Published in J Cell Biol on May 17, 2010
A molecular network for de novo generation of the apical surface and lumen. Nat Cell Biol (2010) 3.70
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Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Curr Biol (2010) 1.86
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Regulation of asymmetric cell division in the epidermis. Cell Div (2011) 0.83
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Protein adaptation: mitotic functions for membrane trafficking proteins. Nat Rev Mol Cell Biol (2013) 0.81
Opening ahead: early steps in lumen formation revealed. Nat Cell Biol (2010) 0.80
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PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position. J Cell Sci (2016) 0.78
Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor. J Virol (2016) 0.76
ITSN2L Interacts with and Negatively Regulates RABEP1. Int J Mol Sci (2015) 0.76
Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development. J Cell Sci (2015) 0.76
Homeostatic imbalance in epithelial ducts and its role in carcinogenesis. Scientifica (Cairo) (2012) 0.76
ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture. J Cell Sci (2016) 0.76
How to Train a Cell-Cutting-Edge Molecular Tools. Front Chem (2017) 0.75
Mitotic Spindle Positioning in the EMS Cell of Caenorhabditis elegans Requires LET-99 and LIN-5/NuMA. Genetics (2016) 0.75
Rab14 specifies the apical membrane through Arf6-mediated regulation of lipid domains and Cdc42. Sci Rep (2016) 0.75
The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesion. Nat Commun (2014) 0.75
ERα-mediated repression of pro-inflammatory cytokine expression by glucocorticoids reveals a crucial role for TNFα and IL1α in lumen formation and maintenance. J Cell Sci (2012) 0.75
Endocytic turnover of Rab8 controls cell polarization. J Cell Sci (2017) 0.75
Cell adhesion controlled by adhesion G-protein coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising Intersectins and Elmo/Dock. J Biol Chem (2017) 0.75
Mitochondria chaperone GRP75 moonlighting as a cell cycle controller to derail endocytosis provides an opportunity for nanomicrosphere intracellular delivery. Oncotarget (2017) 0.75
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From cells to organs: building polarized tissue. Nat Rev Mol Cell Biol (2008) 5.06
Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells. Cell (2005) 4.86
Cdc42--the centre of polarity. J Cell Sci (2004) 4.51
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol Cell Biol (2002) 4.50
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Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly. Nat Cell Biol (2001) 4.08
Activity of Rho-family GTPases during cell division as visualized with FRET-based probes. J Cell Biol (2003) 3.85
Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell (2004) 3.52
A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells. Cell (2006) 3.38
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis. J Cell Biol (2008) 3.29
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Direct interaction of two polarity complexes implicated in epithelial tight junction assembly. Nat Cell Biol (2003) 3.07
Crosstalk between small GTPases and polarity proteins in cell polarization. Nat Rev Mol Cell Biol (2008) 3.05
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EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP. Nat Neurosci (2002) 2.90
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A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. Nat Cell Biol (2001) 2.73
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Clathrin is required for the function of the mitotic spindle. Nature (2005) 2.45
Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium. Nat Neurosci (2007) 2.33
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Cdc42-dependent modulation of tight junctions and membrane protein traffic in polarized Madin-Darby canine kidney cells. Mol Biol Cell (2001) 1.51
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The formin INF2 regulates basolateral-to-apical transcytosis and lumen formation in association with Cdc42 and MAL2. Dev Cell (2010) 1.83
