Published in Genet Med on February 01, 2011
Prioritizing genomic applications for action by level of evidence: a horizon-scanning method. Clin Pharmacol Ther (2014) 1.93
Horizon scanning for translational genomic research beyond bench to bedside. Genet Med (2014) 1.54
Knowledge integration at the center of genomic medicine. Genet Med (2012) 1.54
A population approach to precision medicine. Am J Prev Med (2012) 1.44
Building the evidence base for decision making in cancer genomic medicine using comparative effectiveness research. Genet Med (2012) 1.39
Improving the efficiency and relevance of evidence-based recommendations in the era of whole-genome sequencing: an EGAPP methods update. Genet Med (2012) 1.34
Multilevel research and the challenges of implementing genomic medicine. J Natl Cancer Inst Monogr (2012) 1.21
Beyond base pairs to bedside: a population perspective on how genomics can improve health. Am J Public Health (2011) 1.21
Prioritization in comparative effectiveness research: the CANCERGEN Experience. Med Care (2012) 1.17
Population sciences, translational research, and the opportunities and challenges for genomics to reduce the burden of cancer in the 21st century. Cancer Epidemiol Biomarkers Prev (2011) 1.13
Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits. Hum Hered (2015) 1.00
Comparative effectiveness research in cancer genomics and precision medicine: current landscape and future prospects. J Natl Cancer Inst (2013) 0.98
Crowd-funded micro-grants for genomics and "big data": an actionable idea connecting small (artisan) science, infrastructure science, and citizen philanthropy. OMICS (2013) 0.92
Genomic Analysis as the First Step toward Personalized Treatment in Renal Cell Carcinoma. Front Oncol (2014) 0.85
Looking back at genomic medicine in 2011. Genome Med (2012) 0.79
Use of genomic panels to determine risk of developing type 2 diabetes in the general population: a targeted evidence-based review. Genet Med (2013) 0.79
How the electronic health record will change the future of health care. Yale J Biol Med (2012) 0.79
Rethinking our public health genetics research paradigm. Am J Public Health (2013) 0.78
Genomics in Public Health: Perspective from the Office of Public Health Genomics at the Centers for Disease Control and Prevention (CDC). Healthcare (Basel) (2015) 0.78
Getting our priorities straight: a novel framework for stakeholder-informed prioritization of cancer genomics research. Genet Med (2012) 0.78
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science (2009) 10.78
Regulation of cellular metabolism by protein lysine acetylation. Science (2010) 10.55
Letting the genome out of the bottle--will we get our wish? N Engl J Med (2008) 9.10
Deploying whole genome sequencing in clinical practice and public health: meeting the challenge one bin at a time. Genet Med (2011) 8.48
Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases. Am J Epidemiol (2006) 7.66
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet (2008) 6.71
A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell (2006) 6.15
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. Cell (2007) 5.84
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell (2010) 5.73
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working Group. Genet Med (2009) 5.69
Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer. J Clin Oncol (2013) 5.21
A navigator for human genome epidemiology. Nat Genet (2008) 5.07
Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol (2007) 4.96
Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology. Int J Epidemiol (2008) 4.53
How many genes underlie the occurrence of common complex diseases in the population? Int J Epidemiol (2005) 4.46
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27
Sodium and potassium intake and mortality among US adults: prospective data from the Third National Health and Nutrition Examination Survey. Arch Intern Med (2011) 4.22
Effectiveness of interventions to increase screening for breast, cervical, and colorectal cancers: nine updated systematic reviews for the guide to community preventive services. Am J Prev Med (2012) 4.07
Can family history be used as a tool for public health and preventive medicine? Genet Med (2002) 3.76
National Institutes of Health approaches to dissemination and implementation science: current and future directions. Am J Public Health (2012) 3.72
EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome. Genet Med (2009) 3.57
Development and validation of a CGH microarray for clinical cytogenetic diagnosis. Genet Med (2005) 3.39
A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions. Am J Hum Genet (2008) 3.25
Recommendations for returning genomic incidental findings? We need to talk! Genet Med (2013) 3.23
A road map for efficient and reliable human genome epidemiology. Nat Genet (2006) 3.21
Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancer. J Clin Oncol (2010) 3.06
Client-directed interventions to increase community demand for breast, cervical, and colorectal cancer screening a systematic review. Am J Prev Med (2008) 3.05
What is the clinical utility of genetic testing? Genet Med (2006) 3.01
Assessing adiposity: a scientific statement from the American Heart Association. Circulation (2011) 3.00
Research priorities for evaluating family history in the prevention of common chronic diseases. Am J Prev Med (2003) 2.99
Improving validation practices in "omics" research. Science (2011) 2.73
Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. Proc Natl Acad Sci U S A (2004) 2.66
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome. Mol Cell (2012) 2.54
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. Science (2013) 2.49
Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. J Clin Epidemiol (2009) 2.45
Family history in public health practice: a genomic tool for disease prevention and health promotion. Annu Rev Public Health (2010) 2.43
STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement. PLoS Med (2009) 2.39
Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells. Nat Cell Biol (2006) 2.39
The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases. Genet Med (2007) 2.34
