Published in Proc Natl Acad Sci U S A on January 24, 2011
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26
Vti1a identifies a vesicle pool that preferentially recycles at rest and maintains spontaneous neurotransmission. Neuron (2012) 2.08
Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. Nat Commun (2014) 1.06
Both pre- and postsynaptic activity of Nsf prevents degeneration of hair-cell synapses. PLoS One (2011) 0.91
Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes. J Biol Chem (2012) 0.88
Molecular underpinnings of synaptic vesicle pool heterogeneity. Traffic (2015) 0.85
Molecular characterization and functional significance of the Vti family of SNARE proteins in tick salivary glands. Insect Biochem Mol Biol (2013) 0.81
Transforming growth factor beta receptor 1 is increased following abstinence from cocaine self-administration, but not cocaine sensitization. PLoS One (2013) 0.80
Defects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function. Front Neurosci (2015) 0.80
The SNARE protein vti1a functions in dense-core vesicle biogenesis. EMBO J (2014) 0.77
Selective molecular impairment of spontaneous neurotransmission modulates synaptic efficacy. Nat Commun (2017) 0.75
SNAREs--engines for membrane fusion. Nat Rev Mol Cell Biol (2006) 12.74
The mechanisms of vesicle budding and fusion. Cell (2004) 7.96
Endocytosis and intracellular trafficking of ErbBs. Exp Cell Res (2009) 3.70
Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. J Cell Biol (2002) 3.36
The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network. Dev Cell (2007) 3.00
Functions and mechanisms of retrograde neurotrophin signalling. Nat Rev Neurosci (2005) 2.78
The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p. J Cell Biol (1997) 2.50
A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO J (2000) 2.30
Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron (1995) 2.27
Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. J Biol Chem (2004) 2.17
The Saccharomyces cerevisiae v-SNARE Vti1p is required for multiple membrane transport pathways to the vacuole. Mol Biol Cell (1999) 2.13
An elaborate classification of SNARE proteins sheds light on the conservation of the eukaryotic endomembrane system. Mol Biol Cell (2007) 1.89
A dual mechanism controlling the localization and function of exocytic v-SNAREs. Proc Natl Acad Sci U S A (2003) 1.86
Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth. J Cell Biol (2000) 1.82
Absence of sensory neurons before target innervation in brain-derived neurotrophic factor-, neurotrophin 3-, and TrkC-deficient embryonic mice. J Neurosci (1997) 1.70
Three novel proteins of the syntaxin/SNAP-25 family. J Biol Chem (1998) 1.67
A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells. J Cell Biol (2008) 1.63
Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO Rep (2004) 1.62
Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes. J Cell Sci (2006) 1.59
Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes. Mol Biol Cell (2010) 1.55
The SNAREs vti1a and vti1b have distinct localization and SNARE complex partners. Eur J Cell Biol (2002) 1.52
Pincher-mediated macroendocytosis underlies retrograde signaling by neurotrophin receptors. J Neurosci (2005) 1.50
Plasma membrane expansion: a neuron's Herculean task. Nat Rev Neurosci (2009) 1.41
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins. J Cell Sci (2007) 1.39
Deletion of the SNARE vti1b in mice results in the loss of a single SNARE partner, syntaxin 8. Mol Cell Biol (2003) 1.38
A role for synaptotagmin VII-regulated exocytosis of lysosomes in neurite outgrowth from primary sympathetic neurons. J Neurosci (2006) 1.36
Neither type of mannose 6-phosphate receptor is sufficient for targeting of lysosomal enzymes along intracellular routes. J Cell Biol (1996) 1.36
Integrin signaling switches the cytoskeletal and exocytic machinery that drives neuritogenesis. Dev Cell (2010) 1.35
