p53-Dependent subcellular proteome localization following DNA damage.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMC 3229981)

Published in Proteomics on November 02, 2010

Authors

François-Michel Boisvert1, Angus I Lamond

Author Affiliations

1: Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, MSI/WTB/JBC Complex, Dundee, UK.

Articles citing this

The nucleolus under stress. Mol Cell (2010) 3.63

A quantitative spatial proteomics analysis of proteome turnover in human cells. Mol Cell Proteomics (2011) 2.22

Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis. Mol Cell (2012) 1.24

Dysregulation of RNA polymerase I transcription during disease. Biochim Biophys Acta (2012) 1.16

The nucleolus—guardian of cellular homeostasis and genome integrity. Chromosoma (2013) 1.14

Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. Mol Cell Proteomics (2011) 1.07

Perturbations at the ribosomal genes loci are at the centre of cellular dysfunction and human disease. Cell Biosci (2014) 0.93

The role of tumor protein 53 mutations in common human cancers and targeting the murine double minute 2-p53 interaction for cancer therapy. Iran J Med Sci (2012) 0.88

Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus. PLoS One (2012) 0.87

Cytotopic localization by long noncoding RNAs. Curr Opin Cell Biol (2012) 0.86

Bioanalysis of eukaryotic organelles. Chem Rev (2013) 0.86

Nsi1 plays a significant role in the silencing of ribosomal DNA in Saccharomyces cerevisiae. Nucleic Acids Res (2012) 0.84

Label-free protein quantification for plant Golgi protein localization and abundance. Plant Physiol (2014) 0.83

The role of Lamin A in cytoskeleton organization in colorectal cancer cells: a proteomic investigation. Nucleus (2011) 0.82

Quantitative nucleolar proteomics reveals nuclear re-organization during stress- induced senescence in mouse fibroblast. BMC Cell Biol (2011) 0.79

Insulin/IGF1-PI3K-dependent nucleolar localization of a glycolytic enzyme--phosphoglycerate mutase 2, is necessary for proper structure of nucleolus and RNA synthesis. Oncotarget (2015) 0.75

The seven faces of SIRT7. Transcription (2017) 0.75

SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. Nucleic Acids Res (2017) 0.75

Articles cited by this

Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem (1996) 45.70

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol (2008) 38.00

Surfing the p53 network. Nature (2000) 35.36

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics (2002) 30.58

Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science (1998) 17.91

Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap. Mol Cell Proteomics (2005) 10.60

Signaling to p53: breaking the MDM2-p53 circuit. Cell (1998) 8.63

Nucleolar proteome dynamics. Nature (2005) 7.32

Directed proteomic analysis of the human nucleolus. Curr Biol (2002) 7.04

Functional and quantitative proteomics using SILAC. Nat Rev Mol Cell Biol (2006) 6.25

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses. EMBO J (2003) 5.48

Regulation of HDM2 activity by the ribosomal protein L11. Cancer Cell (2003) 5.44

A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC). Nat Protoc (2006) 5.21

A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics. Nat Protoc (2009) 4.84

Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins. Curr Biol (2007) 3.55

Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes. J Cell Biol (2008) 3.53

Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23. Mol Cell Biol (2004) 3.26

Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6. Science (2000) 3.07

Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction. Nat Cell Biol (2009) 2.97

Properties of 13C-substituted arginine in stable isotope labeling by amino acids in cell culture (SILAC). J Proteome Res (2003) 2.51

Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis. Mol Cell (2005) 2.46

RNA-polymerase-I-directed rDNA transcription, life and works. Trends Biochem Sci (2005) 2.13

Sensing cellular stress: another new function for the nucleolus? Sci STKE (2004) 2.09

A quantitative proteomics analysis of subcellular proteome localization and changes induced by DNA damage. Mol Cell Proteomics (2009) 1.74

High confidence determination of specific protein-protein interactions using quantitative mass spectrometry. Curr Opin Biotechnol (2008) 1.72

A SILAC-based DNA protein interaction screen that identifies candidate binding proteins to functional DNA elements. Genome Res (2008) 1.60

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors. Cancer Res (2010) 1.52

Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest. J Biol Chem (2006) 1.29

p53 targets identified by protein expression profiling. Proc Natl Acad Sci U S A (2007) 1.23

Silencing of ribosomal protein S9 elicits a multitude of cellular responses inhibiting the growth of cancer cells subsequent to p53 activation. PLoS One (2010) 1.16

Distinct roles of RECQ1 in the maintenance of genomic stability. DNA Repair (Amst) (2010) 1.05

