| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin.
|
Nature
|
2002
|
4.03
|
|
2
|
Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle.
|
Science
|
2002
|
3.68
|
|
3
|
Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase.
|
J Biol Chem
|
2010
|
3.45
|
|
4
|
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway.
|
J Cell Biol
|
2005
|
2.97
|
|
5
|
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast.
|
J Cell Biol
|
2008
|
2.85
|
|
6
|
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking.
|
Nature
|
2004
|
2.81
|
|
7
|
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.
|
J Clin Invest
|
2011
|
2.68
|
|
8
|
Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides.
|
J Virol
|
2008
|
2.43
|
|
9
|
Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice.
|
Neuron
|
2002
|
2.21
|
|
10
|
Chondroitin fragments are odorants that trigger fear behavior in fish.
|
Curr Biol
|
2012
|
2.20
|
|
11
|
ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma.
|
J Cell Biol
|
2003
|
2.19
|
|
12
|
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology.
|
Mol Biol Cell
|
2009
|
2.17
|
|
13
|
Salmonella modulates vesicular traffic by altering phosphoinositide metabolism.
|
Science
|
2004
|
2.06
|
|
14
|
Inhibitory effect of dietary lipids on chaperone-mediated autophagy.
|
Proc Natl Acad Sci U S A
|
2012
|
1.97
|
|
15
|
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.
|
Immunity
|
2012
|
1.96
|
|
16
|
Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses.
|
Proc Natl Acad Sci U S A
|
2004
|
1.84
|
|
17
|
A role for phosphatidic acid in the formation of "supersized" lipid droplets.
|
PLoS Genet
|
2011
|
1.69
|
|
18
|
Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism.
|
Science
|
2010
|
1.64
|
|
19
|
Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome.
|
Curr Biol
|
2009
|
1.62
|
|
20
|
Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer.
|
Nature
|
2014
|
1.60
|
|
21
|
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.
|
PLoS Biol
|
2011
|
1.56
|
|
22
|
The phospholipase D1 pathway modulates macroautophagy.
|
Nat Commun
|
2010
|
1.56
|
|
23
|
Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome.
|
Proc Natl Acad Sci U S A
|
2008
|
1.54
|
|
24
|
Comparative lipidomic analysis of mouse and human brain with Alzheimer disease.
|
J Biol Chem
|
2011
|
1.51
|
|
25
|
Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits.
|
J Neurosci
|
2010
|
1.49
|
|
26
|
Sensitive profiling of chemically diverse bioactive lipids.
|
J Lipid Res
|
2007
|
1.45
|
|
27
|
Arabidopsis lipins mediate eukaryotic pathway of lipid metabolism and cope critically with phosphate starvation.
|
Proc Natl Acad Sci U S A
|
2009
|
1.44
|
|
28
|
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity.
|
J Cell Biol
|
2012
|
1.41
|
|
29
|
The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis.
|
J Cell Biol
|
2008
|
1.32
|
|
30
|
Mass spectrometry-based profiling of phospholipids and sphingolipids in extracts from Saccharomyces cerevisiae.
|
Yeast
|
2006
|
1.30
|
|
31
|
Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation.
|
PLoS Genet
|
2011
|
1.30
|
|
32
|
Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles.
|
Proc Natl Acad Sci U S A
|
2003
|
1.28
|
|
33
|
Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics.
|
Mol Biosyst
|
2010
|
1.28
|
|
34
|
Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin.
|
J Bacteriol
|
2009
|
1.25
|
|
35
|
Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin).
|
J Biol Chem
|
2012
|
1.19
|
|
36
|
Meibum lipid composition in Asians with dry eye disease.
|
PLoS One
|
2011
|
1.16
|
|
37
|
A small molecule fusion inhibitor of dengue virus.
|
Antiviral Res
|
2009
|
1.16
|
|
38
|
Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis.
|
J Lipid Res
|
2011
|
1.14
|
|
39
|
Comparative plasma lipidome between human and cynomolgus monkey: are plasma polar lipids good biomarkers for diabetic monkeys?
|
PLoS One
|
2011
|
1.14
|
|
40
|
Non-targeted profiling of lipids during kainate-induced neuronal injury.
|
FASEB J
|
2006
|
1.13
|
|
41
|
Yeast lipid analysis and quantification by mass spectrometry.
|
Methods Enzymol
|
2010
|
1.13
|
|
42
|
Membrane lipids as signaling molecules.
|
Curr Opin Lipidol
|
2007
|
1.12
|
|
43
|
Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.
|
Mol Biol Cell
|
2008
|
1.10
|
|
44
|
Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling.
|
J Cell Biol
|
2014
|
1.10
|
|
45
|
Towards ontology-driven navigation of the lipid bibliosphere.
|
BMC Bioinformatics
|
2008
|
1.10
|
|
46
|
Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities.
|
J Am Chem Soc
|
2010
|
1.09
|
|
47
|
The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway.
|
Mol Biol Cell
|
2003
|
1.08
|
|
48
|
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion.