Roles of endosomal trafficking in neurite outgrowth and guidance. Trends Cell Biol (2009) 1.35
Commissure formation in the mammalian forebrain. Curr Opin Neurobiol (2007) 1.29
New insights into the mechanisms of macroautophagy in mammalian cells. Int Rev Cell Mol Biol (2008) 1.28
Amphiphysin I antisense oligonucleotides inhibit neurite outgrowth in cultured hippocampal neurons. J Neurosci (1998) 1.23
A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways. J Biol Chem (1998) 1.22
Identification of SNAP-47, a novel Qbc-SNARE with ubiquitous expression. J Biol Chem (2006) 1.19
Syntaxin 13 is a developmentally regulated SNARE involved in neurite outgrowth and endosomal trafficking. Eur J Neurosci (2000) 1.15
Timing of neuronal death in trkA, trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling. Development (1996) 1.13
The SNARE Vti1a-beta is localized to small synaptic vesicles and participates in a novel SNARE complex. J Neurosci (2000) 1.09
Identification of a developmentally regulated pathway of membrane retrieval in neuronal growth cones. J Cell Sci (2008) 1.06
Cross talk between tetanus neurotoxin-insensitive vesicle-associated membrane protein-mediated transport and L1-mediated adhesion. Mol Biol Cell (2003) 1.03
SNAREing the basis of multicellularity: consequences of protein family expansion during evolution. Mol Biol Evol (2008) 0.97
Characterization of the in vitro retrograde transport of MPR46. Traffic (2003) 0.95
Retinal axon guidance: novel mechanisms for steering. Curr Opin Neurobiol (2004) 0.95
Loss of SNAP29 impairs endocytic recycling and cell motility. PLoS One (2010) 0.93
Severe peripheral sensory neuron loss and modest motor neuron reduction in mice with combined deficiency of brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5. Dev Dyn (2000) 0.91
Syntaxin 6 regulates nerve growth factor-dependent neurite outgrowth. Neurosci Lett (2008) 0.87
Syntaxin 16 is enriched in neuronal dendrites and may have a role in neurite outgrowth. Mol Membr Biol (2008) 0.85
Mechanisms of TGF-beta-mediated apoptosis. Cell Tissue Res (2001) 1.72
Fibrosis and evidence for epithelial-mesenchymal transition in the kidneys of patients with staghorn calculi. BJU Int (2011) 1.55
The multiple facets of the TGF-β family cytokine growth/differentiation factor-15/macrophage inhibitory cytokine-1. Cytokine Growth Factor Rev (2013) 1.49
Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo. J Neurosci (2003) 1.40
Use1p is a yeast SNARE protein required for retrograde traffic to the ER. EMBO J (2003) 1.40
Deletion of the SNARE vti1b in mice results in the loss of a single SNARE partner, syntaxin 8. Mol Cell Biol (2003) 1.38
Tgfbeta2 -/- Tgfbeta3 -/- double knockout mice display severe midline fusion defects and early embryonic lethality. Anat Embryol (Berl) (2002) 1.12
Transient protonation changes in channelrhodopsin-2 and their relevance to channel gating. Proc Natl Acad Sci U S A (2013) 1.12
GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action. Neurobiol Dis (2006) 1.06
TGFβ signalling plays an important role in IL4-induced alternative activation of microglia. J Neuroinflammation (2012) 1.04
TGF-betas and their roles in the regulation of neuron survival. Adv Exp Med Biol (2002) 1.03
Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component. Cereb Cortex (2009) 1.01
Loss of transforming growth factor-beta 2 leads to impairment of central synapse function. Neural Dev (2008) 1.00
Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon. Stem Cells (2006) 1.00
Purification and characterization of two enantioselective alpha-ketoglutarate-dependent dioxygenases, RdpA and SdpA, from Sphingomonas herbicidovorans MH. Appl Environ Microbiol (2006) 0.97
Klf10 and Klf11 as mediators of TGF-beta superfamily signaling. Cell Tissue Res (2011) 0.94
