Published in Nat Chem Biol on December 15, 2011
The microbiome and cancer. Nat Rev Cancer (2013) 2.86
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response. Nature (2012) 1.99
Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node. Immunity (2013) 1.65
Type I interferons link viral infection to enhanced epithelial turnover and repair. Cell Host Microbe (2014) 1.53
Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4. Immunity (2014) 1.28
Secretory IgA: Designed for Anti-Microbial Defense. Front Immunol (2013) 1.27
Dynamic distribution of the gut microbiota and the relationship with apparent crude fiber digestibility and growth stages in pigs. Sci Rep (2015) 1.14
Phosphoinositide-mediated oligomerization of a defensin induces cell lysis. Elife (2014) 1.11
Trial Watch: Immunogenic cell death inducers for anticancer chemotherapy. Oncoimmunology (2015) 1.07
Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ. PLoS Pathog (2014) 1.03
Gastrointestinal function development and microbiota. Ital J Pediatr (2013) 0.98
Arginine consumption by the intestinal parasite Giardia intestinalis reduces proliferation of intestinal epithelial cells. PLoS One (2012) 0.95
Shigella IpaH0722 E3 ubiquitin ligase effector targets TRAF2 to inhibit PKC-NF-κB activity in invaded epithelial cells. PLoS Pathog (2013) 0.95
BopA does not have a major role in the adhesion of Bifidobacterium bifidum to intestinal epithelial cells, extracellular matrix proteins, and mucus. Appl Environ Microbiol (2013) 0.92
CD4+ T cells drive goblet cell depletion during Citrobacter rodentium infection. Infect Immun (2013) 0.91
Spatial segregation of virulence gene expression during acute enteric infection with Salmonella enterica serovar Typhimurium. MBio (2014) 0.90
Systems-level overview of host protein phosphorylation during Shigella flexneri infection revealed by phosphoproteomics. Mol Cell Proteomics (2013) 0.89
Interactions between Nod-Like Receptors and Intestinal Bacteria. Front Immunol (2013) 0.89
Gut Microbiota and Celiac Disease. Dig Dis Sci (2016) 0.87
Mucosal Inflammatory Response to Salmonella typhimurium Infection. Front Immunol (2014) 0.87
Dietary Factors: Major Regulators of the Gut's Microbiota. Gut Liver (2012) 0.86
Electrolyte transport pathways induced in the midgut epithelium of Drosophila melanogaster larvae by commensal gut microbiota and pathogens. J Physiol (2016) 0.86
Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages. Proc Natl Acad Sci U S A (2014) 0.86
Vibrio vulnificus VvhA induces NF-κB-dependent mitochondrial cell death via lipid raft-mediated ROS production in intestinal epithelial cells. Cell Death Dis (2015) 0.86
What does irritable bowel syndrome share with non-alcoholic fatty liver disease? World J Gastroenterol (2013) 0.85
Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers. EMBO Mol Med (2012) 0.85
Structure of an SspH1-PKN1 complex reveals the basis for host substrate recognition and mechanism of activation for a bacterial E3 ubiquitin ligase. Mol Cell Biol (2013) 0.85
Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases. Am J Physiol Gastrointest Liver Physiol (2014) 0.84
Perinatal nutrition programs neuroimmune function long-term: mechanisms and implications. Front Neurosci (2013) 0.82
Bacterial colonization and intestinal mucosal barrier development. World J Clin Pediatr (2013) 0.81
Disruptions of Host Immunity and Inflammation by Giardia Duodenalis: Potential Consequences for Co-Infections in the Gastro-Intestinal Tract. Pathogens (2015) 0.80
The Gdac1 locus modifies spontaneous and Salmonella-induced colitis in mice deficient in either Gpx2 or Gpx1 gene. Free Radic Biol Med (2013) 0.80
Intestinal microbiota succession and immunomodulatory consequences after introduction of Lactobacillus reuteri I5007 in neonatal piglets. PLoS One (2015) 0.79
Serum Endotoxins and Flagellin and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort. Cancer Epidemiol Biomarkers Prev (2016) 0.78
Extinction, coexistence, and localized patterns of a bacterial population with contact-dependent inhibition. BMC Syst Biol (2014) 0.78
