Published in Proc Natl Acad Sci U S A on April 06, 2011
Viral modulation of programmed necrosis. Curr Opin Virol (2013) 1.20
DNA sensing-independent inhibition of herpes simplex virus 1 replication by DAI/ZBP1. J Virol (2013) 0.89
Distinct Z-DNA binding mode of a PKR-like protein kinase containing a Z-DNA binding domain (PKZ). Nucleic Acids Res (2014) 0.80
Antimicrobial peptide protegrin-3 adopt an antiparallel dimer in the presence of DPC micelles: a high-resolution NMR study. J Biomol NMR (2015) 0.75
Solution structure of the free Zα domain of human DLM-1 (ZBP1/DAI), a Z-DNA binding domain. J Biomol NMR (2014) 0.75
ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death. J Exp Med (2017) 0.75
NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J Biomol NMR (1995) 93.94
The Amber biomolecular simulation programs. J Comput Chem (2005) 28.84
Protein backbone angle restraints from searching a database for chemical shift and sequence homology. J Biomol NMR (1999) 26.99
Toll-like receptors. Annu Rev Immunol (2001) 26.06
Torsion angle dynamics for NMR structure calculation with the new program DYANA. J Mol Biol (1997) 15.40
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature (2007) 13.56
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity (2006) 10.61
A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat Immunol (2005) 7.94
Dipolar couplings in macromolecular structure determination. Methods Enzymol (2001) 3.46
Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules. Proc Natl Acad Sci U S A (2008) 3.27
Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA. Nat Immunol (2004) 3.18
Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA. Science (1999) 2.54
Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases. Nature (2005) 2.44
A role for Z-DNA binding in vaccinia virus pathogenesis. Proc Natl Acad Sci U S A (2003) 2.07
C-H...pi-interactions in proteins. J Mol Biol (2001) 2.06
Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins. Nat Struct Biol (2001) 2.04
A poxvirus protein forms a complex with left-handed Z-DNA: crystal structure of a Yatapoxvirus Zalpha bound to DNA. Proc Natl Acad Sci U S A (2004) 1.39
A set of HNCO-based experiments for measurement of residual dipolar couplings in 15N, 13C, (2H)-labeled proteins. J Biomol NMR (2000) 1.21
The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA. Proc Natl Acad Sci U S A (1999) 1.14
Suppression of anti-TROSY lines in a sensitivity enhanced gradient selection TROSY scheme. J Biomol NMR (2005) 1.10
The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitro. Proc Natl Acad Sci U S A (2004) 1.09
The crystal structure of the Zbeta domain of the RNA-editing enzyme ADAR1 reveals distinct conserved surfaces among Z-domains. J Mol Biol (2005) 1.04
The crystal structure of the second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA reveals an unusual binding mode to Z-DNA. Proc Natl Acad Sci U S A (2008) 1.01
Biochemical characterization and preliminary X-ray crystallographic study of the domains of human ZBP1 bound to left-handed Z-DNA. Biochim Biophys Acta (2006) 0.98
NMR spectroscopic elucidation of the B-Z transition of a DNA double helix induced by the Z alpha domain of human ADAR1. J Am Chem Soc (2009) 0.95
Characterization of DNA-binding activity of Z alpha domains from poxviruses and the importance of the beta-wing regions in converting B-DNA to Z-DNA. Nucleic Acids Res (2007) 0.89
Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome. PLoS Biol (2004) 6.67
Ubiquitin-binding domains. Biochem J (2006) 5.32
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125. EMBO J (2004) 2.53
Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases. Nature (2005) 2.44
Dynamic and clustering model of bacterial chemotaxis receptors: structural basis for signaling and high sensitivity. Proc Natl Acad Sci U S A (2002) 2.40
Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell (2007) 2.21
A-to-I RNA editing: recent news and residual mysteries. J Biol Chem (2002) 2.20
A role for Z-DNA binding in vaccinia virus pathogenesis. Proc Natl Acad Sci U S A (2003) 2.07
Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution. Proc Natl Acad Sci U S A (2002) 1.82
