Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum.

PubWeight™: 0.94‹?›

🔗 View Article (PMC 3119305)

Published in Development on July 01, 2011

Authors

Tian Yu1, Yuichiro Yaguchi, Diego Echevarria, Salvador Martinez, M Albert Basson

Author Affiliations

1: Department of Craniofacial Development, King's College London, London, UK.

Articles citing this

The Fibroblast Growth Factor signaling pathway. Wiley Interdiscip Rev Dev Biol (2015) 1.82

Congenital hypoplasia of the cerebellum: developmental causes and behavioral consequences. Front Neuroanat (2013) 1.02

Deregulated FGF and homeotic gene expression underlies cerebellar vermis hypoplasia in CHARGE syndrome. Elife (2013) 1.00

MicroRNA-382 expression is elevated in the olfactory neuroepithelium of schizophrenia patients. Neurobiol Dis (2013) 0.97

Sprouty is a negative regulator of transforming growth factor β-induced epithelial-to-mesenchymal transition and cataract. Mol Med (2012) 0.95

Submandibular parasympathetic gangliogenesis requires sprouty-dependent Wnt signals from epithelial progenitors. Dev Cell (2015) 0.86

Localised inhibition of FGF signalling in the third pharyngeal pouch is required for normal thymus and parathyroid organogenesis. Development (2012) 0.83

Copy number variation in Han Chinese individuals with autism spectrum disorder. J Neurodev Disord (2014) 0.82

A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain. Development (2013) 0.80

FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One (2014) 0.80

The role of targeted protein degradation in early neural development. Genesis (2014) 0.79

The neuroanatomy of autism - a developmental perspective. J Anat (2016) 0.78

Fgf8-related secondary organizers exert different polarizing planar instructions along the mouse anterior neural tube. PLoS One (2012) 0.78

Signaling in cell differentiation and morphogenesis. Cold Spring Harb Perspect Biol (2012) 0.78

Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1. Elife (2014) 0.76

Activation of Wnt/β-catenin signalling affects differentiation of cells arising from the cerebellar ventricular zone. PLoS One (2012) 0.76

The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression. J Clin Invest (2017) 0.75

Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders. PLoS Genet (2017) 0.75

Articles cited by this

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat Genet (1999) 11.79

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. Neuron (1999) 7.80

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell (2000) 6.08

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem (2006) 5.78

Sonic hedgehog regulates the growth and patterning of the cerebellum. Development (1999) 4.78

Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development (2003) 3.88

Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development (1999) 3.84

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum. Curr Biol (1999) 3.55

Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes Dev (2000) 3.47

Mechanisms of neural patterning and specification in the developing cerebellum. Annu Rev Neurosci (1995) 3.26

Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors. Neuron (2005) 3.17

Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling. Trends Cell Biol (2005) 3.14

Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev Cell (2005) 2.95

Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling. Dev Cell (2005) 2.84

Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Dev Biol (2004) 2.77

A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J (1993) 2.73

Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit. Dev Dyn (2005) 2.71

ERM is required for transcriptional control of the spermatogonial stem cell niche. Nature (2005) 2.58

Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis. Dev Biol (2005) 2.41

Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation. Neuron (2001) 2.32

Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling. Dev Cell (2006) 2.27

Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain. Nature (1989) 2.23

Morphology, molecular codes, and circuitry produce the three-dimensional complexity of the cerebellum. Annu Rev Cell Dev Biol (2007) 2.19

Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain. Genes Dev (2005) 2.10

The leaving or Q fraction of the murine cerebral proliferative epithelium: a general model of neocortical neuronogenesis. J Neurosci (1996) 2.04

Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development (2004) 2.04

Midbrain development induced by FGF8 in the chick embryo. Nature (1996) 2.03

Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development. Development (2007) 2.01

Cellular and genetic regulation of the development of the cerebellar system. Prog Neurobiol (2004) 1.98

Cell cycle parameters and patterns of nuclear movement in the neocortical proliferative zone of the fetal mouse. J Neurosci (1993) 1.98

An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development (2007) 1.95

SDF-1 alpha induces chemotaxis and enhances Sonic hedgehog-induced proliferation of cerebellar granule cells. Development (2001) 1.94

The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. Development (2003) 1.88

FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. EMBO J (2003) 1.85

Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development (1997) 1.79

The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation. Development (2006) 1.79

