Published in Int J Biol Macromol on May 23, 2011
Important determinants for fucoidan bioactivity: a critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds. Mar Drugs (2011) 1.25
Fucoidan as a marine anticancer agent in preclinical development. Mar Drugs (2014) 1.14
Fucoidan and cancer: a multifunctional molecule with anti-tumor potential. Mar Drugs (2015) 1.07
Marine polysaccharides from algae with potential biomedical applications. Mar Drugs (2015) 1.04
Effects of oral administration of fucoidan extracted from Cladosiphon okamuranus on tumor growth and survival time in a tumor-bearing mouse model. Mar Drugs (2012) 0.99
Fucose-containing sulfated polysaccharides from brown seaweeds inhibit proliferation of melanoma cells and induce apoptosis by activation of caspase-3 in vitro. Mar Drugs (2011) 0.89
Prophylactic administration of fucoidan represses cancer metastasis by inhibiting vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) in Lewis tumor-bearing mice. Mar Drugs (2015) 0.87
Purification of a low molecular weight fucoidan for SPECT molecular imaging of myocardial infarction. Mar Drugs (2014) 0.85
Anticancer and cancer preventive properties of marine polysaccharides: some results and prospects. Mar Drugs (2013) 0.82
Looking Beyond the Terrestrial: The Potential of Seaweed Derived Bioactives to Treat Non-Communicable Diseases. Mar Drugs (2016) 0.82
Fucoidan inhibits the growth of hepatocellular carcinoma independent of angiogenesis. Evid Based Complement Alternat Med (2013) 0.81
Evaluation of adjuvant effects of fucoidan for improving vaccine efficacy. J Vet Sci (2014) 0.79
PDZ-binding kinase/T-LAK cell-originated protein kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth. Oncotarget (2016) 0.78
Fucoidan enhances the therapeutic potential of arsenic trioxide and all-trans retinoic acid in acute promyelocytic leukemia, in vitro and in vivo. Oncotarget (2016) 0.78
ERK Activation by Fucoidan Leads to Inhibition of Melanogenesis in Mel-Ab Cells. Korean J Physiol Pharmacol (2014) 0.78
High cytotoxicity and anti-proliferative activity of algae extracts on an in vitro model of human hepatocellular carcinoma. Springerplus (2016) 0.77
Fucoidan promotes the reconstruction of skin equivalents. Korean J Physiol Pharmacol (2014) 0.77
Molecular Mechanisms by Which a Fucus vesiculosus Extract Mediates Cell Cycle Inhibition and Cell Death in Pancreatic Cancer Cells. Mar Drugs (2015) 0.76
Melanoma and brown seaweed: an integrative hypothesis. J Appl Phycol (2016) 0.75
Fucoidans Disrupt Adherence of Helicobacter pylori to AGS Cells In Vitro. Evid Based Complement Alternat Med (2015) 0.75
Anti-Cancerous Potential of Polysaccharide Fractions Extracted from Peony Seed Dreg on Various Human Cancer Cell Lines Via Cell Cycle Arrest and Apoptosis. Front Pharmacol (2017) 0.75
A New Route of Fucoidan Immobilization on Low Density Polyethylene and Its Blood Compatibility and Anticoagulation Activity. Int J Mol Sci (2016) 0.75
Fabrication and Cytotoxicity of Fucoidan-Cisplatin Nanoparticles for Macrophage and Tumor Cells. Materials (Basel) (2017) 0.75
Oligo-Fucoidan prevents IL-6 and CCL2 production and cooperates with p53 to suppress ATM signaling and tumor progression. Sci Rep (2017) 0.75
Fucoidan Does Not Exert Anti-Tumorigenic Effects on Uveal Melanoma Cell Lines. Mar Drugs (2017) 0.75
Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets. Trends Cell Biol (2004) 3.18
The Hsp70 and TRiC/CCT chaperone systems cooperate in vivo to assemble the von Hippel-Lindau tumor suppressor complex. Mol Cell Biol (2003) 1.62
Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT. Nat Struct Mol Biol (2008) 1.51
Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein. J Biol Chem (2003) 1.49
Phytate: impact on environment and human nutrition. A challenge for molecular breeding. J Zhejiang Univ Sci B (2008) 1.49
Evaluation of minimal Trichoderma reesei cellulase mixtures on differently pretreated Barley straw substrates. Biotechnol Prog (2007) 1.43
