Published in Cell on April 20, 1990
An analysis of vertebrate mRNA sequences: intimations of translational control. J Cell Biol (1991) 12.00
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev (1998) 8.51
Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci U S A (1990) 7.39
Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Natl Acad Sci U S A (1997) 5.44
Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response. EMBO J (1994) 4.03
Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family. Proc Natl Acad Sci U S A (1991) 3.31
Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med (1994) 3.11
The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Mol Cell Biol (1991) 2.77
Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130. EMBO J (1991) 2.56
Efficient screening of retroviral cDNA expression libraries. Proc Natl Acad Sci U S A (1995) 2.46
Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily. Proc Natl Acad Sci U S A (1992) 2.17
Three different mRNAs encoding human granulocyte colony-stimulating factor receptor. Proc Natl Acad Sci U S A (1990) 1.97
Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis. Cytokine (2008) 1.95
Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3). EMBO J (1992) 1.86
Molecular cloning and expression of the murine interleukin-5 receptor. EMBO J (1990) 1.85
PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors. EMBO J (1998) 1.84
Functional domains of the granulocyte colony-stimulating factor receptor. EMBO J (1991) 1.82
Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains. J Exp Med (1990) 1.63
Expression of the Evi-1 zinc finger gene in 32Dc13 myeloid cells blocks granulocytic differentiation in response to granulocyte colony-stimulating factor. Mol Cell Biol (1992) 1.61
TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis. EMBO J (1998) 1.60
Molecular cloning and expression of a cDNA encoding the secretin receptor. EMBO J (1991) 1.60
Interleukin-6: structure-function relationships. Protein Sci (1997) 1.59
Comparison of long and short forms of the prolactin receptor on prolactin-induced milk protein gene transcription. Proc Natl Acad Sci U S A (1991) 1.40
Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation. Mol Cell Biol (1993) 1.38
Organization of the murine and human interleukin-7 receptor genes: two mRNAs generated by differential splicing and presence of a type I-interferon-inducible promoter. Mol Cell Biol (1991) 1.37
Molecular cloning and expression of the human interleukin 5 receptor. J Exp Med (1992) 1.31
Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation. Proc Natl Acad Sci U S A (1994) 1.29
The integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transduction. EMBO J (1991) 1.26
Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal. EMBO J (1993) 1.26
Homodimeric cross-over structure of the human granulocyte colony-stimulating factor (GCSF) receptor signaling complex. Proc Natl Acad Sci U S A (2006) 1.26
High-efficiency identification of genes by functional analysis from a retroviral cDNA expression library. J Virol (1994) 1.21
Distinct regions of the human granulocyte-colony-stimulating factor receptor cytoplasmic domain are required for proliferation and gene induction. Mol Cell Biol (1993) 1.20
Characterization of a binding protein for leukemia inhibitory factor localized in extracellular matrix. J Cell Biol (1993) 1.20
Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha. Nucleic Acids Res (1998) 1.17
A major binding protein for leukemia inhibitory factor in normal mouse serum: identification as a soluble form of the cellular receptor. Proc Natl Acad Sci U S A (1992) 1.10
Signal transduction mediated by growth hormone receptor and its chimeric molecules with the granulocyte colony-stimulating factor receptor. Proc Natl Acad Sci U S A (1993) 1.09
Tyrosine 763 of the murine granulocyte colony-stimulating factor receptor mediates Ras-dependent activation of the JNK/SAPK mitogen-activated protein kinase pathway. Mol Cell Biol (1997) 1.05
Identification of the ligand-binding regions in the macrophage colony-stimulating factor receptor extracellular domain. Mol Cell Biol (1993) 1.03
Myeloid-specific transcriptional activation by murine myeloid zinc-finger protein 2. Proc Natl Acad Sci U S A (1998) 1.03
Mechanisms of neutropenia involving myeloid maturation arrest in burn sepsis. Ann Surg (1998) 1.01
Characterization of the receptor binding determinants of granulocyte colony stimulating factor. Protein Sci (1997) 0.96
Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment. J Exp Med (1999) 0.95
Premature expression of the macrophage colony-stimulating factor receptor on a multipotential stem cell line does not alter differentiation lineages controlled by stromal cells used for coculture. J Exp Med (1991) 0.91
Myeloblastin is a granulocyte colony-stimulating factor-responsive gene conferring factor-independent growth to hematopoietic cells. Proc Natl Acad Sci U S A (2000) 0.91
Distinct downstream signaling mechanism between erythropoietin receptor and interleukin-2 receptor. EMBO J (1992) 0.90
Characterization of mpl cytoplasmic domain sequences required for myeloproliferative leukemia virus pathogenicity. J Virol (1994) 0.89
Cytokine receptors: structure and signal transduction. Clin Exp Immunol (1992) 0.89
