Published in EMBO J on November 16, 2010
RNA granules in germ cells. Cold Spring Harb Perspect Biol (2011) 1.80
Translational control in cellular and developmental processes. Nat Rev Genet (2012) 1.39
Scd6 targets eIF4G to repress translation: RGG motif proteins as a class of eIF4G-binding proteins. Mol Cell (2012) 1.18
Global regulation of mRNA translation and stability in the early Drosophila embryo by the Smaug RNA-binding protein. Genome Biol (2014) 1.15
CUP promotes deadenylation and inhibits decapping of mRNA targets. Genes Dev (2011) 1.14
mRNA localization and translational control in Drosophila oogenesis. Cold Spring Harb Perspect Biol (2012) 1.06
Smaug1 mRNA-silencing foci respond to NMDA and modulate synapse formation. J Cell Biol (2011) 1.00
microRNA-independent recruitment of Argonaute 1 to nanos mRNA through the Smaug RNA-binding protein. EMBO Rep (2012) 0.99
From cis-regulatory elements to complex RNPs and back. Cold Spring Harb Perspect Biol (2012) 0.98
Synaptic activity regulated mRNA-silencing foci for the fine tuning of local protein synthesis at the synapse. Commun Integr Biol (2012) 0.92
Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects. Front Genet (2014) 0.91
The Maternal-to-Zygotic Transition During Vertebrate Development: A Model for Reprogramming. Curr Top Dev Biol (2015) 0.89
Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling. Proc Natl Acad Sci U S A (2014) 0.88
Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing. Nucleic Acids Res (2013) 0.86
Smaug/SAMD4A restores translational activity of CUGBP1 and suppresses CUG-induced myopathy. PLoS Genet (2013) 0.83
A single Drosophila embryo extract for the study of mitosis ex vivo. Nat Protoc (2013) 0.82
Identification of Drosophila and human 7-methyl GMP-specific nucleotidases. J Biol Chem (2012) 0.81
Cryopreservation Causes Genetic and Epigenetic Changes in Zebrafish Genital Ridges. PLoS One (2013) 0.80
Smaug destroys a huge treasure. Genome Biol (2014) 0.77
Germ Line Versus Soma in the Transition from Egg to Embryo. Curr Top Dev Biol (2015) 0.77
Zfrp8 forms a complex with fragile-X mental retardation protein and regulates its localization and function. Dev Biol (2016) 0.76
Smaug: an unexpected journey into the mechanisms of post-transcriptional regulation. Fly (Austin) (2013) 0.75
Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch. RNA (2017) 0.75
The mechanism of eukaryotic translation initiation and principles of its regulation. Nat Rev Mol Cell Biol (2010) 11.19
P bodies and the control of mRNA translation and degradation. Mol Cell (2007) 9.98
P bodies: at the crossroads of post-transcriptional pathways. Nat Rev Mol Cell Biol (2007) 7.96
Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G. EMBO J (1996) 7.28
Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol (2006) 6.41
General translational repression by activators of mRNA decapping. Cell (2005) 6.40
Initiation of protein synthesis from the A site of the ribosome. Cell (2000) 4.56
MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F. Science (2007) 4.33
Oskar organizes the germ plasm and directs localization of the posterior determinant nanos. Cell (1991) 4.33
Induction of germ cell formation by oskar. Nature (1992) 4.23
Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing. Genes Dev (2007) 3.92
Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation. Nature (2007) 3.77
Me31B silences translation of oocyte-localizing RNAs through the formation of cytoplasmic RNP complex during Drosophila oogenesis. Development (2001) 3.22
Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies. Neuron (2006) 3.05
Maskin is a CPEB-associated factor that transiently interacts with elF-4E. Mol Cell (1999) 3.05
Translational regulation and RNA localization in Drosophila oocytes and embryos. Annu Rev Genet (2001) 2.99
Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA. Genes Dev (2003) 2.89
Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor. Cell (2004) 2.84
A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP. Cell (2005) 2.80
Translational regulation of nanos by RNA localization. Nature (1994) 2.77
Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles. Cell (2006) 2.77
Nanos is the localized posterior determinant in Drosophila. Cell (1991) 2.70
Drosophila argonaute1 and argonaute2 employ distinct mechanisms for translational repression. Mol Cell (2009) 2.69
Drosophila cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis. Dev Cell (2004) 2.66
SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase. Dev Cell (2007) 2.64
Localization of nanos RNA controls embryonic polarity. Cell (1992) 2.53
A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay. J Cell Biol (2005) 2.51
A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila. EMBO J (2004) 2.40
Xp54, the Xenopus homologue of human RNA helicase p54, is an integral component of stored mRNP particles in oocytes. Nucleic Acids Res (1997) 2.31
The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators. Nat Struct Biol (2003) 2.29
