Published in J Biol Chem on May 31, 2005
Defining the mammalian CArGome. Genome Res (2005) 2.59
Defining the transcriptional redundancy of early bodywall muscle development in C. elegans: evidence for a unified theory of animal muscle development. Genes Dev (2006) 2.33
SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nat Cell Biol (2008) 1.83
Re-employment of developmental transcription factors in adult heart disease. Semin Cell Dev Biol (2006) 1.82
Serum response factor micromanaging cardiogenesis. Curr Opin Cell Biol (2007) 1.77
Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation. Proc Natl Acad Sci U S A (2005) 1.72
The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs. PLoS Genet (2011) 1.69
Effect of destrin mutations on the gene expression profile in vivo. Physiol Genomics (2008) 1.68
UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program. Dev Cell (2011) 1.66
Selective repression of MEF2 activity by PKA-dependent proteolysis of HDAC4. J Cell Biol (2011) 1.42
Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. Proc Natl Acad Sci U S A (2008) 1.39
Mef2s are required for thick filament formation in nascent muscle fibres. Development (2007) 1.37
Myocardin sumoylation transactivates cardiogenic genes in pluripotent 10T1/2 fibroblasts. Mol Cell Biol (2006) 1.20
Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development. Development (2010) 1.17
Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages. Mol Cell Biol (2010) 1.15
Myocardin regulates BMP10 expression and is required for heart development. J Clin Invest (2012) 1.10
Regulation of survival in adult hippocampal and glioblastoma stem cell lineages by the homeodomain-only protein HOP. Neural Dev (2008) 1.05
SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin. Nucleic Acids Res (2009) 1.03
Protein tyrosine phosphatase-like A regulates myoblast proliferation and differentiation through MyoG and the cell cycling signaling pathway. Mol Cell Biol (2011) 0.95
Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction. Dis Model Mech (2012) 0.91
Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice. Hepatology (2009) 0.88
Enhancer of polycomb1 acts on serum response factor to regulate skeletal muscle differentiation. J Biol Chem (2009) 0.87
Formin homology domain-containing protein 1 regulates smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol (2010) 0.86
Cardiac expression of ms1/STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4. Mol Cell Biol (2012) 0.85
Regulation of serum response factor activity and smooth muscle cell apoptosis by chromodomain helicase DNA-binding protein 8. Am J Physiol Cell Physiol (2010) 0.85
STARS is essential to maintain cardiac development and function in vivo via a SRF pathway. PLoS One (2012) 0.83
Serum response factor modulates neuron survival during peripheral axon injury. J Neuroinflammation (2012) 0.82
The STARS signaling pathway: a key regulator of skeletal muscle function. Pflugers Arch (2014) 0.81
Serum Response Factor in Muscle Tissues: From Development to Ageing. Eur J Transl Myol (2016) 0.80
Loss of serum response factor induces microRNA-mediated apoptosis in intestinal smooth muscle cells. Cell Death Dis (2015) 0.80
Serum Response Factor Is Essential for Prenatal Gastrointestinal Smooth Muscle Development and Maintenance of Differentiated Phenotype. J Neurogastroenterol Motil (2015) 0.80
Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis. Hum Mol Genet (2014) 0.80
The functional diversity of essential genes required for mammalian cardiac development. Genesis (2014) 0.79
Caspase-3 knock-down reverses contractile dysfunction induced by sepsis in adult rat ventricular myocytes. Br J Pharmacol (2010) 0.78
Serum response factor: positive and negative regulation of an epithelial gene expression network in the destrin mutant cornea. Physiol Genomics (2014) 0.78
An intragenic SRF-dependent regulatory motif directs cardiac-specific microRNA-1-1/133a-2 expression. PLoS One (2013) 0.78
Serum response factor is required for cell contact maintenance but dispensable for proliferation in visceral yolk sac endothelium. BMC Dev Biol (2011) 0.78
Myocardin-related transcription factors are required for cardiac development and function. Dev Biol (2015) 0.77
Partnering up for cardiac hypertrophy. Circ Res (2006) 0.77
Characteristics of the CArG-SRF binding context in mammalian genomes. Mamm Genome (2009) 0.76
Histone Deacetylase 3 Coordinates Deacetylase-independent Epigenetic Silencing of Transforming Growth Factor-β1 (TGF-β1) to Orchestrate Second Heart Field Development. J Biol Chem (2015) 0.76
Motile cilia harbor serum response factor as a mechanism of environment sensing and injury response in the airway. Am J Physiol Lung Cell Mol Physiol (2014) 0.76
Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.76
Multi-phenotypic Role of Serum Response Factor in the Gastrointestinal System. J Neurogastroenterol Motil (2016) 0.75
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell (2005) 21.01
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell (2007) 12.72
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science (2009) 10.78
Regulation of cellular metabolism by protein lysine acetylation. Science (2010) 10.55
Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A (2003) 7.87
A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell (2006) 6.15
A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy. Cell (2007) 5.85
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. Cell (2007) 5.84
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell (2010) 5.73
Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer. J Clin Oncol (2013) 5.21
A navigator for human genome epidemiology. Nat Genet (2008) 5.07
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature (2004) 4.76
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell (2008) 4.70
Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability. Circ Res (2006) 4.41
Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization. Nature (2006) 4.35
Unchain my heart: the scientific foundations of cardiac repair. J Clin Invest (2005) 4.25
Linking actin dynamics and gene transcription to drive cellular motile functions. Nat Rev Mol Cell Biol (2010) 4.12
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A (2008) 4.00
Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proc Natl Acad Sci U S A (2002) 3.74
Sizing up the heart: development redux in disease. Genes Dev (2003) 3.52
Development and validation of a CGH microarray for clinical cytogenetic diagnosis. Genet Med (2005) 3.39
Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice. Proc Natl Acad Sci U S A (2005) 3.30
Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy. J Clin Invest (2006) 3.22
Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancer. J Clin Oncol (2010) 3.06
Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3. Proc Natl Acad Sci U S A (2002) 2.99
NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart. Proc Natl Acad Sci U S A (2010) 2.95
Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor. Circulation (2007) 2.93
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning. Development (2005) 2.92
WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy. Oncogene (2004) 2.86
Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy. Nat Med (2002) 2.82
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome. Nature (2009) 2.74
Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. Proc Natl Acad Sci U S A (2004) 2.66
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function. Nat Immunol (2006) 2.65
Multiple roles for Sox2 in the developing and adult mouse trachea. Development (2009) 2.62
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract. Development (2004) 2.62
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nat Med (2004) 2.61
The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development (2004) 2.61
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome. Mol Cell (2012) 2.54
Hop is an unusual homeobox gene that modulates cardiac development. Cell (2002) 2.52
SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Mol Cell (2010) 2.52
BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development (2004) 2.50
Morphogenesis of the right ventricle requires myocardial expression of Gata4. J Clin Invest (2005) 2.50
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. Science (2013) 2.49
Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury. Circ Res (2004) 2.45
Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis. Mol Genet Metab (2003) 2.42
Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells. Nat Cell Biol (2006) 2.39
Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size. Sci Signal (2011) 2.38
Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A. J Clin Invest (2003) 2.37
Tracking the epidemiology of human genes in the literature: the HuGE Published Literature database. Am J Epidemiol (2006) 2.34
Epithelial polarity and tubulogenesis in vitro. Trends Cell Biol (2003) 2.31
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell (2011) 2.29
Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors. Dev Cell (2003) 2.28
A Wnt- and beta -catenin-dependent pathway for mammalian cardiac myogenesis. Proc Natl Acad Sci U S A (2003) 2.28
Essential role of TAK1 in thymocyte development and activation. Proc Natl Acad Sci U S A (2006) 2.19
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF. Mol Cell (2004) 2.19
Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases. Am J Epidemiol (2009) 2.15
Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis. Curr Biol (2008) 2.13
Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling. Circ Res (2006) 2.08
Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity. Proc Natl Acad Sci U S A (2004) 2.07
Lineage and morphogenetic analysis of the cardiac valves. Circ Res (2004) 2.06
Fgf8 is required for anterior heart field development. Development (2006) 2.03
A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc Natl Acad Sci U S A (2006) 2.03
COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development (2005) 2.00
Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells. J Cell Biol (2002) 1.99
Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis. FASEB J (2006) 1.99
The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. J Clin Invest (2010) 1.98
Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling. Proc Natl Acad Sci U S A (2004) 1.93
The associations between race and geographic area and quality-of-care indicators in patients approaching ESRD. Clin J Am Soc Nephrol (2013) 1.87
A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration. Cell (2013) 1.86
Cardiac muscle regeneration: lessons from development. Genes Dev (2011) 1.86
Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL-positive leukemias identified by a proteomics approach. Blood (2006) 1.85
Bartonella adhesin a mediates a proangiogenic host cell response. J Exp Med (2004) 1.84
Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs. Circ Res (2008) 1.83
A role in learning for SRF: deletion in the adult forebrain disrupts LTD and the formation of an immediate memory of a novel context. Neuron (2006) 1.83
An exocyst complex functions in plant cell growth in Arabidopsis and tobacco. Plant Cell (2008) 1.81
MEF2 activates a genetic program promoting chamber dilation and contractile dysfunction in calcineurin-induced heart failure. Circulation (2006) 1.80
Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells. Ann N Y Acad Sci (2004) 1.80
Comparative proteome analysis of Staphylococcus aureus biofilm and planktonic cells and correlation with transcriptome profiling. Proteomics (2006) 1.79
The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis. BMC Genomics (2011) 1.79
Serum response factor micromanaging cardiogenesis. Curr Opin Cell Biol (2007) 1.77
Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis. Proc Natl Acad Sci U S A (2006) 1.76
TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways. J Clin Invest (2007) 1.75
Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3zeta. Genes Dev (2010) 1.75
Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells. Proc Natl Acad Sci U S A (2007) 1.75
Concurrent partnerships, nonmonogamous partners, and substance use among women in the United States. Am J Public Health (2010) 1.75
Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. Proc Natl Acad Sci U S A (2012) 1.72
Cardiomyocyte-restricted deletion of connexin43 during mouse development. J Mol Cell Cardiol (2006) 1.70
Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy. FEBS Lett (2007) 1.69
Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolic acidification during ischemia, and reduces ischemia/reperfusion injury. Circ Res (2004) 1.69
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart. Dev Biol (2005) 1.69
Cancer GAMAdb: database of cancer genetic associations from meta-analyses and genome-wide association studies. Eur J Hum Genet (2011) 1.69
Proteogenomics of Pristionchus pacificus reveals distinct proteome structure of nematode models. Genome Res (2010) 1.66
Managed care, hospice use, site of death, and medical expenditures in the last year of life. Arch Intern Med (2002) 1.65
Neuronal migration in the murine rostral migratory stream requires serum response factor. Proc Natl Acad Sci U S A (2005) 1.64