Published in EMBO J on July 15, 2003
A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1. Cell (2009) 2.24
An elaborate classification of SNARE proteins sheds light on the conservation of the eukaryotic endomembrane system. Mol Biol Cell (2007) 1.89
Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi. EMBO J (2004) 1.82
COPI-mediated transport. J Membr Biol (2006) 1.66
Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Nat Struct Mol Biol (2009) 1.36
Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS). PLoS One (2010) 1.28
Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion. EMBO J (2004) 1.28
Coat-tether interaction in Golgi organization. Mol Biol Cell (2008) 1.24
Dsl1p, Tip20p, and the novel Dsl3(Sec39) protein are required for the stability of the Q/t-SNARE complex at the endoplasmic reticulum in yeast. Mol Biol Cell (2005) 1.23
Membrane fusion by the GTPase atlastin requires a conserved C-terminal cytoplasmic tail and dimerization through the middle domain. Proc Natl Acad Sci U S A (2011) 1.18
The secretory system of Arabidopsis. Arabidopsis Book (2008) 1.16
RINT-1 regulates the localization and entry of ZW10 to the syntaxin 18 complex. Mol Biol Cell (2006) 1.15
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Localization of mRNAs coding for mitochondrial proteins in the yeast Saccharomyces cerevisiae. RNA (2011) 1.10
TANGO1 recruits ERGIC membranes to the endoplasmic reticulum for procollagen export. Elife (2015) 1.08
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Involvement of syntaxin 18, an endoplasmic reticulum (ER)-localized SNARE protein, in ER-mediated phagocytosis. Mol Biol Cell (2006) 1.04
Identification of the neuroblastoma-amplified gene product as a component of the syntaxin 18 complex implicated in Golgi-to-endoplasmic reticulum retrograde transport. Mol Biol Cell (2009) 1.03
High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic. Genome Res (2004) 1.02
Translation- and SRP-independent mRNA targeting to the endoplasmic reticulum in the yeast Saccharomyces cerevisiae. Mol Biol Cell (2013) 1.01
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ZW10 function in mitotic checkpoint control, dynein targeting and membrane trafficking: is dynein the unifying theme? Cell Cycle (2006) 0.94
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Organization of SNAREs within the Golgi stack. Cold Spring Harb Perspect Biol (2011) 0.88
Structure-based functional analysis reveals a role for the SM protein Sly1p in retrograde transport to the endoplasmic reticulum. Mol Biol Cell (2005) 0.87
The Dsl1 tethering complex actively participates in soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor (SNARE) complex assembly at the endoplasmic reticulum in Saccharomyces cerevisiae. J Biol Chem (2011) 0.85
Identification of functionally interacting SNAREs by using complementary substitutions in the conserved '0' layer. Mol Biol Cell (2005) 0.83
Live-cell assays to identify regulators of ER-to-Golgi trafficking. Traffic (2012) 0.82
ER Import Sites and Their Relationship to ER Exit Sites: A New Model for Bidirectional ER-Golgi Transport in Higher Plants. Front Plant Sci (2012) 0.82
ER-associated SNAREs and Sey1p mediate nuclear fusion at two distinct steps during yeast mating. Mol Biol Cell (2013) 0.81
The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Mol Biol Cell (2011) 0.80
SNAREs support atlastin-mediated homotypic ER fusion in Saccharomyces cerevisiae. J Cell Biol (2015) 0.79
The role of translation initiation regulation in haematopoiesis. Comp Funct Genomics (2012) 0.79
Grsf1-induced translation of the SNARE protein Use1 is required for expansion of the erythroid compartment. PLoS One (2014) 0.78
Evolution of the endomembrane systems of trypanosomatids - conservation and specialisation. J Cell Sci (2017) 0.76
Importance of the N-terminal domain of the Qb-SNARE Vti1p for different membrane transport steps in the yeast endosomal system. PLoS One (2013) 0.75
Development of a prediction system for tail-anchored proteins. BMC Bioinformatics (2016) 0.75
Functional profiling of the Saccharomyces cerevisiae genome. Nature (2002) 36.10
Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell (1980) 23.17
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature (1998) 15.80
A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast. J Cell Biol (1995) 12.18
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A rapid method for localized mutagenesis of yeast genes. Yeast (1992) 7.79
