Published in Proc Natl Acad Sci U S A on January 31, 2011
Walking to work: roles for class V myosins as cargo transporters. Nat Rev Mol Cell Biol (2011) 1.93
Organization and execution of the epithelial polarity programme. Nat Rev Mol Cell Biol (2014) 1.67
Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex. Dev Cell (2011) 1.50
GLUT4 exocytosis. J Cell Sci (2011) 1.50
Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nat Cell Biol (2012) 1.42
Role of membrane traffic in the generation of epithelial cell asymmetry. Nat Cell Biol (2012) 1.33
Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. J Biol Chem (2012) 1.32
Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice. J Clin Invest (2012) 1.31
A molecular switch for the orientation of epithelial cell polarization. Dev Cell (2014) 1.27
Identification of myosin XI receptors in Arabidopsis defines a distinct class of transport vesicles. Plant Cell (2013) 1.13
Polarized sorting and trafficking in epithelial cells. Cell Res (2012) 1.06
Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease. J Clin Invest (2014) 1.02
The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway. PLoS One (2012) 1.02
Myo5b knockout mice as a model of microvillus inclusion disease. Sci Rep (2015) 0.99
Arabidopsis Myosin XI-K Localizes to the Motile Endomembrane Vesicles Associated with F-actin. Front Plant Sci (2012) 0.98
Phosphorylation of Rab11-FIP2 regulates polarity in MDCK cells. Mol Biol Cell (2012) 0.98
Myosin motors at neuronal synapses: drivers of membrane transport and actin dynamics. Nat Rev Neurosci (2013) 0.97
An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking. Proc Natl Acad Sci U S A (2015) 0.93
Myosin-X functions in polarized epithelial cells. Mol Biol Cell (2012) 0.93
A Rab11a-Rab8a-Myo5B network promotes stretch-regulated exocytosis in bladder umbrella cells. Mol Biol Cell (2013) 0.93
Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22. PLoS One (2012) 0.93
Cargo sorting in the endocytic pathway: a key regulator of cell polarity and tissue dynamics. Cold Spring Harb Perspect Biol (2014) 0.93
Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis. J Biol Chem (2012) 0.92
Structural basis of myosin V Rab GTPase-dependent cargo recognition. Proc Natl Acad Sci U S A (2013) 0.91
Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3. J Cell Biol (2015) 0.90
Myosin Va mediates Rab8A-regulated GLUT4 vesicle exocytosis in insulin-stimulated muscle cells. Mol Biol Cell (2014) 0.90
Rab11-FIP2 interaction with MYO5B regulates movement of Rab11a-containing recycling vesicles. Traffic (2014) 0.88
Rab11a regulates syntaxin 3 localization and microvillus assembly in enterocytes. J Cell Sci (2015) 0.88
Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche. Development (2015) 0.88
Rab25 regulates integrin expression in polarized colonic epithelial cells. Mol Biol Cell (2013) 0.87
Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes. Circ Res (2014) 0.85
Myosin Vb mediated plasma membrane homeostasis regulates peridermal cell size and maintains tissue homeostasis in the zebrafish epidermis. PLoS Genet (2014) 0.82
Huntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKC. PLoS Biol (2015) 0.81
Recycling endosomes. Curr Opin Cell Biol (2015) 0.81
RAB and RHO GTPases regulate intestinal crypt cell homeostasis and enterocyte function. Small GTPases (2016) 0.81
Coupling of two non-processive myosin 5c dimers enables processive stepping along actin filaments. Sci Rep (2014) 0.81
MYO5B is epigenetically silenced and associated with MET signaling in human gastric cancer. Dig Dis Sci (2013) 0.81
Towards understanding microvillus inclusion disease. Mol Cell Pediatr (2016) 0.80
Vangl2 cooperates with Rab11 and Myosin V to regulate apical constriction during vertebrate gastrulation. Development (2014) 0.80
Plasticity of the brush border - the yin and yang of intestinal homeostasis. Nat Rev Gastroenterol Hepatol (2016) 0.79
Compartmentalizing intestinal epithelial cell toll-like receptors for immune surveillance. Cell Mol Life Sci (2015) 0.78
Inactivation of MYO5B promotes invasion and motility in gastric cancer cells. Dig Dis Sci (2011) 0.78
Recycling Endosomes and Viral Infection. Viruses (2016) 0.77
Transcriptional fingerprinting of "browning" white fat identifies NRG4 as a novel adipokine. Adipocyte (2014) 0.77
CLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer- and actin-mediated endocytic trafficking. Nat Commun (2016) 0.76
