Published in Dev Biol on January 27, 2011
Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling. J Biol Chem (2013) 0.83
A novel role for FOXA2 and SHH in organizing midbrain signaling centers. Dev Biol (2012) 0.82
Hedgehog activity controls opening of the primary mouth. Dev Biol (2014) 0.82
The zebrafish tailbud contains two independent populations of midline progenitor cells that maintain long-term germ layer plasticity and differentiate in response to local signaling cues. Development (2015) 0.81
Cell segregation, mixing, and tissue pattern in the spinal cord of the Xenopus laevis neurula. Dev Dyn (2013) 0.76
Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis. Commun Integr Biol (2017) 0.75
Notch signaling: cell fate control and signal integration in development. Science (1999) 28.83
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature (1996) 11.46
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev (2002) 8.56
Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature (1998) 8.02
Notch signaling: from the outside in. Dev Biol (2000) 6.06
A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell (2000) 5.49
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell (1996) 5.45
Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell (1994) 4.53
The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell (2003) 3.66
Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development (1997) 3.48
Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell (1991) 3.40
The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. Cell (1999) 3.15
nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development (1997) 3.15
A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development (1994) 3.12
Specification of neuronal fates in the ventral neural tube. Curr Opin Neurobiol (2001) 3.11
Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development (1998) 2.94
Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes Dev (1999) 2.90
Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. Cell (1995) 2.85
Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development (1998) 2.67
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell (1994) 2.58
fork head domain genes in zebrafish. Dev Genes Evol (1998) 2.58
Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants. Nature (1995) 2.46
Control of cell pattern in the developing nervous system: polarizing activity of the floor plate and notochord. Cell (1991) 2.31
The Xenopus homolog of Drosophila Suppressor of Hairless mediates Notch signaling during primary neurogenesis. Development (1997) 2.30
Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate. Cell (1993) 2.12
Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature (1998) 2.10
A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord. Genes Dev (2002) 2.09
Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish. Development (1998) 2.08
beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation. Dev Biol (2005) 2.06
F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension. Cell (1992) 2.05
Chemotropic guidance of developing axons in the mammalian central nervous system. Nature (1989) 2.01
Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC. Neuron (1997) 2.00
A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain. Genes Dev (1992) 1.96
The role of paraxial protocadherin in selective adhesion and cell movements of the mesoderm during Xenopus gastrulation. Development (1998) 1.84
cyclops encodes a nodal-related factor involved in midline signaling. Proc Natl Acad Sci U S A (1998) 1.75
Discussion point. Origin and specification of the neural tube floor plate: insights from the chick and zebrafish. Curr Opin Neurobiol (2000) 1.67
Fate map for the 32-cell stage of Xenopus laevis. Development (1987) 1.67
Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development (1996) 1.65
Induction of embryonic primordia by implantation of organizers from a different species. 1923. Int J Dev Biol (2001) 1.62
Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog. PLoS Biol (2010) 1.58
Induction of the Xenopus organizer: expression and regulation of Xnot, a novel FGF and activin-regulated homeo box gene. Genes Dev (1993) 1.56
Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis. Development (1992) 1.55
Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. Genes Dev (2010) 1.51
Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis. Proc Natl Acad Sci U S A (1999) 1.41
Induction of floor plate differentiation by contact-dependent, homeogenetic signals. Development (1993) 1.40
The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system. Nature (1991) 1.39
Vital dye mapping of the gastrula and neurula of Xenopus laevis. I. Prospective areas and morphogenetic movements of the superficial layer. Dev Biol (1975) 1.35
Sequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plate. Mech Dev (1993) 1.34
Brachyury--a gene affecting mouse gastrulation and early organogenesis. Dev Suppl (1992) 1.31
Vital dye mapping of the gastrula and neurula of Xenopus laevis. II. Prospective areas and morphogenetic movements of the deep layer. Dev Biol (1976) 1.29
