Published in Biochemistry on June 14, 1977
Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line. J Cell Biol (1982) 9.66
A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs). J Cell Biol (1982) 4.94
Intracellular localization of the high molecular weight microtubule accessory protein by indirect immunofluorescence. J Cell Biol (1978) 2.53
Structure and phosphorylation of microtubule-associated protein 2 (MAP 2). Proc Natl Acad Sci U S A (1980) 2.41
Genetic dissection of the central pair microtubules of the flagella of Chlamydomonas reinhardtii. J Cell Biol (1984) 2.12
Self-assembly of microtubules in extracts of cultured HeLa cells and the identification of HeLa microtubule-associated proteins. Proc Natl Acad Sci U S A (1979) 1.99
A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2). J Cell Biol (1981) 1.97
Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors. J Cell Biol (1997) 1.97
Association of microtubule-associated protein 2 (MAP 2) with microtubules and intermediate filaments in cultured brain cells. J Cell Biol (1983) 1.93
Low molecular weight microtubule-associated proteins are light chains of microtubule-associated protein 1 (MAP 1). Proc Natl Acad Sci U S A (1983) 1.90
Immunofluorescence localization of HeLa cell microtubule-associated proteins on microtubules in vitro and in vivo. J Cell Biol (1980) 1.87
Phosphorylation of microtubule-associated proteins by a Ca2+/calmodulin-dependent protein kinase. J Cell Biol (1984) 1.61
Erythrocyte ankyrin: immunoreactive analogues are associated with mitotic structures in cultured cells and with microtubules in brain. Proc Natl Acad Sci U S A (1981) 1.52
Identity and Origin of the ATPase activity associated with neuronal microtubules. I. The ATPase activity is associated with membrane vesicles. J Cell Biol (1983) 1.38
In vitro polymerization of microtubules from HeLa cells. J Cell Biol (1978) 1.34
Microtubule-associated proteins of HeLa cells: heat stability of the 200,000 mol wt HeLa MAPs and detection of the presence of MAP-2 in HeLa cell extracts and cycled microtubules. J Cell Biol (1982) 1.30
In vivo and in vitro effects of the mitochondrial uncoupler FCCP on microtubules. EMBO J (1982) 1.20
Microtubule-associated proteins: subunits of the cytomatrix. J Cell Biol (1984) 1.15
Specific association of an M-phase kinase with isolated mitotic spindles and identification of two of its substrates as MAP4 and MAP1B. Cell Regul (1991) 1.10
Strongylocentrotus purpuratus spindle tubulin. I. Characteristics of its polymerization and depolymerization in vitro. J Cell Biol (1982) 1.07
Analysis of the primary sequence and microtubule-binding region of the Drosophila 205K MAP. J Cell Biol (1990) 1.07
Purification and characterization of a 190-kD microtubule-associated protein from bovine adrenal cortex. J Cell Biol (1986) 1.00
Specific association of STOP protein with microtubules in vitro and with stable microtubules in mitotic spindles of cultured cells. EMBO J (1990) 0.97
MHP1, an essential gene in Saccharomyces cerevisiae required for microtubule function. J Cell Biol (1996) 0.92
Differential phosphorylation of MAP-2 stimulated by calcium-calmodulin and cyclic AMP. Mol Cell Biol (1984) 0.92
Microtubule-associated proteins and in vitro astrocyte differentiation. J Cell Biol (1985) 0.91
Competitive inhibition of colchicine binding to tubulin by microtubule-associated proteins. Proc Natl Acad Sci U S A (1979) 0.87
Binding of microtubule protein to DNA and chromatin: possibility of simultaneous linkage of microtubule to nucleic and assembly of the microtubule structure. Nucleic Acids Res (1981) 0.84
Cytoplasmic microtubule assembly-disassembly from endogenous tubulin in a Brij-lysed cell model. J Cell Biol (1983) 0.82
The colchicine-binding protein of mammalian brain and its relation to microtubules. Biochemistry (1968) 12.96
The mechanism of action of colchicine. Binding of colchincine-3H to cellular protein. J Cell Biol (1967) 9.66
Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia. J Cell Biol (1999) 8.24
Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J Cell Biol (1996) 7.65
The mechanism of action of colchicine. Colchicine binding to sea urchin eggs and the mitotic apparatus. J Cell Biol (1967) 6.85
Microtubules. Annu Rev Biochem (1973) 6.75
Analysis of the actin-myosin II system in fish epidermal keratocytes: mechanism of cell body translocation. J Cell Biol (1997) 6.67