Morphogenetic and cellular movements that shape the mouse cerebellum; insights from genetic fate mapping. Neuron (2005) 1.63

Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development. Development (1989) 1.60

Cell-cell interactions influence survival and differentiation of purified Purkinje cells in vitro. Neuron (1994) 1.56

Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development (1997) 1.54

Otx2, Gbx2 and Fgf8 interact to position and maintain a mid-hindbrain organizer. Curr Opin Cell Biol (2000) 1.53

FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Development (1999) 1.51

Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development. Development (2008) 1.43

Sprouty2 and Sprouty4 are essential for embryonic morphogenesis and regulation of FGF signaling. Biochem Biophys Res Commun (2006) 1.41

Fgf8 controls regional identity in the developing thalamus. Development (2008) 1.40

The compartmentalization of the cerebellum. Annu Rev Neurosci (1997) 1.39

Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors. Mol Cell Biol (2007) 1.38

A role for p27/Kip1 in the control of cerebellar granule cell precursor proliferation. J Neurosci (2000) 1.37

Conditional ablation of cerebellar astrocytes in postnatal transgenic mice. J Neurosci (1996) 1.37

FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Development (1999) 1.34

The rhombic lip and early cerebellar development. Curr Opin Neurobiol (2001) 1.33

In vitro neurite extension by granule neurons is dependent upon astroglial-derived fibroblast growth factor. Dev Biol (1988) 1.32

FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors. Development (2003) 1.27

Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells. Proc Natl Acad Sci U S A (2007) 1.24

Classical embryological studies and modern genetic analysis of midbrain and cerebellum development. Curr Top Dev Biol (2005) 1.19

Generation of Fgfr1 conditional knockout mice. Genesis (2002) 1.18

Bergmann fibers and granular cell migration in the cerebellum of homozygous weaver mutant mouse. Brain Res (1974) 1.17

Getting a first clue about SPRED functions. Bioessays (2007) 1.13

Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt). Development (1992) 1.11

The duration of Fgf8 isthmic organizer expression is key to patterning different tectal-isthmo-cerebellum structures. Development (2009) 1.05

Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum. Dev Biol (2009) 1.01

Mkp3 is a negative feedback modulator of Fgf8 signaling in the mammalian isthmic organizer. Dev Biol (2005) 1.00

Defects in specific associations between astroglia and neurons occur in microcultures of weaver mouse cerebellar cells. J Neurosci (1984) 0.98

The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway. Development (2004) 0.97

FGF signalling pathways in development of the midbrain and anterior hindbrain. J Neurochem (2007) 0.97

Transgenic mice expressing F3/contactin from the TAG-1 promoter exhibit developmentally regulated changes in the differentiation of cerebellar neurons. Development (2003) 0.97

Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn (2009) 0.95

Cellular and molecular mechanisms of cerebellar granule cell migration. Cell Biochem Biophys (2003) 0.90

The growth of the dendritic trees of Purkinje cells in irradiated agranular cerebellar cortex. Brain Res (1976) 0.90

Sprouty1 and Sprouty2 limit both the size of the otic placode and hindbrain Wnt8a by antagonizing FGF signaling. Dev Biol (2011) 0.89

Isthmus organizer for mesencephalon and metencephalon. Dev Growth Differ (2008) 0.89

Synergistic activity of Sef and Sprouty proteins in regulating the expression of Gbx2 in the mid-hindbrain region. Genesis (2005) 0.87

Fgf8 and Gbx2 induction concomitant with Otx2 repression is correlated with midbrain-hindbrain fate of caudal prosencephalon. Development (1999) 0.87

Regulation of isthmic Fgf8 signal by sprouty2. Development (2004) 0.84

Foxp4 is essential in maintenance of Purkinje cell dendritic arborization in the mouse cerebellum. Neuroscience (2010) 0.81

Down-regulated expression of glutamate transporter GLAST in Purkinje cell-associated astrocytes of reeler and weaver mutant cerebella. Neurosci Res (1999) 0.78

Studies of the dendritic tree of wild-type cerebellar Purkinje cells in lurcher chimeric mice. J Comp Neurol (1990) 0.77

