New class of potent antitumor acylhydrazone derivatives containing furan.

PubWeight™: 1.82‹?› | Rank: Top 3%

🔗 View Article (PMID 20884091)

Published in Eur J Med Chem on September 17, 2010

Authors

Zining Cui1, Ying Li, Yun Ling, Juan Huang, Jingrong Cui, Ruiqing Wang, Xinling Yang

Author Affiliations

1: Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, People's Republic of China.

Articles citing this

(E)-1-(2,4-Dinitro-phen-yl)-2-[1-(2-meth-oxy-phen-yl)ethyl-idene]hydrazine. Acta Crystallogr Sect E Struct Rep Online (2011) 1.36

(E)-1-[1-(3-Chloro-phen-yl)ethyl-idene]-2-(2,4-dinitro-phen-yl)hydrazine. Acta Crystallogr Sect E Struct Rep Online (2012) 0.95

(E)-1-(2,4-Dinitro-phen-yl)-2-[1-(4-fluoro-phen-yl)ethyl-idene]hydrazine. Acta Crystallogr Sect E Struct Rep Online (2012) 0.94

1-(2,4-Di-nitro-phen-yl)-2-[(E)-2,4,5-tri-meth-oxy-benzyl-idene]hydrazine. Acta Crystallogr Sect E Struct Rep Online (2013) 0.90

(E)-1-(2,4-Dinitro-phen-yl)-2-[1-(3-fluoro-phen-yl)ethyl-idene]hydrazine. Acta Crystallogr Sect E Struct Rep Online (2012) 0.85

Synthesis and fungicidal activity of novel 2,5-disubstituted-1,3,4- thiadiazole derivatives containing 5-phenyl-2-furan. Sci Rep (2016) 0.83

Molecular design and synthesis of novel salicyl glycoconjugates as elicitors against plant diseases. PLoS One (2014) 0.81

Design, synthesis and bioactivity of N-glycosyl-N'-(5-substituted phenyl-2-furoyl) hydrazide derivatives. Int J Mol Sci (2014) 0.79

Synthesis and bioactivity of 5-substituted-2-furoyl diacylhydazide derivatives with aliphatic chain. Int J Mol Sci (2014) 0.79

Lead optimization of an acylhydrazone scaffold possessing antiviral activity against Lassa virus. Bioorg Med Chem Lett (2013) 0.78

A review exploring biological activities of hydrazones. J Pharm Bioallied Sci (2014) 0.78

1-(2,4-Di-nitro-phen-yl)-2-[(E)-(3,4,5-tri-meth-oxy-benzyl-idene)]hydrazine. Acta Crystallogr Sect E Struct Rep Online (2014) 0.75

Synthesis of furo[3,2-b]pyrrole-5-carboxhydrazides and their Cu, Co and Ni complexes. ScientificWorldJournal (2012) 0.75

(E)-1-(2,4-Dinitro-phen-yl)-2-[1-(3-nitro-phen-yl)ethyl-idene]hydrazine. Acta Crystallogr Sect E Struct Rep Online (2012) 0.75

Synthesis, characterization and antitumor activity of Ln(III) complexes with hydrazone Schiff base derived from 2-acetylpyridine and isonicotinohydrazone. Oncol Lett (2017) 0.75

Articles by these authors

(truncated to the top 100)

The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19

Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease. J Am Soc Nephrol (2006) 8.05

Genome sequence and analysis of the tuber crop potato. Nature (2011) 7.77

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity (2008) 7.60

Negative Staining and Image Classification - Powerful Tools in Modern Electron Microscopy. Biol Proced Online (2004) 6.14

Fate mapping of IL-17-producing T cells in inflammatory responses. Nat Immunol (2011) 5.98

Incorporating structure to predict microRNA targets. Proc Natl Acad Sci U S A (2005) 5.68

DNA helicase Srs2 disrupts the Rad51 presynaptic filament. Nature (2003) 5.66

Validation of the ITS2 region as a novel DNA barcode for identifying medicinal plant species. PLoS One (2010) 5.39

Aptamers evolved from live cells as effective molecular probes for cancer study. Proc Natl Acad Sci U S A (2006) 5.35

Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell (2005) 5.10

Mitochondrial gene replacement in primate offspring and embryonic stem cells. Nature (2009) 4.98

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci U S A (2010) 4.95

Sequence and analysis of rice chromosome 4. Nature (2002) 4.39

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells. J Immunol (2007) 3.47

Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars. Nat Genet (2013) 3.41

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature (2012) 3.38

Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist. Science (2006) 3.26

The Selaginella genome identifies genetic changes associated with the evolution of vascular plants. Science (2011) 3.10