G protein signaling events are activated at the leading edge of chemotactic cells. Cell (1998) 6.60
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J Cell Biol (1997) 6.57
Association of high-molecular-weight proteins with microtubules and their role in microtubule assembly in vitro. Proc Natl Acad Sci U S A (1975) 6.35
Nucleated assembly of microtubules in porcine brain extracts. Science (1972) 6.22
A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes. J Exp Med (1976) 6.11
Head-to-tail polymerization of microtubules in vitro. Electron microscope analysis of seeded assembly. J Cell Biol (1980) 5.64
A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nat Cell Biol (2000) 5.29
Purification of tubulin and associated high molecular weight proteins from porcine brain and characterization of microtubule assembly in vitro. Ann N Y Acad Sci (1975) 5.26
Retrograde transport by the microtubule-associated protein MAP 1C. Nature (1987) 5.06
Effects of mutant rat dynamin on endocytosis. J Cell Biol (1993) 5.05
A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs). J Cell Biol (1982) 4.94
Microtubules: evidence for 13 protofilaments. J Cell Biol (1973) 4.91
Structural polarity and directional growth of microtubules of Chlamydomonas flagella. J Mol Biol (1974) 4.80
Two-gene control of the expression of a murine Ia antigen. J Exp Med (1978) 4.79
MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties. J Cell Biol (1987) 4.78
Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis. Nature (1991) 4.69
Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued. J Cell Biol (1995) 4.66
Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends. J Cell Biol (1987) 4.52
The pericentriolar material in Chinese hamster ovary cells nucleates microtubule formation. J Cell Biol (1977) 4.41
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins. Nature (1990) 4.30
Functional coordination of microtubule-based and actin-based motility in melanophores. Curr Biol (1998) 4.03
Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules. Cell (1989) 3.97
Self-polarization and directional motility of cytoplasm. Curr Biol (1999) 3.93
Monoclonal antibody against an Ir gene product? J Exp Med (1980) 3.88
Kinetochore microtubule dynamics and the metaphase-anaphase transition. J Cell Biol (1995) 3.86
Microtubule assembly in vitro. Fed Proc (1974) 3.82
Myosin II filament assemblies in the active lamella of fibroblasts: their morphogenesis and role in the formation of actin filament bundles. J Cell Biol (1995) 3.55
Direct observation of microtubule dynamics in living cells. Nature (1988) 3.47
On the complexity of self. Nature (1991) 3.43
DYNEINS: molecular structure and cellular function. Annu Rev Cell Biol (1994) 3.26
Cytoplasmic filaments and tubules. Fed Proc (1968) 3.22
Centriole cycle in Chinese hamster ovary cells as determined by whole-mount electron microscopy. J Cell Biol (1981) 3.17
Kinetic analysis of microtubule self-assembly in vitro. J Mol Biol (1977) 3.15
Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature (1991) 2.99
Microtubule release from the centrosome. Proc Natl Acad Sci U S A (1997) 2.97
Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes. J Exp Med (1976) 2.94
An extended microtubule-binding structure within the dynein motor domain. Nature (1997) 2.93
Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin. J Biol Chem (1993) 2.91
Isolated flagellar apparatus of Chlamydomonas: characterization of forward swimming and alteration of waveform and reversal of motion by calcium ions in vitro. J Cell Sci (1978) 2.91
Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization. Curr Biol (2001) 2.89
Detection of a common polypeptide chain in I--A and I--E sub-region immunoprecipitates. Mol Immunol (1979) 2.86
Contrasuppression. A novel immunoregulatory activity. J Exp Med (1981) 2.84
Phosphoproteins are components of mitotic microtubule organizing centers. Proc Natl Acad Sci U S A (1984) 2.84
Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation. J Cell Biol (1997) 2.78
Polarity of microtubules nucleated by centrosomes and chromosomes of Chinese hamster ovary cells in vitro. J Cell Biol (1980) 2.75
Polymerization of tubulin in vivo: direct evidence for assembly onto microtubule ends and from centrosomes. J Cell Biol (1985) 2.72
Characterization of microtubule assembly in porcine brain extracts by viscometry. Biochemistry (1973) 2.68
On the mechanisms of cytokinesis in animal cells. J Theor Biol (1983) 2.63