Articles by these authors

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature (2008) 10.73

A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol (2011) 4.84

The aged niche disrupts muscle stem cell quiescence. Nature (2012) 3.46

Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling. Trends Cell Biol (2005) 3.14

Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers. Development (2006) 2.50

Increased LIS1 expression affects human and mouse brain development. Nat Genet (2009) 2.45

Sprouty1 regulates reversible quiescence of a self-renewing adult muscle stem cell pool during regeneration. Cell Stem Cell (2010) 2.03

An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development (2007) 1.95

The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. Development (2003) 1.88

A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development (2006) 1.79

Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development. Development (2011) 1.71

Periodic stripe formation by a Turing mechanism operating at growth zones in the mammalian palate. Nat Genet (2012) 1.60

Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea. Nat Med (2010) 1.50

Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development. Development (2008) 1.43

Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice. J Clin Invest (2009) 1.40

Inverse and direct cancer comorbidity in people with central nervous system disorders: a meta-analysis of cancer incidence in 577,013 participants of 50 observational studies. Psychother Psychosom (2014) 1.15

PITX2 is required for normal development of neurons in the mouse subthalamic nucleus and midbrain. Dev Biol (2004) 1.15

Thalamic development induced by Shh in the chick embryo. Dev Biol (2005) 1.12

Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm. Development (2009) 1.09

The development of the thalamic motor learning area is regulated by Fgf8 expression. J Neurosci (2009) 1.07

Sprouty proteins inhibit receptor-mediated activation of phosphatidylinositol-specific phospholipase C. Mol Biol Cell (2010) 1.06

Cellular and molecular basis of cerebellar development. Front Neuroanat (2013) 1.01

Molecular mechanisms controlling brain development: an overview of neuroepithelial secondary organizers. Int J Dev Biol (2010) 1.01

Mkp3 is a negative feedback modulator of Fgf8 signaling in the mammalian isthmic organizer. Dev Biol (2005) 1.00

Shh dependent and independent maintenance of basal midbrain. Mech Dev (2009) 1.00

Deregulated FGF and homeotic gene expression underlies cerebellar vermis hypoplasia in CHARGE syndrome. Elife (2013) 1.00

Cholesteatoma fibroblasts promote epithelial cell proliferation through overexpression of epiregulin. PLoS One (2013) 0.99

Middle ear hemangiona: a case report. Auris Nasus Larynx (2007) 0.97

The cephalic neural crest exerts a critical effect on forebrain and midbrain development. Proc Natl Acad Sci U S A (2006) 0.96

Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn (2009) 0.95

Loss of Sprouty1 rescues renal agenesis caused by Ret mutation. J Am Soc Nephrol (2008) 0.95

Sprouty is a negative regulator of transforming growth factor β-induced epithelial-to-mesenchymal transition and cataract. Mol Med (2012) 0.95

Itch-/- alphabeta and gammadelta T cells independently contribute to autoimmunity in Itchy mice. Blood (2008) 0.93

Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling. Neural Dev (2010) 0.93

Fate map of the diencephalon and the zona limitans at the 10-somites stage in chick embryos. Dev Biol (2004) 0.92

Comparison between endoscopic and microscopic stapes surgery. Laryngoscope (2013) 0.91

Fate map of the chick embryo neural tube. Dev Growth Differ (2009) 0.89

Modulation of Fgf8 activity during vertebrate brain development. Brain Res Brain Res Rev (2005) 0.88

Molecular regionalization of the diencephalon. Front Neurosci (2012) 0.88

Sprouty genes are essential for the normal development of epibranchial ganglia in the mouse embryo. Dev Biol (2011) 0.88

Dynamic expression patterns of Nkx6.1 and Nkx6.2 in the developing mes-diencephalic basal plate. Dev Dyn (2010) 0.88

Synergistic activity of Sef and Sprouty proteins in regulating the expression of Gbx2 in the mid-hindbrain region. Genesis (2005) 0.87

Live imaging of glioblastoma cells in brain tissue shows requirement of actin bundles for migration. Neuron Glia Biol (2006) 0.87

CHD7 maintains neural stem cell quiescence and prevents premature stem cell depletion in the adult hippocampus. Stem Cells (2015) 0.87

Sprouty1 haploinsufficiency prevents renal agenesis in a model of Fraser syndrome. J Am Soc Nephrol (2012) 0.86

