PubRank

Robert G Parton

Author PubWeight™ 229.91‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lipid droplets: a unified view of a dynamic organelle. Nat Rev Mol Cell Biol 2006 6.85
2 Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J Cell Biol 2003 5.45
3 PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell 2008 4.42
4 Role of LBPA and Alix in multivesicular liposome formation and endosome organization. Science 2004 4.35
5 GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway. Dev Cell 2002 4.28
6 APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell 2004 3.95
7 Plasma membrane nanoswitches generate high-fidelity Ras signal transduction. Nat Cell Biol 2007 3.90
8 H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proc Natl Acad Sci U S A 2005 3.78
9 Cells respond to mechanical stress by rapid disassembly of caveolae. Cell 2011 3.55
10 Endosome-to-cytosol transport of viral nucleocapsids. Nat Cell Biol 2005 2.98
11 Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast. J Cell Biol 2008 2.85
12 Caveolin-1 is essential for liver regeneration. Science 2006 2.77
13 Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles. J Cell Biol 2005 2.74
14 Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains. Cell 2010 2.67
15 The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms. PLoS Biol 2004 2.59
16 Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nat Cell Biol 2010 2.51
17 Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway. J Cell Biol 2004 2.31
18 Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. Mol Cell Biol 2005 2.24
19 Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism. J Biol Chem 2005 2.15
20 Ras plasma membrane signalling platforms. Biochem J 2005 2.15
21 Differential sorting and fate of endocytosed GPI-anchored proteins. EMBO J 2002 2.15
22 Cholesterol manipulation by West Nile virus perturbs the cellular immune response. Cell Host Microbe 2007 2.14
23 Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane. Mol Cell Biol 2004 2.09
24 Not just fat: the structure and function of the lipid droplet. Cold Spring Harb Perspect Biol 2011 2.07
25 A novel switch region regulates H-ras membrane orientation and signal output. EMBO J 2008 2.06
26 Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin. J Biol Chem 2003 2.05
27 Flotillins and the PHB domain protein family: rafts, worms and anaesthetics. Traffic 2005 2.01
28 Rab23, a negative regulator of hedgehog signaling, localizes to the plasma membrane and the endocytic pathway. Traffic 2003 1.88
29 Association of stomatin with lipid bodies. J Biol Chem 2004 1.88
30 MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. J Cell Biol 2009 1.87
31 Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim Biophys Acta 2005 1.87
32 Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol. Mol Biol Cell 2004 1.86
33 Cholesterol and fatty acids regulate dynamic caveolin trafficking through the Golgi complex and between the cell surface and lipid bodies. Mol Biol Cell 2005 1.86
34 Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies. PLoS Biol 2008 1.85
35 Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells. EMBO J 2003 1.85
36 N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein. J Biol Chem 2001 1.84
37 Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. J Cell Biol 2010 1.84
38 Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites. J Cell Biol 2011 1.84
39 Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. Biochim Biophys Acta 2005 1.83
40 Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane. Mol Cell Biol 2006 1.81
41 Lipid droplet-organelle interactions; sharing the fats. Biochim Biophys Acta 2008 1.77
42 Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha. J Biol Chem 2004 1.70
43 Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis. Curr Opin Cell Biol 2010 1.70
44 A role for phosphatidic acid in the formation of "supersized" lipid droplets. PLoS Genet 2011 1.69
45 Dynamic microtubules regulate the local concentration of E-cadherin at cell-cell contacts. J Cell Sci 2006 1.68
46 Annexin A2-dependent polymerization of actin mediates endosome biogenesis. Dev Cell 2009 1.67
47 Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity. Curr Biol 2013 1.66
48 Lysobisphosphatidic acid controls endosomal cholesterol levels. J Biol Chem 2008 1.62
49 The GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway. Curr Biol 2008 1.62
50 Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant. Mol Biol Cell 2003 1.62
51 Cholesterol-sensitive Cdc42 activation regulates actin polymerization for endocytosis via the GEEC pathway. Traffic 2007 1.55
52 Inhibitors of COP-mediated transport and cholera toxin action inhibit simian virus 40 infection. Mol Biol Cell 2002 1.53
53 Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell. Diabetologia 2013 1.51
54 Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation. J Biol Chem 2002 1.51
