Published in J Immunol on September 20, 2010
The airway epithelium in asthma. Nat Med (2012) 2.86
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation. Sci Transl Med (2014) 2.56
CB2 receptors regulate natural killer cells that limit allergic airway inflammation in a murine model of asthma. Allergy (2016) 1.39
Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection. PLoS One (2012) 1.30
Dynamic role of epithelium-derived cytokines in asthma. Clin Immunol (2012) 1.14
The microbiology of asthma. Nat Rev Microbiol (2012) 1.14
Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology. Nat Med (2012) 1.11
Natural killer cells are involved in acute lung immune injury caused by respiratory syncytial virus infection. J Virol (2011) 1.08
Cellular networks controlling Th2 polarization in allergy and immunity. F1000 Biol Rep (2012) 1.02
Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway. J Immunol (2011) 1.00
T cell-mediated host immune defenses in the lung. Annu Rev Immunol (2013) 1.00
Mechanisms of respiratory syncytial virus modulation of airway immune responses. Curr Allergy Asthma Rep (2012) 0.98
The bone marrow functions as the central site of proliferation for long-lived NK cells. J Immunol (2012) 0.97
Neonatal rhinovirus induces mucous metaplasia and airways hyperresponsiveness through IL-25 and type 2 innate lymphoid cells. J Allergy Clin Immunol (2014) 0.97
Rhinovirus-Induced Exacerbations of Asthma and COPD. Scientifica (Cairo) (2013) 0.97
Inflammatory responses to respiratory syncytial virus (RSV) infection and the development of immunomodulatory pharmacotherapeutics. Curr Med Chem (2012) 0.93
Blocking induction of T helper type 2 responses prevents development of disease in a model of childhood asthma. Clin Exp Immunol (2011) 0.92
Immunity to RSV in Early-Life. Front Immunol (2014) 0.92
Respiratory viral infection, epithelial cytokines, and innate lymphoid cells in asthma exacerbations. J Leukoc Biol (2014) 0.92
IL-17E (IL-25) and IL-17RB promote respiratory syncytial virus-induced pulmonary disease. J Leukoc Biol (2014) 0.90
Modulation of Respiratory TLR3-Anti-Viral Response by Probiotic Microorganisms: Lessons Learned from Lactobacillus rhamnosus CRL1505. Front Immunol (2014) 0.90
Clinical view on the importance of dendritic cells in asthma. Expert Rev Clin Immunol (2013) 0.84
Tissue-specific effector functions of innate lymphoid cells. Immunology (2013) 0.84
Delayed sequelae of neonatal respiratory syncytial virus infection are dependent on cells of the innate immune system. J Virol (2013) 0.83
Recent insights into pulmonary repair following virus-induced inflammation of the respiratory tract. Curr Opin Virol (2012) 0.82
Natural killer cell NKG2D and granzyme B are critical for allergic pulmonary inflammation. J Allergy Clin Immunol (2013) 0.82
Depletion of alveolar macrophages prolongs survival in response to acute pneumovirus infection. Virology (2011) 0.81
Interleukin-25 initiates Th2 differentiation of human CD4(+) T cells and influences expression of its own receptor. Immun Inflamm Dis (2015) 0.79
Responses of airway epithelium to environmental injury: role in the induction phase of childhood asthma. J Allergy (Cairo) (2011) 0.79
Role of IL-25 in Immunity. J Clin Diagn Res (2015) 0.78
Natural killer cells in asthma. Front Immunol (2013) 0.78
STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease. J Immunol (2013) 0.77
IFN-γ Blocks Development of an Asthma Phenotype in Rhinovirus-infected Baby Mice by Inhibiting ILC2s. Am J Respir Cell Mol Biol (2016) 0.75
IL-17RB(+) granulocytes are associated with airflow obstruction in asthma. Ann Allergy Asthma Immunol (2016) 0.75
Bromodomain and Extra Terminal (BET) Inhibitor Suppresses Macrophage-Driven Steroid-Resistant Exacerbations of Airway Hyper-Responsiveness and Inflammation. PLoS One (2016) 0.75
Diesel exposure suppresses natural killer cell function and resolution of eosinophil inflammation: a randomized controlled trial of exposure in allergic rhinitics. Part Fibre Toxicol (2016) 0.75
IL-25 blockade inhibits metastasis in breast cancer. Protein Cell (2016) 0.75
The Innate Cytokines IL-25, IL-33, and TSLP Cooperate in the Induction of Type 2 Innate Lymphoid Cell Expansion and Mucous Metaplasia in Rhinovirus-Infected Immature Mice. J Immunol (2017) 0.75