Genetic tracing of subpopulation neurons in the prethalamus of mice (Mus musculus). J Comp Neurol (2009) 0.85

Expression of fibroblast growth factors (Fgfs) in murine tooth development. J Anat (2011) 0.85

Cerebellar oligodendroglial cells have a mesencephalic origin. Glia (2011) 0.85

Endoscope-assisted surgery via the middle cranial fossa approach for a petrous cholesteatoma. Auris Nasus Larynx (2008) 0.84

Experimental study of MAP kinase phosphatase-3 (Mkp3) expression in the chick neural tube in relation to Fgf8 activity. Brain Res Brain Res Rev (2005) 0.84

Adult stem cell therapy: dream or reality? Transpl Immunol (2006) 0.84

Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex (2012) 0.84

Reelin is overexpressed in the liver and plasma of bile duct ligated rats and its levels and glycosylation are altered in plasma of humans with cirrhosis. Int J Biochem Cell Biol (2008) 0.84

Wnt signal specifies the intrathalamic limit and its organizer properties by regulating Shh induction in the alar plate. J Neurosci (2013) 0.83

Localised inhibition of FGF signalling in the third pharyngeal pouch is required for normal thymus and parathyroid organogenesis. Development (2012) 0.83

Telencephalic morphogenesis during the process of neurulation: an experimental study using quail-chick chimeras. J Comp Neurol (2009) 0.82

Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development. J Neurosci (2014) 0.81

Pcp4l1, a novel gene encoding a Pcp4-like polypeptide, is expressed in specific domains of the developing brain. Gene Expr Patterns (2004) 0.81

Developmental dynamics of PAFAH1B subunits during mouse brain development. J Comp Neurol (2012) 0.80

Human adult periodontal ligament-derived cells integrate and differentiate after implantation into the adult mammalian brain. Cell Transplant (2012) 0.80

Roles of Wnt8a during formation and patterning of the mouse inner ear. Mech Dev (2012) 0.80

Stem cells from wildtype and Friedreich's ataxia mice present similar neuroprotective properties in dorsal root ganglia cells. PLoS One (2013) 0.79

Postnatal alterations of the inhibitory synaptic responses recorded from cortical pyramidal neurons in the Lis1/sLis1 mutant mouse. Mol Cell Neurosci (2007) 0.79

Pallial origin of basal forebrain cholinergic neurons in the nucleus basalis of Meynert and horizontal limb of the diagonal band nucleus. Development (2011) 0.78

Biallelic expression of Tbx1 protects the embryo from developmental defects caused by increased receptor tyrosine kinase signaling. Dev Dyn (2012) 0.78

Fgf8-related secondary organizers exert different polarizing planar instructions along the mouse anterior neural tube. PLoS One (2012) 0.78

Characterization of the functional properties of the neuroectoderm in mouse Cripto(-/-) embryos showing severe gastrulation defects. Int J Dev Biol (2009) 0.78

A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis. J Neurosci Methods (2010) 0.77

FGF ligands emerge as potential specifiers of synaptic identity. Cellscience (2010) 0.77

Endoderm-specific deletion of Tbx1 reveals an FGF-independent role for Tbx1 in pharyngeal apparatus morphogenesis. Dev Dyn (2014) 0.77

Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation. Glia (2014) 0.76

Stem cell injection in the hindlimb skeletal muscle enhances neurorepair in mice with spinal cord injury. Regen Med (2014) 0.76

Oligodendrocyte precursors originate in the parabasal band of the basal plate in prosomere 1 and migrate into the alar prosencephalon during chick development. Glia (2010) 0.76

The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression. J Clin Invest (2017) 0.75

FoxP1 Protein Shows Differential Layer Expression in the Parahippocampal Domain among Bird Species. Brain Behav Evol (2016) 0.75

Analysis of cCx39 expression pattern during chick development. Brain Res Dev Brain Res (2004) 0.75

[Petrous cholesteatoma: clinical features and surgical outcome]. Nihon Jibiinkoka Gakkai Kaiho (2008) 0.75

Creation of a cholesteatoma model using three-dimensional cultured skin equivalents. Laryngoscope (2005) 0.75

Corrigendum: Intraventricular injections of mesenchymal stem cells activate endogenous functional remyelination in a chronic demyelinating murine model. Cell Death Dis (2017) 0.75