Mesodermal control of neural cell identity: floor plate induction by the notochord. Science (1990) 1.29
Neovascularization of the Xenopus embryo. Dev Dyn (1997) 1.24
Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis. Development (1995) 1.22
Node and midline defects are associated with left-right development in Delta1 mutant embryos. Development (2003) 1.21
The cleavage stage origin of Spemann's Organizer: analysis of the movements of blastomere clones before and during gastrulation in Xenopus. Development (1994) 1.20
Delta-mediated specification of midline cell fates in zebrafish embryos. Curr Biol (1999) 1.12
Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. Dev Biol (2000) 1.12
Direct action of the nodal-related signal cyclops in induction of sonic hedgehog in the ventral midline of the CNS. Development (2000) 1.10
The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning. EMBO J (2007) 1.09
Delta-Notch signaling and lateral inhibition in zebrafish spinal cord development. BMC Dev Biol (2001) 1.08
Hedgehog and retinoid signalling confines nkx2.2b expression to the lateral floor plate of the zebrafish trunk. Mech Dev (2005) 1.07
A spinal cord fate map in the avian embryo: while regressing, Hensen's node lays down the notochord and floor plate thus joining the spinal cord lateral walls. Development (1996) 1.06
Axial protocadherin is a mediator of prenotochord cell sorting in Xenopus. Dev Biol (2002) 1.04
Distinct modes of floor plate induction in the chick embryo. Development (2003) 1.02
Vertebrate floor-plate specification: variations on common themes. Trends Genet (2004) 1.01
Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant. Development (1990) 1.01
Organization and development of the tail bud analyzed with the quail-chick chimaera system. Mech Dev (1995) 0.97
Notch activates sonic hedgehog and both are involved in the specification of dorsal midline cell-fates in Xenopus. Development (2003) 0.96
one-eyed pinhead is required for development of the ventral midline of the zebrafish (Danio rerio) neural tube. Genes Funct (1997) 0.95
Dual origin of the floor plate in the avian embryo. Development (2002) 0.95
The relationships between notochord and floor plate in vertebrate development revisited. Proc Natl Acad Sci U S A (1998) 0.95
Notch signaling regulates midline cell specification and proliferation in zebrafish. Dev Biol (2006) 0.95
Restrictions to floor plate induction by hedgehog and winged-helix genes in the neural tube of frog embryos. Mol Cell Neurosci (1995) 0.93
A temperature-sensitive mutation in the nodal-related gene cyclops reveals that the floor plate is induced during gastrulation in zebrafish. Development (2003) 0.90
Floor plate develops upon depletion of tiggy-winkle and sonic hedgehog. Genesis (2001) 0.89
Delta-Notch signaling induces hypochord development in zebrafish. Development (2002) 0.89
Discontinuous organization and specification of the lateral floor plate in zebrafish. Dev Biol (2006) 0.87
BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus. Dev Biol (2009) 0.87
Discussion point. The case for floor plate induction by the notochord. Curr Opin Neurobiol (2000) 0.86
Hedgehog signaling regulates the amount of hypaxial muscle development during Xenopus myogenesis. Dev Biol (2007) 0.86
A Xenopus homebox gene defines dorsal-ventral domains in the developing brain. Development (1993) 0.85
Notch activity is required to maintain floorplate identity and to control neurogenesis in the chick hindbrain and spinal cord. Int J Dev Biol (2003) 0.84
Medial floor plate formation in zebrafish consists of two phases and requires trunk-derived Midkine-a. Genes Dev (2005) 0.83
Characterization of a subfamily of related winged helix genes, XFD-12/12'/12" (XFLIP), during Xenopus embryogenesis. Mech Dev (1999) 0.82
Delayed formation of the floor plate after ablation of the avian notochord. Neuron (1993) 0.82
The Notch-target gene hairy2a impedes the involution of notochordal cells by promoting floor plate fates in Xenopus embryos. Development (2005) 0.81
Lymph heart musculature is under distinct developmental control from lymphatic endothelium. Dev Biol (2010) 0.81
lunatic fringe regulates Delta-Notch induction of hypochord in zebrafish. Dev Dyn (2003) 0.80
A restrictive role for Hedgehog signalling during otic specification in Xenopus. Dev Biol (2003) 0.80
Notch signalling regulates the contribution of progenitor cells from the chick Hensen's node to the floor plate and notochord. Development (2010) 0.80
A family of Xenopus BTB-Kelch repeat proteins related to ENC-1: new markers for early events in floorplate and placode development. Gene Expr Patterns (2003) 0.79
XFKH2, a Xenopus HNF-3 alpha homologue, exhibits both activin-inducible and autonomous phases of expression in early embryos. Dev Biol (1993) 0.79
Distinct expression of two types of Xenopus Patched genes during early embryogenesis and hindlimb development. Mech Dev (2000) 0.78
XHRT-1, a hairy and Enhancer of split related gene with expression in floor plate and hypochord during early Xenopus embryogenesis. Dev Genes Evol (2002) 0.77