Unregulated expression of the erythropoietin receptor gene caused by insertion of spleen focus-forming virus long terminal repeat in a murine erythroleukemia cell line. Mol Cell Biol (1991) 0.88
Distinct signal transduction through the tyrosine-containing domains of the granulocyte colony-stimulating factor receptor. EMBO J (1995) 0.85
Inter-species chimeras of leukaemia inhibitory factor define a major human receptor-binding determinant. EMBO J (1993) 0.83
Induction of junB expression, but not c-jun, by granulocyte colony-stimulating factor or macrophage colony-stimulating factor in the proliferative response of human myeloid leukemia cells. J Clin Invest (1992) 0.83
Apoptosis of hemopoietic cells by the human granulocyte-macrophage colony-stimulating factor mutant E21R. Proc Natl Acad Sci U S A (1996) 0.82
Granulocyte colony-stimulating factor receptor mutations in myeloid malignancy. Front Oncol (2014) 0.82
Stimulation of coronary collateral growth by granulocyte stimulating factor: role of reactive oxygen species. Arterioscler Thromb Vasc Biol (2009) 0.80
Alternatively spliced forms in the cytoplasmic domain of the human growth hormone (GH) receptor regulate its ability to generate a soluble GH-binding protein. Proc Natl Acad Sci U S A (1996) 0.78
Granulocyte colony-stimulating factor and leukemogenesis. Mediators Inflamm (2004) 0.78
Regulation of the differentiation of WEHI-3B D+ leukemia cells by granulocyte colony-stimulating factor receptor. J Cell Biol (1993) 0.77
Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition. Leukemia (2013) 0.77
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature (1992) 12.92
pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res (1990) 12.75
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell (1991) 10.96
Lethal effect of the anti-Fas antibody in mice. Nature (1993) 9.20
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell (1993) 9.06
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature (1998) 8.93
Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor. Nature (1986) 7.73
Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science (1994) 7.34
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell (1994) 7.23
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature (1998) 6.47
Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1 alpha. J Biol Chem (1989) 5.09
Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature (1996) 4.92
The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha. Nature (1980) 4.82
Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature (1995) 4.20
Downregulation of Fas ligand by shedding. Nat Med (1998) 3.83
A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. J Biol Chem (1993) 3.81
Synthesis in E. coli of a polypeptide with human leukocyte interferon activity. Nature (1980) 3.78
The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J Immunol (1992) 3.66
Chromospheric alfvenic waves strong enough to power the solar wind. Science (2007) 3.58
Human leukocyte and fibroblast interferons are structurally related. Nature (1980) 3.57
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44
Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med (1994) 3.11
Sequence diversity of small, round-structured viruses in the Norwalk virus group. J Virol (1994) 3.11
Essential roles of the Fas ligand in the development of hepatitis. Nat Med (1997) 3.05
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ (2005) 2.91
Expression of the functional soluble form of human fas ligand in activated lymphocytes. EMBO J (1995) 2.87
Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain. Proc Natl Acad Sci U S A (1986) 2.83
Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc Natl Acad Sci U S A (1993) 2.81
Laparoscopic and endoscopic cooperative surgery for gastrointestinal stromal tumor dissection. Surg Endosc (2007) 2.77
Polypeptide chain elongation factor 1 alpha (EF-1 alpha) from yeast: nucleotide sequence of one of the two genes for EF-1 alpha from Saccharomyces cerevisiae. EMBO J (1984) 2.77
Human Fas ligand: gene structure, chromosomal location and species specificity. Int Immunol (1994) 2.74
Correlation of patient immune responses with genetically characterized small round-structured viruses involved in outbreaks of nonbacterial acute gastroenteritis in the United States, 1990 to 1995. J Med Virol (1997) 2.70
Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver. Nat Genet (1995) 2.65
Construction of a dictionary of sequence motifs that characterize groups of related proteins. Protein Eng (1992) 2.58
Expression of the Fas ligand in cells of T cell lineage. J Immunol (1995) 2.54
Fas ligand in human serum. Nat Med (1996) 2.53
Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis. Science (1997) 2.52
The nucleotide sequence of a cloned human leukocyte interferon cDNA. Gene (1980) 2.51
Effect of bcl-2 on Fas antigen-mediated cell death. J Immunol (1993) 2.50
Caspase 1-independent IL-1beta release and inflammation induced by the apoptosis inducer Fas ligand. Nat Med (1998) 2.47
Rational design of potent antagonists to the human growth hormone receptor. Science (1992) 2.45
Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis. J Clin Invest (1999) 2.43
At least three human type alpha interferons: structure of alpha 2. Science (1980) 2.38