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol (2005) 27.17
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature (2007) 14.28
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity (2007) 13.29
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J Biol Chem (2007) 10.41
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity (2008) 10.26
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity (2008) 9.61
Bcl6 mediates the development of T follicular helper cells. Science (2009) 8.50
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity (2009) 6.87
Regulation of inflammatory responses by IL-17F. J Exp Med (2008) 5.56
T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity (2009) 4.69
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat Med (2011) 4.50
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest (2003) 4.08
Eosinophils: biological properties and role in health and disease. Clin Exp Allergy (2008) 3.92
Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med (2007) 3.91
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nat Immunol (2006) 3.76
IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med (2007) 3.66
CCR6 regulates the migration of inflammatory and regulatory T cells. J Immunol (2008) 3.51
Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells. Eur J Immunol (2009) 3.42
Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes. Cell Res (2006) 3.41
ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity. J Exp Med (2008) 3.39
B7S1, a novel B7 family member that negatively regulates T cell activation. Immunity (2003) 3.18
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest (2003) 3.16
Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor. J Biol Chem (2006) 3.16
Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation. J Biol Chem (2007) 3.14
Toll-like receptor 2 signaling in CD4(+) T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease. Immunity (2010) 2.90
Characterization of mouse and human B7-H3 genes. J Immunol (2002) 2.86
Eosinophils: changing perspectives in health and disease. Nat Rev Immunol (2012) 2.69
Transcriptional regulation of th2 differentiation by inducible costimulator. Immunity (2003) 2.56
A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses. Cell Res (2007) 2.50
A critical role of neural-specific JNK3 for ischemic apoptosis. Proc Natl Acad Sci U S A (2003) 2.47
Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E. Immunity (2011) 2.39
Murine B7-H3 is a negative regulator of T cells. J Immunol (2004) 2.33
TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease. J Exp Med (2008) 2.33
Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease. Proc Natl Acad Sci U S A (2009) 2.28
Eosinophil trafficking in allergy and asthma. J Allergy Clin Immunol (2007) 2.27
Cyclic alternating pattern in sleep and its relationship to creativity. Sleep Med (2011) 2.21
IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity. J Exp Med (2008) 2.19
Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun (2009) 2.19
Effects of anticytokine therapy in a mouse model of chronic asthma. Am J Respir Crit Care Med (2004) 2.15
Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis. J Immunol (2006) 2.15
Limbal relaxing incisions versus on-axis incisions to reduce corneal astigmatism at the time of cataract surgery. J Cataract Refract Surg (2005) 2.12
Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. Genes Dev (2003) 2.10
Chemokines in asthma: cooperative interaction between chemokines and IL-13. J Allergy Clin Immunol (2003) 2.06
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma. J Exp Med (2002) 2.04
Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5. Nature (2004) 1.99
Retracted Inducible costimulator is essential for collagen-induced arthritis. J Clin Invest (2003) 1.94
T-cell tolerance or function is determined by combinatorial costimulatory signals. EMBO J (2006) 1.92
Regulation of IL-9 expression by IL-25 signaling. Nat Immunol (2010) 1.78
IL-17 family member cytokines: regulation and function in innate immunity. Cytokine Growth Factor Rev (2010) 1.76
B7-H3 is a potent inhibitor of human T-cell activation: No evidence for B7-H3 and TREML2 interaction. Eur J Immunol (2009) 1.71