Lignocellulose pretreatment severity - relating pH to biomatrix opening. N Biotechnol (2010) 1.35
Efficiency of new fungal cellulase systems in boosting enzymatic degradation of barley straw lignocellulose. Biotechnol Prog (2006) 1.29
The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression. J Exp Med (2003) 1.28
Important determinants for fucoidan bioactivity: a critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds. Mar Drugs (2011) 1.25
The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu). Planta Med (2006) 1.20
Novel cell wall architecture of isoxaben-habituated Arabidopsis suspension-cultured cells: global transcript profiling and cellular analysis. Plant J (2004) 1.19
Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins. J Agric Food Chem (2005) 1.17
Colorimetric characterization for comparative analysis of fungal pigments and natural food colorants. J Agric Food Chem (2006) 1.17
Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle. EMBO J (2011) 1.12
LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowth. PLoS One (2012) 1.10
Reactor design for minimizing product inhibition during enzymatic lignocellulose hydrolysis: I. Significance and mechanism of cellobiose and glucose inhibition on cellulolytic enzymes. Biotechnol Adv (2010) 1.09
Enzymatic hydrolysis of water-soluble wheat arabinoxylan. 1. Synergy between alpha-L-arabinofuranosidases, endo-1,4-beta-xylanases, and beta-xylosidase activities. Biotechnol Bioeng (2003) 1.08
Effects of substrate loading on enzymatic hydrolysis and viscosity of pretreated barley straw. Appl Biochem Biotechnol (2007) 1.08
Formation of Pmel17 amyloid is regulated by juxtamembrane metalloproteinase cleavage, and the resulting C-terminal fragment is a substrate for gamma-secretase. J Biol Chem (2008) 1.07
Amyloid precursor protein (APP) regulates synaptic structure and function. Mol Cell Neurosci (2012) 1.06
Apoptosis of intestinal crypt epithelium after Cryptosporidium parvum infection. J Infect Chemother (2003) 1.06
Quantitative analysis of phytate globoids isolated from wheat bran and characterization of their sequential dephosphorylation by wheat phytase. J Agric Food Chem (2007) 1.04
Exploring fungal biodiversity for the production of water-soluble pigments as potential natural food colorants. Curr Opin Biotechnol (2005) 1.03
IL-10 controls Th2-type cytokine production and eosinophil infiltration in a mouse model of allergic airway inflammation. Immunobiology (2010) 1.03
Fungal polyketide azaphilone pigments as future natural food colorants? Trends Biotechnol (2010) 1.02
Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida. In Vivo (2003) 1.01
A novel GH43 alpha-L-arabinofuranosidase from Humicola insolens: mode of action and synergy with GH51 alpha-L-arabinofuranosidases on wheat arabinoxylan. Appl Microbiol Biotechnol (2006) 1.00
The cotranslational contacts between ribosome-bound nascent polypeptides and the subunits of the hetero-oligomeric chaperonin TRiC probed by photocross-linking. J Biol Chem (2005) 1.00
Identification of potentially safe promising fungal cell factories for the production of polyketide natural food colorants using chemotaxonomic rationale. Microb Cell Fact (2009) 0.99
Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein. J Biol Chem (2011) 0.97
A gradient of ATP affinities generates an asymmetric power stroke driving the chaperonin TRIC/CCT folding cycle. Cell Rep (2012) 0.97
Enzymatic xylose release from pretreated corn bran arabinoxylan: differential effects of deacetylation and deferuloylation on insoluble and soluble substrate fractions. J Agric Food Chem (2010) 0.97
Identification of thermostable beta-xylosidase activities produced by Aspergillus brasiliensis and Aspergillus niger. Biotechnol Lett (2007) 0.97
Enzymatic lignocellulose hydrolysis: Improved cellulase productivity by insoluble solids recycling. Biotechnol Biofuels (2013) 0.96