p114RhoGEF governs cell motility and lumen formation during tubulogenesis through a ROCK-myosin-II pathway. J Cell Sci (2015) 0.75
Rab11-FIP1A regulates early trafficking into the recycling endosomes. Exp Cell Res (2016) 0.75
Rab7b at the intersection of intracellular trafficking and cell migration. Commun Integr Biol (2015) 0.75
Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes. Elife (2016) 0.75
Rab14 specifies the apical membrane through Arf6-mediated regulation of lipid domains and Cdc42. Sci Rep (2016) 0.75
New Insights into How Trafficking Regulates T Cell Receptor Signaling. Front Cell Dev Biol (2016) 0.75
Vps33b is Crucial for Structural and Functional Hepatocyte Polarity. J Hepatol (2017) 0.75
Regulation of podocalyxin trafficking by Rab small GTPases in epithelial cells. Small GTPases (2016) 0.75
Acquisition of Rab11 and Rab11-Fip2-A novel strategy for Chlamydia pneumoniae early survival. PLoS Pathog (2017) 0.75
Disruption of Rab8a and Rab11a causes formation of basolateral microvilli in neonatal enteropathy. J Cell Sci (2017) 0.75
Rab11 regulates recycling through the pericentriolar recycling endosome. J Cell Biol (1996) 9.27
Rabs and their effectors: achieving specificity in membrane traffic. Proc Natl Acad Sci U S A (2006) 6.83
From cells to organs: building polarized tissue. Nat Rev Mol Cell Biol (2008) 5.06
Organization of vesicular trafficking in epithelia. Nat Rev Mol Cell Biol (2005) 4.79
Opinion: Building epithelial architecture: insights from three-dimensional culture models. Nat Rev Mol Cell Biol (2002) 4.76
Imaging protein-protein interactions using fluorescence resonance energy transfer microscopy. Methods (2001) 3.90
A molecular network for de novo generation of the apical surface and lumen. Nat Cell Biol (2010) 3.70
Myosin vb is associated with plasma membrane recycling systems. Mol Biol Cell (2001) 3.45
The Rab8 GTPase regulates apical protein localization in intestinal cells. Nature (2007) 3.01
Coordination of Rab8 and Rab11 in primary ciliogenesis. Proc Natl Acad Sci U S A (2010) 2.88
Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling. J Biol Chem (2002) 2.32
MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity. Nat Genet (2008) 2.24
Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells. J Cell Biol (2005) 2.06
Mature chief cells are cryptic progenitors for metaplasia in the stomach. Gastroenterology (2010) 2.02
Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3. Mol Biol Cell (2007) 1.96
Characterization of the Rab8-specific membrane traffic route linked to protrusion formation. J Cell Sci (2006) 1.93
Myosin V, Rab11, and dRip11 direct apical secretion and cellular morphogenesis in developing Drosophila photoreceptors. J Cell Biol (2007) 1.76
Human myosin-Vc is a novel class V myosin expressed in epithelial cells. J Cell Sci (2002) 1.72
The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity. J Cell Biol (2009) 1.68
Rab11a and myosin Vb are required for bile canalicular formation in WIF-B9 cells. Proc Natl Acad Sci U S A (2005) 1.53
Alternative splicing in class V myosins determines association with Rab10. J Biol Chem (2008) 1.45
Direct interaction between a myosin V motor and the Rab GTPases Ypt31/32 is required for polarized secretion. Mol Biol Cell (2008) 1.45
ROCK-mediated contractility, tight junctions and channels contribute to the conversion of a preapical patch into apical surface during isochoric lumen initiation. J Cell Sci (2008) 1.30
MARK2/EMK1/Par-1Balpha phosphorylation of Rab11-family interacting protein 2 is necessary for the timely establishment of polarity in Madin-Darby canine kidney cells. Mol Biol Cell (2006) 1.27
Apical secretion in epithelial tubes of the Drosophila embryo is directed by the Formin-family protein Diaphanous. Dev Cell (2009) 1.21
Loss-of-function of MYO5B is the main cause of microvillus inclusion disease: 15 novel mutations and a CaCo-2 RNAi cell model. Hum Mutat (2010) 1.20
Apical cargo traverses endosomal compartments on the passage to the cell surface. Traffic (2008) 1.05
A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell (2006) 6.15
Gastric cancer originating from bone marrow-derived cells. Science (2004) 6.04
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. Cell (2007) 5.84
From cells to organs: building polarized tissue. Nat Rev Mol Cell Biol (2008) 5.06
