R B Vallee

Author PubWeight™ 176.24‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J Cell Biol 1996 7.65
2 Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J Cell Biol 1997 6.57
3 A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nat Cell Biol 2000 5.29
4 Retrograde transport by the microtubule-associated protein MAP 1C. Nature 1987 5.06
5 Effects of mutant rat dynamin on endocytosis. J Cell Biol 1993 5.05
6 A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs). J Cell Biol 1982 4.94
7 MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties. J Cell Biol 1987 4.78
8 Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis. Nature 1991 4.69
9 Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued. J Cell Biol 1995 4.66
10 Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins. Nature 1990 4.30
11 Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules. Cell 1989 3.97
12 DYNEINS: molecular structure and cellular function. Annu Rev Cell Biol 1994 3.26
13 Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature 1991 2.99
14 An extended microtubule-binding structure within the dynein motor domain. Nature 1997 2.93
15 Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin. J Biol Chem 1993 2.91
16 Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization. Curr Biol 2001 2.89
17 Mutations in the tail domain of DYNC1H1 cause dominant spinal muscular atrophy. Neurology 2012 2.56
18 DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast. J Cell Biol 1995 2.46
19 Dynamin is a GTPase stimulated to high levels of activity by microtubules. Nature 1992 2.45
20 The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. J Virol 2000 2.43
21 Interaction of brain cytoplasmic dynein and MAP2 with a common sequence at the C terminus of tubulin. Nature 1989 2.41
22 Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system. J Cell Biol 1984 2.38
23 The non-tubulin component of microtubule protein oligomers. Effect on self-association and hydrodynamic properties. J Biol Chem 1978 2.36
24 Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends. J Cell Sci 1999 2.32
25 Molecular cloning of the retrograde transport motor cytoplasmic dynein (MAP 1C). Neuron 1993 2.24
26 Identity and polymerization-stimulatory activity of the nontubulin proteins associated with microtubules. Biochemistry 1977 2.07
27 Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence. Neuroscience 1984 2.04
28 Widespread cellular distribution of MAP-1A (microtubule-associated protein 1A) in the mitotic spindle and on interphase microtubules. J Cell Biol 1984 2.03
29 Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2. J Biol Chem 1982 2.01
30 A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2). J Cell Biol 1981 1.97
31 Association of microtubule-associated protein 2 (MAP 2) with microtubules and intermediate filaments in cultured brain cells. J Cell Biol 1983 1.93
32 Low molecular weight microtubule-associated proteins are light chains of microtubule-associated protein 1 (MAP 1). Proc Natl Acad Sci U S A 1983 1.90
33 Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain. Proc Natl Acad Sci U S A 1993 1.88
34 Preparation of microtubules from rat liver and testis: cytoplasmic dynein is a major microtubule associated protein. Cell Motil Cytoskeleton 1989 1.83
35 Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin. J Biol Chem 2000 1.82
36 Reversible assembly purification of microtubules without assembly-promoting agents and further purification of tubulin, microtubule-associated proteins, and MAP fragments. Methods Enzymol 1986 1.82
37 Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function. J Cell Biol 1992 1.81
38 Cytoplasmic dynein and dynactin are required for the transport of microtubules into the axon. J Cell Biol 1998 1.80
39 Cytoskeletal architecture and immunocytochemical localization of microtubule-associated proteins in regions of axons associated with rapid axonal transport: the beta,beta'-iminodipropionitrile-intoxicated axon as a model system. J Cell Biol 1985 1.78
40 Microtubule-associated protein 1B: identification of a major component of the neuronal cytoskeleton. Proc Natl Acad Sci U S A 1985 1.72
41 Distinct but overlapping sites within the cytoplasmic dynein heavy chain for dimerization and for intermediate chain and light intermediate chain binding. J Biol Chem 2000 1.69
42 Removal of the projections from cytoplasmic microtubules in vitro by digestion with trypsin. J Biol Chem 1977 1.65
43 The involvement of the intermediate chain of cytoplasmic dynein in binding the motor complex to membranous organelles of Xenopus oocytes. Mol Biol Cell 1997 1.56
44 Isolation of sea urchin egg microtubules with taxol and identification of mitotic spindle microtubule-associated proteins with monoclonal antibodies. Proc Natl Acad Sci U S A 1983 1.55
45 Characterization of the microtubule-activated ATPase of brain cytoplasmic dynein (MAP 1C). J Cell Biol 1988 1.51
46 MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS. J Neurosci 1989 1.48
47 A binding site for SH3 domains targets dynamin to coated pits. J Biol Chem 1996 1.42
48 Multiple distinct coiled-coils are involved in dynamin self-assembly. J Biol Chem 1999 1.41
49 Frozen tissue sections as an experimental system to reveal specific binding sites for the regulatory subunit of type II cAMP-dependent protein kinase in neurons. Proc Natl Acad Sci U S A 1982 1.40
