Published in Methods Enzymol on January 01, 1990
Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages. Am J Pathol (1995) 2.09
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Human 2-oxoglutarate dehydrogenase complex E1 component forms a thiamin-derived radical by aerobic oxidation of the enamine intermediate. J Biol Chem (2014) 0.80
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Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components. Free Radic Biol Med (2015) 0.78
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The role of apoptosis in the cellular response of liver and spleen of BALB/c mice in cutaneous leishmaniasis. Iran J Med Sci (2015) 0.75
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The particulate superoxide-forming system from human neutrophils. Properties of the system and further evidence supporting its participation in the respiratory burst. J Clin Invest (1976) 2.43
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Subcellular localization of the superoxide-forming enzyme in human neutrophils. J Clin Invest (1979) 2.33
An inherited abnormality of neutrophil adhesion. Its genetic transmission and its association with a missing protein. N Engl J Med (1980) 2.32
Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase. Stroke (1997) 2.14
Infection with Pseudomonas cepacia in chronic granulomatous disease: role of nonoxidative killing by neutrophils in host defense. J Infect Dis (1994) 2.12
Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system. J Clin Invest (1985) 2.06
Defect in pyridine nucleotide dependent superoxide production by a particulate fraction from the cranulocytes of patients with chronic granulomatous disease. N Engl J Med (1975) 2.05
Genetic variants of chronic granulomatous disease: prevalence of deficiencies of two cytosolic components of the NADPH oxidase system. N Engl J Med (1989) 1.93
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Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease. J Clin Invest (1990) 1.91
Effects of anaerobiosis and inhibitors on O2-production by human granulocytes. Blood (1975) 1.85
cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils. J Biol Chem (1981) 1.75
Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558. J Biol Chem (1994) 1.74
Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase. J Biol Chem (1992) 1.69
Activation of neutrophil NADPH oxidase in a cell-free system. Partial purification of components and characterization of the activation process. J Biol Chem (1987) 1.68
Host defense molecule polymorphisms influence the risk for immune-mediated complications in chronic granulomatous disease. J Clin Invest (1998) 1.58
Effects of free fatty acids on release of superoxide and on change of shape by human neutrophils. Reversibility by albumin. J Biol Chem (1984) 1.57
Pyridine nucleotide-dependent superoxide production by a cell-free system from human granulocytes. J Clin Invest (1975) 1.57
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Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease. Blood (1989) 1.47
A missense mutation in the neutrophil cytochrome b heavy chain in cytochrome-positive X-linked chronic granulomatous disease. J Clin Invest (1989) 1.47
A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease. J Clin Invest (1997) 1.30
Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease. Proc Natl Acad Sci U S A (1991) 1.29
Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase. Mol Biol Cell (1993) 1.28
Spontaneous activation of NADPH oxidase in a cell-free system: unexpected multiple effects of magnesium ion concentrations. Biochem J (1999) 1.24
Fluoride-mediated activation of the respiratory burst in human neutrophils. A reversible process. J Clin Invest (1979) 1.23
Studies on the mechanism of superoxide release from human neutrophils stimulated with arachidonate. J Biol Chem (1984) 1.22
Activation of the respiratory burst oxidase in a fully soluble system from human neutrophils. J Biol Chem (1987) 1.22
Kinetics of activation of the respiratory burst oxidase in a fully soluble system from human neutrophils. J Biol Chem (1988) 1.21
Cytosolic components of the respiratory burst oxidase: resolution of four components, two of which are missing in complementing types of chronic granulomatous disease. Proc Natl Acad Sci U S A (1989) 1.20
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Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation. J Cereb Blood Flow Metab (2001) 1.16
Activation of neutrophil leukocytes: chemoattractant receptors and respiratory burst. FASEB J (1993) 1.15