smaug protein represses translation of unlocalized nanos mRNA in the Drosophila embryo. Genes Dev (1996) 2.22
Polyadenylation of c-mos mRNA as a control point in Xenopus meiotic maturation. Nature (1995) 2.21
Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila. Mol Cell (1999) 2.21
A conserved role of a DEAD box helicase in mRNA masking. RNA (2001) 2.20
Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo. Curr Biol (2005) 2.18
Translational control of maternal Cyclin B mRNA by Nanos in the Drosophila germline. Development (2007) 2.16
Efficient protein trafficking requires trailer hitch, a component of a ribonucleoprotein complex localized to the ER in Drosophila. Dev Cell (2005) 2.14
The Nanos gradient in Drosophila embryos is generated by translational regulation. Genes Dev (1996) 2.12
Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression. EMBO J (2003) 2.03
Joint action of two RNA degradation pathways controls the timing of maternal transcript elimination at the midblastula transition in Drosophila melanogaster. EMBO J (1999) 2.02
Oskar allows nanos mRNA translation in Drosophila embryos by preventing its deadenylation by Smaug/CCR4. Development (2006) 1.97
Translational control of the embryonic cell cycle. Cell (2002) 1.93
Dissolution of the maskin-eIF4E complex by cytoplasmic polyadenylation and poly(A)-binding protein controls cyclin B1 mRNA translation and oocyte maturation. EMBO J (2002) 1.92
Translational control of oskar generates short OSK, the isoform that induces pole plasma assembly. Development (1995) 1.85
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression. Mol Cell (2009) 1.82
CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes. J Biol Chem (2007) 1.79
Cup is an eIF4E binding protein required for both the translational repression of oskar and the recruitment of Barentsz. J Cell Biol (2003) 1.70
Role for mRNA localization in translational activation but not spatial restriction of nanos RNA. Development (1999) 1.66
Translational repression by deadenylases. J Biol Chem (2010) 1.62
Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat Struct Mol Biol (2006) 1.61
Remodeling of ribonucleoprotein complexes with DExH/D RNA helicases. Nucleic Acids Res (2006) 1.61
A conserved 90 nucleotide element mediates translational repression of nanos RNA. Development (1996) 1.59
Overexpression of oskar directs ectopic activation of nanos and presumptive pole cell formation in Drosophila embryos. Cell (1992) 1.59
Synthesis of the posterior determinant Nanos is spatially restricted by a novel cotranslational regulatory mechanism. Curr Biol (2000) 1.57
Position of the CrPV IRES on the 40S subunit and factor dependence of IRES/80S ribosome assembly. EMBO Rep (2004) 1.53
RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes. J Biol Chem (2006) 1.52
Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p. Nat Struct Mol Biol (2006) 1.45
Mechanisms of translational regulation in Drosophila. Biol Cell (2005) 1.38
Glorund, a Drosophila hnRNP F/H homolog, is an ovarian repressor of nanos translation. Dev Cell (2006) 1.38
Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly. Mol Biol Cell (2009) 1.36
Setting the stage for development: mRNA translation and stability during oocyte maturation and egg activation in Drosophila. Dev Dyn (2005) 1.34
Smaug, a novel and conserved protein, contributes to repression of nanos mRNA translation in vitro. RNA (1999) 1.34
RNA-binding proteins in early development. Crit Rev Biochem Mol Biol (2005) 1.33
Global analyses of mRNA translational control during early Drosophila embryogenesis. Genome Biol (2007) 1.30
Maternal mRNA from clam oocytes can be specifically unmasked in vitro by antisense RNA complementary to the 3'-untranslated region. Genes Dev (1990) 1.28
Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes. Mol Cell Biol (2008) 1.22
Synthesis and function of Mos: the control switch of vertebrate oocyte meiosis. Bioessays (1997) 1.19
A test for masked message: the template activity of messenger ribonucleoprotein particles isolated from sea urchine eggs. Dev Biol (1978) 1.14
Translation initiation factors are not required for Dicistroviridae IRES function in vivo. RNA (2009) 1.12
twin, a CCR4 homolog, regulates cyclin poly(A) tail length to permit Drosophila oogenesis. Development (2005) 1.12
Cup is a nucleocytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development. Proc Natl Acad Sci U S A (2004) 1.11
Host and viral translational mechanisms during cricket paralysis virus infection. J Virol (2009) 1.09
bicaudal encodes the Drosophila beta NAC homolog, a component of the ribosomal translational machinery*. Development (2000) 1.07
"Masked" forms of mRNA. Curr Top Dev Biol (1966) 1.07
Rapid ATP-dependent deadenylation of nanos mRNA in a cell-free system from Drosophila embryos. J Biol Chem (2006) 1.06
Translation of maternal messenger ribonucleoprotein particles from sea urchin in a cell-free system from unfertilized eggs and product analysis. Dev Biol (1978) 1.06
RNA recognition by the Vts1p SAM domain. Nat Struct Mol Biol (2006) 1.05