Primitive glial compartments in the floor plate of mammalian embryos: distinct progenitors of adult astrocytes and microglia support the notoplate hypothesis. Perspect Dev Neurobiol (1993) 0.76
The genome of the Western clawed frog Xenopus tropicalis. Science (2010) 4.70
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet (2006) 3.97
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat Genet (2008) 3.84
Convergent extension: the molecular control of polarized cell movement during embryonic development. Dev Cell (2002) 3.81
Mutations in VANGL1 associated with neural-tube defects. N Engl J Med (2007) 3.58
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development (2006) 2.96
Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. Science (2010) 2.89
Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis. Nat Genet (2009) 2.84
Systematic discovery of nonobvious human disease models through orthologous phenotypes. Proc Natl Acad Sci U S A (2010) 2.61
Neural tube closure requires Dishevelled-dependent convergent extension of the midline. Development (2002) 2.52
Shroom induces apical constriction and is required for hingepoint formation during neural tube closure. Curr Biol (2003) 2.49
Techniques and probes for the study of Xenopus tropicalis development. Dev Dyn (2002) 2.34
Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning. Nat Genet (2003) 2.31
The BMP antagonist noggin regulates cranial suture fusion. Nature (2003) 2.09
Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases. Proc Natl Acad Sci U S A (2011) 1.90
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol (2009) 1.90
Developmental anomalies of the cervical spine in patients with fibrodysplasia ossificans progressiva are distinctly different from those in patients with Klippel-Feil syndrome: clues from the BMP signaling pathway. Spine (Phila Pa 1976) (2005) 1.81
Targeted deletion of Sost distal enhancer increases bone formation and bone mass. Proc Natl Acad Sci U S A (2012) 1.78
Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures. Dev Cell (2005) 1.72
Shroom family proteins regulate gamma-tubulin distribution and microtubule architecture during epithelial cell shape change. Development (2007) 1.64
Xenopus tropicalis egg extracts provide insight into scaling of the mitotic spindle. J Cell Biol (2007) 1.63
Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension. Nat Genet (2012) 1.62
microRNA-24a is required to repress apoptosis in the developing neural retina. Genes Dev (2009) 1.61
Accelerated gene evolution and subfunctionalization in the pseudotetraploid frog Xenopus laevis. BMC Biol (2007) 1.59
Subcellular localization and signaling properties of dishevelled in developing vertebrate embryos. Curr Biol (2005) 1.58
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol (2012) 1.58
Characterization of a Mycobacterium ulcerans-like infection in a colony of African tropical clawed frogs (Xenopus tropicalis). Comp Med (2004) 1.52
Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals. Development (2003) 1.49
Identification of novel ciliogenesis factors using a new in vivo model for mucociliary epithelial development. Dev Biol (2007) 1.46
Actomyosin contractility and microtubules drive apical constriction in Xenopus bottle cells. Dev Biol (2007) 1.33
FGF8 spliceforms mediate early mesoderm and posterior neural tissue formation in Xenopus. Development (2006) 1.29
PCP and septins compartmentalize cortical actomyosin to direct collective cell movement. Science (2014) 1.24
Coordinated genomic control of ciliogenesis and cell movement by RFX2. Elife (2014) 1.20
Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium. Development (2006) 1.19
Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination. Development (2010) 1.15
In vivo imaging reveals a role for Cdc42 in spindle positioning and planar orientation of cell divisions during vertebrate neural tube closure. J Cell Sci (2009) 1.13
Identification of mutants in inbred Xenopus tropicalis. Mech Dev (2005) 1.13
Control of vertebrate intraflagellar transport by the planar cell polarity effector Fuz. J Cell Biol (2012) 1.11
High-magnification in vivo imaging of Xenopus embryos for cell and developmental biology. Cold Spring Harb Protoc (2010) 1.10
Regional requirements for Dishevelled signaling during Xenopus gastrulation: separable effects on blastopore closure, mesendoderm internalization and archenteron formation. Development (2004) 1.10
Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation. Development (2007) 1.08
Rapid gynogenetic mapping of Xenopus tropicalis mutations to chromosomes. Dev Dyn (2009) 1.08
RFX2 is broadly required for ciliogenesis during vertebrate development. Dev Biol (2011) 1.06
Endocytosis is required for efficient apical constriction during Xenopus gastrulation. Curr Biol (2010) 1.04
The shroom family proteins play broad roles in the morphogenesis of thickened epithelial sheets. Dev Dyn (2009) 1.03
Regulation of ciliary polarity by the APC/C. Proc Natl Acad Sci U S A (2009) 1.03
Cooperative activity of noggin and gremlin 1 in axial skeleton development. Development (2011) 1.03
Developmental regulation of central spindle assembly and cytokinesis during vertebrate embryogenesis. Curr Biol (2008) 1.01