Shigella flexneri Inhibits Intestinal Inflammation by Modulation of Host Sphingosine-1-Phosphate in Mice. Immune Netw (2014) 0.77
Transport of particles in intestinal mucus under simulated infant and adult physiological conditions: impact of mucus structure and extracellular DNA. PLoS One (2014) 0.77
Dietary Mannan Oligosaccharides: Counteracting the Side Effects of Soybean Meal Oil Inclusion on European Sea Bass (Dicentrarchus labrax) Gut Health and Skin Mucosa Mucus Production? Front Immunol (2015) 0.76
Interleukin-8, CXCL1, and MicroRNA miR-146a Responses to Probiotic Escherichia coli Nissle 1917 and Enteropathogenic E. coli in Human Intestinal Epithelial T84 and Monocytic THP-1 Cells after Apical or Basolateral Infection. Infect Immun (2016) 0.75
Characterization of faecal microbial communities of dairy cows fed diets containing ensiled Moringa oleifera fodder. Sci Rep (2017) 0.75
Paraoxonase 2 modulates a proapoptotic function in LS174T cells in response to quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone. Sci Rep (2016) 0.75
Loss of culturability of Salmonella enterica subsp. enterica serovar Typhimurium upon cell-cell contact with human fecal bacteria. Appl Environ Microbiol (2013) 0.75
Microbiology and ecology are vitally important to premedical curricula. Evol Med Public Health (2015) 0.75
Clustered Intracellular Salmonella enterica Serovar Typhimurium Blocks Host Cell Cytokinesis. Infect Immun (2016) 0.75
Norepinephrine potentiates proinflammatory responses of human vaginal epithelial cells. J Neuroimmunol (2013) 0.75
Bacterial Signaling to the Nervous System via Toxins and Metabolites. J Mol Biol (2017) 0.75
Bacteriophage infections of microbiota can lead to leaky gut in an experimental rodent model. Gut Pathog (2016) 0.75
Influence of ad Libitum Feeding of Piglets With Bacillus Subtilis Fermented Liquid Feed on Gut Flora, Luminal Contents and Health. Sci Rep (2017) 0.75
Intestinal Barrier Disturbances in Haemodialysis Patients: Mechanisms, Consequences, and Therapeutic Options. Biomed Res Int (2017) 0.75
Development of putative probiotics as feed additives: validation in a porcine-specific gastrointestinal tract model. Appl Microbiol Biotechnol (2016) 0.75
Effects of different diets on intestinal microbiota and nonalcoholic fatty liver disease development. World J Gastroenterol (2016) 0.75
Heterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections. Front Cell Infect Microbiol (2017) 0.75
Petri Net-Based Model of Helicobacter pylori Mediated Disruption of Tight Junction Proteins in Stomach Lining during Gastric Carcinoma. Front Microbiol (2017) 0.75
Immune balance: the development of the idea and its applications. J Hist Biol (2014) 0.75
Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway. PLoS One (2017) 0.75
Gut Dysbiosis in Animals Due to Environmental Chemical Exposures. Front Cell Infect Microbiol (2017) 0.75
Bacteriophages as potential new mammalian pathogens. Sci Rep (2017) 0.75
Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell (2009) 20.29
Induction of colonic regulatory T cells by indigenous Clostridium species. Science (2010) 16.71
Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell (1996) 14.75
Antibacterial resistance worldwide: causes, challenges and responses. Nat Med (2004) 10.46
The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses. Immunity (2009) 8.95
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature (2009) 8.71
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol (2007) 7.58
Protein delivery into eukaryotic cells by type III secretion machines. Nature (2006) 7.49
Intestinal mucosal barrier function in health and disease. Nat Rev Immunol (2009) 7.15
Gut inflammation provides a respiratory electron acceptor for Salmonella. Nature (2010) 6.25
Bifidobacteria can protect from enteropathogenic infection through production of acetate. Nature (2011) 5.83
Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat Rev Immunol (2010) 5.57
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe (2007) 5.56
Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science (2003) 5.23
Mucin dynamics and enteric pathogens. Nat Rev Microbiol (2011) 4.23
Molecular mechanisms of Escherichia coli pathogenicity. Nat Rev Microbiol (2010) 4.13
Identification of a bacterial type III effector family with G protein mimicry functions. Cell (2006) 3.47
AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling. Science (2008) 3.44
Tissue damage-induced intestinal stem cell division in Drosophila. Cell Stem Cell (2009) 3.43
Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. Am J Pathol (2005) 3.22
Modulation of Shigella virulence in response to available oxygen in vivo. Nature (2010) 2.96
MUC1 cell surface mucin is a critical element of the mucosal barrier to infection. J Clin Invest (2007) 2.90
TLR signaling is required for Salmonella typhimurium virulence. Cell (2011) 2.88
Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota. Infect Immun (2007) 2.80
Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli. Infect Immun (1999) 2.78
Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa. Trends Microbiol (2004) 2.66
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity. Nature (2007) 2.48
Shifting the balance: antibiotic effects on host-microbiota mutualism. Nat Rev Microbiol (2011) 2.43
Helicobacter pylori dampens gut epithelial self-renewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach. Cell Host Microbe (2007) 2.41
Salmonella takes control: effector-driven manipulation of the host. Curr Opin Microbiol (2009) 2.41
Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells. Cell Host Microbe (2009) 2.21
Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells. Nat Med (2002) 2.20
pH sensing by intracellular Salmonella induces effector translocation. Science (2010) 2.13
Small-molecule inhibitors specifically targeting type III secretion. Infect Immun (2005) 2.02
Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells. Proc Natl Acad Sci U S A (1998) 1.96
Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin. J Clin Invest (1998) 1.89
Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells. Proc Natl Acad Sci U S A (2005) 1.89
Mechanisms controlling pathogen colonization of the gut. Curr Opin Microbiol (2010) 1.88
Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. J Immunol (2008) 1.83
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. Science (2010) 1.77
Enteropathogenic Escherichia coli EspF is targeted to mitochondria and is required to initiate the mitochondrial death pathway. Cell Microbiol (2004) 1.76
Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic. Proc Natl Acad Sci U S A (2006) 1.75
The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt. J Biol Chem (2005) 1.74
The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation. Cell Host Microbe (2009) 1.74
Salmonella Typhimurium type III secretion effectors stimulate innate immune responses in cultured epithelial cells. PLoS Pathog (2009) 1.73
MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy. PLoS Pathog (2009) 1.69
Cell death and infection: a double-edged sword for host and pathogen survival. J Cell Biol (2011) 1.69
Salmonella AvrA Coordinates Suppression of Host Immune and Apoptotic Defenses via JNK Pathway Blockade. Cell Host Microbe (2008) 1.69
Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter. J Biol Chem (2006) 1.59
Perturbation of the small intestine microbial ecology by streptomycin alters pathology in a Salmonella enterica serovar typhimurium murine model of infection. Infect Immun (2009) 1.59
Targeting of enteropathogenic Escherichia coli EspF to host mitochondria is essential for bacterial pathogenesis: critical role of the 16th leucine residue in EspF. J Biol Chem (2004) 1.57
The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. Gastroenterology (2011) 1.54
A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling. Cell (2007) 1.51
Bacterial interactions with the host epithelium. Cell Host Microbe (2010) 1.48
Tight junctions as targets of infectious agents. Biochim Biophys Acta (2008) 1.47