Use of ITS2 region as the universal DNA barcode for plants and animals. PLoS One (2010) 2.92

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat Neurosci (2013) 2.71

Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13. Cell (2011) 2.58

Selection of aptamers for molecular recognition and characterization of cancer cells. Anal Chem (2007) 2.57

Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J Proteome Res (2008) 2.44

The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A (2010) 2.43

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J Exp Med (2009) 2.41

De novo sequencing and analysis of the American ginseng root transcriptome using a GS FLX Titanium platform to discover putative genes involved in ginsenoside biosynthesis. BMC Genomics (2010) 2.41

The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. Immunity (2009) 2.21

The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila. Development (2005) 2.19

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet (2012) 2.17

Barriers to accessing TB diagnosis for rural-to-urban migrants with chronic cough in Chongqing, China: a mixed methods study. BMC Health Serv Res (2008) 2.17

Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks. Nat Genet (2010) 2.16

Hyperphosphorylation of the cardiac ryanodine receptor at serine 2808 is not involved in cardiac dysfunction after myocardial infarction. Circ Res (2012) 2.16

Actin homolog MreBH governs cell morphogenesis by localization of the cell wall hydrolase LytE. Dev Cell (2006) 2.14

Long-term calcium supplementation may have adverse effects on serum cholesterol and carotid intima-media thickness in postmenopausal women: a double-blind, randomized, placebo-controlled trial. Am J Clin Nutr (2013) 2.11

Functional regeneration of supraspinal connections in a patient with transected spinal cord following transplantation of bulbar olfactory ensheathing cells with peripheral nerve bridging. Cell Transplant (2014) 2.09

Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis. J Cell Biol (2007) 2.07

Multitarget therapy for induction treatment of lupus nephritis: a randomized trial. Ann Intern Med (2015) 1.99

Utility of N-terminal pro B-type natriuretic peptide and mean platelet volume in differentiating congestive heart failure from chronic obstructive pulmonary disease. Int J Cardiol (2013) 1.99

The crystal structure of the bifunctional primase-helicase of bacteriophage T7. Mol Cell (2003) 1.99

Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro. Biol Reprod (2007) 1.94

Identification of liver cancer-specific aptamers using whole live cells. Anal Chem (2008) 1.90

Expression of stimulated by retinoic acid gene 8 (Stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes. Biol Reprod (2008) 1.89

Reduction of RF-induced sample heating with a scroll coil resonator structure for solid-state NMR probes. J Magn Reson (2005) 1.89

Autophagy contributes to leaf starch degradation. Plant Cell (2013) 1.85

Serotonin regulates rhythmic whisking. Neuron (2003) 1.83

Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy. Circ Arrhythm Electrophysiol (2008) 1.77

Estimation of 10-year risk of fatal and nonfatal ischemic cardiovascular diseases in Chinese adults. Circulation (2006) 1.73

Structural basis of glaucoma: the fortified astrocytes of the optic nerve head are the target of raised intraocular pressure. Glia (2011) 1.73

Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nat Biotechnol (2010) 1.71

SIRT1 is essential for normal cognitive function and synaptic plasticity. J Neurosci (2010) 1.71

Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples. Clin Chem (2007) 1.69

Expression of human apoAII in transgenic rabbits leads to dyslipidemia: a new model for combined hyperlipidemia. Arterioscler Thromb Vasc Biol (2009) 1.64

Dysfunctional transforming growth factor-β signaling with constitutively active Notch signaling in Barrett's esophageal adenocarcinoma. Cancer (2011) 1.63

Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression. Hepatology (2009) 1.62

Authentication of the family Polygonaceae in Chinese pharmacopoeia by DNA barcoding technique. J Ethnopharmacol (2009) 1.62

Relative peripheral hyperopic defocus alters central refractive development in infant monkeys. Vision Res (2009) 1.61

Role of ADAM17 in the ectodomain shedding of TNF-alpha and its receptors by neutrophils and macrophages. J Leukoc Biol (2007) 1.61

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice. Hepatology (2014) 1.60

Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation. Nat Cell Biol (2012) 1.60

The whisking rhythm generator: a novel mammalian network for the generation of movement. J Neurophysiol (2007) 1.58

Protective effects of high ambient lighting on the development of form-deprivation myopia in rhesus monkeys. Invest Ophthalmol Vis Sci (2012) 1.58

Restoration of hand function in a rat model of repair of brachial plexus injury. Brain (2009) 1.57

Effect of modulating unfolded state structure on the folding kinetics of the villin headpiece subdomain. Proc Natl Acad Sci U S A (2005) 1.55

Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with review of the relevant published work. J Dermatol (2010) 1.54

Effects of chromogranin A deficiency and excess in vivo: biphasic blood pressure and catecholamine responses. J Hypertens (2010) 1.54

Protective immunization against inhalational anthrax: a comparison of minimally invasive delivery platforms. J Infect Dis (2004) 1.53

Simultaneous quantification of jasmonic acid and salicylic acid in plants by vapor-phase extraction and gas chromatography-chemical ionization-mass spectrometry. Anal Biochem (2003) 1.53

Ten SNPs of PAX6, Lumican, and MYOC genes are not associated with high myopia in Han Chinese. Ophthalmic Genet (2012) 1.50

The antiemetic 5-HT3 receptor antagonist Palonosetron inhibits substance P-mediated responses in vitro and in vivo. J Pharmacol Exp Ther (2010) 1.48

A decreased mean platelet volume is associated with stable and exacerbated asthma. Respiration (2014) 1.48

Factors affecting operational tolerance after pediatric living-donor liver transplantation: impact of early post-transplant events and HLA match. Transpl Int (2011) 1.48

Decreased serum bilirubin is associated with silent cerebral infarction. Arterioscler Thromb Vasc Biol (2013) 1.47

Hepatitis B virus reactivation in patients with multiple myeloma receiving bortezomib-containing regimens followed by autologous stem cell transplant. Leuk Lymphoma (2015) 1.47

Fasting serum lipid and dehydroepiandrosterone sulfate as important metabolites for detecting isolated postchallenge diabetes: serum metabolomics via ultra-high-performance LC-MS. Clin Chem (2013) 1.46

High-throughput sequence determination of cyclic peptide library members by partial Edman degradation/mass spectrometry. J Am Chem Soc (2006) 1.45

Evidence based acupuncture practice recommendations for peripheral facial paralysis. Am J Chin Med (2009) 1.45

Baseline pulmonary function and quality of life 9 years later in a middle-aged Chinese population. Chest (2005) 1.45

Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation. PLoS One (2010) 1.45

Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4. Biochemistry (2007) 1.44

Role of ATP hydrolysis in the antirecombinase function of Saccharomyces cerevisiae Srs2 protein. J Biol Chem (2004) 1.43

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma. Cancer Res (2013) 1.43

Arabidopsis sigma factor binding proteins are activators of the WRKY33 transcription factor in plant defense. Plant Cell (2011) 1.43

Identification of Dendrobium species by a candidate DNA barcode sequence: the chloroplast psbA-trnH intergenic region. Planta Med (2009) 1.42

Construction of reference chromosome-scale pseudomolecules for potato: integrating the potato genome with genetic and physical maps. G3 (Bethesda) (2013) 1.42

Systemically delivered insulin-like growth factor-I enhances mesenchymal stem cell-dependent fracture healing. Growth Factors (2012) 1.42

Detection of glaucoma progression by population and individual derived variability criteria. Br J Ophthalmol (2012) 1.40

Impact of inborn errors of metabolism on admission in a neonatal intensive care unit--a prospective cohort study. Indian J Pediatr (2011) 1.40

Microwave and optical saturable absorption in graphene. Opt Express (2012) 1.40

Structure of the catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor. Biochemistry (2006) 1.39

Application of attitude jitter detection based on short-time asynchronous images and compensation methods for Chinese mapping satellite-1. Opt Express (2015) 1.39

Rac1 is required for cardiomyocyte apoptosis during hyperglycemia. Diabetes (2009) 1.38

Subtype distribution of lymphomas in Southwest China: analysis of 6,382 cases using WHO classification in a single institution. Diagn Pathol (2011) 1.38

Control of life-or-death decisions by RIP1 kinase. Annu Rev Physiol (2013) 1.37

Utilization of Fc receptors as a mucosal vaccine strategy against an intracellular bacterium, Francisella tularensis. J Immunol (2008) 1.36

3-[(E)-3,7-Dimethyl-octa-2,6-dien-yl]-5-methyl-N-nitro-1,3,5-oxadiazinan-4-imine. Acta Crystallogr Sect E Struct Rep Online (2008) 1.35

BMI is strongly associated with hypertension, and waist circumference is strongly associated with type 2 diabetes and dyslipidemia, in northern Chinese adults. J Epidemiol (2012) 1.35

Effects of foveal ablation on emmetropization and form-deprivation myopia. Invest Ophthalmol Vis Sci (2007) 1.35

Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation. Int Immunol (2011) 1.35

Hominoid-specific de novo protein-coding genes originating from long non-coding RNAs. PLoS Genet (2012) 1.35