Correlative light and electron microscopy of the cytoskeleton of cultured cells. Methods Enzymol (1998) 2.59
Mutations in the tail domain of DYNC1H1 cause dominant spinal muscular atrophy. Neurology (2012) 2.56
Microtubule dynamics in vivo: a test of mechanisms of turnover. J Cell Biol (1987) 2.56
Injection of anticentromere antibodies in interphase disrupts events required for chromosome movement at mitosis. J Cell Biol (1990) 2.46
DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast. J Cell Biol (1995) 2.46
Dynamin is a GTPase stimulated to high levels of activity by microtubules. Nature (1992) 2.45
Microtubule-nucleating activity of centrosomes in Chinese hamster ovary cells is independent of the centriole cycle but coupled to the mitotic cycle. J Cell Biol (1981) 2.43
The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. J Virol (2000) 2.43
Dendritic organization of actin comet tails. Curr Biol (2001) 2.43
Ionic and nucleotide requirements for microtubule polymerization in vitro. Biochemistry (1975) 2.43
Interaction of brain cytoplasmic dynein and MAP2 with a common sequence at the C terminus of tubulin. Nature (1989) 2.41
Role of tubulin-associated proteins in microtubule nucleation and elongation. J Mol Biol (1977) 2.38
Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system. J Cell Biol (1984) 2.38
The non-tubulin component of microtubule protein oligomers. Effect on self-association and hydrodynamic properties. J Biol Chem (1978) 2.36
Monoclonal antibodies specific for Ia glycoproteins raised by immunization with activated T cells: possible role of T cellbound Ia antigens as targets of immunoregulatory T cells. J Immunol (1984) 2.35
Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton. J Cell Biol (1996) 2.35
A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines. Eur J Immunol (1989) 2.33
Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor. Cell (1990) 2.33
Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends. J Cell Sci (1999) 2.32
Microtubule dynamics and chromosome motion visualized in living anaphase cells. J Cell Biol (1988) 2.31
Molecular cloning of the retrograde transport motor cytoplasmic dynein (MAP 1C). Neuron (1993) 2.24
Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation. J Immunol (1989) 2.24
The role of microtubules in the movement of pigment granules in teleost melanophores. J Cell Biol (1974) 2.21
Microtuble assembly: some possible regulatory mechanisms. J Supramol Struct (1974) 2.21
Genetic and functional analysis of the Ia antigens: their possible role in regulating the immune response. Transplant Rev (1976) 2.15
Differential turnover of tyrosinated and detyrosinated microtubules. Proc Natl Acad Sci U S A (1987) 2.15
Variable synthesis and expression of E alpha and Ae (E beta) Ia polypeptide chains in mice of different H-2 haplotypes. Immunogenetics (1981) 2.13
Non-sarcomeric mode of myosin II organization in the fibroblast lamellum. J Cell Biol (1993) 2.10
Mode of centriole duplication and distribution. J Cell Biol (1990) 2.07
Microtubule treadmilling in vivo. Science (1997) 2.05
Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence. Neuroscience (1984) 2.04
Widespread cellular distribution of MAP-1A (microtubule-associated protein 1A) in the mitotic spindle and on interphase microtubules. J Cell Biol (1984) 2.03
Polarity of microtubules of the mitotic spindle. J Mol Biol (1978) 2.02
Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2. J Biol Chem (1982) 2.01
Self-assembly of microtubules in extracts of cultured HeLa cells and the identification of HeLa microtubule-associated proteins. Proc Natl Acad Sci U S A (1979) 1.99
A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2). J Cell Biol (1981) 1.97
Association of microtubule-associated protein 2 (MAP 2) with microtubules and intermediate filaments in cultured brain cells. J Cell Biol (1983) 1.93
Improved procedures for electron microscopic visualization of the cytoskeleton of cultured cells. J Struct Biol (1996) 1.93
Low molecular weight microtubule-associated proteins are light chains of microtubule-associated protein 1 (MAP 1). Proc Natl Acad Sci U S A (1983) 1.90
Colcemid inhibition of cell growth and the characterization of a colcemid-binding activity in Saccharomyces cerevisiae. J Cell Biol (1972) 1.89
Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain. Proc Natl Acad Sci U S A (1993) 1.88