Role of intestinal mucins in innate host defense mechanisms against pathogens. J Innate Immun (2008) 1.45
Muc1 mucin limits both Helicobacter pylori colonization of the murine gastric mucosa and associated gastritis. Gastroenterology (2007) 1.43
Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium. Antimicrob Agents Chemother (2007) 1.43
NleH effectors interact with Bax inhibitor-1 to block apoptosis during enteropathogenic Escherichia coli infection. Proc Natl Acad Sci U S A (2010) 1.43
Helicobacter pylori dysregulation of gastric epithelial tight junctions by urease-mediated myosin II activation. Gastroenterology (2008) 1.41
The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells. Infect Immun (2005) 1.40
Haemagglutinin/protease expression and mucin gel penetration in El Tor biotype Vibrio cholerae. Microbiology (2003) 1.38
Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets. BMC Genomics (2007) 1.35
Salmonella enterica serovar Typhimurium effectors SopB, SopE, SopE2 and SipA disrupt tight junction structure and function. Cell Microbiol (2006) 1.34
From the gut to the peripheral tissues: the multiple effects of butyrate. Nutr Res Rev (2010) 1.32
Warner-Lambert/Parke-Davis Award lecture. Pathobiology of the intestinal epithelial barrier. Am J Pathol (1990) 1.30
Molecular mechanisms of epithelial-barrier disruption by Helicobacter pylori. Trends Microbiol (2008) 1.30
A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle. Proc Natl Acad Sci U S A (2009) 1.29
Selective inhibition of type III secretion activated signaling by the Salmonella effector AvrA. PLoS Pathog (2009) 1.29
Small-molecule type III secretion system inhibitors block assembly of the Shigella type III secreton. J Bacteriol (2008) 1.24
Pathogenic bacteria target NEDD8-conjugated cullins to hijack host-cell signaling pathways. PLoS Pathog (2010) 1.23
Transit time of epithelial cells in the small intestines of germfree mice and ex-germfree mice associated with indigenous microorganisms. Appl Environ Microbiol (1981) 1.23
Genes in the Salmonella pathogenicity island 2 and the Salmonella virulence plasmid are essential for Salmonella-induced apoptosis in intestinal epithelial cells. Cell Microbiol (2002) 1.22
Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins. Biochim Biophys Acta (2009) 1.22
Campylobacter jejuni response to human mucin MUC2: modulation of colonization and pathogenicity determinants. J Med Microbiol (2008) 1.19
Formate acts as a diffusible signal to induce Salmonella invasion. J Bacteriol (2008) 1.18
Bacterial cyclomodulin Cif blocks the host cell cycle by stabilizing the cyclin-dependent kinase inhibitors p21 and p27. Cell Microbiol (2008) 1.18
Subversion of actin dynamics by EspM effectors of attaching and effacing bacterial pathogens. Cell Microbiol (2008) 1.14
Virulence mechanisms and persistence strategies of the human gastric pathogen Helicobacter pylori. Curr Top Microbiol Immunol (2009) 1.14
The bacterial virulence factor NleA is required for the disruption of intestinal tight junctions by enteropathogenic Escherichia coli. Cell Microbiol (2009) 1.14
TNF-induced enterocyte apoptosis and detachment in mice: induction of caspases and prevention by a caspase inhibitor, ZVAD-fmk. Lab Invest (1999) 1.12
Enteropathogenic Escherichia coli effector EspF interacts with host protein Abcf2. Cell Microbiol (2006) 1.10
Enteric pathogen exploitation of the microbiota-generated nutrient environment of the gut. Curr Opin Microbiol (2011) 1.09
Targeting virulence for antibacterial chemotherapy: identifying and characterising virulence factors for lead discovery. Drugs R D (2006) 1.09
Mechanisms of epithelial cell shedding in the Mammalian intestine and maintenance of barrier function. Ann N Y Acad Sci (2009) 1.06
The bacterial effector Cif interferes with SCF ubiquitin ligase function by inhibiting deneddylation of Cullin1. Biochem Biophys Res Commun (2010) 1.02
Homeostasis in infected epithelia: stem cells take the lead. Cell Host Microbe (2009) 0.98