Mode of action of pectin lyase A of Aspergillus niger on differently C(6)-substituted oligogalacturonides. J Biol Chem (2002) 0.95
Effect of xanthan on flavor release from thickened viscous food model systems. J Agric Food Chem (2005) 0.93
In vitro fermentation of arabinoxylan-derived carbohydrates by bifidobacteria and mixed fecal microbiota. J Agric Food Chem (2009) 0.93
Reactor design for minimizing product inhibition during enzymatic lignocellulose hydrolysis: II. Quantification of inhibition and suitability of membrane reactors. Biotechnol Adv (2010) 0.92
Enzymatic hydrolysis of wheat arabinoxylan by a recombinant "minimal" enzyme cocktail containing beta-xylosidase and novel endo-1,4-beta-xylanase and alpha-l-arabinofuranosidase activities. Biotechnol Prog (2007) 0.90
Effect of ripeness and postharvest storage on the phenolic profiles of Cherries (Prunus avium L.). J Agric Food Chem (2004) 0.90
Comparison of different pretreatment strategies for enzymatic hydrolysis of wheat and barley straw. Appl Biochem Biotechnol (2007) 0.89
Fucose-containing sulfated polysaccharides from brown seaweeds inhibit proliferation of melanoma cells and induce apoptosis by activation of caspase-3 in vitro. Mar Drugs (2011) 0.89
Definition and characterization of enzymes for maximal biocatalytic solubilization of prebiotic polysaccharides from potato pulp. Enzyme Microb Technol (2011) 0.88
Influence of substrate particle size and wet oxidation on physical surface structures and enzymatic hydrolysis of wheat straw. Biotechnol Prog (2009) 0.88
Computerized screening for novel producers of Monascus-like food pigments in Penicillium species. J Agric Food Chem (2008) 0.87
Suppression of Th2 immune responses by mekabu fucoidan from Undaria pinnatifida sporophylls. Int Arch Allergy Immunol (2005) 0.87
Expression and characterization of an endo-1,4-β-galactanase from Emericella nidulans in Pichia pastoris for enzymatic design of potentially prebiotic oligosaccharides from potato galactans. Enzyme Microb Technol (2011) 0.86
Maximal release of highly bifidogenic soluble dietary fibers from industrial potato pulp by minimal enzymatic treatment. Appl Microbiol Biotechnol (2011) 0.86
Modeling of possible subunit arrangements in the eukaryotic chaperonin TRiC. Protein Sci (2006) 0.86
Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β. FEBS J (2011) 0.85
Low temperature lignocellulose pretreatment: effects and interactions of pretreatment pH are critical for maximizing enzymatic monosaccharide yields from wheat straw. Biotechnol Biofuels (2011) 0.85
Chemical and olfactometric characterization of volatile flavor compounds in a fish oil enriched milk emulsion. J Agric Food Chem (2004) 0.85
Immune responses to Nippostrongylus brasiliensis and tuberculin protein in GATA-3-transgenic mice. Immunol Lett (2005) 0.84
Identification, expression, and characterization of a novel bacterial RGI lyase enzyme for the production of bio-functional fibers. Enzyme Microb Technol (2011) 0.84
In vitro fermentation of sugar beet arabino-oligosaccharides by fecal microbiota obtained from patients with ulcerative colitis to selectively stimulate the growth of Bifidobacterium spp. and Lactobacillus spp. Appl Environ Microbiol (2011) 0.84
Leucine-rich repeat kinase 2 regulates tau phosphorylation through direct activation of glycogen synthase kinase-3β. FEBS J (2013) 0.84
Evaluation of Epicoccum nigrum for growth, morphology and production of natural colorants in liquid media and on a solid rice medium. Biotechnol Lett (2008) 0.83
Effect and modeling of glucose inhibition and in situ glucose removal during enzymatic hydrolysis of pretreated wheat straw. Appl Biochem Biotechnol (2009) 0.83
Methods for improving enzymatic trans-glycosylation for synthesis of human milk oligosaccharide biomimetics. J Agric Food Chem (2014) 0.83
Involvement of GATA-3-dependent Th2 lymphocyte activation in airway hyperresponsiveness. Am J Physiol Lung Cell Mol Physiol (2006) 0.83