How the nucleolar sequestration of p53 protein or its interplayers contributes to its (re)-activation. Ann N Y Acad Sci (2003) 0.92

Inhibition of the p53-MDM2 interaction by adenovirus delivery of ribosomal protein L23 stabilizes p53 and induces cell cycle arrest and apoptosis in gastric cancer. J Gene Med (2010) 0.85

Articles by these authors

Nucleolar proteome dynamics. Nature (2005) 7.32

The multifunctional nucleolus. Nat Rev Mol Cell Biol (2007) 7.08

Directed proteomic analysis of the human nucleolus. Curr Biol (2002) 7.04

Large-scale proteomic analysis of the human spliceosome. Genome Res (2002) 5.75

Paraspeckles: a novel nuclear domain. Curr Biol (2002) 4.19

The nucleolus under stress. Mol Cell (2010) 3.63

Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins. Curr Biol (2007) 3.55

Cajal body dynamics and association with chromatin are ATP-dependent. Nat Cell Biol (2002) 3.28

Nuclear speckles. Cold Spring Harb Perspect Biol (2011) 3.04

Cajal bodies: a long history of discovery. Annu Rev Cell Dev Biol (2005) 2.92

Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. Nat Cell Biol (2010) 2.91

Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics. Mol Cell Proteomics (2006) 2.64

P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner. Mol Biol Cell (2005) 2.53

Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability. J Cell Biol (2006) 2.33

A quantitative spatial proteomics analysis of proteome turnover in human cells. Mol Cell Proteomics (2011) 2.22

Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis. Nat Cell Biol (2006) 2.16

Human miRNA precursors with box H/ACA snoRNA features. PLoS Comput Biol (2009) 2.06

Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions. Mol Biol Cell (2004) 2.02

Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells. J Cell Biol (2004) 1.98

Splicing regulation at the second catalytic step by Sex-lethal involves 3' splice site recognition by SPF45. Cell (2002) 1.94

NOPdb: Nucleolar Proteome Database--2008 update. Nucleic Acids Res (2008) 1.93

A proteomic study of SUMO-2 target proteins. J Biol Chem (2004) 1.92

Time-lapse imaging reveals dynamic relocalization of PP1gamma throughout the mammalian cell cycle. Mol Biol Cell (2003) 1.78

A quantitative proteomics analysis of subcellular proteome localization and changes induced by DNA damage. Mol Cell Proteomics (2009) 1.74

Cajal bodies and coilin--moving towards function. J Cell Biol (2002) 1.69

NOPdb: Nucleolar Proteome Database. Nucleic Acids Res (2006) 1.68

Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins. J Cell Biol (2007) 1.58

High-resolution whole-genome sequencing reveals that specific chromatin domains from most human chromosomes associate with nucleoli. Mol Biol Cell (2010) 1.56

Mitotic phosphatases: no longer silent partners. Curr Opin Cell Biol (2006) 1.55

Guidelines for reporting the use of gel electrophoresis in proteomics. Nat Biotechnol (2008) 1.54

Paraspeckles. Cold Spring Harb Perspect Biol (2010) 1.48

3D3/lyric: a novel transmembrane protein of the endoplasmic reticulum and nuclear envelope, which is also present in the nucleolus. Exp Cell Res (2004) 1.48

Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo. J Cell Sci (2003) 1.44

The nucleolus. J Cell Sci (2005) 1.42

Characterization and prediction of protein nucleolar localization sequences. Nucleic Acids Res (2010) 1.40

Identification of human miRNA precursors that resemble box C/D snoRNAs. Nucleic Acids Res (2011) 1.35

UV-induced fragmentation of Cajal bodies. J Cell Biol (2006) 1.34

Bioinformatic analysis of the nucleolus. Biochem J (2003) 1.30

Stable-isotope labeling with amino acids in nematodes. Nat Methods (2011) 1.28

Establishment of a protein frequency library and its application in the reliable identification of specific protein interaction partners. Mol Cell Proteomics (2009) 1.24

Quantitative analysis of chromatin compaction in living cells using FLIM-FRET. J Cell Biol (2009) 1.24

Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation. Mol Cell Proteomics (2011) 1.22

Displacement affinity chromatography of protein phosphatase one (PP1) complexes. BMC Biochem (2008) 1.21

Large-scale isolation of Cajal bodies from HeLa cells. Mol Biol Cell (2002) 1.20

Global subcellular characterization of protein degradation using quantitative proteomics. Mol Cell Proteomics (2012) 1.17

Detecting protein-protein interactions in vivo with FRET using multiphoton fluorescence lifetime imaging microscopy (FLIM). Curr Protoc Cytom (2007) 1.16