|
PLoS Pathog
|
2013
|
1.05
|
|
49
|
Fenretinide prevents lipid-induced insulin resistance by blocking ceramide biosynthesis.
|
J Biol Chem
|
2012
|
1.05
|
|
50
|
U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication.
|
Antiviral Res
|
2011
|
1.04
|
|
51
|
Extensive characterization of human tear fluid collected using different techniques unravels the presence of novel lipid amphiphiles.
|
J Lipid Res
|
2013
|
1.03
|
|
52
|
Emodin inhibits tumor cell adhesion through disruption of the membrane lipid Raft-associated integrin signaling pathway.
|
Cancer Res
|
2006
|
1.03
|
|
53
|
XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis.
|
J Immunol
|
2009
|
1.02
|
|
54
|
Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans.
|
Proc Natl Acad Sci U S A
|
2013
|
1.02
|
|
55
|
Biochemical membrane lipidomics during Drosophila development.
|
Dev Cell
|
2012
|
1.02
|
|
56
|
Structural and biological diversity of lipopolysaccharides from Burkholderia pseudomallei and Burkholderia thailandensis.
|
Clin Vaccine Immunol
|
2009
|
1.01
|
|
57
|
Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids.
|
Nat Med
|
2012
|
1.00
|
|
58
|
A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila.
|
Autophagy
|
2009
|
1.00
|
|
59
|
PGC-1α improves glucose homeostasis in skeletal muscle in an activity-dependent manner.
|
Diabetes
|
2012
|
0.99
|
|
60
|
Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice.
|
EMBO Mol Med
|
2011
|
0.99
|
|
61
|
Derivatization-independent cholesterol analysis in crude lipid extracts by liquid chromatography/mass spectrometry: applications to a rabbit model for atherosclerosis.
|
J Chromatogr A
|
2011
|
0.99
|
|
62
|
Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay.
|
PLoS One
|
2010
|
0.98
|
|
63
|
The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network.
|
Mol Cell
|
2012
|
0.97
|
|
64
|
Lipid droplet-associated proteins are involved in the biosynthesis and hydrolysis of triacylglycerol in Mycobacterium bovis bacillus Calmette-Guerin.
|
J Biol Chem
|
2010
|
0.96
|
|
65
|
Lipid pathway alterations in Parkinson's disease primary visual cortex.
|
PLoS One
|
2011
|
0.96
|
|
66
|
Cdk5/p25-induced cytosolic PLA2-mediated lysophosphatidylcholine production regulates neuroinflammation and triggers neurodegeneration.
|
J Neurosci
|
2012
|
0.95
|
|
67
|
Peculiarities of host cholesterol transport to the unique intracellular vacuole containing Toxoplasma.
|
Traffic
|
2005
|
0.95
|
|
68
|
Caspase-dependent and -independent lipotoxic cell-death pathways in fission yeast.
|
J Cell Sci
|
2008
|
0.92
|
|
69
|
Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo.
|
J Neurosci
|
2013
|
0.92
|
|
70
|
N-Octanoylhomoserine lactone signalling mediated by the BpsI-BpsR quorum sensing system plays a major role in biofilm formation of Burkholderia pseudomallei.
|
Microbiology
|
2011
|
0.91
|
|
71
|
Rapid and sensitive profiling of tear wax ester species using high performance liquid chromatography coupled with tandem mass spectrometry.
|
J Chromatogr A
|
2013
|
0.91
|
|
72
|
Mitochondrial changes in ageing Caenorhabditis elegans--what do we learn from superoxide dismutase knockouts?
|
PLoS One
|
2011
|
0.90
|
|
73
|
The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation.
|
J Biol Chem
|
2012
|
0.89
|
|
74
|
APOE genotype results in differential effects on the peripheral clearance of amyloid-beta42 in APOE knock-in and knock-out mice.
|
J Alzheimers Dis
|
2010
|
0.88
|
|
75
|
Evidence that selective changes in the lipid composition of raft-membranes occur during respiratory syncytial virus infection.
|
Virology
|
2009
|
0.87
|
|
76
|
A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance.
|
Metab Eng
|
2011
|
0.87
|
|
77
|
Transcriptomic and lipidomic profiles of glycerolipids during Arabidopsis flower development.
|
New Phytol
|
2014
|
0.85
|
|
78
|
Implications for lipids during replication of enveloped viruses.
|
Chem Phys Lipids
|
2010
|
0.85
|
|
79
|
Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids?
|
Int J Neuropsychopharmacol
|
2009
|
0.85
|
|
80
|
Docosapentaenoic acid (DPA) is a critical determinant of cubic membrane formation in amoeba Chaos mitochondria.
|
FASEB J
|
2009
|
0.85
|
|
81
|
Ablation of dihydroceramide desaturase confers resistance to etoposide-induced apoptosis in vitro.
|
PLoS One
|
2012
|
0.85
|
|
82
|
Lipidomic analysis of human tear fluid reveals structure-specific lipid alterations in dry eye syndrome.