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Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs. Proc Natl Acad Sci U S A (1998) 4.99
A genomic perspective on membrane compartment organization. Nature (2001) 4.80
Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast. Mol Biol Cell (1996) 4.58
ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway. Cell (1990) 4.54
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell (1994) 4.47
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. J Cell Biol (1997) 4.16
Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum. Mol Biol Cell (1992) 3.81
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Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p. Cell (1995) 3.46
BET1, BOS1, and SEC22 are members of a group of interacting yeast genes required for transport from the endoplasmic reticulum to the Golgi complex. Mol Cell Biol (1990) 3.05
The VPS1 protein, a homolog of dynamin required for vacuolar protein sorting in Saccharomyces cerevisiae, is a GTPase with two functionally separable domains. J Cell Biol (1992) 2.69
The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p. J Cell Biol (1997) 2.50
SNARE-mediated retrograde traffic from the Golgi complex to the endoplasmic reticulum. Cell (1996) 2.44
Alternative pathways for the sorting of soluble vacuolar proteins in yeast: a vps35 null mutant missorts and secretes only a subset of vacuolar hydrolases. Mol Biol Cell (1992) 2.32
The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP. J Cell Biol (1995) 2.26
Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. Nat Struct Biol (2002) 2.21
COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants. J Cell Biol (1997) 2.16
A SNARE-like protein required for traffic through the Golgi complex. Nature (1995) 2.15
Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity. Proc Natl Acad Sci U S A (2002) 2.07
Asymmetric requirements for a Rab GTPase and SNARE proteins in fusion of COPII vesicles with acceptor membranes. J Cell Biol (2000) 1.97
New mutants of Saccharomyces cerevisiae affected in the transport of proteins from the endoplasmic reticulum to the Golgi complex. Genetics (1996) 1.89
A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum. EMBO J (1997) 1.88
Reconstitution of retrograde transport from the Golgi to the ER in vitro. J Cell Biol (1998) 1.87
Analysis of Sec22p in endoplasmic reticulum/Golgi transport reveals cellular redundancy in SNARE protein function. Mol Biol Cell (2002) 1.69
Geranylgeranylated SNAREs are dominant inhibitors of membrane fusion. J Cell Biol (2000) 1.66
SNAREs and the specificity of membrane fusion. Trends Cell Biol (2001) 1.60
Bet1p activates the v-SNARE Bos1p. Mol Biol Cell (1997) 1.39
The synaptobrevin-related domains of Bos1p and Sec22p bind to the syntaxin-like region of Sed5p. J Biol Chem (1997) 1.34
Kex2-dependent invertase secretion as a tool to study the targeting of transmembrane proteins which are involved in ER-->Golgi transport in yeast. EMBO J (1994) 1.32
The coatomer-interacting protein Dsl1p is required for Golgi-to-endoplasmic reticulum retrieval in yeast. J Biol Chem (2001) 1.24
High expression of the yeast syntaxin-related Vam3 protein suppresses the protein transport defects of a pep12 null mutant. FEBS Lett (1997) 1.18
Recycling of the yeast v-SNARE Sec22p involves COPI-proteins and the ER transmembrane proteins Ufe1p and Sec20p. J Cell Sci (1998) 1.08
Sec12p requires Rer1p for sorting to coatomer (COPI)-coated vesicles and retrieval to the ER. J Cell Sci (1997) 1.01
Predicting the distribution, conservation, and functions of SNAREs and related proteins in fungi. Fungal Genet Biol (2002) 0.91
The Saccharomyces cerevisiae early secretion mutant tip20 is synthetic lethal with mutants in yeast coatomer and the SNARE proteins Sec22p and Ufe1p. Yeast (1998) 0.90
X-ray structure of a protein-conducting channel. Nature (2003) 9.20
The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell (2008) 3.51
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. EMBO J (2002) 3.03
Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. EMBO J (2002) 2.17
Prokaryotic utilization of the twin-arginine translocation pathway: a genomic survey. J Bacteriol (2003) 2.07
Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes. EMBO J (2003) 1.89
NDC1: a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes. J Cell Biol (2006) 1.67
Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus. Nat Commun (2011) 1.65
Deletion of the SNARE vti1b in mice results in the loss of a single SNARE partner, syntaxin 8. Mol Cell Biol (2003) 1.38
