PubRank

Sean J Morrison

Author PubWeight™ 301.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 2003 59.17
2 SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005 24.00
3 Efficient tumour formation by single human melanoma cells. Nature 2008 16.35
4 Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003 14.35
5 Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 2006 11.86
6 Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003 11.23
7 Applying the principles of stem-cell biology to cancer. Nat Rev Cancer 2003 8.95
8 Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 2006 8.06
9 Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 2009 7.09
10 Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 2012 6.60
11 Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 2003 6.35
12 Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev 2005 5.78
13 Tumour heterogeneity and cancer cell plasticity. Nature 2013 5.47
14 Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell 2012 5.44
15 Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell 2008 5.07
16 Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature 2007 4.62
17 Uncertainty in the niches that maintain haematopoietic stem cells. Nat Rev Immunol 2008 4.42
18 Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell 2007 4.18
19 Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Nature 2013 4.11
20 Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 2010 3.93
21 Neural crest stem cells persist in the adult gut but undergo changes in self-renewal, neuronal subtype potential, and factor responsiveness. Neuron 2002 3.92
22 Bmi1, stem cells, and senescence regulation. J Clin Invest 2004 3.80
23 Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized. Cancer Cell 2010 3.70
24 Diverse mechanisms regulate stem cell self-renewal. Curr Opin Cell Biol 2004 3.34
25 SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood 2005 3.22
26 Mechanisms of stem cell self-renewal. Annu Rev Cell Dev Biol 2009 3.00
27 Hirschsprung disease is linked to defects in neural crest stem cell function. Science 2003 2.98
28 Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance. Cell Stem Cell 2007 2.96
29 Cell-intrinsic differences between stem cells from different regions of the peripheral nervous system regulate the generation of neural diversity. Neuron 2002 2.85
30 Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. Blood 2006 2.67
31 HIV-1 utilizes the CXCR4 chemokine receptor to infect multipotent hematopoietic stem and progenitor cells. Cell Host Microbe 2011 2.59
32 SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors. Cell Stem Cell 2013 2.47
33 Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice. Proc Natl Acad Sci U S A 2007 2.41
34 Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression. Cell Stem Cell 2012 2.15
35 Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells. Development 2004 1.98
36 Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut. J Clin Invest 2011 1.88
37 mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion. Cell Stem Cell 2010 1.82
38 FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells. Blood 2010 1.78
39 Mechanisms that regulate stem cell aging and life span. Cell Stem Cell 2013 1.73
40 Maintaining hematopoietic stem cells in the vascular niche. Immunity 2006 1.72
41 Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress. Nat Cell Biol 2010 1.71
42 CD144 (VE-cadherin) is transiently expressed by fetal liver hematopoietic stem cells. Blood 2005 1.64
43 CD150- cells are transiently reconstituting multipotent progenitors with little or no stem cell activity. Blood 2008 1.57
44 The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells. Cancer Cell 2008 1.54
45 Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems. Development 2007 1.47
46 Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood 2008 1.45
47 Integrating physiological regulation with stem cell and tissue homeostasis. Neuron 2011 1.41
48 Temporally distinct requirements for endothelin receptor B in the generation and migration of gut neural crest stem cells. Neuron 2003 1.41
49 Hematopoietic stem cells do not depend on N-cadherin to regulate their maintenance. Cell Stem Cell 2009 1.39
50 Sox17 expression confers self-renewal potential and fetal stem cell characteristics upon adult hematopoietic progenitors. Genes Dev 2011 1.36
51 Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder. Cancer Cell 2009 1.36
52 Toward an understanding of the physiological function of Mammalian stem cells. Dev Cell 2005 1.35
53 Spatial differences in hematopoiesis but not in stem cells indicate a lack of regional patterning in definitive hematopoietic stem cells. Dev Biol 2005 1.22
54 Human melanoma metastasis in NSG mice correlates with clinical outcome in patients. Sci Transl Med 2012 1.18
55 Inhibition of AMPK catabolic action by GSK3. Mol Cell 2013 1.18
56 Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells. Development 2010 1.17
57 Lack of population diversity in commonly used human embryonic stem-cell lines. N Engl J Med 2009 1.17
58 An in vivo model to study and manipulate the hematopoietic stem cell niche. Blood 2010 1.11
59 Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo. Dev Biol 2009 1.10
60 Developmental changes in Notch1 and numb expression mediated by local cell-cell interactions underlie progressively increasing delta sensitivity in neural crest stem cells. Dev Biol 2002 1.03
61 Huntingtin Interacting Protein 1 mutations lead to abnormal hematopoiesis, spinal defects and cataracts. Hum Mol Genet 2004 1.01
62 Intrinsic differences among spatially distinct neural crest stem cells in terms of migratory properties, fate determination, and ability to colonize the enteric nervous system. Dev Biol 2006 1.00
63 A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Elife 2013 0.99
64 Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions. Cancer Cell 2012 0.97
65 Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers. Blood 2010 0.96
66 Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice. J Clin Invest 2012 0.96
67 Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci 2010 0.91
68 The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells. Blood Cells Mol Dis 2008 0.89
69 Brain repair by endogenous progenitors. Cell 2002 0.86
70 Stem-cell competition. Nature 2002 0.84
71 Pten-uating neural growth. Nat Med 2002 0.77
72 Erratum: Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma. Nat Commun 2016 0.77
73 Corrigendum: Lens regeneration using endogenous stem cells with gain of visual function. Nature 2016 0.75
74 Crossing the boundaries of sensory neurogenesis. Nat Neurosci 2004 0.75