High-throughput screening of Erwinia chrysanthemi pectin methylesterase variants using carbohydrate microarrays. Proteomics (2009) 0.83
Suppression of collagen-induced arthritis by oral administration of the citrus flavonoid hesperidin. Planta Med (2006) 0.83
Th2 immune response plays a critical role in the development of nickel-induced allergic contact dermatitis. Int Arch Allergy Immunol (2010) 0.82
Oxidative stability of fish and algae oils containing long-chain polyunsaturated fatty acids in bulk and in oil-in-water emulsions. J Agric Food Chem (2002) 0.82
Natural killer T cells are required for lipopolysaccharide-mediated enhancement of atherosclerosis in apolipoprotein E-deficient mice. Immunobiology (2012) 0.82
Suppression of infection-induced endotoxin shock in mice by a citrus flavanone naringin. Planta Med (2004) 0.81
Feruloylated and nonferuloylated arabino-oligosaccharides from sugar beet pectin selectively stimulate the growth of Bifidobacterium spp. in human fecal in vitro fermentations. J Agric Food Chem (2011) 0.81
A citrus flavonoid hesperidin suppresses infection-induced endotoxin shock in mice. Biol Pharm Bull (2004) 0.81
Optimization of reaction conditions for enzymatic viscosity reduction and hydrolysis of wheat arabinoxylan in an industrial ethanol fermentation residue. Biotechnol Prog (2006) 0.81
Suppression of inflammatory responses after onset of collagen-induced arthritis in mice by oral administration of the Citrus flavanone naringin. Immunopharmacol Immunotoxicol (2011) 0.81
Modeling the sensory impact of defined combinations of volatile lipid oxidation products on fishy and metallic off-flavors. J Agric Food Chem (2004) 0.80
Identification of a laccase from Ganoderma lucidum CBS 229.93 having potential for enhancing cellulase catalyzed lignocellulose degradation. Enzyme Microb Technol (2013) 0.80
pH catalyzed pretreatment of corn bran for enhanced enzymatic arabinoxylan degradation. N Biotechnol (2010) 0.80
Ascorbyl palmitate, gamma-tocopherol, and EDTA affect lipid oxidation in fish oil enriched salad dressing differently. J Agric Food Chem (2007) 0.80
Acetate is a superior substrate for microbial fuel cell initiation preceding bioethanol effluent utilization. Appl Microbiol Biotechnol (2015) 0.80
Potential of phytase-mediated iron release from cereal-based foods: a quantitative view. Nutrients (2013) 0.80
Quantitative prediction of cell wall polysaccharide composition in grape (Vitis vinifera L.) and apple (Malus domestica) skins from acid hydrolysis monosaccharide profiles. J Agric Food Chem (2009) 0.79
Decrease in CD93 (C1qRp) expression in a human monocyte-like cell line (U937) treated with various apoptosis-inducing chemical substances. Microbiol Immunol (2007) 0.79
Th2 immune responses in GATA-3-transgenic mice infected with Heligmosomoides polygyrus. Int Arch Allergy Immunol (2003) 0.79
Tumor apoptosis in prostate cancer by PGD(2) and its metabolite 15d-PGJ(2) in murine model. Biomed Pharmacother (2012) 0.79
Modulation of chemokine expression on intestinal epithelial cells by Kampo (traditional Japanese herbal) medicine, Hochuekkito, and its active ingredients. J Nat Med (2012) 0.79
Enhancing RGI lyase thermostability by targeted single point mutations. Appl Microbiol Biotechnol (2013) 0.79
The significance of the initiation process parameters and reactor design for maximizing the efficiency of microbial fuel cells. Appl Microbiol Biotechnol (2014) 0.78
Application of an in vitro DNA protection assay to visualize stress mediation properties of the Dps protein. J Vis Exp (2013) 0.78
Backbone structures in human milk oligosaccharides: trans-glycosylation by metagenomic β-N-acetylhexosaminidases. Appl Microbiol Biotechnol (2015) 0.78
Impact of isolation method on the antioxidant activity of rapeseed meal phenolics. J Agric Food Chem (2004) 0.78
Photostability of natural orange-red and yellow fungal pigments in liquid food model systems. J Agric Food Chem (2009) 0.78