCRβ sharing in murine thymocytes. J Immunol 2012 1.04
80 Phosphorylation of Raptor by p38beta participates in arsenite-induced mammalian target of rapamycin complex 1 (mTORC1) activation. J Biol Chem 2011 1.04
81 A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis. Mol Cell Biol 2011 1.03
82 Activation of the p38 MAP kinase pathway is required for foam cell formation from macrophages exposed to oxidized LDL. APMIS 2002 1.03
83 Determinants that control the specific interactions between TAB1 and p38alpha. Mol Cell Biol 2006 1.02
84 p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2. Cancer Res 2003 1.01
85 Mitochondrial proteins Bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death. J Biol Chem 2007 1.00
86 p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury. J Biol Chem 2005 0.99
87 Beta-actin is required for mitochondria clustering and ROS generation in TNF-induced, caspase-independent cell death. J Cell Sci 2004 0.99
88 Estrogen receptor inhibits c-Jun-dependent stress-induced cell death by binding and modifying c-Jun activity in human breast cancer cells. J Biol Chem 2003 0.98
89 Oxidative stress-induced inhibition of adrenal steroidogenesis requires participation of p38 mitogen-activated protein kinase signaling pathway. J Endocrinol 2008 0.98
90 Rin GTPase couples nerve growth factor signaling to p38 and b-Raf/ERK pathways to promote neuronal differentiation. J Biol Chem 2005 0.97
91 The role of the p38 pathway in adaptive immunity. Cell Mol Immunol 2007 0.96
92 Determinants that control the distinct subcellular localization of p38alpha-PRAK and p38beta-PRAK complexes. J Biol Chem 2008 0.95
93 Epithelial p38alpha controls immune cell recruitment in the colonic mucosa. PLoS Pathog 2010 0.95
94 AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation. Cell Metab 2013 0.95
95 Requisite role of p38 MAPK in mural cell recruitment during angiogenesis in the rat aorta model. J Vasc Res 2003 0.94
96 Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation. J Biol Chem 2003 0.94
97 COP1 and GSK3β cooperate to promote c-Jun degradation and inhibit breast cancer cell tumorigenesis. Neoplasia 2013 0.94
98 Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding. Proc Natl Acad Sci U S A 2010 0.92
99 Distinct roles of basal steady-state and induced H-ferritin in tumor necrosis factor-induced death in L929 cells. Mol Cell Biol 2005 0.91
100 Vascular smooth muscle cell proliferation requires both p38 and BMK1 MAP kinases. Arch Biochem Biophys 2002 0.91
101 The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling. EMBO Mol Med 2012 0.90
102 P38 activation mediates amyloid-beta cytotoxicity. Neurochem Res 2005 0.90
103 Identification of eight genes that are potentially involved in tamoxifen sensitivity in breast cancer cells. Cell Res 2005 0.90
104 Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways. J Biol Chem 2002 0.90
105 Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor induced apoptosis of MCF-7 cells. Mol Biol Cell 2007 0.90
106 p38γ regulates UV-induced checkpoint signaling and repair of UV-induced DNA damage. Protein Cell 2010 0.89
107 Frequency and distribution of AP-1 sites in the human genome. DNA Res 2005 0.89
108 Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis. Mol Cancer 2013 0.89
109 Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses. J Immunol 2013 0.89
110 MLK4 has negative effect on TLR4 signaling. Cell Mol Immunol 2011 0.88
111 PRAK suppresses oncogenic ras-induced hematopoietic cancer development by antagonizing the JNK pathway. Mol Cancer Res 2012 0.88
112 IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway. Am J Physiol Cell Physiol 2005 0.86
113 MyD88 beyond Toll. Nat Immunol 2006 0.86
114 Evidence that age-related changes in p38 MAP kinase contribute to the decreased steroid production by the adrenocortical cells from old rats. Aging Cell 2008 0.86
115 Dual colored mesoporous silica nanoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidity. Chem Commun (Camb) 2011 0.85
