Published in Mol Biol Evol on February 25, 2011
Quantitative liquid chromatography-mass spectrometry-multiple reaction monitoring (LC-MS-MRM) analysis of site-specific glycoforms of haptoglobin in liver disease. Mol Cell Proteomics (2013) 1.11
Protein abundance is key to distinguish promiscuous from functional phosphorylation based on evolutionary information. Philos Trans R Soc Lond B Biol Sci (2012) 0.92
Genomics and epigenomics of the human glycome. Glycoconj J (2012) 0.90
Proteome-wide analysis of single-nucleotide variations in the N-glycosylation sequon of human genes. PLoS One (2012) 0.89
Structure-based comparative analysis and prediction of N-linked glycosylation sites in evolutionarily distant eukaryotes. Genomics Proteomics Bioinformatics (2013) 0.86
Human germline and pan-cancer variomes and their distinct functional profiles. Nucleic Acids Res (2014) 0.84
N-Glycosylation of Human R-Spondin 1 Is Required for Efficient Secretion and Stability but Not for Its Heparin Binding Ability. Int J Mol Sci (2016) 0.76
Identification of Novel N-Glycosylation Sites at Noncanonical Protein Consensus Motifs. J Proteome Res (2016) 0.75
Distribution bias analysis of germline and somatic single-nucleotide variations that impact protein functional site and neighboring amino acids. Sci Rep (2017) 0.75
MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res (2004) 168.89
A tissue-specific atlas of mouse protein phosphorylation and expression. Cell (2010) 8.65
Glycosylation in cellular mechanisms of health and disease. Cell (2006) 8.45
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science (2009) 5.37
Precision mapping of an in vivo N-glycoproteome reveals rigid topological and sequence constraints. Cell (2010) 3.60
Genetic defects in the human glycome. Nat Rev Genet (2006) 3.59
N-Glycans in cancer progression. Glycobiology (2008) 2.35
Impacts of gene essentiality, expression pattern, and gene compactness on the evolutionary rate of mammalian proteins. Mol Biol Evol (2006) 2.22
Weak functional constraints on phosphoproteomes. Trends Genet (2009) 2.10
Assessing the impact of secondary structure and solvent accessibility on protein evolution. Genetics (1998) 2.05
Minimotif Miner: a tool for investigating protein function. Nat Methods (2006) 1.92
Mutations in PMM2 that cause congenital disorders of glycosylation, type Ia (CDG-Ia). Hum Mutat (2000) 1.48
Non-functional phosphorylations? Trends Biochem Sci (2008) 1.46
Solvent accessibility and purifying selection within proteins of Escherichia coli and Salmonella enterica. Mol Biol Evol (2000) 1.43
Linear regression models for solvent accessibility prediction in proteins. J Comput Biol (2005) 1.42
Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis. Immunity (2007) 1.33
Glycosylation diseases: quo vadis? Biochim Biophys Acta (2008) 1.30
Proportion of solvent-exposed amino acids in a protein and rate of protein evolution. Mol Biol Evol (2007) 1.23
Congenital disorders of glycosylation. Annu Rev Genomics Hum Genet (2001) 1.21
Congenital disorder of glycosylation type Ia (CDG-Ia): phenotypic spectrum of the R141H/F119L genotype. Arch Dis Child (2001) 1.16
Carbohydrate-deficient glycoprotein syndromes: peculiar group of new disorders. Pediatr Neurol (1993) 1.10
Moving from transcriptional to phospho-evolution: generalizing regulatory evolution? Trends Genet (2010) 1.08
Phosphorylated and nonphosphorylated serine and threonine residues evolve at different rates in mammals. Mol Biol Evol (2010) 1.06
A point mutation creating an extra N-glycosylation site in fibrillin-1 results in neonatal Marfan syndrome. Genomics (1996) 0.98
Molecular evolution and network-level analysis of the N-glycosylation metabolic pathway across primates. Mol Biol Evol (2010) 0.95
Rapid subfunctionalization accompanied by prolonged and substantial neofunctionalization in duplicate gene evolution. Genetics (2005) 3.98
Evolutionary conservation of expression profiles between human and mouse orthologous genes. Mol Biol Evol (2005) 3.62
Gene sequence-based criteria for identification of new rickettsia isolates and description of Rickettsia heilongjiangensis sp. nov. J Clin Microbiol (2003) 3.59
The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms. Nat Rev Genet (2011) 3.57
Why do hubs tend to be essential in protein networks? PLoS Genet (2006) 3.29
Gene losses during human origins. PLoS Biol (2006) 3.17
RNA sequencing shows no dosage compensation of the active X-chromosome. Nat Genet (2010) 2.71
Null mutations in human and mouse orthologs frequently result in different phenotypes. Proc Natl Acad Sci U S A (2008) 2.60
Balanced codon usage optimizes eukaryotic translational efficiency. PLoS Genet (2012) 2.32
Impacts of gene essentiality, expression pattern, and gene compactness on the evolutionary rate of mammalian proteins. Mol Biol Evol (2006) 2.22
Genomic patterns of pleiotropy and the evolution of complexity. Proc Natl Acad Sci U S A (2010) 2.19
Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks. Nat Genet (2010) 2.16
Mouse duplicate genes are as essential as singletons. Trends Genet (2007) 2.12
More genes underwent positive selection in chimpanzee evolution than in human evolution. Proc Natl Acad Sci U S A (2007) 2.00
Low rates of expression profile divergence in highly expressed genes and tissue-specific genes during mammalian evolution. Mol Biol Evol (2006) 1.97
Dramatic variation of the vomeronasal pheromone receptor gene repertoire among five orders of placental and marsupial mammals. Proc Natl Acad Sci U S A (2005) 1.88
Toward a molecular understanding of pleiotropy. Genetics (2006) 1.88
Comparative genomic analysis identifies an evolutionary shift of vomeronasal receptor gene repertoires in the vertebrate transition from water to land. Genome Res (2007) 1.85
Adaptive diversification of bitter taste receptor genes in Mammalian evolution. Mol Biol Evol (2003) 1.82
Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes. Mol Biol Evol (2005) 1.77
Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells. Int J Cancer (2006) 1.76
The hearing gene Prestin unites echolocating bats and whales. Curr Biol (2010) 1.62
Higher duplicability of less important genes in yeast genomes. Mol Biol Evol (2005) 1.57
Pseudogenization of the umami taste receptor gene Tas1r1 in the giant panda coincided with its dietary switch to bamboo. Mol Biol Evol (2010) 1.53
Maintenance of duplicate genes and their functional redundancy by reduced expression. Trends Genet (2010) 1.51
Composition and evolution of the V2r vomeronasal receptor gene repertoire in mice and rats. Genomics (2005) 1.47
Impact of gene expression noise on organismal fitness and the efficacy of natural selection. Proc Natl Acad Sci U S A (2011) 1.46
The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories. Genomics (2005) 1.43
Sex-specific splicing of the honeybee doublesex gene reveals 300 million years of evolution at the bottom of the insect sex-determination pathway. Genetics (2007) 1.43
Gene complexity and gene duplicability. Curr Biol (2005) 1.42
Relaxation of selective constraint and loss of function in the evolution of human bitter taste receptor genes. Hum Mol Genet (2004) 1.38
In search of the biological significance of modular structures in protein networks. PLoS Comput Biol (2007) 1.38
The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep (2012) 1.36
Evolution of the sweet taste receptor gene Tas1r2 in bats. Mol Biol Evol (2010) 1.36
Impact of translational error-induced and error-free misfolding on the rate of protein evolution. Mol Syst Biol (2010) 1.35
Origin of the genetic components of the vomeronasal system in the common ancestor of all extant vertebrates. Mol Biol Evol (2008) 1.33
Measuring the evolutionary rate of protein-protein interaction. Proc Natl Acad Sci U S A (2011) 1.32
MicroRNA let-7c inhibits migration and invasion of human non-small cell lung cancer by targeting ITGB3 and MAP4K3. Cancer Lett (2013) 1.31
Positive selection for elevated gene expression noise in yeast. Mol Syst Biol (2009) 1.30
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly. Proc Natl Acad Sci U S A (2012) 1.29
Genomic and genetic evidence for the loss of umami taste in bats. Genome Biol Evol (2011) 1.27
Did brain-specific genes evolve faster in humans than in chimpanzees? Trends Genet (2006) 1.26
Positive selection on protein-length in the evolution of a primate sperm ion channel. Proc Natl Acad Sci U S A (2003) 1.26
Abundant indispensable redundancies in cellular metabolic networks. Genome Biol Evol (2009) 1.23
Gene dosage and gene duplicability. Genetics (2008) 1.23
Expression reduction in mammalian X chromosome evolution refutes Ohno's hypothesis of dosage compensation. Proc Natl Acad Sci U S A (2012) 1.22
Rapid turnover and species-specificity of vomeronasal pheromone receptor genes in mice and rats. Gene (2004) 1.21
p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR. Mol Cancer Ther (2008) 1.21
Genomic evidence for elevated mutation rates in highly expressed genes. EMBO Rep (2012) 1.19
Largest vertebrate vomeronasal type 1 receptor gene repertoire in the semiaquatic platypus. Mol Biol Evol (2007) 1.19
Why are some human disease-associated mutations fixed in mice? Trends Genet (2003) 1.19
Why is the correlation between gene importance and gene evolutionary rate so weak? PLoS Genet (2009) 1.16
On the definition and measurement of pleiotropy. Trends Genet (2013) 1.14
Distinct evolutionary patterns between chemoreceptors of 2 vertebrate olfactory systems and the differential tuning hypothesis. Mol Biol Evol (2008) 1.13
No gene-specific optimization of mutation rate in Escherichia coli. Mol Biol Evol (2013) 1.13
Coexpression of linked genes in Mammalian genomes is generally disadvantageous. Mol Biol Evol (2008) 1.12
Nonneutral evolution of the transcribed pseudogene Makorin1-p1 in mice. Mol Biol Evol (2004) 1.11