Bcl6 expression specifies the T follicular helper cell program in vivo. J Exp Med (2012) 1.69
Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice. J Allergy Clin Immunol (2013) 1.67
Ym1/2 promotes Th2 cytokine expression by inhibiting 12/15(S)-lipoxygenase: identification of a novel pathway for regulating allergic inflammation. J Immunol (2009) 1.67
Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology. J Allergy Clin Immunol (2010) 1.66
Signaling of interleukin-17 family cytokines in immunity and inflammation. Cell Signal (2010) 1.66
Regulation and function of proinflammatory TH17 cells. Ann N Y Acad Sci (2008) 1.65
Long-term endoscopic management of upper tract urothelial carcinoma: 20-year single-centre experience. BJU Int (2012) 1.64
Immunopathogenesis of experimental ulcerative colitis is mediated by eosinophil peroxidase. J Immunol (2004) 1.62
IL-17F: regulation, signaling and function in inflammation. Cytokine (2009) 1.56
Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts. J Immunol (2009) 1.54
Cigarette smoke induction of osteopontin (SPP1) mediates T(H)17 inflammation in human and experimental emphysema. Sci Transl Med (2012) 1.54
Eosinophils contribute to innate antiviral immunity and promote clearance of respiratory syncytial virus. Blood (2007) 1.52
Endoscopic versus laparoscopic management of noninvasive upper tract urothelial carcinoma: 20-year single center experience. J Urol (2012) 1.52
Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis. EMBO Rep (2002) 1.52
STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J Biol Chem (2012) 1.51
Cutting Edge: Programmed death (PD) ligand-1/PD-1 interaction is required for CD8+ T cell tolerance to tissue antigens. J Immunol (2006) 1.49
Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses. Am J Respir Crit Care Med (2009) 1.47
Modeling allergic asthma in mice: pitfalls and opportunities. Am J Respir Cell Mol Biol (2002) 1.47
Regulation of microRNA by antagomirs: a new class of pharmacological antagonists for the specific regulation of gene function? Am J Respir Cell Mol Biol (2006) 1.47
Regulation of T cell activation and tolerance by PDL2. Proc Natl Acad Sci U S A (2006) 1.46
BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation. J Immunol (2006) 1.45
CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation. Genes Dev (2007) 1.45
A role for eosinophils in airway remodelling in asthma. Trends Immunol (2004) 1.44
Inhibition of house dust mite-induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment. J Allergy Clin Immunol (2011) 1.44
Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t protein. J Biol Chem (2011) 1.43
The "classical" ovalbumin challenge model of asthma in mice. Curr Drug Targets (2008) 1.42
Schistosoma mansoni infection in eosinophil lineage-ablated mice. Blood (2006) 1.42
Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness. J Immunol (2006) 1.40
Yin-Yang of costimulation: crucial controls of immune tolerance and function. Immunol Rev (2009) 1.39
Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation. J Biol Chem (2009) 1.38
Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease. Immunity (2011) 1.38
The IL-17/IL-23 axis of inflammation in cancer: friend or foe? Curr Opin Investig Drugs (2009) 1.36
T helper 17 cells play a critical pathogenic role in lung cancer. Proc Natl Acad Sci U S A (2014) 1.36
Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease. Nat Med (2007) 1.36
Regulation of carcinogenesis by IL-5 and CCL11: a potential role for eosinophils in tumor immune surveillance. J Immunol (2007) 1.36
MAP kinases in immune responses. Cell Mol Immunol (2005) 1.34
Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation. Proc Natl Acad Sci U S A (2012) 1.32
B7h is required for T cell activation, differentiation, and effector function. Proc Natl Acad Sci U S A (2003) 1.32
The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation. Immunity (2010) 1.31
Repression of photosynthesis gene expression by formation of a disulfide bond in CrtJ. Proc Natl Acad Sci U S A (2002) 1.31
Transcriptional regulation of follicular T-helper (Tfh) cells. Immunol Rev (2013) 1.28
The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. Nat Immunol (2013) 1.26
Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice. Am J Respir Crit Care Med (2003) 1.25