Crystal structure of ClpX molecular chaperone from Helicobacter pylori. J Biol Chem (2003) 1.72
Structure and function of HtrA family proteins, the key players in protein quality control. J Biochem Mol Biol (2005) 1.60
Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins. Prog Nucl Magn Reson Spectrosc (2009) 1.57
Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules. Nature (2003) 1.51
Structural and functional organization of the ESCRT-I trafficking complex. Cell (2006) 1.51
Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1. Cancer Res (2006) 1.50
Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Proc Natl Acad Sci U S A (2007) 1.50
EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex. Mol Cell (2012) 1.48
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 1984. 81: 7907-7911. J Immunol (2007) 1.45
Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog of mammalian adiponectin receptor. Mol Cell (2005) 1.42
A PKR-like eukaryotic initiation factor 2alpha kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains. Proc Natl Acad Sci U S A (2005) 1.40
A poxvirus protein forms a complex with left-handed Z-DNA: crystal structure of a Yatapoxvirus Zalpha bound to DNA. Proc Natl Acad Sci U S A (2004) 1.39
Proto-oncogene FBI-1 (Pokemon) and SREBP-1 synergistically activate transcription of fatty-acid synthase gene (FASN). J Biol Chem (2008) 1.32
Solution structure of a luteoviral P1-P2 frameshifting mRNA pseudoknot. J Mol Biol (2002) 1.31
Structure of an atypical orphan response regulator protein supports a new phosphorylation-independent regulatory mechanism. J Biol Chem (2007) 1.30
Evidence that vaccinia virulence factor E3L binds to Z-DNA in vivo: Implications for development of a therapy for poxvirus infection. Proc Natl Acad Sci U S A (2004) 1.30
Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism. J Biol Chem (2011) 1.30
Z-DNA-binding proteins can act as potent effectors of gene expression in vivo. Proc Natl Acad Sci U S A (2002) 1.26
Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane. FASEB J (2011) 1.25
Biological function of the vaccinia virus Z-DNA-binding protein E3L: gene transactivation and antiapoptotic activity in HeLa cells. Proc Natl Acad Sci U S A (2005) 1.25
A left-handed RNA double helix bound by the Z alpha domain of the RNA-editing enzyme ADAR1. Structure (2007) 1.22
Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866. J Mol Biol (2006) 1.19
Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, gamma-ear-containing, ADP-ribosylation-factor-binding proteins. Proc Natl Acad Sci U S A (2005) 1.16
Lactobacillus casei suppresses experimental arthritis by down-regulating T helper 1 effector functions. Mol Immunol (2008) 1.15
Crystal structure of the protease domain of a heat-shock protein HtrA from Thermotoga maritima. J Biol Chem (2002) 1.13
Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway. FASEB J (2002) 1.11
Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering. Proc Natl Acad Sci U S A (2012) 1.11
Characterization of Z-DNA as a nucleosome-boundary element in yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2007) 1.11
Crystal structure of RseB and a model of its binding mode to RseA. Proc Natl Acad Sci U S A (2007) 1.10
Angiotensin II-induced mitochondrial Nox4 is a major endogenous source of oxidative stress in kidney tubular cells. PLoS One (2012) 1.09
The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitro. Proc Natl Acad Sci U S A (2004) 1.09
Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis. Proc Natl Acad Sci U S A (2010) 1.08
FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease. J Clin Invest (2013) 1.08
Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK. J Biol Chem (2005) 1.07
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses. Nat Struct Mol Biol (2010) 1.06
Haplotype analysis of killer cell immunoglobulin-like receptor genes in 77 Korean families. Hum Immunol (2005) 1.05
Intrinsic Z-DNA is stabilized by the conformational selection mechanism of Z-DNA-binding proteins. J Am Chem Soc (2011) 1.04
The crystal structure of the Zbeta domain of the RNA-editing enzyme ADAR1 reveals distinct conserved surfaces among Z-domains. J Mol Biol (2005) 1.04
