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1
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Apoptotic mechanisms after cerebral ischemia.
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2009
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3.92
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2
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Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets.
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Nat Rev Drug Discov
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2011
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3.08
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3
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Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice.
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Am J Physiol Heart Circ Physiol
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2009
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2.00
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4
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NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries.
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Circ Res
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2005
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1.65
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5
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Angiotensin II type 2 receptor stimulation initiated after stroke causes neuroprotection in conscious rats.
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Hypertension
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2012
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1.61
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6
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Targeting Rho and Rho-kinase in the treatment of cardiovascular disease.
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Trends Pharmacol Sci
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2005
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1.60
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7
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NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition.
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Pharmacol Ther
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2008
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1.58
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8
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Pathophysiology, treatment, and animal and cellular models of human ischemic stroke.
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Mol Neurodegener
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2011
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1.48
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9
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Evidence for a detrimental role of TLR8 in ischemic stroke.
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Exp Neurol
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2013
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1.46
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10
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Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide.
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2010
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11
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Oxidative stress and endothelial dysfunction in cerebrovascular disease.
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Front Biosci (Landmark Ed)
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2011
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1.34
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12
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Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries.
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Am J Physiol Heart Circ Physiol
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2010
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1.29
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13
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Adiponectin receptor signalling in the brain.
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Br J Pharmacol
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2012
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1.28
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14
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Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus.
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Nat Med
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2012
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1.23
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15
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Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia.
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J Cereb Blood Flow Metab
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2012
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1.22
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NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival.
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Naunyn Schmiedebergs Arch Pharmacol
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2009
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1.15
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17
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Effect of gender on NADPH-oxidase activity, expression, and function in the cerebral circulation: role of estrogen.
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Stroke
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2007
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1.13
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18
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Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo.
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Stroke
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2004
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1.11
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19
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NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2.
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Am J Physiol Heart Circ Physiol
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2008
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1.10
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20
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Recent evidence for an involvement of rho-kinase in cerebral vascular disease.
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Stroke
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2006
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1.08
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21
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Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.
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Mol Pharmacol
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2011
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1.04
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22
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Effect of gender and sex hormones on vascular oxidative stress.
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Clin Exp Pharmacol Physiol
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2007
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1.02
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23
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NADPH oxidases as regulators of tumor angiogenesis: current and emerging concepts.
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Antioxid Redox Signal
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2012
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1.02
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24
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Flow-induced cerebral vasodilatation in vivo involves activation of phosphatidylinositol-3 kinase, NADPH-oxidase, and nitric oxide synthase.
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J Cereb Blood Flow Metab
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2006
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1.02
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25
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Evidence that nitric oxide inhibits vascular inflammation and superoxide production via a p47phox-dependent mechanism in mice.
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Clin Exp Pharmacol Physiol
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2009
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1.01
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26
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Chemokine-related gene expression in the brain following ischemic stroke: no role for CXCR2 in outcome.
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Brain Res
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2010
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1.00
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27
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Inwardly rectifying potassium channels in the regulation of vascular tone.
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Curr Drug Targets
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2003
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1.00
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28
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Novel isoforms of NADPH-oxidase in cerebral vascular control.
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Pharmacol Ther
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2006
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0.99
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29
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Reactive oxygen species in the cerebral circulation: are they all bad?
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Antioxid Redox Signal
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2006
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0.99
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30
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NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke.
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Brain Res
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2006
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0.98
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31
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Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone/salt-mediated cardiac remodeling and vascular reactivity but not blood pressure.
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Hypertension
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2014
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0.97
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32
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Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain.
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J Appl Physiol (1985)
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2012
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0.97
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33
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Gender influences cerebral vascular responses to angiotensin II through Nox2-derived reactive oxygen species.
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Stroke
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2009
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0.97
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34
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Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models.
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Redox Rep
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2010
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0.97
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35
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Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke.
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Brain Res
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2009
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0.97
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36
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Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo.
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Stroke
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2004
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0.96
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37
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Vasorelaxant and antioxidant activity of the isoflavone metabolite equol in carotid and cerebral arteries.
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Brain Res
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2007
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0.95
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38
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Segmental differences in the roles of rho-kinase and protein kinase C in mediating vasoconstriction.
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J Pharmacol Exp Ther
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2006
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0.95
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39
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Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia.
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Stroke
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2010
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0.94
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40
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Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke.
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PLoS One
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2011
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0.94
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41
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Pathogenesis of acute stroke and the role of inflammasomes.
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Ageing Res Rev
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2013
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0.94
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42
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Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice.
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Hypertension
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2012
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0.93
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43
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Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice.
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Am J Physiol Regul Integr Comp Physiol
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2004
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0.92
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44
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Cerebral vascular effects of reactive oxygen species: recent evidence for a role of NADPH-oxidase.
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Clin Exp Pharmacol Physiol
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2003
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0.92
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45
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Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights.
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Curr Med Chem
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2007
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0.91
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46
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Post-stroke inflammation and the potential efficacy of novel stem cell therapies: focus on amnion epithelial cells.