55 Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking. PLoS One 2007 1.50
56 High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J Cell Biol 2011 1.49
57 A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking. J Cell Biol 2011 1.48
58 A single method for cryofixation and correlative light, electron microscopy and tomography of zebrafish embryos. Traffic 2008 1.48
59 Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis. Traffic 2006 1.48
60 Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites. J Cell Biol 2014 1.45
61 Caveolin, cholesterol, and lipid bodies. Semin Cell Dev Biol 2005 1.41
62 Caveolin regulates endocytosis of the muscle repair protein, dysferlin. J Biol Chem 2007 1.37
63 Electrostatic interactions positively regulate K-Ras nanocluster formation and function. Mol Cell Biol 2008 1.34
64 Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterning. Hum Mol Genet 2005 1.34
65 High-resolution 3D quantitative analysis of caveolar ultrastructure and caveola-cytoskeleton interactions. Traffic 2008 1.32
66 Observing cell surface signaling domains using electron microscopy. Sci STKE 2003 1.32
67 Caveolae at a glance. J Cell Sci 2010 1.31
68 Pore-forming toxins induce multiple cellular responses promoting survival. Cell Microbiol 2011 1.28
69 A novel hook-related protein family and the characterization of hook-related protein 1. Traffic 2005 1.27
70 Activation of the MAPK module from different spatial locations generates distinct system outputs. Mol Biol Cell 2008 1.25
71 Evolutionary analysis and molecular dissection of caveola biogenesis. J Cell Sci 2008 1.25
72 Epidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation. Mol Cell Biol 2010 1.25
73 Visualisation of macropinosome maturation by the recruitment of sorting nexins. J Cell Sci 2006 1.25
74 Expression of caveolin-1 enhances cholesterol efflux in hepatic cells. J Biol Chem 2004 1.24
75 Hydrophobic and basic domains target proteins to lipid droplets. Traffic 2009 1.22
76 Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane. J Biol Chem 2003 1.22
77 Arf6-independent GPI-anchored protein-enriched early endosomal compartments fuse with sorting endosomes via a Rab5/phosphatidylinositol-3'-kinase-dependent machinery. Mol Biol Cell 2006 1.21
78 The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading. Mol Biol Cell 2011 1.20
79 Quantitative analysis of lipid droplet fusion: inefficient steady state fusion but rapid stimulation by chemical fusogens. PLoS One 2010 1.19
80 Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission. J Biol Chem 2013 1.19
81 Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo. Hum Mol Genet 2006 1.19
82 EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization. Mol Biol Cell 2012 1.18
83 RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR. J Biol Chem 2004 1.17
84 Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins. J Biol Chem 2012 1.15
85 Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis. Traffic 2013 1.14
86 Characterization of Rab18, a lipid droplet-associated small GTPase. Methods Enzymol 2008 1.14
87 Aberrant dysferlin trafficking in cells lacking caveolin or expressing dystrophy mutants of caveolin-3. Hum Mol Genet 2005 1.14
88 Human Miltons associate with mitochondria and induce microtubule-dependent remodeling of mitochondrial networks. Biochim Biophys Acta 2010 1.14
89 Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains. J Cell Biol 2013 1.11
90 Rab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid droplets. PLoS Pathog 2013 1.10
91 Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling. J Cell Biol 2014 1.10
92 Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration. Mol Biol Cell 2004 1.08
93 Involvement of caveolin-2 in caveolar biogenesis in MDCK cells. FEBS Lett 2003 1.08
94 PTRF-cavin-1 expression decreases the migration of PC3 prostate cancer cells: role of matrix metalloprotease 9. Eur J Cell Biol 2010 1.07
95 Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. Gastroenterology 2008 1.07
96 Nucleophosmin and nucleolin regulate K-Ras plasma membrane interactions and MAPK signal transduction. J Biol Chem 2009 1.07
97 Redistribution of caveolae during mitosis. J Cell Sci 2011 1.05
98 Diversity of raft-like domains in late endosomes. PLoS One 2007 1.05
99 Ca2+-regulated pool of phosphatidylinositol-3-phosphate produced by phosphatidylinositol 3-kinase C2alpha on neurosecretory vesicles. Mol Biol Cell 2008 1.05
100 Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission. Mol Cell Biol 2012 1.04
101 Structure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions? Dev Cell 2012 1.04
102 Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation. J Cell Biol 2012 1.03
103 Uptake and intracellular fate of disulfide-bonded polymer hydrogel capsules for Doxorubicin delivery to colorectal cancer cells. ACS Nano 2010 1.03
104 Constitutive formation of caveolae in a bacterium. Cell 2012 1.03
105 Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages. J Leukoc Biol 2008 1.02
