1
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Common SNPs explain a large proportion of the heritability for human height.
|
Nat Genet
|
2010
|
35.02
|
2
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
3
|
GCTA: a tool for genome-wide complex trait analysis.
|
Am J Hum Genet
|
2010
|
20.73
|
4
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
5
|
Estimating missing heritability for disease from genome-wide association studies.
|
Am J Hum Genet
|
2011
|
8.95
|
6
|
Genome partitioning of genetic variation for complex traits using common SNPs.
|
Nat Genet
|
2011
|
8.57
|
7
|
Prediction of individual genetic risk to disease from genome-wide association studies.
|
Genome Res
|
2007
|
8.48
|
8
|
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
|
Nat Genet
|
2013
|
8.02
|
9
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
10
|
Data and theory point to mainly additive genetic variance for complex traits.
|
PLoS Genet
|
2008
|
7.15
|
11
|
Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.
|
Nat Genet
|
2012
|
5.78
|
12
|
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits.
|
Nat Genet
|
2012
|
5.55
|
13
|
Genomic inflation factors under polygenic inheritance.
|
Eur J Hum Genet
|
2011
|
4.89
|
14
|
The genetic interpretation of area under the ROC curve in genomic profiling.
|
PLoS Genet
|
2010
|
4.58
|
15
|
Predicting unobserved phenotypes for complex traits from whole-genome SNP data.
|
PLoS Genet
|
2008
|
4.57
|
16
|
Reconciling the analysis of IBD and IBS in complex trait studies.
|
Nat Rev Genet
|
2010
|
3.62
|
17
|
A commentary on 'common SNPs explain a large proportion of the heritability for human height' by Yang et al. (2010).
|
Twin Res Hum Genet
|
2010
|
3.37
|
18
|
Pitfalls of predicting complex traits from SNPs.
|
Nat Rev Genet
|
2013
|
3.06
|
19
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
20
|
Genetic contributions to stability and change in intelligence from childhood to old age.
|
Nature
|
2012
|
2.63
|
21
|
Prediction of individual genetic risk of complex disease.
|
Curr Opin Genet Dev
|
2008
|
2.19
|
22
|
Accuracy of genomic selection using stochastic search variable selection in Australian Holstein Friesian dairy cattle.
|
Genet Res (Camb)
|
2009
|
2.05
|
23
|
Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis.
|
Hum Mol Genet
|
2012
|
1.96
|
24
|
Quantification of inbreeding due to distant ancestors and its detection using dense single nucleotide polymorphism data.
|
Genetics
|
2011
|
1.85
|
25
|
Estimation of SNP heritability from dense genotype data.
|
Am J Hum Genet
|
2013
|
1.64
|
26
|
Human population dispersal "Out of Africa" estimated from linkage disequilibrium and allele frequencies of SNPs.
|
Genome Res
|
2011
|
1.64
|
27
|
A better coefficient of determination for genetic profile analysis.
|
Genet Epidemiol
|
2012
|
1.63
|
28
|
High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury.
|
J Appl Physiol (1985)
|
2003
|
1.62
|
29
|
Genome-wide complex trait analysis (GCTA): methods, data analyses, and interpretations.
|
Methods Mol Biol
|
2013
|
1.42
|
30
|
Polymorphic regions affecting human height also control stature in cattle.
|
Genetics
|
2011
|
1.42
|
31
|
Estimation and partition of heritability in human populations using whole-genome analysis methods.
|
Annu Rev Genet
|
2013
|
1.41
|
32
|
The future of livestock breeding: genomic selection for efficiency, reduced emissions intensity, and adaptation.
|
Trends Genet
|
2012
|
1.41
|
33
|
Multi-locus models of genetic risk of disease.
|
Genome Med
|
2010
|
1.33
|
34
|
Unexpected protective role for Toll-like receptor 3 in the arterial wall.
|
Proc Natl Acad Sci U S A
|
2011
|
1.31
|
35
|
Using the realized relationship matrix to disentangle confounding factors for the estimation of genetic variance components of complex traits.
|
Genet Sel Evol
|
2010
|
1.27
|
36
|
Mechanisms of early pulmonary neutrophil sequestration in ventilator-induced lung injury in mice.
|
Am J Physiol Lung Cell Mol Physiol
|
2004
|
1.13
|
37
|
Selection for complex traits leaves little or no classic signatures of selection.
|
BMC Genomics
|
2014
|
1.13
|
38
|
Whole-genome resequencing of two elite sires for the detection of haplotypes under selection in dairy cattle.
|
Proc Natl Acad Sci U S A
|
2012
|
1.08
|
39
|
Additive genetic variation in schizophrenia risk is shared by populations of African and European descent.
|
Am J Hum Genet
|
2013
|
1.07
|
40
|
Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice.
|
Am J Physiol Lung Cell Mol Physiol
|
2007
|
1.06
|
41
|
The use of communal rearing of families and DNA pooling in aquaculture genomic selection schemes.
|
Genet Sel Evol
|
2010
|
1.05
|
42
|
Genetic architecture of body size in mammals.
|
Genome Biol
|
2012
|
1.03
|
43
|
Identification of genomic regions associated with inbreeding depression in Holstein and Jersey dairy cattle.
|
Genet Sel Evol
|
2014
|
1.02
|
44
|
Genome position specific priors for genomic prediction.
|
BMC Genomics
|
2012
|
0.99
|
45
|
Efficacy and safety of inhaled carbon monoxide during pulmonary inflammation in mice.
|
PLoS One
|
2010
|
0.94
|
46
|
B regulatory cells are increased in hypercholesterolaemic mice and protect from lesion development via IL-10.
|
Thromb Haemost
|
2015
|
0.89
|
47
|
Comparing linkage and association analyses in sheep points to a better way of doing GWAS.
|
Genet Res (Camb)
|
2012
|
0.89
|
48
|
Effects of inhaled carbon monoxide on acute lung injury in mice.
|
Am J Physiol Lung Cell Mol Physiol
|
2005
|
0.87
|
49
|
Cattle gain stature.
|
Nat Genet
|
2011
|
0.84
|
50
|
Next generation modeling in GWAS: comparing different genetic architectures.
|
Hum Genet
|
2014
|
0.81
|
51
|
Genetic variants in mammary development, prolactin signalling and involution pathways explain considerable variation in bovine milk production and milk composition.
|
Genet Sel Evol
|
2014
|
0.80
|
52
|
Adaptation of gastrointestinal nematode parasites to host genotype: single locus simulation models.
|
Genet Sel Evol
|
2013
|
0.79
|
53
|
Systems genetics: the added value of gene expression.
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HFSP J
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2010
|
0.79
|
54
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Author reply to A commentary on Pitfalls of predicting complex traits from SNPs.
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Nat Rev Genet
|
2013
|
0.79
|
55
|
A note on permutation tests for genetic association analysis of quantitative traits when variances are heterogeneous.
|
Genet Epidemiol
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2009
|
0.75
|
56
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Kernel methods and haplotypes used in selection of sparse DNA markers for protein yield in dairy cattle.
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Math Biosci
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2013
|
0.75
|