Growth in and breakdown of purified rabbit small intestinal mucin by Yersinia enterocolitica. Infect Immun (1993) 0.97
EspM2 is a RhoA guanine nucleotide exchange factor. Cell Microbiol (2009) 0.97
TagA is a secreted protease of Vibrio cholerae that specifically cleaves mucin glycoproteins. Microbiology (2010) 0.97
beta-Catenin stabilization imparts crypt progenitor phenotype to hyperproliferating colonic epithelia. Exp Cell Res (2008) 0.97
Vibrio parahaemolyticus inhibition of Rho family GTPase activation requires a functional chromosome I type III secretion system. Infect Immun (2008) 0.96
EspM inhibits pedestal formation by enterohaemorrhagic Escherichia coli and enteropathogenic E. coli and disrupts the architecture of a polarized epithelial monolayer. Cell Microbiol (2009) 0.94
Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle. Cell Microbiol (2006) 0.94
Interleukin-1 receptor phosphorylation activates Rho kinase to disrupt human gastric tight junctional claudin-4 during Helicobacter pylori infection. Cell Microbiol (2010) 0.93
Tight junctional disruption and apoptosis in an in vitro model of Citrobacter rodentium infection. Microb Pathog (2008) 0.88
Protective role of Akt2 in Salmonella enterica serovar typhimurium-induced gastroenterocolitis. Infect Immun (2011) 0.86
The bacterial virulence factor lymphostatin compromises intestinal epithelial barrier function by modulating rho GTPases. Am J Pathol (2009) 0.86
Differential regulation of ERK1/2 and p38 MAP kinases in VacA-induced apoptosis of gastric epithelial cells. Am J Physiol Gastrointest Liver Physiol (2007) 0.81
Programmed cell death and cell extrusion in rat duodenum: a study of expression and activation of caspase-3 in relation to C-jun phosphorylation, DNA fragmentation and apoptotic morphology. Histochem Cell Biol (2005) 0.78
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Escape of intracellular Shigella from autophagy. Science (2004) 6.64
Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity (2009) 6.24
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog (2007) 4.73
Listeria monocytogenes ActA-mediated escape from autophagic recognition. Nat Cell Biol (2009) 3.05
Grb2 is a key mediator of helicobacter pylori CagA protein activities. Mol Cell (2002) 2.80
Intestinal villous M cells: an antigen entry site in the mucosal epithelium. Proc Natl Acad Sci U S A (2004) 2.75
Role of Peyer's patches in the induction of Helicobacter pylori-induced gastritis. Proc Natl Acad Sci U S A (2007) 2.44
Helicobacter pylori dampens gut epithelial self-renewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach. Cell Host Microbe (2007) 2.41
Shigella targets epithelial tricellular junctions and uses a noncanonical clathrin-dependent endocytic pathway to spread between cells. Cell Host Microbe (2012) 2.30
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response. Nature (2012) 1.99
Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammation. Cell Host Microbe (2009) 1.96
Microtubule-severing activity of Shigella is pivotal for intercellular spreading. Science (2006) 1.85
Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration. J Exp Med (2008) 1.76
Cell death and infection: a double-edged sword for host and pathogen survival. J Cell Biol (2011) 1.69
Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis. Proc Natl Acad Sci U S A (2010) 1.67
Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion. J Exp Med (2005) 1.66
Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery. Nat Cell Biol (2006) 1.64
Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1. EMBO J (2004) 1.64
Analysis of flowering pathway integrators in Arabidopsis. Plant Cell Physiol (2005) 1.61
A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response. Nat Cell Biol (2009) 1.60
Retracted NF-kappaB activation by Helicobacter pylori requires Akt-mediated phosphorylation of p65. BMC Microbiol (2009) 1.59
The versatility of Shigella effectors. Nat Rev Microbiol (2008) 1.58