ARF-GAP-mediated interaction between the ER-Golgi v-SNAREs and the COPI coat. J Cell Biol (2002) 1.30
In vivo analysis of importin alpha proteins reveals cellular proliferation inhibition and substrate specificity. Mol Cell Biol (2004) 1.29
Nuclear localization signal and protein context both mediate importin alpha specificity of nuclear import substrates. Mol Cell Biol (2006) 1.29
A role for mammalian Ubc6 homologues in ER-associated protein degradation. J Cell Sci (2002) 1.26
Dsl1p, an essential component of the Golgi-endoplasmic reticulum retrieval system in yeast, uses the same sequence motif to interact with different subunits of the COPI vesicle coat. J Biol Chem (2003) 1.25
Dsl1p, Tip20p, and the novel Dsl3(Sec39) protein are required for the stability of the Q/t-SNARE complex at the endoplasmic reticulum in yeast. Mol Biol Cell (2005) 1.23
Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi. EMBO J (2006) 1.22
Diversity and evolution of protein translocation. Annu Rev Microbiol (2005) 1.21
Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP. Hum Mol Genet (2008) 1.20
Differential expression of classical nuclear transport factors during cellular proliferation and differentiation. Cell Physiol Biochem (2002) 1.19
A link between ER tethering and COP-I vesicle uncoating. Dev Cell (2009) 1.14
Transient protonation changes in channelrhodopsin-2 and their relevance to channel gating. Proc Natl Acad Sci U S A (2013) 1.12
EcmPred: prediction of extracellular matrix proteins based on random forest with maximum relevance minimum redundancy feature selection. J Theor Biol (2012) 1.08
Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway. Biochim Biophys Acta (2008) 1.05
Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress. Mol Cell Biol (2006) 1.01
Normal brain development in importin-alpha5 deficient-mice. Nat Cell Biol (2007) 1.01
Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. Proc Natl Acad Sci U S A (2011) 0.95
Prediction of apoptosis protein locations with genetic algorithms and support vector machines through a new mode of pseudo amino acid composition. Protein Pept Lett (2010) 0.95
The exocytosis of lytic granules is impaired in Vti1b- or Vamp8-deficient CTL leading to a reduced cytotoxic activity following antigen-specific activation. J Immunol (2010) 0.94
A single Sec61-complex functions as a protein-conducting channel. Biochim Biophys Acta (2008) 0.90
Importin α7 is essential for zygotic genome activation and early mouse development. PLoS One (2011) 0.90
Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2. Biochem Biophys Res Commun (2009) 0.86
Mutations of the SM protein Sly1 resulting in bypass of GTPase requirement in vesicular transport are confined to a short helical region. FEBS Lett (2007) 0.85
TRAP assists membrane protein topogenesis at the mammalian ER membrane. Biochim Biophys Acta (2013) 0.85
Identification of functionally interacting SNAREs by using complementary substitutions in the conserved '0' layer. Mol Biol Cell (2005) 0.83
TVP23 interacts genetically with the yeast SNARE VTI1 and functions in retrograde transport from the early endosome to the late Golgi. Biochem J (2009) 0.82
SPRED: A machine learning approach for the identification of classical and non-classical secretory proteins in mammalian genomes. Biochem Biophys Res Commun (2009) 0.82
Dissecting Ent3p: the ENTH domain binds different SNAREs via distinct amino acid residues while the C-terminus is sufficient for retrograde transport from endosomes. Biochem J (2010) 0.82
RalA GTPase tethers insulin granules to L- and R-type calcium channels through binding α2 δ-1 subunit. Traffic (2013) 0.80
Rational design of a cytotoxic dinuclear Cu2 complex that binds by molecular recognition at two neighboring phosphates of the DNA backbone. Inorg Chem (2015) 0.79
Identification of importin α 7 specific transport cargoes using a proteomic screening approach. Mol Cell Proteomics (2014) 0.78
High-throughput sequencing of a single chromosome: a moth W chromosome. Chromosome Res (2013) 0.76
Peptides derived from the copper-binding region of lysyl oxidase exhibit antiangiogeneic properties by inhibiting enzyme activity: an in vitro study. J Pept Sci (2014) 0.76
Importance of the N-terminal domain of the Qb-SNARE Vti1p for different membrane transport steps in the yeast endosomal system. PLoS One (2013) 0.75
Single rRNA helices bind independently to the protein-conducting channel SecYEG. Traffic (2013) 0.75
Investigating RET RTK signaling pathways using an IAP-based activity-profiling approach. J Proteome Res (2014) 0.75