Tracking the epidemiology of human genes in the literature: the HuGE Published Literature database. Am J Epidemiol (2006) 2.34
Epithelial polarity and tubulogenesis in vitro. Trends Cell Biol (2003) 2.31
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell (2011) 2.29
Most published research findings are false-but a little replication goes a long way. PLoS Med (2007) 2.26
Family history and prevalence of diabetes in the U.S. population: the 6-year results from the National Health and Nutrition Examination Survey (1999-2004). Diabetes Care (2007) 2.22
Developing Family Healthware, a family history screening tool to prevent common chronic diseases. Prev Chronic Dis (2008) 2.20
Health care provider and consumer awareness, perceptions, and use of direct-to-consumer personal genomic tests, United States, 2008. Genet Med (2009) 2.17
DNA banking for epidemiologic studies: a review of current practices. Epidemiology (2002) 2.16
The path from genome-based research to population health: development of an international public health genomics network. Genet Med (2006) 2.15
Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases. Am J Epidemiol (2009) 2.15
Invited commentary: genes, environment, and hybrid vigor. Am J Epidemiol (2009) 2.15
Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis. Curr Biol (2008) 2.13
Intervention to increase recommendation and delivery of screening for breast, cervical, and colorectal cancers by healthcare providers a systematic review of provider reminders. Am J Prev Med (2010) 2.12
Genomic profiling to promote a healthy lifestyle: not ready for prime time. Nat Genet (2003) 2.11
Evolution of the "drivers" of translational cancer epidemiology: analysis of funded grants and the literature. Am J Epidemiol (2015) 2.04
Client-directed interventions to increase community access to breast, cervical, and colorectal cancer screening a systematic review. Am J Prev Med (2008) 2.01
Future health applications of genomics: priorities for communication, behavioral, and social sciences research. Am J Prev Med (2010) 1.98
The associations between race and geographic area and quality-of-care indicators in patients approaching ESRD. Clin J Am Soc Nephrol (2013) 1.87
Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes. Am J Hum Genet (2003) 1.85
Genomics and the prevention and control of common chronic diseases: emerging priorities for public health action. Prev Chronic Dis (2005) 1.84
Required sample size and nonreplicability thresholds for heterogeneous genetic associations. Proc Natl Acad Sci U S A (2008) 1.84
On the use of population attributable fraction to determine sample size for case-control studies of gene-environment interaction. Epidemiology (2003) 1.82
STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement. Eur J Clin Invest (2009) 1.82
Awareness and utilization of BRCA1/2 testing among U.S. primary care physicians. Am J Prev Med (2011) 1.80
The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis. BMC Genomics (2011) 1.79
From public health emergency to public health service: the implications of evolving criteria for newborn screening panels. Pediatrics (2006) 1.77
Population-based study of the prevalence of family history of cancer: implications for cancer screening and prevention. Genet Med (2006) 1.77
GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique. BMC Bioinformatics (2008) 1.75
The next generation of large-scale epidemiologic research: implications for training cancer epidemiologists. Am J Epidemiol (2014) 1.73
"Drivers" of translational cancer epidemiology in the 21st century: needs and opportunities. Cancer Epidemiol Biomarkers Prev (2013) 1.72
Association between 9p21 genomic markers and heart disease: a meta-analysis. JAMA (2010) 1.71
Cancer GAMAdb: database of cancer genetic associations from meta-analyses and genome-wide association studies. Eur J Hum Genet (2011) 1.69
Impact of violations and deviations in Hardy-Weinberg equilibrium on postulated gene-disease associations. Am J Epidemiol (2006) 1.67
Family history of type 2 diabetes: a population-based screening tool for prevention? Genet Med (2006) 1.67
Application of support vector machine modeling for prediction of common diseases: the case of diabetes and pre-diabetes. BMC Med Inform Decis Mak (2010) 1.66
Managed care, hospice use, site of death, and medical expenditures in the last year of life. Arch Intern Med (2002) 1.65
Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature. J Bone Miner Res (2012) 1.63
Challenges of translating genetic tests into clinical and public health practice. Nat Rev Genet (2009) 1.62
The emergence of networks in human genome epidemiology: challenges and opportunities. Epidemiology (2007) 1.61
Morphological and biochemical analysis of Rac1 in three-dimensional epithelial cell cultures. Methods Enzymol (2006) 1.59
Age structure changes and extraordinary lifespan in wild medfly populations. Aging Cell (2008) 1.57
Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets. J Biol Chem (2005) 1.56
Knowledge integration at the center of genomic medicine. Genet Med (2012) 1.54
Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994. Am J Epidemiol (2008) 1.53
Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review. Genet Med (2009) 1.49
Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement. Hum Genet (2009) 1.47
Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein. J Cell Biol (2004) 1.47
Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration. J Clin Epidemiol (2011) 1.46
Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res (2013) 1.46
A network of investigator networks in human genome epidemiology. Am J Epidemiol (2005) 1.43
Does genetic testing really improve the prediction of future type 2 diabetes? PLoS Med (2006) 1.43
Polarity proteins PAR6 and aPKC regulate cell death through GSK-3beta in 3D epithelial morphogenesis. J Cell Sci (2007) 1.42
Building the evidence base for decision making in cancer genomic medicine using comparative effectiveness research. Genet Med (2012) 1.39
Identification of direct serum-response factor gene targets during Me2SO-induced P19 cardiac cell differentiation. J Biol Chem (2005) 1.38
Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet (2012) 1.38