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Front Cell Neurosci
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2013
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0.91
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47
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NADPH-induced contractions of mouse aorta do not involve NADPH oxidase: a role for P2X receptors.
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J Pharmacol Exp Ther
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2006
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0.90
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48
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Nitroxyl (HNO) as a vasoprotective signaling molecule.
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Antioxid Redox Signal
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2010
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0.90
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49
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Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways.
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J Neurochem
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2012
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0.89
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50
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Vascular cognitive impairment and Alzheimer's disease: role of cerebral hypoperfusion and oxidative stress.
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Naunyn Schmiedebergs Arch Pharmacol
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2012
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0.89
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51
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Evidence that the EphA2 receptor exacerbates ischemic brain injury.
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PLoS One
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2013
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0.89
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52
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Sex-dependent effects of G protein-coupled estrogen receptor activity on outcome after ischemic stroke.
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Stroke
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2014
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0.88
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53
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Vascular dysfunction in cerebrovascular disease: mechanisms and therapeutic intervention.
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Clin Sci (Lond)
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2010
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0.88
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54
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Inhibitory effects of protein kinase C on inwardly rectifying K+- and ATP-sensitive K+ channel-mediated responses of the basilar artery.
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Stroke
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2002
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0.86
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55
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A flow cytometric method for the analysis of macrophages in the vascular wall.
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J Immunol Methods
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2013
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0.86
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56
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Reactive oxygen species in the cerebral circulation: physiological roles and therapeutic implications for hypertension and stroke.
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Drugs
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2004
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0.84
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57
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Stroke increases g protein-coupled estrogen receptor expression in the brain of male but not female mice.
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Neurosignals
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2012
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0.83
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58
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Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression.
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Brain Res
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2012
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0.83
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59
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Chronic aldosterone administration causes Nox2-mediated increases in reactive oxygen species production and endothelial dysfunction in the cerebral circulation.
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J Hypertens
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2014
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0.82
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60
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Opposing roles of endothelial and smooth muscle phosphatidylinositol 3-kinase in vasoconstriction: effects of rho-kinase and hypertension.
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J Pharmacol Exp Ther
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2005
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0.82
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61
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Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress.
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PLoS One
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2013
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62
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Aldosterone and the mineralocorticoid receptor in the cerebral circulation and stroke.
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Exp Transl Stroke Med
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2012
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63
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Vasorelaxant and antiaggregatory actions of the nitroxyl donor isopropylamine NONOate are maintained in hypercholesterolemia.
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Am J Physiol Heart Circ Physiol
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2011
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64
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Influence of gender on K+-induced cerebral vasodilatation.
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2004
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Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain.
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Ann Neurol
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2015
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Vascular rho kinases and their potential therapeutic applications.
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Curr Opin Drug Discov Devel
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2007
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67
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Ghrelin-related peptides exert protective effects in the cerebral circulation of male mice through a nonclassical ghrelin receptor(s).
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Endocrinology
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2015
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0.79
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68
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Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice.
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Naunyn Schmiedebergs Arch Pharmacol
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2011
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0.78
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69
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The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity.
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Naunyn Schmiedebergs Arch Pharmacol
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2010
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0.78
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NOX2β: A novel splice variant of NOX2 that regulates NADPH oxidase activity in macrophages.
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PLoS One
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2012
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71
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Chlamydia pneumoniae induces a pro-inflammatory phenotype in murine vascular smooth muscle cells independently of elevating reactive oxygen species.
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Clin Exp Pharmacol Physiol
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2012
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72
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Calsenilin contributes to neuronal cell death in ischemic stroke.
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Brain Pathol
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2012
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73
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Nitroxyl (HNO) suppresses vascular Nox2 oxidase activity.
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Free Radic Biol Med
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2013
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0.77
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74
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Over-expression of DSCR1 protects against post-ischemic neuronal injury.
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PLoS One
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2012
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Neurogenic atherosclerosis mediated by neuropeptide y: hardening of the evidence.
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Arterioscler Thromb Vasc Biol
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2003
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Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1.
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Naunyn Schmiedebergs Arch Pharmacol
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2013
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Signalling pathways activated by hydrogen peroxide in vascular smooth muscle.
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J Hypertens
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Neuronal NO mediates cerebral vasodilator responses to K+ in hypertensive rats.
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2002
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Angiotensin (1-7) as a therapy to prevent rupture of intracranial aneurysms?
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Hypertension
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2014
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Radicals spark interest in cerebral vasodilator mechanisms. Focus on "TNF-alpha dilates cerebral arteries via NAD(P)H oxidase-dependent Ca2+ spark activation".
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Am J Physiol Cell Physiol
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2006
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Reduced cerebrovascular remodeling and functional impairment in spontaneously hypertensive rats following combined treatment with suboptimal doses of telmisartan and ramipril: is less really more?
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J Hypertens
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Maternal nicotine exposure and fetal programming of vascular oxidative stress in adult offspring.
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Corrigendum: Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus.
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Nat Med
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2016
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0.75
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