The exocytosis of lytic granules is impaired in Vti1b- or Vamp8-deficient CTL leading to a reduced cytotoxic activity following antigen-specific activation. J Immunol (2010) 0.94
Mutation in the gene encoding lysosomal acid phosphatase (Acp2) causes cerebellum and skin malformation in mouse. Neurogenetics (2004) 0.94
Endogenous transforming growth factor-beta promotes quiescence of primary microglia in vitro. Glia (2012) 0.93
Nerve growth factor mediates activation of the Smad pathway in PC12 cells. Eur J Biochem (2004) 0.93
TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP. Neurobiol Dis (2010) 0.92
TGF-beta in dopamine neuron development, maintenance and neuroprotection. Adv Exp Med Biol (2009) 0.92
Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction. Stem Cells (2008) 0.91
Metabolomics of hexachlorocyclohexane (HCH) transformation: ratio of LinA to LinB determines metabolic fate of HCH isomers. Environ Microbiol (2012) 0.90
Neuregulin 1 type III/ErbB signaling is crucial for Schwann cell colonization of sympathetic axons. PLoS One (2011) 0.90
GDNF promotes neuronal differentiation and dopaminergic development of mouse mesencephalic neurospheres. Neurosci Lett (2004) 0.90
Reduced programmed cell death in the retina and defects in lens and cornea of Tgfbeta2(-/-) Tgfbeta3(-/-) double-deficient mice. Cell Tissue Res (2003) 0.90
TGF-beta is required for programmed cell death in interdigital webs of the developing mouse limb. Mech Dev (2002) 0.89
Induction and specification of midbrain dopaminergic cells: focus on SHH, FGF8, and TGF-beta. Cell Tissue Res (2004) 0.88
On the biodegradation of beta-peptides. Chembiochem (2002) 0.87
The role of transforming growth factor beta-2, beta-3 in mediating apoptosis in the murine intestinal mucosa. Gastroenterology (2002) 0.87
Transforming growth factor beta2 is released from PC12 cells via the regulated pathway of secretion. Mol Cell Neurosci (2003) 0.87
TGF-beta promotes survival on mesencephalic dopaminergic neurons in cooperation with Shh and FGF-8. Neurobiol Dis (2004) 0.86
IL6 protects MN9D cells and midbrain dopaminergic neurons from MPP+-induced neurodegeneration. Neuromolecular Med (2012) 0.86
Involvement of Fractin in TGF-beta-induced apoptosis in oligodendroglial progenitor cells. Glia (2009) 0.86
Tieg3/Klf11 induces apoptosis in OLI-neu cells and enhances the TGF-beta signaling pathway by transcriptional repression of Smad7. J Cell Biochem (2008) 0.86
Gene structure and evolution of Tieg3, a new member of the Tieg family of proteins. Gene (2004) 0.85
Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification. Eur J Neurosci (2006) 0.84
Functional domains of the TGF-beta-inducible transcription factor Tieg3 and detection of two putative nuclear localization signals within the zinc finger DNA-binding domain. J Cell Biochem (2007) 0.84
TGF-beta superfamily members, ActivinA and TGF-beta1, induce apoptosis in oligodendrocytes by different pathways. Cell Tissue Res (2008) 0.84
Description of Sphingosinicella xenopeptidilytica sp. nov., a beta-peptide-degrading species, and emended descriptions of the genus Sphingosinicella and the species Sphingosinicella microcystinivorans. Int J Syst Evol Microbiol (2007) 0.83
ApoER2 and VLDLr are required for mediating reelin signalling pathway for normal migration and positioning of mesencephalic dopaminergic neurons. PLoS One (2013) 0.82
TVP23 interacts genetically with the yeast SNARE VTI1 and functions in retrograde transport from the early endosome to the late Golgi. Biochem J (2009) 0.82
TGF-beta induces cell death in the oligodendroglial cell line OLI-neu. Glia (2002) 0.82
Dissecting Ent3p: the ENTH domain binds different SNAREs via distinct amino acid residues while the C-terminus is sufficient for retrograde transport from endosomes. Biochem J (2010) 0.82
PI3K-p110-alpha-subtype signalling mediates survival, proliferation and neurogenesis of cortical progenitor cells via activation of mTORC2. J Neurochem (2014) 0.82