Translational control in early development: CPEB, P-bodies and germinal granules. Biochem Soc Trans (2008) 1.03
Regulating translation of maternal messages: multiple repression mechanisms. Trends Cell Biol (2007) 1.02
Storage of messenger RNA in eukaryotes: envelopment with protein, translational barrier at 5' side, or conformational masking by 3' side? Mol Reprod Dev (1994) 1.01
A translation regulatory particle containing the Xenopus oocyte Y box protein mRNP3+4. J Biol Chem (1997) 0.98
Fertilization triggers unmasking of maternal mRNAs in sea urchin eggs. Mol Cell Biol (1987) 0.91
Cell-free deadenylation assays with Drosophila embryo extracts. Methods Enzymol (2008) 0.81
Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures. EMBO J (2002) 6.08
Messenger RNA turnover in eukaryotes: pathways and enzymes. Crit Rev Biochem Mol Biol (2004) 3.67
A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila. EMBO J (2004) 2.40
Structure and function of poly(A) binding proteins. Biochim Biophys Acta (2004) 2.28
The intranuclear mobility of messenger RNA binding proteins is ATP dependent and temperature sensitive. J Cell Biol (2002) 1.68
Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. RNA (2008) 1.63
Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA. EMBO J (2003) 1.55
Poly(A) tail length is controlled by the nuclear poly(A)-binding protein regulating the interaction between poly(A) polymerase and the cleavage and polyadenylation specificity factor. J Biol Chem (2009) 1.54
An essential cytoplasmic function for the nuclear poly(A) binding protein, PABP2, in poly(A) tail length control and early development in Drosophila. Dev Cell (2005) 1.53
Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation. RNA (2010) 1.51
Control of poly(A) tail length. Wiley Interdiscip Rev RNA (2010) 1.41
Control of poly(A) polymerase level is essential to cytoplasmic polyadenylation and early development in Drosophila. EMBO J (2002) 1.29
The RNA binding domains of the nuclear poly(A)-binding protein. J Biol Chem (2003) 1.27
Structural insight into poly(A) binding and catalytic mechanism of human PARN. EMBO J (2005) 1.24
Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming. RNA (2012) 1.22
Asymmetric arginine dimethylation of heterogeneous nuclear ribonucleoprotein K by protein-arginine methyltransferase 1 inhibits its interaction with c-Src. J Biol Chem (2006) 1.13
Rapid ATP-dependent deadenylation of nanos mRNA in a cell-free system from Drosophila embryos. J Biol Chem (2006) 1.06
Degradation of hsp70 and other mRNAs in Drosophila via the 5' 3' pathway and its regulation by heat shock. J Biol Chem (2007) 1.06
The Drosophila melanogaster Gene cg4930 Encodes a High Affinity Inhibitor for Endonuclease G. J Biol Chem (2009) 1.05
Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior. J Biol Chem (2008) 1.02
Trinucleotide expansions leading to an extended poly-L-alanine segment in the poly (A) binding protein PABPN1 cause fibril formation. Protein Sci (2003) 0.95
Type I Arginine Methyltransferases PRMT1 and PRMT-3 Act Distributively. J Biol Chem (2009) 0.95
Equilibrium studies on the association of the nuclear poly(A) binding protein with poly(A) of different lengths. Biochemistry (2002) 0.89
Hofmeister salts and potential therapeutic compounds accelerate in vitro fibril formation of the N-terminal domain of PABPN1 containing a disease-causing alanine extension. Biochemistry (2008) 0.87
Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition. Nucleic Acids Res (2009) 0.87
Arginine methylation of the nuclear poly(a) binding protein weakens the interaction with its nuclear import receptor, transportin. J Biol Chem (2011) 0.83
Cell-free deadenylation assays with Drosophila embryo extracts. Methods Enzymol (2008) 0.81
Identification of Drosophila and human 7-methyl GMP-specific nucleotidases. J Biol Chem (2012) 0.81
Binding of the heterogeneous ribonucleoprotein K (hnRNP K) to the Epstein-Barr virus nuclear antigen 2 (EBNA2) enhances viral LMP2A expression. PLoS One (2012) 0.80
Biophysical and biochemical analysis of hnRNP K: arginine methylation, reversible aggregation and combinatorial binding to nucleic acids. Biol Chem (2014) 0.79
Smaug destroys a huge treasure. Genome Biol (2014) 0.77
Wrong PH for RNA degradation. Nat Struct Mol Biol (2007) 0.77
Methylation of the nuclear poly(A)-binding protein by type I protein arginine methyltransferases - how and why. Biol Chem (2013) 0.77
Peptide backbone conformation affects the substrate preference of protein arginine methyltransferase I. Biochemistry (2012) 0.77
Simple methods for the 3' biotinylation of RNA. RNA (2014) 0.75
Assaying mRNA deadenylation in vitro. Methods Mol Biol (2014) 0.75
Predicted alterations in tertiary structure of the N-terminus of Na(+)/K(+)-ATPase alpha-subunit caused by phosphorylation or acidic replacement of the PKC phosphorylation site Ser-23. Cell Biochem Biophys (2002) 0.75
An ancient oxidoreductase making differential use of its cofactors. Biol Chem (2014) 0.75
Assaying mRNA deadenylation in vivo. Methods Mol Biol (2014) 0.75