Proteomics analysis of the nucleolus in adenovirus-infected cells. Mol Cell Proteomics (2009) 1.16

In vivo analysis of NHPX reveals a novel nucleolar localization pathway involving a transient accumulation in splicing speckles. J Cell Biol (2002) 1.14

Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome. Biochem J (2005) 1.14

PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192. Dev Cell (2013) 1.12

A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells. Elife (2014) 1.10

Protein phosphatase 4 interacts with the Survival of Motor Neurons complex and enhances the temporal localisation of snRNPs. J Cell Sci (2003) 1.09

SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly. Nucleic Acids Res (2005) 1.08

The dynamics of the nucleolus. Crit Rev Eukaryot Gene Expr (2003) 1.08

Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. Mol Cell Proteomics (2011) 1.07

FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35. RNA (2005) 1.06

Human box C/D snoRNA processing conservation across multiple cell types. Nucleic Acids Res (2011) 1.04

Characterization of native protein complexes and protein isoform variation using size-fractionation-based quantitative proteomics. Mol Cell Proteomics (2013) 1.04

Where in the cell is the minor spliceosome? Proc Natl Acad Sci U S A (2008) 1.03

Reversible accumulation of PEGylated single-walled carbon nanotubes in the mammalian nucleus. ACS Nano (2008) 1.03

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice. EMBO Rep (2010) 1.02

Toward a high-resolution view of nuclear dynamics. Science (2007) 1.01

Spatial mapping of splicing factor complexes involved in exon and intron definition. J Cell Biol (2008) 1.01

A novel function for human factor C1 (HCF-1), a host protein required for herpes simplex virus infection, in pre-mRNA splicing. EMBO J (2002) 0.98

Identification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21. Mol Cell (2013) 0.97

A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58. Mol Cell (2010) 0.97

RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits. Mol Biol Cell (2010) 0.97

The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G. Biochim Biophys Acta (2007) 0.96

The serine/arginine-rich protein SF2/ASF regulates protein sumoylation. Proc Natl Acad Sci U S A (2010) 0.95

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway. Mol Cell Proteomics (2011) 0.95

Perturbation of chromatin structure globally affects localization and recruitment of splicing factors. PLoS One (2012) 0.94

Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint. Mol Cell Proteomics (2011) 0.94

Analysis of human small nucleolar RNAs (snoRNA) and the development of snoRNA modulator of gene expression vectors. Mol Biol Cell (2010) 0.94

Mass spectrometry-based immuno-precipitation proteomics - the user's guide. Proteomics (2011) 0.91

Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus. J Biol Chem (2005) 0.89

An intranucleolar body associated with rDNA. Chromosoma (2011) 0.89

hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: structural and functional studies. Proteins (2011) 0.88

Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1. Nucleic Acids Res (2003) 0.85

Nuclear organisation and subnuclear bodies. Prog Mol Subcell Biol (2004) 0.85

hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing. Biochem Biophys Res Commun (2003) 0.84

Plant SILAC: stable-isotope labelling with amino acids of arabidopsis seedlings for quantitative proteomics. PLoS One (2013) 0.83

Nuclear functions in space and time: gene expression in a dynamic, constrained environment. FEBS Lett (2008) 0.83

RNA polymerase II transcription in living color. Nat Struct Mol Biol (2007) 0.83

Cleaning up the masses: exclusion lists to reduce contamination with HPLC-MS/MS. J Proteomics (2013) 0.83

A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II. J Cell Sci (2014) 0.82

Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4. J Biol Chem (2009) 0.82

Modulation of Higher Order Chromatin Conformation in Mammalian Cell Nuclei Can Be Mediated by Polyamines and Divalent Cations. PLoS One (2013) 0.80

Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing. Biochem J (2011) 0.80

Analysis of human protein replacement stable cell lines established using snoMEN-PR vector. PLoS One (2013) 0.79

A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomics. Nucleus (2011) 0.78

FMN2 is a novel regulator of the cyclin-dependent kinase inhibitor p21. Cell Cycle (2013) 0.77

The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition. FEBS Lett (2010) 0.76

PNAC: a protein nucleolar association classifier. BMC Genomics (2011) 0.76

Inhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNA. PLoS One (2012) 0.75

Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs. Nature (2017) 0.75

Nuclear processes controlled by molecular machines. Genome Biol (2002) 0.75

Identification of small molecule inhibitors of pre-mRNA splicing. J Biol Chem (2015) 0.75

Time-lapse imaging of nuclear bodies. Methods Mol Biol (2015) 0.75