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MARVEL: a conserved domain involved in membrane apposition events. Trends Biochem Sci (2002) 1.71
Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis. Mol Biol Cell (2007) 1.62
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Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nat Cell Biol (2012) 1.42
Polarity proteins PAR6 and aPKC regulate cell death through GSK-3beta in 3D epithelial morphogenesis. J Cell Sci (2007) 1.42
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MAL expression in lymphoid cells: further evidence for MAL as a distinct molecular marker of primary mediastinal large B-cell lymphomas. Mod Pathol (2002) 1.34
MAL2, a novel raft protein of the MAL family, is an essential component of the machinery for transcytosis in hepatoma HepG2 cells. J Cell Biol (2002) 1.34
Disruption of apical-basal polarity of human embryonic stem cells enhances hematoendothelial differentiation. Stem Cells (2007) 1.30
Caveolin-1 and MAL are located on prostasomes secreted by the prostate cancer PC-3 cell line. J Cell Sci (2004) 1.30
Identification of genes involved in resistance to interferon-alpha in cutaneous T-cell lymphoma. Am J Pathol (2002) 1.29
Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors OCT-2, BOB.1, and PU.1 in the absence of immunoglobulins. Am J Pathol (2003) 1.27
Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane. J Cell Biol (2007) 1.26
A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor. Nat Cell Biol (2010) 1.25
MAL gene expression in esophageal cancer suppresses motility, invasion and tumorigenicity and enhances apoptosis through the Fas pathway. Oncogene (2003) 1.19
Microarray analysis of early stage serous ovarian cancers shows profiles predictive of favorable outcome. Clin Cancer Res (2009) 1.16
Epithelial cell polarity alters Rho-GTPase responses to Pseudomonas aeruginosa. Mol Biol Cell (2003) 1.14
Long-term culture of hepatic progenitors derived from mouse Dlk+ hepatoblasts. J Cell Sci (2004) 1.14
Polarity in mammalian epithelial morphogenesis. Cold Spring Harb Perspect Biol (2013) 1.14
Cell confinement controls centrosome positioning and lumen initiation during epithelial morphogenesis. J Cell Biol (2012) 1.13
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Recruitment of transferrin receptor to immunological synapse in response to TCR engagement. J Immunol (2004) 1.12
Electrode-free picoinjection of microfluidic drops. Lab Chip (2012) 1.12
Regulated vesicle fusion generates signaling nanoterritories that control T cell activation at the immunological synapse. J Exp Med (2013) 1.12
Hypermethylated MAL gene - a silent marker of early colon tumorigenesis. J Transl Med (2008) 1.11
Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes. Clin Cancer Res (2006) 1.09
Large-scale quantitative LC-MS/MS analysis of detergent-resistant membrane proteins from rat renal collecting duct. Am J Physiol Cell Physiol (2008) 1.09
Pseudomonas aeruginosa-mediated damage requires distinct receptors at the apical and basolateral surfaces of the polarized epithelium. Infect Immun (2009) 1.09
Phosphoinositides control epithelial development. Cell Cycle (2007) 1.05
MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cells. Blood (2008) 1.05
Lipid rafts mediate biosynthetic transport to the T lymphocyte uropod subdomain and are necessary for uropod integrity and function. Blood (2002) 1.05
Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy. Mol Cancer Res (2009) 1.03
Divide and polarize: recent advances in the molecular mechanism regulating epithelial tubulogenesis. Curr Opin Cell Biol (2011) 1.03
Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. Dev Biol (2011) 1.02
The Caenorhabditis elegans nuclear receptor gene nhr-25 regulates epidermal cell development. Mol Cell Biol (2004) 1.01
INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells. J Cell Biol (2012) 1.01
Rac1 is required for reorientation of polarity and lumen formation through a PI 3-kinase-dependent pathway. Am J Physiol Renal Physiol (2007) 0.98
Cse1l is a negative regulator of CFTR-dependent fluid secretion. Curr Biol (2010) 0.96
MAL regulates clathrin-mediated endocytosis at the apical surface of Madin-Darby canine kidney cells. J Cell Biol (2003) 0.96