Association of HLA-DR and HLA-DQ genes with susceptibility to pulmonary tuberculosis in Koreans: preliminary evidence of associations with drug resistance, disease severity, and disease recurrence. Hum Immunol (2005) 1.03
Integrative package for low back pain with leg pain in Korea: a prospective cohort study. Complement Ther Med (2010) 1.03
Structure of human PRL-3, the phosphatase associated with cancer metastasis. FEBS Lett (2004) 1.02
Water-nucleobase "stacking": H-pi and lone pair-pi interactions in the atomic resolution crystal structure of an RNA pseudoknot. J Am Chem Soc (2003) 1.02
Crystal structure of osmotin, a plant antifungal protein. Proteins (2004) 1.01
The structural basis for the activation and peptide recognition of bacterial ClpP. J Mol Biol (2008) 1.01
The crystal structure of the second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA reveals an unusual binding mode to Z-DNA. Proc Natl Acad Sci U S A (2008) 1.01
Crystal structure of a luteoviral RNA pseudoknot and model for a minimal ribosomal frameshifting motif. Biochemistry (2005) 1.01
Quantitative evaluation of cardiomyocyte contractility in a 3D microenvironment. J Biomech (2008) 1.01
Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis. Proc Natl Acad Sci U S A (2010) 1.00
Effect of GCSB-5, a Herbal Formulation, on Monosodium Iodoacetate-Induced Osteoarthritis in Rats. Evid Based Complement Alternat Med (2012) 0.99
Biochemical characterization and preliminary X-ray crystallographic study of the domains of human ZBP1 bound to left-handed Z-DNA. Biochim Biophys Acta (2006) 0.98
Portable document format file showing the surface models of cadaver whole body. J Korean Med Sci (2012) 0.98
Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells. J Cell Sci (2012) 0.96
Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein. Nat Struct Mol Biol (2011) 0.96
Modulation of ADAR1 editing activity by Z-RNA in vitro. Nucleic Acids Res (2005) 0.95
Visible light crosslinkable chitosan hydrogels for tissue engineering. Acta Biomater (2012) 0.95
A Case of a Pulmonary Arteriovenous Malformation With Ebstein's Anomaly. Korean Circ J (2010) 0.95
NMR spectroscopic elucidation of the B-Z transition of a DNA double helix induced by the Z alpha domain of human ADAR1. J Am Chem Soc (2009) 0.95
Effects of bone morphogenetic protein-7 (BMP-7) on primordial follicular growth in the mouse ovary. Mol Reprod Dev (2004) 0.95
Protective effect of GCSB-5, an herbal preparation, against peripheral nerve injury in rats. J Ethnopharmacol (2011) 0.94
Association of HLA-DR and -DQ genes with narcolepsy in Koreans: comparison with two control groups, randomly selected subjects and DRB1*1501-DQB1*0602--positive subjects. Hum Immunol (2006) 0.94
Structural snapshots of heparin depolymerization by heparin lyase I. J Biol Chem (2009) 0.92
Therapeutic effect of Korean red ginseng on inflammatory cytokines in rats with focal cerebral ischemia/reperfusion injury. Am J Chin Med (2011) 0.92
The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ alpha(ADAR1). Nucleic Acids Res (2008) 0.92
Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity. J Biol Chem (2010) 0.92
The crystal structure Escherichia coli Spy. Protein Sci (2010) 0.92
Expression, purification and biochemical characterization of the N-terminal regions of human TIG3 and HRASLS3 proteins. Protein Expr Purif (2010) 0.92
The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination. J Biol Chem (2010) 0.91
The mechanism of temperature-induced bacterial HtrA activation. J Mol Biol (2008) 0.91
Adipose-derived stem cells and BMP-2 delivery in chitosan-based 3D constructs to enhance bone regeneration in a rat mandibular defect model. Tissue Eng Part A (2014) 0.91
Amplification of the gamma-irradiation-induced cell death pathway by reactive oxygen species in human U937 cells. Cell Signal (2008) 0.91
Intracellular localization of human ZBP1: Differential regulation by the Z-DNA binding domain, Zalpha, in splice variants. Biochem Biophys Res Commun (2006) 0.90
Enhanced osteogenesis of adipose derived stem cells with Noggin suppression and delivery of BMP-2. PLoS One (2013) 0.90