Published in Mol Cell Biol on April 01, 1990
Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol Cell Biol (1991) 3.70
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J (1999) 3.05
The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase. EMBO J (1996) 2.22
TGF-β: duality of function between tumor prevention and carcinogenesis. J Natl Cancer Inst (2014) 2.08
Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta. Mol Cell Biol (1999) 2.08
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Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma. Am J Pathol (2004) 1.77
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Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis. J Pathol (2003) 1.71
SPARC inhibits epithelial cell proliferation in part through stimulation of the transforming growth factor-beta-signaling system. Mol Biol Cell (2003) 1.63
Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene. Proc Natl Acad Sci U S A (1991) 1.63
Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia. Am J Pathol (2001) 1.61
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Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39
Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice. Am J Pathol (2000) 1.39
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The IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site. J Virol (1996) 1.27
Transcriptional and translational regulation of TGF-beta production in response to apoptotic cells. J Immunol (2008) 1.26
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Transforming growth factor beta and cyclosporin A inhibit the inducible activity of the interleukin-2 gene in T cells through a noncanonical octamer-binding site. Mol Cell Biol (1993) 1.19
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Role of elevated plasma transforming growth factor-beta1 levels in wound healing. Am J Pathol (1999) 1.14
Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25. Am J Respir Crit Care Med (2010) 1.14
Ontogenetic transition in fetal wound transforming growth factor-beta regulation correlates with collagen organization. Am J Pathol (2003) 1.13
TGFbeta1 regulates gene expression of its own converting enzyme furin. J Clin Invest (1997) 1.13
Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3. Int J Biochem Cell Biol (2007) 1.11
Transcriptional regulation of the transforming growth factor beta 1 promoter by v-src gene products is mediated through the AP-1 complex. Mol Cell Biol (1990) 1.11
Transforming growth factors beta 1 and 2 transcriptionally regulate human papillomavirus (HPV) type 16 early gene expression in HPV-immortalized human genital epithelial cells. J Virol (1990) 1.11
Control of junB and extracellular matrix protein expression by transforming growth factor-beta 1 is independent of simian virus 40 T antigen-sensitive growth-sensitive growth-inhibitory events. Mol Cell Biol (1991) 1.10
Delayed wound closure in fibromodulin-deficient mice is associated with increased TGF-β3 signaling. J Invest Dermatol (2010) 1.07
Fra-2 mediates oxygen-sensitive induction of transforming growth factor beta in cardiac fibroblasts. Cardiovasc Res (2010) 1.06
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Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells. Biochem J (2004) 1.05
CXC-type chemokines promote myofibroblast phenoconversion and prostatic fibrosis. PLoS One (2012) 1.03
The autoregulatory feedback loop of microRNA-21/programmed cell death protein 4/activation protein-1 (MiR-21/PDCD4/AP-1) as a driving force for hepatic fibrosis development. J Biol Chem (2013) 1.03
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Podoplanin is regulated by AP-1 and promotes platelet aggregation and cell migration in osteosarcoma. Am J Pathol (2011) 1.02
Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3. Proc Natl Acad Sci U S A (1992) 0.98
Localization of Fos and Jun proteins in rat aortic smooth muscle cells after vascular injury. Am J Pathol (1993) 0.98
TGF-beta cooperates with TGF-alpha to induce the self-renewal of normal erythrocytic progenitors: evidence for an autocrine mechanism. EMBO J (1999) 0.97
Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats. Br J Pharmacol (2003) 0.97
Biphasic increase in c-jun mRNA is required for induction of AP-1-mediated gene transcription: differential effects of muscarinic and thrombin receptor activation. Mol Cell Biol (1992) 0.97
Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators. Oncogene (2010) 0.95
Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway. PLoS One (2011) 0.95