Targeting of enteropathogenic Escherichia coli EspF to host mitochondria is essential for bacterial pathogenesis: critical role of the 16th leucine residue in EspF. J Biol Chem (2004) 1.57
Structural definition on the surface of Helicobacter pylori type IV secretion apparatus. Cell Microbiol (2003) 1.54
Bicarbonate ion stimulates the expression of locus of enterocyte effacement-encoded genes in enterohemorrhagic Escherichia coli O157:H7. Infect Immun (2002) 1.54
Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling. Blood (2007) 1.52
A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling. Cell (2007) 1.51
Bacterial interactions with the host epithelium. Cell Host Microbe (2010) 1.48
Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. Nature (2009) 1.45
BabA-mediated adherence is a potentiator of the Helicobacter pylori type IV secretion system activity. J Biol Chem (2011) 1.33
Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels. J Exp Med (2012) 1.33
IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells. Its activity to promote membrane ruffling via Rac1 and Cdc42 activation. J Biol Chem (2005) 1.33
A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens. Cell Host Microbe (2011) 1.31
Shigella Spa32 is an essential secretory protein for functional type III secretion machinery and uniformity of its needle length. J Bacteriol (2002) 1.29
Shigella Spa33 is an essential C-ring component of type III secretion machinery. J Biol Chem (2005) 1.28
Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo. Cancer Res (2009) 1.28
Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1. J Immunol (2009) 1.28
Shigella deliver an effector protein to trigger host microtubule destabilization, which promotes Rac1 activity and efficient bacterial internalization. EMBO J (2002) 1.27
Inflammation-induced interstitial migration of effector CD4⁺ T cells is dependent on integrin αV. Nat Immunol (2013) 1.24
AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes. Proc Natl Acad Sci U S A (2006) 1.20
The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection. Cell Host Microbe (2013) 1.20
Shigella effector IpaH9.8 binds to a splicing factor U2AF(35) to modulate host immune responses. Biochem Biophys Res Commun (2005) 1.20
Increased adherence to Caco-2 cells caused by disruption of the yhiE and yhiF genes in enterohemorrhagic Escherichia coli O157:H7. Infect Immun (2003) 1.18
Leukocyte integrins and their ligand interactions. Immunol Res (2009) 1.18
Distribution of the secondary type III secretion system locus found in enterohemorrhagic Escherichia coli O157:H7 isolates among Shiga toxin-producing E. coli strains. J Clin Microbiol (2003) 1.18
SUPPRESSOR OF FRIGIDA3 encodes a nuclear ACTIN-RELATED PROTEIN6 required for floral repression in Arabidopsis. Plant Cell (2005) 1.17
New animal model of shigellosis in the Guinea pig: its usefulness for protective efficacy studies. J Immunol (2007) 1.17
Intracellular survival of Shigella. Cell Microbiol (2006) 1.16
A novel caspase-1/toll-like receptor 4-independent pathway of cell death induced by cytosolic Shigella in infected macrophages. J Biol Chem (2005) 1.16
Species-specific cell adhesion of enteropathogenic Escherichia coli is mediated by type IV bundle-forming pili. Cell Microbiol (2002) 1.15
Neural Wiskott-Aldrich syndrome protein (N-WASP) is the specific ligand for Shigella VirG among the WASP family and determines the host cell type allowing actin-based spreading. Cell Microbiol (2002) 1.15
Outside-in signal transmission by conformational changes in integrin Mac-1. J Immunol (2009) 1.14
Transition from rolling to firm adhesion can be mimicked by extension of integrin alphaLbeta2 in an intermediate affinity state. J Biol Chem (2006) 1.12
Shigella are versatile mucosal pathogens that circumvent the host innate immune system. Curr Opin Immunol (2011) 1.11
Recombinant human activated protein C inhibits integrin-mediated neutrophil migration. Blood (2009) 1.11
Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN. J Exp Med (2009) 1.11
Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2. Proc Natl Acad Sci U S A (2006) 1.10