Chromosomal gene structure of human myeloperoxidase and regulation of its expression by granulocyte colony-stimulating factor. J Biol Chem (1987) 2.36
Molecular cloning and sequence determination of the nuclear gene coding for mitochondrial elongation factor Tu of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1983) 2.33
Two species of human CRK cDNA encode proteins with distinct biological activities. Mol Cell Biol (1992) 2.30
LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response. J Immunol (2000) 2.27
Application of PCR to detect Norwalk virus in fecal specimens from outbreaks of gastroenteritis. J Clin Microbiol (1994) 2.27
Total en bloc spondylectomy for solitary spinal metastases. Int Orthop (1994) 2.22
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway. Nat Med (2000) 2.18
Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver. Science (2001) 2.17
mRNA capping enzyme. Isolation and characterization of the gene encoding mRNA guanylytransferase subunit from Saccharomyces cerevisiae. J Biol Chem (1992) 2.12
The chromosomal gene structure and two mRNAs for human granulocyte colony-stimulating factor. EMBO J (1986) 1.98
Three different mRNAs encoding human granulocyte colony-stimulating factor receptor. Proc Natl Acad Sci U S A (1990) 1.97
Isolation and characterization of the cDNA for murine granulocyte colony-stimulating factor. Proc Natl Acad Sci U S A (1986) 1.94
Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3). J Biol Chem (1999) 1.93
Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide. Neuron (1992) 1.90
Target cell specificity of two species of human interferon-alpha produced in Escherichia coli and of hybrid molecules derived from them. Proc Natl Acad Sci U S A (1981) 1.89
High Fas ligand expression on lymphocytes in lesions of ulcerative colitis. Gut (1998) 1.88
Caspase-independent cell killing by Fas-associated protein with death domain. J Cell Biol (1998) 1.87
Functional domains of the granulocyte colony-stimulating factor receptor. EMBO J (1991) 1.82
Localization of Evi-2 to chromosome 11: linkage to other proto-oncogene and growth factor loci using interspecific backcross mice. Oncogene Res (1988) 1.82
Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med (1997) 1.80
Spontaneous rupture: a complication of benign mature teratomas of the mediastinum. AJR Am J Roentgenol (1998) 1.73
Necrotic death pathway in Fas receptor signaling. J Cell Biol (2000) 1.68
Detection of microcystins, a blue-green algal hepatotoxin, in drinking water sampled in Haimen and Fusui, endemic areas of primary liver cancer in China, by highly sensitive immunoassay. Carcinogenesis (1996) 1.65
Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha-induced cell death in fibroblasts. Proc Natl Acad Sci U S A (2000) 1.65
A comprehensive genetic map of murine chromosome 11 reveals extensive linkage conservation between mouse and human. Genetics (1989) 1.65
TCR/CD3 coupling to Fas-based cytotoxicity. J Exp Med (1995) 1.64
Characterization of a gene responsible for the Na+/H+ antiporter system of alkalophilic Bacillus species strain C-125. Mol Microbiol (1994) 1.63
Purification and characterization of the receptor for murine granulocyte colony-stimulating factor. J Biol Chem (1990) 1.60
Molecular cloning and expression of a cDNA encoding the secretin receptor. EMBO J (1991) 1.60
The estimated incidence of cystic fibrosis in Japan. J Pediatr Gastroenterol Nutr (1997) 1.58
Smoke-like echo in the left atrial cavity in mitral valve disease: its features and significance. J Am Coll Cardiol (1985) 1.58
Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody. J Exp Med (1995) 1.57
Homology between mammalian DNA polymerase beta and terminal deoxynucleotidyltransferase. J Biol Chem (1987) 1.57
Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death. J Exp Med (1996) 1.56
The chromosomal gene structure for murine granulocyte colony-stimulating factor. Eur J Biochem (1987) 1.55
Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells. J Exp Med (1997) 1.52
Relationships between perceived workload, stress and oxidative DNA damage. Int Arch Occup Environ Health (2001) 1.51
Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor. Cell (1993) 1.51
Dialysis patients' preferences regarding cardiopulmonary resuscitation and withdrawal of dialysis in Japan. Am J Kidney Dis (2001) 1.51
Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice. J Exp Med (1997) 1.51
Improvement in pulmonary function in mitral stenosis after percutaneous transvenous mitral commissurotomy. Chest (1990) 1.48
Application of Doppler color flow imaging to determine valve area in mitral stenosis. J Am Coll Cardiol (1991) 1.47
Growth of Japanese breastfed infants compared to national references and World Health Organization growth standards. Acta Paediatr (2013) 1.47
A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection. J Exp Med (1996) 1.46
Molecular analysis of the human interferon-alpha gene family. Gene (1981) 1.44
Determination of Aconitum alkaloids in blood and urine samples. II. Capillary liquid chromatographic-frit fast atom bombardment mass spectrometric analysis. J Chromatogr B Biomed Sci Appl (1998) 1.43
Fas-mediated apoptosis in primary cultured mouse hepatocytes. Exp Cell Res (1994) 1.41