Neuronal protein synuclein gamma predicts poor clinical outcome in breast cancer. Int J Cancer (2007) 1.10
Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly. Proc Natl Acad Sci U S A (2013) 1.09
Diet shapes the evolution of the vertebrate bitter taste receptor gene repertoire. Mol Biol Evol (2013) 1.08
Positive selection for indel substitutions in the rodent sperm protein catsper1. Mol Biol Evol (2005) 1.07
Contrasting genetic paths to morphological and physiological evolution. Proc Natl Acad Sci U S A (2010) 1.05
Evolution of the complementary sex-determination gene of honey bees: balancing selection and trans-species polymorphisms. Genome Res (2006) 1.04
The ortholog conjecture is untestable by the current gene ontology but is supported by RNA sequencing data. PLoS Comput Biol (2012) 1.02
Impact of extracellularity on the evolutionary rate of mammalian proteins. Genome Biol Evol (2010) 1.02
Generation of novel monoclonal antibodies and their application for detecting ARD1 expression in colorectal cancer. Cancer Lett (2008) 1.02
High expression hampers horizontal gene transfer. Genome Biol Evol (2012) 1.01
Evaluation of transovarial transmission and transmissibility of Ehrlichia chaffeensis (Rickettsiales: Anaplasmataceae) in Amblyomma americanum (Acari: Ixodidae). J Med Entomol (2003) 1.01
Suppression of tumor growth and metastasis by a VEGFR-1 antagonizing peptide identified from a phage display library. Int J Cancer (2004) 1.01
Remarkable expansions of an X-linked reproductive homeobox gene cluster in rodent evolution. Genomics (2006) 1.00
Evolutionary dynamics of nematode operons: easy come, slow go. Genome Res (2008) 1.00
Protein subcellular relocalization in the evolution of yeast singleton and duplicate genes. Genome Biol Evol (2009) 0.99
Human coding RNA editing is generally nonadaptive. Proc Natl Acad Sci U S A (2014) 0.96
Zebrafish ribonucleases are bactericidal: implications for the origin of the vertebrate RNase A superfamily. Mol Biol Evol (2007) 0.95
Rapid evolution of mammalian X-linked testis-expressed homeobox genes. Genetics (2004) 0.93
Evidence for escape from adaptive conflict? Nature (2009) 0.91
Diagnosis of gastric cancer using decision tree classification of mass spectral data. Cancer Sci (2007) 0.90
Origin and evolution of the vertebrate vomeronasal system viewed through system-specific genes. Bioessays (2006) 0.90
A big world inside small-world networks. PLoS One (2009) 0.90
Widespread losses of vomeronasal signal transduction in bats. Mol Biol Evol (2010) 0.89
Processed pseudogenes: the 'fossilized footprints' of past gene expression. Trends Genet (2009) 0.89
Ancient expansion of the ribonuclease A superfamily revealed by genomic analysis of placental and marsupial mammals. Gene (2006) 0.88
Genetic evidence for the coexistence of pheromone perception and full trichromatic vision in howler monkeys. Mol Biol Evol (2004) 0.85
Mismatches between feeding ecology and taste receptor evolution: an inconvenient truth. Proc Natl Acad Sci U S A (2012) 0.85
Elevated maspin expression is associated with better overall survival in esophageal squamous cell carcinoma (ESCC). PLoS One (2013) 0.84
Transcriptional reprogramming and backup between duplicate genes: is it a genomewide phenomenon? Genetics (2005) 0.84
Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity. Microbes Infect (2010) 0.84
Positive selection, not negative selection, in the pseudogenization of rcsA in Yersinia pestis. Proc Natl Acad Sci U S A (2008) 0.83
Isolation, characterization, and evolutionary divergence of mouse RNase 6: evidence for unusual evolution in rodents. J Mol Evol (2004) 0.83
IL1 receptor antagonist gene IL1-RN variable number of tandem repeats polymorphism and cancer risk: a literature review and meta-analysis. PLoS One (2012) 0.82
Rapid evolution of primate ESX1, an X-linked placenta- and testis-expressed homeobox gene. Hum Mol Genet (2007) 0.82
Preparation and characterization of monoclonal antibodies against nucleostemin, a protein that controls cell proliferation in stem cells and cancer cells. Hybridoma (Larchmt) (2005) 0.81
Accelerated evolution and loss of a domain of the sperm-egg-binding protein SED1 in ancestral primates. Mol Biol Evol (2006) 0.80
Phylogenetic evidence for parallel adaptive origins of digestive RNases in Asian and African leaf monkeys: a response to Xu et al. (2009). Mol Phylogenet Evol (2009) 0.79
Why are genes encoded on the lagging strand of the bacterial genome? Genome Biol Evol (2013) 0.79
Toward genome-wide identification of Bateson-Dobzhansky-Muller incompatibilities in yeast: a simulation study. Genome Biol Evol (2013) 0.78
On the growth of scientific knowledge: yeast biology as a case study. PLoS Comput Biol (2009) 0.78
The microevolution of V1r vomeronasal receptor genes in mice. Genome Biol Evol (2011) 0.77
A panorama of mammalian gene expression evolution. Mol Syst Biol (2011) 0.76
Erratic evolution of SRY in higher primates. Mol Biol Evol (2002) 0.76