Features of influenza HA required for apical sorting differ from those required for association with DRMs or MAL. Traffic (2003) 0.96
MDCK cystogenesis driven by cell stabilization within computational analogues. PLoS Comput Biol (2011) 0.96
p120 catenin is required for normal renal tubulogenesis and glomerulogenesis. Development (2011) 0.96
EGFR controls IQGAP basolateral membrane localization and mitotic spindle orientation during epithelial morphogenesis. EMBO J (2014) 0.96
Expression of MAL2, an integral protein component of the machinery for basolateral-to-apical transcytosis, in human epithelia. J Histochem Cytochem (2004) 0.95
Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis. Hepatology (2004) 0.95
Vesicle transport, cilium formation, and membrane specialization: the origins of a sensory organelle. Proc Natl Acad Sci U S A (2006) 0.94
Expression of MAL, an integral protein component of the machinery for raft-mediated pical transport, in human epithelia. J Histochem Cytochem (2003) 0.94
Full Poincaré beams. Opt Express (2010) 0.94
An essential role for the MAL protein in targeting Lck to the plasma membrane of human T lymphocytes. J Exp Med (2008) 0.93
Protein 4.1R regulates cell migration and IQGAP1 recruitment to the leading edge. J Cell Sci (2011) 0.93
The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1. J Biol Chem (2002) 0.92
Pseudomonas aeruginosa interacts with epithelial cells rapidly forming aggregates that are internalized by a Lyn-dependent mechanism. Cell Microbiol (2011) 0.92
A computational approach to understand in vitro alveolar morphogenesis. PLoS One (2009) 0.90
A computational approach to resolve cell level contributions to early glandular epithelial cancer progression. BMC Syst Biol (2009) 0.90
Developmental biology: the hole picture. Nature (2006) 0.89
Mucosa-associated lymphoid tissue lymphoma of the thymus: a case report with no evidence of MALT1 rearrangement. Virchows Arch (2005) 0.89
Paraxial and nonparaxial polynomial beams and the analytic approach to propagation. Opt Lett (2011) 0.88
Dynamics of MAL2 during glycosylphosphatidylinositol-anchored protein transcytotic transport to the apical surface of hepatoma HepG2 cells. Traffic (2006) 0.88
Formin INF2 regulates MAL-mediated transport of Lck to the plasma membrane of human T lymphocytes. Blood (2010) 0.88
Computational investigation of epithelial cell dynamic phenotype in vitro. Theor Biol Med Model (2009) 0.88
Loss of MAL expression in precancerous lesions of the esophagus. Ann Surg Oncol (2006) 0.87
MAL facilitates the incorporation of exocytic uroplakin-delivering vesicles into the apical membrane of urothelial umbrella cells. Mol Biol Cell (2012) 0.87
MAL is expressed in a subset of Hodgkin lymphoma and identifies a population of patients with poor prognosis. Am J Clin Pathol (2006) 0.87
Mucin 1 (MUC1) is a novel partner for MAL2 in breast carcinoma cells. BMC Cell Biol (2009) 0.86
Daxx functions as a scaffold of a protein assembly constituted by GLUT4, JNK1 and KIF5B. J Cell Physiol (2009) 0.86
Focal adhesion components are essential for mammalian cell cytokinesis. Cell Cycle (2008) 0.86
MYADM regulates Rac1 targeting to ordered membranes required for cell spreading and migration. Mol Biol Cell (2011) 0.83
Imaging the polarization of a light field. Opt Express (2013) 0.83
Mechanical control of epithelial lumen formation. Small GTPases (2013) 0.83
Formation of multicellular epithelial structures. Novartis Found Symp (2005) 0.83
MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression. Mol Biol Cell (2012) 0.83
Plitidepsin cellular binding and Rac1/JNK pathway activation depend on membrane cholesterol content. Mol Pharmacol (2006) 0.82
Expression and distribution of MAL2, an essential element of the machinery for basolateral-to-apical transcytosis, in human thyroid epithelial cells. Endocrinology (2003) 0.82
Protein 4.1R binds to CLASP2 and regulates dynamics, organization and attachment of microtubules to the cell cortex. J Cell Sci (2013) 0.82
MAL protein controls protein sorting at the supramolecular activation cluster of human T lymphocytes. J Immunol (2011) 0.82
Development: inflationary pressures. Nature (2007) 0.79
Simulation of lung alveolar epithelial wound healing in vitro. J R Soc Interface (2010) 0.79