Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor.

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Published in Mol Pharmacol on March 03, 2011

Authors

Terrance D Barrett1, Heather L Palomino, Theresa I Brondstetter, Kimon C Kanelakis, Xiaodong Wu, Peter V Haug, Wen Yan, Andrew Young, Hong Hua, Juliet C Hart, Da-Thao Tran, Hariharan Venkatesan, Mark D Rosen, Hillary M Peltier, Kia Sepassi, Michele C Rizzolio, Scott D Bembenek, Tara Mirzadegan, Michael H Rabinowitz, Nigel P Shankley

Author Affiliations

1: Cardiovascular Metabolic Research, Johnson and Johnson Pharmaceutical Research and Development LLC, 3210 Merryfield Row, San Diego, CA 92121, USA. tbarret1@its.jnj.com

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