116 Helicobacter pylori VacA enhances prostaglandin E2 production through induction of cyclooxygenase 2 expression via a p38 mitogen-activated protein kinase/activating transcription factor 2 cascade in AZ-521 cells. Infect Immun 2007 0.85
117 The multifaceted effects of granulocyte colony-stimulating factor in immunomodulation and potential roles in intestinal immune homeostasis. IUBMB Life 2010 0.83
118 Mutagenesis by retroviral insertion in chemical mutagen-generated quasi-haploid mammalian cells. Biotechniques 2007 0.83
119 The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation. Sci Signal 2013 0.83
120 Efficient inhibition of HIV-1 replication by an artificial polycistronic miRNA construct. Virol J 2012 0.83
121 A potential suppressive effect of natural antisense IL-1β RNA on lipopolysaccharide-induced IL-1β expression. J Immunol 2013 0.83
122 Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins. FEBS Lett 2006 0.83
123 Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development. Blood 2002 0.81
124 The binding of actin to p38 MAPK and inhibiting its kinase activity in vitro. Sci China C Life Sci 2003 0.81
125 Retinoblastoma suppression of matrix metalloproteinase 1, but not interleukin-6, through a p38-dependent pathway in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 2004 0.81
126 Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing. Protein Cell 2010 0.81
127 The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5. J Biol Chem 2013 0.80
128 Benzothiazoline based chemodosimeters for fluorogenic detection of hypochlorous acid. Bioorg Med Chem Lett 2013 0.80
129 Regulation of GTP cyclohydrolase I gene transcription by basic region leucine zipper transcription factors. J Cell Biochem 2005 0.80
130 Nuclear protein NP60 regulates p38 MAPK activity. J Cell Sci 2005 0.79
131 AMPD3 is involved in anthrax LeTx-induced macrophage cell death. Protein Cell 2011 0.79
132 Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy. Autophagy 2012 0.79
133 Fluorogenic detection of hydrogen sulfide via reductive unmasking of o-azidomethylbenzoyl-coumarin conjugate. Chem Commun (Camb) 2012 0.79
134 Poly(styrene-alt-maleic anhydride) derivatives as potent anti-HIV microbicide candidates. Bioorg Med Chem Lett 2009 0.79
135 Quantitative phosphoproteomic analysis of RIP3-dependent protein phosphorylation in the course of TNF-induced necroptosis. Proteomics 2014 0.78
136 TNF-alpha stimulation inhibits siRNA-mediated RNA interference through a mechanism involving poly-(A) tail stabilization. Biochim Biophys Acta 2008 0.78
137 Chromo-fluorogenic detection of aldehydes with a rhodamine based sensor featuring an intramolecular deoxylactam. Org Biomol Chem 2011 0.78
138 Imaging of intracellular acidic compartments with a sensitive rhodamine based fluorogenic pH sensor. Analyst 2011 0.78
139 The P38alpha and P38delta MAP kinases may be gene therapy targets in the future treatment of severe burns. Shock 2010 0.77
140 Multivalent mannose-displaying nanoparticles constructed from poly{styrene-co-[(maleic anhydride)-alt-styrene]}. Org Biomol Chem 2009 0.77
141 Rhodamine-propargylic esters for detection of mitochondrial hydrogen sulfide in living cells. Bioorg Med Chem Lett 2013 0.76
142 A photothermal cell viability-reporting theranostic nanoprobe for intraoperative optical ablation and tracking of tumors. Chem Commun (Camb) 2014 0.75
143 Jiahuai Han: aflame on inflammation and p38. J Cell Biol 2010 0.75
144 Dietary mustard seeds (Sinapis alba Linn) suppress 1,2-dimethylhydrazine-induced immuno-imbalance and colonic carcinogenesis in rats. Nutr Cancer 2012 0.75
145 Activation of p38 and determination of its activity. Methods Mol Biol 2010 0.75
146 Resolution of lysosomes in living cells with a ratiometric molecular pH-meter. Talanta 2013 0.75
147 Optical tracking of phagocytosis with an activatable profluorophore metabolically incorporated into bacterial peptidoglycan. Anal Chem 2015 0.75
148 Corrigendum: The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells. Nat Immunol 2017 0.75
149 [Construction of a novel gene therapy lentiviral vector for drug resistant selection and detection in vivo]. Sheng Wu Gong Cheng Xue Bao 2008 0.75