The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus. Dev Dyn (2008) 0.99
Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Dev Cell (2013) 0.99
JAWS coordinates chondrogenesis and synovial joint positioning. Development (2008) 0.99
Effects of heterodimerization and proteolytic processing on Derrière and Nodal activity: implications for mesoderm induction in Xenopus. Development (2002) 0.98
Cloning and characterization of Xenopus Id4 reveals differing roles for Id genes. Dev Biol (2003) 0.98
Genetic evidence that SOST inhibits WNT signaling in the limb. Dev Biol (2010) 0.98
A novel role for lbx1 in Xenopus hypaxial myogenesis. Development (2005) 0.98
Direct activation of Shroom3 transcription by Pitx proteins drives epithelial morphogenesis in the developing gut. Development (2010) 0.98
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling. Science (2013) 0.95
fus/TLS orchestrates splicing of developmental regulators during gastrulation. Genes Dev (2012) 0.92
Diversification of the expression patterns and developmental functions of the dishevelled gene family during chordate evolution. Dev Dyn (2009) 0.92
Proteomic profiling of cardiac tissue by isolation of nuclei tagged in specific cell types (INTACT). Development (2014) 0.92
A role for central spindle proteins in cilia structure and function. Cytoskeleton (Hoboken) (2011) 0.90
Osteopotentia regulates osteoblast maturation, bone formation, and skeletal integrity in mice. J Cell Biol (2010) 0.90
Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner. Dev Biol (2013) 0.89
Microinjection of Xenopus embryos. Cold Spring Harb Protoc (2010) 0.89
Cloning and expression of Xenopus Prickle, an orthologue of a Drosophila planar cell polarity gene. Mech Dev (2002) 0.89
Expression of microRNAs during embryonic development of Xenopus tropicalis. Gene Expr Patterns (2008) 0.89
New tools for visualization and analysis of morphogenesis in spherical embryos. Dev Dyn (2005) 0.89
Tail morphogenesis in the ascidian, Ciona intestinalis, requires cooperation between notochord and muscle. Dev Biol (2002) 0.89
Embryogenesis and laboratory maintenance of the foam-nesting túngara frogs, genus Engystomops (= Physalaemus). Dev Dyn (2009) 0.88
Old can be new again: HAPPY whole genome sequencing, mapping and assembly. Int J Biol Sci (2009) 0.88
BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus. Dev Biol (2009) 0.87
A new standard nomenclature for proteins related to Apx and Shroom. BMC Cell Biol (2006) 0.87
Expression cloning in Xenopus identifies RNA-binding proteins as regulators of embryogenesis and Rbmx as necessary for neural and muscle development. Dev Dyn (2008) 0.87
Control of intercalation is cell-autonomous in the notochord of Ciona intestinalis. Dev Biol (2002) 0.86
Expression of Xenopus tropicalis noggin1 and noggin2 in early development: two noggin genes in a tetrapod. Gene Expr Patterns (2004) 0.86
Hedgehog signaling regulates the amount of hypaxial muscle development during Xenopus myogenesis. Dev Biol (2007) 0.86
Twisted gastrulation is required for forebrain specification and cooperates with Chordin to inhibit BMP signaling during X. tropicalis gastrulation. Dev Biol (2006) 0.85
Developmental expression of FoxJ1.2, FoxJ2, and FoxQ1 in Xenopus tropicalis. Gene Expr Patterns (2006) 0.85
Inhibition of neurogenesis by SRp38, a neuroD-regulated RNA-binding protein. Development (2005) 0.85
Xenopus laevis In Vitro Fertilization and Natural Mating Methods. CSH Protoc (2007) 0.84
The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development. Dev Biol (2002) 0.83
Function of the two Xenopus smad4s in early frog development. J Biol Chem (2006) 0.82
Sp8 regulates inner ear development. Proc Natl Acad Sci U S A (2014) 0.82
Animal Cap Isolation from Xenopus laevis. CSH Protoc (2007) 0.81
Lymph heart musculature is under distinct developmental control from lymphatic endothelium. Dev Biol (2010) 0.81
Dejellying Xenopus laevis Embryos. CSH Protoc (2007) 0.81
Closing in on vertebrate planar polarity. Nat Cell Biol (2004) 0.81
Nkx6 genes pattern the frog neural plate and Nkx6.1 is necessary for motoneuron axon projection. Dev Biol (2010) 0.80
Whole transcriptome analysis with sequencing: methods, challenges and potential solutions. Cell Mol Life Sci (2015) 0.80
Targeted gene disruption with engineered zinc-finger nucleases (ZFNs). Methods Mol Biol (2012) 0.80
Dazap2 is required for FGF-mediated posterior neural patterning, independent of Wnt and Cdx function. Dev Biol (2009) 0.80
Calibration of the injection volume for microinjection of Xenopus oocytes and embryos. Cold Spring Harb Protoc (2010) 0.79
Synthesis and purification of digoxigenin-labeled RNA probes for in situ hybridization. CSH Protoc (2007) 0.79
A family of Xenopus BTB-Kelch repeat proteins related to ENC-1: new markers for early events in floorplate and placode development. Gene Expr Patterns (2003) 0.79
Removing the Vitelline Membrane from Xenopus laevis Embryos. CSH Protoc (2007) 0.78
Xenopus laevis Animal Cap/Vegetal Endoderm Conjugates. CSH Protoc (2007) 0.78
Baskets for in situ hybridization and immunohistochemistry. CSH Protoc (2007) 0.78