Disruption of PLC-beta 1-mediated signal transduction in mutant mice causes age-dependent hippocampal mossy fiber sprouting and neurodegeneration. Mol Cell Neurosci (2002) 0.82
In vivo requirement of TGF-beta/GDNF cooperativity in mouse development: focus on the neurotrophic hypothesis. Int J Dev Neurosci (2008) 0.81
Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin. Cell Tissue Res (2008) 0.81
TIEG1 facilitates transforming growth factor-beta-mediated apoptosis in the oligodendroglial cell line OLI-neu. J Neurosci Res (2004) 0.80
Specificity in the crosstalk of TGFbeta/GDNF family members is determined by distinct GFR alpha receptors. J Neurochem (2007) 0.80
TGFβ1 increases microglia-mediated engulfment of apoptotic cells via upregulation of the milk fat globule-EGF factor 8. Glia (2014) 0.80
Distribution of microglia in the postnatal murine nigrostriatal system. Cell Tissue Res (2012) 0.79
Tieg1/Klf10 is upregulated by NGF and attenuates cell cycle progression in the pheochromocytoma cell line PC12. J Neurosci Res (2010) 0.79
The missing link in linear alkylbenzenesulfonate surfactant degradation: 4-sulfoacetophenone as a transient intermediate in the degradation of 3-(4-sulfophenyl)butyrate by Comamonas testosteroni KF-1. Appl Environ Microbiol (2009) 0.79
Rational design of a cytotoxic dinuclear Cu2 complex that binds by molecular recognition at two neighboring phosphates of the DNA backbone. Inorg Chem (2015) 0.79
Thapsigargin-induced Ca2+ increase inhibits TGFβ1-mediated Smad2 transcriptional responses via Ca2+/calmodulin-dependent protein kinase II. J Cell Biochem (2010) 0.78
Schwann cells migrate along axons in the absence of GDNF signaling. BMC Neurosci (2012) 0.78
Sim1 is a novel regulator in the differentiation of mouse dorsal raphe serotonergic neurons. PLoS One (2011) 0.78
Differentiation of embryonic stem cells. Curr Protoc Neurosci (2009) 0.77
Transforming growth factor-beta induced cell death in the developing chick retina is mediated via activation of c-jun N-terminal kinase and downregulation of the anti-apoptotic protein Bcl-X(L). Neurosci Lett (2002) 0.76
Development of methods for the bioanalysis of RRx-001 and metabolites. Bioanalysis (2014) 0.76
Establishment of a survival and toxic cellular model for Parkinson's disease from chicken mesencephalon. Neurotox Res (2012) 0.75
The dopaminergic nigrostriatal system: development, physiology, disease. Cell Tissue Res (2004) 0.75
Glia cell line-derived neurotrophic factor mediates survival of murine sympathetic precursors. J Neurosci Res (2013) 0.75
Aged Tgfbeta2/Gdnf double-heterozygous mice show no morphological and functional alterations in the nigrostriatal system. J Neural Transm (Vienna) (2010) 0.75
Analyzing murine Schwann cell development along growing axons. J Vis Exp (2012) 0.75
Importance of the N-terminal domain of the Qb-SNARE Vti1p for different membrane transport steps in the yeast endosomal system. PLoS One (2013) 0.75
Transforming growth factor-beta and tumor necrosis factor-alpha cooperate to induce apoptosis in the oligodendroglial cell line OLI-neu. J Neurosci Res (2003) 0.75
Isoform-specific role of transforming growth factor-beta2 in the regulation of proliferation and differentiation of murine adrenal chromaffin cells in vivo. J Neurosci Res (2004) 0.75
Investigating RET RTK signaling pathways using an IAP-based activity-profiling approach. J Proteome Res (2014) 0.75
[Emergency Department Interfaces]. Dtsch Med Wochenschr (2015) 0.75
Critical incidents during prehospital cardiopulmonary resuscitation: what are the problems nobody wants to talk about? Eur J Emerg Med (2011) 0.75
Na(+)/H(+) exchanger isoforms are differentially regulated in rat submandibular gland during acid/base disturbances in vivo. Cell Tissue Res (2005) 0.75
[One quarter of all readmissions are avoidable]. Dtsch Med Wochenschr (2016) 0.75