Opinion: Building epithelial architecture: insights from three-dimensional culture models. Nat Rev Mol Cell Biol (2002) 4.76
A molecular network for de novo generation of the apical surface and lumen. Nat Cell Biol (2010) 3.70
Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development (2007) 3.56
Genetic control of single lumen formation in the zebrafish gut. Nat Cell Biol (2007) 3.07
Beta1-integrin orients epithelial polarity via Rac1 and laminin. Mol Biol Cell (2004) 2.95
ERK and MMPs sequentially regulate distinct stages of epithelial tubule development. Dev Cell (2004) 2.73
The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b. Science (2010) 2.73
Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling. J Biol Chem (2002) 2.32
Epithelial polarity and tubulogenesis in vitro. Trends Cell Biol (2003) 2.31
Mature chief cells are cryptic progenitors for metaplasia in the stomach. Gastroenterology (2010) 2.02
The pericentriolar recycling endosome plays a key role in Vpu-mediated enhancement of HIV-1 particle release. Traffic (2006) 1.97
Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3. Mol Biol Cell (2007) 1.96
Molecular regulation of lumen morphogenesis. Curr Biol (2011) 1.96
Alterations in gastric mucosal lineages induced by acute oxyntic atrophy in wild-type and gastrin-deficient mice. Am J Physiol Gastrointest Liver Physiol (2005) 1.94
RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. Mol Cell (2009) 1.94
Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation. Nat Genet (2006) 1.92
A molecular signature of gastric metaplasia arising in response to acute parietal cell loss. Gastroenterology (2007) 1.88
Potentiation of oxyntic atrophy-induced gastric metaplasia in amphiregulin-deficient mice. Gastroenterology (2007) 1.87
Exocytosis: the many masters of the exocyst. Curr Biol (2002) 1.85
Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures. Mol Biol Cell (2003) 1.82
The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor. Nat Cell Biol (2004) 1.80
The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum. J Biol Chem (2003) 1.73
The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis. J Cell Biol (2010) 1.70
Rab11-family interacting protein 2 and myosin Vb are required for CXCR2 recycling and receptor-mediated chemotaxis. Mol Biol Cell (2004) 1.70
Exocyst requirement for endocytic traffic directed toward the apical and basolateral poles of polarized MDCK cells. Mol Biol Cell (2007) 1.69
The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity. J Cell Biol (2009) 1.68
Spasmolytic polypeptide-expressing metaplasia (SPEM) in the gastric oxyntic mucosa does not arise from Lgr5-expressing cells. Gut (2011) 1.67
EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin. J Cell Sci (2007) 1.64
Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer. Gastroenterology (2010) 1.64
The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling. J Cell Sci (2008) 1.64
A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle. Traffic (2006) 1.62
Slug is required for cell survival during partial epithelial-mesenchymal transition of HGF-induced tubulogenesis. Mol Biol Cell (2007) 1.61
Involvement of myosin Vb in glutamate receptor trafficking. J Biol Chem (2005) 1.61
Morphological and biochemical analysis of Rac1 in three-dimensional epithelial cell cultures. Methods Enzymol (2006) 1.59
Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2. Proc Natl Acad Sci U S A (2008) 1.55
Rab11a and myosin Vb regulate recycling of the M4 muscarinic acetylcholine receptor. J Neurosci (2002) 1.54
Spasmolytic polypeptide expressing metaplasia to preneoplasia in H. felis-infected mice. Gastroenterology (2004) 1.52
Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteins. EMBO J (2007) 1.51
Characterization of immunoisolated human gastric parietal cells tubulovesicles: identification of regulators of apical recycling. Am J Physiol Gastrointest Liver Physiol (2007) 1.49
TFF2 mRNA transcript expression marks a gland progenitor cell of the gastric oxyntic mucosa. Gastroenterology (2010) 1.45
Alternative splicing in class V myosins determines association with Rab10. J Biol Chem (2008) 1.45
Liver progenitor cells develop cholangiocyte-type epithelial polarity in three-dimensional culture. Mol Biol Cell (2007) 1.44
Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nat Cell Biol (2012) 1.42
Polarity proteins PAR6 and aPKC regulate cell death through GSK-3beta in 3D epithelial morphogenesis. J Cell Sci (2007) 1.42
Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity. EMBO Rep (2008) 1.40
Bone morphogenetic protein signaling regulates gastric epithelial cell development and proliferation in mice. Gastroenterology (2010) 1.38
Differential regulation of CXCR2 trafficking by Rab GTPases. Blood (2002) 1.38
The transcription factor MIST1 is a novel human gastric chief cell marker whose expression is lost in metaplasia, dysplasia, and carcinoma. Am J Pathol (2010) 1.37
Rab11b resides in a vesicular compartment distinct from Rab11a in parietal cells and other epithelial cells. Exp Cell Res (2003) 1.35
Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas. J Clin Invest (2010) 1.35
Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism. PLoS Pathog (2012) 1.34
Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells. Proc Natl Acad Sci U S A (2003) 1.33
Role of membrane traffic in the generation of epithelial cell asymmetry. Nat Cell Biol (2012) 1.33
Emergence of spasmolytic polypeptide-expressing metaplasia in Mongolian gerbils infected with Helicobacter pylori. Lab Invest (2007) 1.32
Spasmolytic polypeptide-expressing metaplasia and intestinal metaplasia: time for reevaluation of metaplasias and the origins of gastric cancer. Gastroenterology (2010) 1.28
MARK2/EMK1/Par-1Balpha phosphorylation of Rab11-family interacting protein 2 is necessary for the timely establishment of polarity in Madin-Darby canine kidney cells. Mol Biol Cell (2006) 1.27
RabGEFs are a major determinant for specific Rab membrane targeting. J Cell Biol (2013) 1.26
A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor. Nat Cell Biol (2010) 1.25
Expression and prognostic significance of prothymosin-alpha and ERp57 in human gastric cancer. Surgery (2006) 1.25
Simulating properties of in vitro epithelial cell morphogenesis. PLoS Comput Biol (2006) 1.24
Current understanding of SPEM and its standing in the preneoplastic process. Gastric Cancer (2010) 1.22
Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells. Dev Cell (2002) 1.22
Rab11a-dependent exocytosis of discoidal/fusiform vesicles in bladder umbrella cells. Proc Natl Acad Sci U S A (2008) 1.20
Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis. Mol Cell Proteomics (2008) 1.18
Protein LidA from Legionella is a Rab GTPase supereffector. Proc Natl Acad Sci U S A (2011) 1.18
Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25. Mol Biol Cell (2012) 1.15
High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA. EMBO Rep (2010) 1.14
Efficacy of cetuximab in the treatment of Menetrier's disease. Sci Transl Med (2009) 1.14
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1. EMBO J (2011) 1.14
Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins. EMBO J (2012) 1.14
Evidence for repatterning of the gastric fundic epithelium associated with Ménétrier's disease and TGFalpha overexpression. Gastroenterology (2005) 1.14
Expression of Pdx-1 in human gastric metaplasia and gastric adenocarcinoma. Hum Pathol (2006) 1.14
Dynamics of the apical plasma membrane recycling system during cell division. Traffic (2003) 1.13
Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression. Gut (2012) 1.13
Spasmolytic polypeptide-expressing metaplasia (SPEM) associated with gastric cancer in Iceland. Dig Dis Sci (2003) 1.13
Pak1 and PIX regulate contact inhibition during epithelial wound healing. EMBO J (2003) 1.12
Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. Exp Cell Res (2008) 1.11
Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia. Gastroenterology (2008) 1.11
Rab11-FIP1C and Rab14 direct plasma membrane sorting and particle incorporation of the HIV-1 envelope glycoprotein complex. PLoS Pathog (2013) 1.11
Catalytic mechanism of a mammalian Rab·RabGAP complex in atomic detail. Proc Natl Acad Sci U S A (2012) 1.09
The role of syntaxins in the specificity of vesicle targeting in polarized epithelial cells. Mol Biol Cell (2005) 1.09
AKAP350 at the Golgi apparatus. I. Identification of a distinct Golgi apparatus targeting motif in AKAP350. J Biol Chem (2002) 1.06
D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling. J Biol Chem (2009) 1.06
Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin. Mol Biol Cell (2004) 1.04
CLIC4 is enriched at cell-cell junctions and colocalizes with AKAP350 at the centrosome and midbody of cultured mammalian cells. Cell Motil Cytoskeleton (2003) 1.04