|
J Lipid Res
|
2013
|
0.84
|
|
83
|
A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis.
|
PLoS Genet
|
2011
|
0.84
|
|
84
|
InsP3-mediated intracellular calcium signalling is altered by expression of synaptojanin-1.
|
Biochem J
|
2004
|
0.83
|
|
85
|
Sialic acid linkage in glycosphingolipids is a molecular correlate for trafficking and delivery of extracellular cargo.
|
Traffic
|
2013
|
0.82
|
|
86
|
Profiling brain and plasma lipids in human APOE epsilon2, epsilon3, and epsilon4 knock-in mice using electrospray ionization mass spectrometry.
|
J Alzheimers Dis
|
2010
|
0.82
|
|
87
|
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction.
|
Biochimie
|
2012
|
0.82
|
|
88
|
Click-based synthesis and proteomic profiling of lipstatin analogues.
|
Chem Commun (Camb)
|
2010
|
0.82
|
|
89
|
Lipidomic "deep profiling": an enhanced workflow to reveal new molecular species of signaling lipids.
|
Anal Chem
|
2014
|
0.81
|
|
90
|
The size and phospholipid composition of lipid droplets can influence their proteome.
|
Biochem Biophys Res Commun
|
2011
|
0.81
|
|
91
|
Identification and characterization of the lipid-binding property of GrlR, a locus of enterocyte effacement regulator.
|
Biochem J
|
2009
|
0.80
|
|
92
|
LipidGO: database for lipid-related GO terms and applications.
|
Bioinformatics
|
2013
|
0.80
|
|
93
|
Lipidomics and genomics of Mycobacterium tuberculosis reveal lineage-specific trends in mycolic acid biosynthesis.
|
Microbiologyopen
|
2014
|
0.80
|
|
94
|
The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1.
|
J Cell Biol
|
2015
|
0.80
|
|
95
|
Lipidomic study of intracellular Singapore grouper iridovirus.
|
Virology
|
2010
|
0.80
|
|
96
|
Neonatal overnutrition in mice exacerbates high-fat diet-induced metabolic perturbations.
|
J Endocrinol
|
2013
|
0.80
|
|
97
|
Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice.
|
Neurobiol Aging
|
2013
|
0.79
|
|
98
|
Targeting lipid esterases in mycobacteria grown under different physiological conditions using activity-based profiling with tetrahydrolipstatin (THL).
|
Mol Cell Proteomics
|
2013
|
0.79
|
|
99
|
Expression, activity, and role of serine palmitoyltransferase in the rat hippocampus after kainate injury.
|
J Neurosci Res
|
2007
|
0.79
|
|
100
|
The identification of antioxidants in dark soy sauce.
|
Free Radic Res
|
2007
|
0.79
|
|
101
|
Abc3-mediated efflux of an endogenous digoxin-like steroidal glycoside by Magnaporthe oryzae is necessary for host invasion during blast disease.
|
PLoS Pathog
|
2012
|
0.79
|
|
102
|
SNX3-dependent regulation of epidermal growth factor receptor (EGFR) trafficking and degradation by aspirin in epidermoid carcinoma (A-431) cells.
|
Cell Mol Life Sci
|
2011
|
0.78
|
|
103
|
Biochemistry of inositol lipids.
|
Front Biosci
|
2008
|
0.78
|
|
104
|
Novel phage display-derived mycolic acid-specific antibodies with potential for tuberculosis diagnosis.
|
J Lipid Res
|
2013
|
0.78
|
|
105
|
Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack.
|
J Lipid Res
|
2014
|
0.78
|
|
106
|
Generation and characterization of a novel recombinant antibody against 15-ketocholestane isolated by phage-display.
|
Int J Mol Sci
|
2012
|
0.77
|
|
107
|
Lipid anti-lipid antibody responses correlate with disease activity in systemic lupus erythematosus.
|
PLoS One
|
2013
|
0.77
|
|
108
|
Role of prefrontal cortical calcium independent phospholipase A₂ in antidepressant-like effect of maprotiline.
|
Int J Neuropsychopharmacol
|
2011
|
0.76
|
|
109
|
Phosphatidic acid is a major phospholipid class in reproductive organs of Arabidopsis thaliana.
|
Plant Signal Behav
|
2015
|
0.76
|
|
110
|
Mining to find the lipid interaction networks involved in Ovarian Cancers.
|
Summit on Translat Bioinforma
|
2009
|
0.76
|
|
111
|
Distribution of secretory phospholipase A2 XIIA in the brain and its role in lipid metabolism and cognition.
|
Mol Neurobiol
|
2014
|
0.76
|
|
112
|
Neutral not a loss: phosphoinositides beyond the head group.
|
Nat Methods
|
2011
|
0.75
|
|
113
|
Targeted and non-targeted analysis of membrane lipids using mass spectrometry.
|
Methods Cell Biol
|
2012
|
0.75
|