50 Purification of microtubules and microtubule-associated proteins from sea urchin eggs and cultured mammalian cells using taxol, and use of exogenous taxol-stabilized brain microtubules for purifying microtubule-associated proteins. Methods Enzymol 1986 1.38
51 Role of the basic, proline-rich region of dynamin in Src homology 3 domain binding and endocytosis. J Biol Chem 1997 1.35
52 Differential expression and phosphorylation of the 74-kDa intermediate chains of cytoplasmic dynein in cultured neurons and glia. J Biol Chem 1996 1.32
53 Isolated flagellar outer arm dynein translocates brain microtubules in vitro. Nature 1988 1.32
54 Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments. J Cell Sci 1999 1.28
55 Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeleton. Curr Biol 2000 1.28
56 Fast transport and retrograde movement of huntingtin and HAP 1 in axons. Neuroreport 1997 1.20
57 Purification of brain microtubules and microtubule-associated protein 1 using taxol. Methods Enzymol 1986 1.16
58 MAP2 (microtubule-associated protein 2). Cell Muscle Motil 1984 1.16
59 Developmental stage- and tissue-specific expression of shibire, a Drosophila gene involved in endocytosis. J Cell Sci 1992 1.16
60 Purification of brain cytoplasmic dynein and characterization of its in vitro properties. Methods Enzymol 1991 1.15
61 Microtubule-associated proteins: subunits of the cytomatrix. J Cell Biol 1984 1.15
62 Microtubule-associated proteins 1A and LC2. Two proteins encoded in one messenger RNA. J Biol Chem 1992 1.13
63 Molecular analysis of a cytoplasmic dynein light intermediate chain reveals homology to a family of ATPases. J Cell Sci 1995 1.13
64 A monoclonal antibody that cross-reacts with phosphorylated epitopes on two microtubule-associated proteins and two neurofilament polypeptides. Proc Natl Acad Sci U S A 1986 1.13
65 Extensive cAMP-dependent and cAMP-independent phosphorylation of microtubule-associated protein 2. J Biol Chem 1983 1.13
66 The RII subunit of cAMP-dependent protein kinase binds to a common amino-terminal domain in microtubule-associated proteins 2A, 2B, and 2C. Neuron 1989 1.13
67 Multiple mouse chromosomal loci for dynein-based motility. Genomics 1996 1.13
68 MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain. Neuron 1991 1.12
69 Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton. J Biol Chem 2001 1.05
70 Localization of motor-related proteins and associated complexes to active, but not inactive, centromeres. Hum Mol Genet 1998 1.02
71 Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins. Mol Biol Cell 1994 1.01
72 In vitro motility from recombinant dynein heavy chain. Proc Natl Acad Sci U S A 1996 1.00
73 Identification of high molecular weight microtubule-associated proteins in anterior pituitary tissue and cells using taxol-dependent purification combined with microtubule-associated protein specific antibodies. Biochemistry 1985 0.93
74 An axonemal dynein at the Hybrid Sterility 6 locus: implications for t haplotype-specific male sterility and the evolution of species barriers. Mamm Genome 2000 0.93
75 Domain structure and antiparallel dimers of microtubule-associated protein 2 (MAP2). J Struct Biol 1992 0.92
76 The role of dynein in retrograde axonal transport. Trends Neurosci 1989 0.92
77 A microtubule-activated ATPase from sea urchin eggs, distinct from cytoplasmic dynein and kinesin. Proc Natl Acad Sci U S A 1986 0.90
78 Subcellular targeting of the retrograde motor cytoplasmic dynein. Biochem Soc Trans 1995 0.90
79 Microtubule and axoneme gliding assays for force production by microtubule motor proteins. Methods Cell Biol 1993 0.88
80 Temperature-dependent reversible assembly of taxol-treated microtubules. J Cell Biol 1987 0.86
81 Characterization of the sea-urchin egg microtubule-activated ATPase. J Cell Sci Suppl 1986 0.86
82 Cross-linking of intermediate filaments to microtubules by microtubule-associated protein 2. Ann N Y Acad Sci 1985 0.85
83 Cell biology. Dynamin in synaptic dynamics. Nature 1993 0.85
84 Use of a heat-stable microtubule-associated protein class-specific antibody to investigate the mechanism of microtubule binding. J Biol Chem 1991 0.84
85 Purification and characterization of dynamin. Methods Enzymol 1991 0.84
86 Use of multiple monoclonal antibodies to characterize the major microtubule-associated protein in sea urchin eggs. Cell Motil 1985 0.82
87 Differential structure and distribution of the high molecular weight brain microtubule-associated proteins, MAP-1 and MAP-2. Ann N Y Acad Sci 1986 0.81
88 On the use of heat stability as a criterion for the identification of microtubule associated proteins (MAPs). Biochem Biophys Res Commun 1985 0.80
89 Antibody exchange immunochemistry. J Biol Chem 1990 0.80
90 Isolation of mitotic microtubule-associated proteins from sea urchin eggs. Ann N Y Acad Sci 1986 0.77
91 The two-step reversible denaturation of lactate dehydrogenase at low pH. Biochemistry 1975 0.75
92 Microtubule-associated protein 1A (MAP 1A) is a ganglion cell marker in adult rat retina. Vis Neurosci 1989 0.75
93 Dynamin: a microtubule-associated GTP-binding protein. J Cell Sci Suppl 1991 0.75
94 Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature 1992 0.75