106 Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae. Elife 2013 1.01
107 Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies. Hum Mol Genet 2012 1.00
108 Caveolin-1 is required for lateral line neuromast and notochord development. J Cell Sci 2007 1.00
109 Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes. Mol Biol Cell 2011 0.98
110 Different characteristics and nucleotide binding properties of inosine monophosphate dehydrogenase (IMPDH) isoforms. PLoS One 2012 0.98
111 Postlipolytic insulin-dependent remodeling of micro lipid droplets in adipocytes. Mol Biol Cell 2012 0.98
112 Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters. Mol Cell Biol 2013 0.98
113 Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens. J Biol Chem 2014 0.97
114 Cytoskeletal tropomyosin Tm5NM1 is required for normal excitation-contraction coupling in skeletal muscle. Mol Biol Cell 2008 0.96
115 Alpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle. Hum Mol Genet 2010 0.96
116 Expression of PTRF in PC-3 Cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways. Mol Cell Proteomics 2011 0.95
117 Spatiotemporal regulation of early lipolytic signaling in adipocytes. J Biol Chem 2009 0.94
118 Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1. PLoS One 2012 0.94
119 Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: implications for liver regeneration. Hepatology 2012 0.92
120 Mathematical modeling of K-Ras nanocluster formation on the plasma membrane. Biophys J 2010 0.92
121 Quantitative proteomic analysis of the adipocyte plasma membrane. J Proteome Res 2011 0.91
122 Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3. J Biol Chem 2002 0.91
123 The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments. Mol Biol Cell 2012 0.91
124 Reduced plasma membrane expression of dysferlin mutants is attributed to accelerated endocytosis via a syntaxin-4-associated pathway. J Biol Chem 2010 0.90
125 Reassessing the role of phosphocaveolin-1 in cell adhesion and migration. Traffic 2007 0.90
126 PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis. Oncotarget 2013 0.89
127 Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2. Mol Cell Biol 2011 0.88
128 Modern approaches for ultrastructural analysis of the zebrafish embryo. Methods Cell Biol 2010 0.88
129 Caveolin-1 plays a critical role in the differentiation of monocytes into macrophages. Arterioscler Thromb Vasc Biol 2012 0.88
130 Regulation of albumin endocytosis by PSD95/Dlg/ZO-1 (PDZ) scaffolds. Interaction of Na+-H+ exchange regulatory factor-2 with ClC-5. J Biol Chem 2006 0.87
131 Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors. Chem Biol 2012 0.87
132 Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling. Cell Rep 2013 0.86
133 Role of SNX16 in the dynamics of tubulo-cisternal membrane domains of late endosomes. PLoS One 2011 0.86
134 Caveolin-1 deficiency leads to increased susceptibility to cell death and fibrosis in white adipose tissue: characterization of a lipodystrophic model. PLoS One 2012 0.86
135 Caveola-forming proteins caveolin-1 and PTRF in prostate cancer. Nat Rev Urol 2013 0.86
136 The trans-membrane protein p25 forms highly specialized domains that regulate membrane composition and dynamics. J Cell Sci 2003 0.86
137 Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy. Autophagy 2015 0.85
138 Patched1 is required in neural crest cells for the prevention of orofacial clefts. Hum Mol Genet 2013 0.85
139 Caveolins/caveolae protect adipocytes from fatty acid-mediated lipotoxicity. J Lipid Res 2011 0.83
140 SnapShot: caveolae, caveolins, and cavins. Cell 2013 0.82
141 Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation. Hum Mol Genet 2009 0.80
142 Characterisation of the adiponectin receptors: the non-conserved N-terminal region of AdipoR2 prevents its expression at the cell-surface. Biochem Biophys Res Commun 2013 0.80
143 Heterofibrins: inhibitors of lipid droplet formation from a deep-water southern Australian marine sponge, Spongia (Heterofibria) sp. Org Biomol Chem 2010 0.80
144 Characterization of Rab23, a negative regulator of sonic hedgehog signaling. Methods Enzymol 2005 0.80
145 Discreet and distinct clustering of five model membrane proteins revealed by single molecule localization microscopy. Mol Membr Biol 2015 0.79
146 Caveolae control the anti-inflammatory phenotype of senescent endothelial cells. Aging Cell 2014 0.79
147 Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers. Biophys J 2013 0.78
148 High-throughput screening of Australian marine organism extracts for bioactive molecules affecting the cellular storage of neutral lipids. PLoS One 2011 0.78
149 Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature 2016 0.77
150 SNX12 role in endosome membrane transport. PLoS One 2012 0.76
151 Correction: AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation. PLoS One 2016 0.75
152 The RhoD to centrosomal duplication. Small GTPases 2013 0.75