Published in Lancet Neurol on May 01, 2011
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The potassium channel KCa3.1 constitutes a pharmacological target for neuroinflammation associated with ischemia/reperfusion stroke. J Cereb Blood Flow Metab (2015) 0.78
A novel SPECT-based approach reveals early mechanisms of central and peripheral inflammation after cerebral ischemia. J Cereb Blood Flow Metab (2015) 0.77
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Lithium-induced neuroprotection in stroke involves increased miR-124 expression, reduced RE1-silencing transcription factor abundance and decreased protein deubiquitination by GSK3β inhibition-independent pathways. J Cereb Blood Flow Metab (2016) 0.76
Adenosine A2A receptors modulate acute injury and neuroinflammation in brain ischemia. Mediators Inflamm (2014) 0.76
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Tissue plasminogen activator followed by antioxidant-loaded nanoparticle delivery promotes activation/mobilization of progenitor cells in infarcted rat brain. Biomaterials (2015) 0.75
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Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med (2003) 3.89
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Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow. Circ Res (2006) 2.21
Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke. Stroke (2007) 2.10
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Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent. Stroke (2002) 2.00
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Hypoxia-induced stroke tolerance in the mouse is mediated by erythropoietin. Stroke (2003) 1.65
Estrogen increases bone marrow-derived endothelial progenitor cell production and diminishes neointima formation. Circulation (2003) 1.61
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Angiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury. FASEB J (2005) 1.54
Thrombotic stroke in the anesthetized monkey (Macaca mulatta): characterization by MRI--a pilot study. Cerebrovasc Dis (2012) 1.52
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Crosstalk between Rap1 and Rac regulates secretion of sAPPalpha. Nat Cell Biol (2003) 1.46
Mouse model of in situ thromboembolic stroke and reperfusion. Stroke (2007) 1.45
NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production. J Neurosci (2005) 1.44
Desferrioxamine induces delayed tolerance against cerebral ischemia in vivo and in vitro. J Cereb Blood Flow Metab (2002) 1.44
Cellular immunodepression preceding infectious complications after acute ischemic stroke in humans. Cerebrovasc Dis (2007) 1.42
Roller culture of free-floating retinal slices: a new system of organotypic cultures of adult rat retina. Ophthalmic Res (2006) 1.42
Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning. Glia (2005) 1.40
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Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury. J Immunol (2005) 1.39
Stroke propagates bacterial aspiration to pneumonia in a model of cerebral ischemia. Stroke (2006) 1.39
Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice. Brain Res (2002) 1.36
Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism. J Cereb Blood Flow Metab (2010) 1.35
Modeling stroke in mice - middle cerebral artery occlusion with the filament model. J Vis Exp (2011) 1.33
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SUMO2/3 conjugation is an endogenous neuroprotective mechanism. J Cereb Blood Flow Metab (2011) 1.32
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Neuroprotection and stroke: time for a compromise. J Neurochem (2007) 1.23
Serial analysis of gene expression identifies metallothionein-II as major neuroprotective gene in mouse focal cerebral ischemia. J Neurosci (2002) 1.22
Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. J Clin Invest (2004) 1.22
Preventive antibacterial treatment improves the general medical and neurological outcome in a mouse model of stroke. Stroke (2003) 1.21
Triptans reduce the inflammatory response in bacterial meningitis. J Cereb Blood Flow Metab (2002) 1.20
Isoflurane induced prolonged protection against cerebral ischemia in mice: a redox sensitive mechanism? Neuroreport (2002) 1.20
Oxygen glucose deprivation switches the transport of tPA across the blood-brain barrier from an LRP-dependent to an increased LRP-independent process. Stroke (2005) 1.18
Anti-cetuximab IgE ELISA for identification of patients at a high risk of cetuximab-induced anaphylaxis. MAbs (2011) 1.17
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Transforming growth factor-beta 1 potentiates amyloid-beta generation in astrocytes and in transgenic mice. J Biol Chem (2003) 1.17
Neuroprotective effects of atorvastatin against glutamate-induced excitotoxicity in primary cortical neurones. J Neurochem (2005) 1.17
Pharmacological uncoupling of activation induced increases in CBF and CMRO2. J Cereb Blood Flow Metab (2009) 1.16
Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling. J Biol Chem (2004) 1.16
Long-term remissions of severe pemphigus after rituximab therapy are associated with prolonged failure of desmoglein B cell response. Sci Transl Med (2013) 1.15
In vivo near-infrared fluorescence imaging of matrix metalloproteinase activity after cerebral ischemia. J Cereb Blood Flow Metab (2009) 1.15
IL-1β stimulates COX-2 dependent PGE₂ synthesis and CGRP release in rat trigeminal ganglia cells. PLoS One (2011) 1.13
Withdrawal of statin treatment abrogates stroke protection in mice. Stroke (2003) 1.13
Phosphatidylinositol 3-Akt-kinase-dependent phosphorylation of p21(Waf1/Cip1) as a novel mechanism of neuroprotection by glucocorticoids. J Neurosci (2007) 1.12
Cerebrovascular vasodilation to extraluminal acidosis occurs via combined activation of ATP-sensitive and Ca2+-activated potassium channels. J Cereb Blood Flow Metab (2003) 1.12
Activation of microglial N-methyl-D-aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain. Ann Neurol (2012) 1.12
Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility. Brain (2011) 1.11
Functional neurological recovery after spinal cord injury is impaired in patients with infections. Brain (2012) 1.11
Transforming growth factor-beta and ischemic brain injury. Cell Mol Neurobiol (2003) 1.10
Essential role of interleukin-6 in post-stroke angiogenesis. Brain (2012) 1.09
Quantification and clinical relevance of brain atrophy in multiple sclerosis: a review. J Neurol (2009) 1.08
Cancer risk and impact of disease-modifying treatments in patients with multiple sclerosis. Mult Scler (2008) 1.08
Immune responses after acute ischemic stroke or myocardial infarction. Int J Cardiol (2010) 1.08
Neuronal gelsolin prevents apoptosis by enhancing actin depolymerization. Mol Cell Neurosci (2004) 1.07
Transforming growth factor-beta signalling in brain disorders. Cytokine Growth Factor Rev (2005) 1.07
Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state. Proc Natl Acad Sci U S A (2012) 1.07
Protective conditioning of the brain: expressway or roadblock? J Physiol (2011) 1.05
Equivocal roles of tissue-type plasminogen activator in stroke-induced injury. Trends Neurosci (2004) 1.05
Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance. J Immunol (2010) 1.05
Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription. Biochem J (2004) 1.04
Tissue plasminogen activator prevents white matter damage following stroke. J Exp Med (2011) 1.03
Effects of the PDE5-inhibitor vardenafil in a mouse stroke model. Brain Res (2009) 1.03
Neurobehavioral and immunological consequences of prenatal immune activation in rats. Influence of antipsychotics. Neuropsychopharmacology (2006) 1.02
Near-infrared fluorescence imaging with fluorescently labeled albumin: a novel method for non-invasive optical imaging of blood-brain barrier impairment after focal cerebral ischemia in mice. J Neurosci Methods (2009) 1.01
Circulating monocytic cells infiltrate layers of anterograde axonal degeneration where they transform into microglia. FASEB J (2005) 1.01