Betaglycan is required for the establishment of nephron endowment in the mouse. PLoS One (2011) 0.93
Neovascularization in aged mice: delayed angiogenesis is coincident with decreased levels of transforming growth factor beta1 and type I collagen. Am J Pathol (1998) 0.92
TGF-beta 1 induces phosphorylation of the cyclic AMP responsive element binding protein in ML-CCl64 cells. EMBO J (1991) 0.90
Knockdown of c-Fos suppresses the growth of human colon carcinoma cells in athymic mice. Int J Cancer (2011) 0.88
Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1. FASEB J (2012) 0.87
Glucocorticoids modulate TGF-beta production by human fetal lung fibroblasts. Inflammation (2003) 0.86
Cross-talk between nitric oxide and transforming growth factor-beta1 in malaria. Curr Mol Med (2004) 0.85
Transforming growth factor (TGF)-beta stimulates hepatic jun-B and fos-B proto-oncogenes and decreases albumin mRNA. Ann Surg (1992) 0.85
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Overexpression of transforming growth factor-beta in transgenic mice carrying the human T-cell lymphotropic virus type I tax gene. Mol Cell Biol (1991) 0.84
Retracted Deficiency of cardiomyocyte-specific microRNA-378 contributes to the development of cardiac fibrosis involving a transforming growth factor β (TGFβ1)-dependent paracrine mechanism. J Biol Chem (2014) 0.84
c-Fos/activator protein-1 transactivates wee1 kinase at G(1)/S to inhibit premature mitosis in antigen-specific Th1 cells. EMBO J (2001) 0.84
Inhibition of transforming growth factor-beta production in brain pericytes contributes to cyclosporin A-induced dysfunction of the blood-brain barrier. Cell Mol Neurobiol (2006) 0.82
Negative autoregulation of the neu gene is mediated by a novel enhancer. Mol Cell Biol (1992) 0.82
Mysteries of TGF-β Paradox in Benign and Malignant Cells. Front Oncol (2014) 0.82
Altered functions of alveolar macrophages and NK cells involved in asbestos-related diseases. Environ Health Prev Med (2013) 0.82
Immediate-early gene induction and MAP kinase activation during recovery from metabolic inhibition in cultured cardiac myocytes. J Clin Invest (1995) 0.82
Inhibition of purified CD34+ hematopoietic progenitor cells by human immunodeficiency virus 1 or gp120 mediated by endogenous transforming growth factor beta 1. J Exp Med (1996) 0.82
Glucocorticoids modulate TGF-beta production. Inflammation (2002) 0.81
Oxidative stress is predominant in female but not in male patients with autoimmune thrombocytopenia. Oxid Med Cell Longev (2014) 0.81
TGFβ Contributes to the Anti-inflammatory Effects of Tauroursodeoxycholic Acid on an Animal Model of Acute Neuroinflammation. Mol Neurobiol (2016) 0.80
3,3'-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression. Br J Pharmacol (2013) 0.80
Decreased tumor progression and invasion by a novel anti-cell motility target for human colorectal carcinoma cells. PLoS One (2013) 0.80
The TGFβ receptor-interacting protein km23-1/DYNLRB1 plays an adaptor role in TGFβ1 autoinduction via its association with Ras. J Biol Chem (2012) 0.80
Identification and association of the single nucleotide polymorphisms, C-509T, C+466T and T+869C, of the TGF-β1 gene in patients with asthma and their influence on the mRNA expression level of TGF-β1. Int J Mol Med (2014) 0.79
Pathobiology of renal-specific oxidoreductase/myo-inositol oxygenase in diabetic nephropathy: its implications in tubulointerstitial fibrosis. Am J Physiol Renal Physiol (2010) 0.78
Mutant KRAS Conversion of Conventional T Cells into Regulatory T Cells. Cancer Immunol Res (2016) 0.77
A Signaling Network Controlling Androgenic Repression of c-Fos Protein in Prostate Adenocarcinoma Cells. J Biol Chem (2016) 0.77
Novel application of multi-stimuli network inference to synovial fibroblasts of rheumatoid arthritis patients. BMC Med Genomics (2014) 0.77
Effects of calcium and vitamin D3 on transforming growth factors in rectal mucosa of sporadic colorectal adenoma patients: a randomized controlled trial. Mol Carcinog (2013) 0.77
The TGF-β pathway mediates doxorubicin effects on cardiac endothelial cells. J Mol Cell Cardiol (2015) 0.76
Prevention of experimental autoimmune encephalomyelitis in DA rats by grafting primary skin fibroblasts engineered to express transforming growth factor-beta1. Clin Exp Immunol (2004) 0.75
Time and dose-dependent effects of Labisia pumila on bone oxidative status of postmenopausal osteoporosis rat model. Nutrients (2014) 0.75
A Positive TGF-β/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer. Neoplasia (2016) 0.75
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