Cytochrome b-245 of the neutrophil superoxide-generating system contains two nonidentical hemes. Potentiometric studies of a mutant form of gp91phox. J Biol Chem (1995) 1.15
Manganese-dependent NADPH oxidation by granulocyte particles. The role of superoxide and the nonphysiological nature of the manganese requirement. J Clin Invest (1976) 1.14
Association between gelatinase release and increased plasma membrane expression of the Mo1 glycoprotein. Blood (1987) 1.14
Respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils. J Clin Invest (1991) 1.13
Comparative aspects of oxidative metabolism of neutrophils from human blood and guinea pig peritonea: magnitude of the respiratory burst, dependence upon stimulating agents, and localization of the oxidases. J Cell Physiol (1980) 1.13
Studying X inactivation. Lancet (1992) 1.10
Resonance Raman and electron paramagnetic resonance structural investigations of neutrophil cytochrome b558. J Biol Chem (1991) 1.07
Assessment of the contribution of the cytochrome b moiety of the NADPH oxidase to the transmembrane H+ conductance of leukocytes. J Biol Chem (1994) 1.07
The cytosolic activating factors p47phox and p67phox have distinct roles in the regulation of electron flow in NADPH oxidase. J Biol Chem (1995) 1.06
The superoxide-generating system of human neutrophils possesses a novel diaphorase activity. Evidence for distinct regulation of electron flow within NADPH oxidase by p67-phox and p47-phox. J Biol Chem (1994) 1.05
Development of a H(+)-selective conductance during granulocytic differentiation of HL-60 cells. Am J Physiol (1994) 1.04
Neutrophil-mediated solubilization of the subendothelial matrix: oxidative and nonoxidative mechanisms of proteolysis used by normal and chronic granulomatous disease phagocytes. J Immunol (1986) 1.02
Immunocytochemical localization on O2-sensing protein (NADPH oxidase) in chemoreceptor cells. Microsc Res Tech (1997) 1.02
Human neutrophil laminin receptors: activation-dependent receptor expression. J Immunol (1987) 1.01
Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558. J Clin Invest (1994) 1.00
Recombination events between the p47-phox gene and its highly homologous pseudogenes are the main cause of autosomal recessive chronic granulomatous disease. Blood (2000) 1.00
Absolute requirement for GTP in activation of human neutrophil NADPH oxidase in a cell-free system: role of ATP in regenerating GTP. Proc Natl Acad Sci U S A (1992) 1.00
Prolonged recombinant interferon-gamma therapy in chronic granulomatous disease: evidence against enhanced neutrophil oxidase activity. Blood (1992) 1.00
Inhibition of collagen deposition in the extracellular matrix prevents the establishment of a stroma supportive of hematopoiesis in long-term murine bone marrow cultures. J Clin Invest (1985) 0.98
Cytochalasin E diminishes the lag phase in the release of superoxide by human neutrophils. Biochem Biophys Res Commun (1982) 0.98
Retinoids stimulate the release of superoxide by neutrophils and change their morphology. J Cell Physiol (1986) 0.96
A new X-linked variant of chronic granulomatous disease characterized by the existence of a normal clone of respiratory burst-competent phagocytic cells. Blood (1995) 0.95
Stabilization of human neutrophil NADPH oxidase activated in a cell-free system by cytosolic proteins and by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide. J Biol Chem (1992) 0.95
1,2-dioctanoyl-sn-glycerol can stimulate neutrophils by different mechanisms. Evidence for a pathway that does not involve phosphorylation of the 47-kDa protein. J Biol Chem (1989) 0.95
The p67-phox cytosolic peptide of the respiratory burst oxidase from human neutrophils. Functional aspects. J Clin Invest (1990) 0.94
The mechanism of activation of NADPH oxidase in the cell-free system: the activation process is primarily catalytic and not through the formation of a stoichiometric complex. Biochem J (1999) 0.94
Simultaneous presence of p47(phox) and flavocytochrome b-245 are required for the activation of NADPH oxidase by anionic amphiphiles. Evidence for an intermediate state of oxidase activation. J Biol Chem (1999) 0.94
Molecular analysis of 9 new families with chronic granulomatous disease caused by mutations in CYBA, the gene encoding p22(phox). Blood (2000) 0.94
Regulation of NADPH oxidase activity by Rac GTPase activating protein(s). Mol Biol Cell (1993) 0.93
Abnormal activation of H+ conductance in NADPH oxidase-defective neutrophils. Proc Natl Acad Sci U S A (1993) 0.93
Activation of H+ conductance in neutrophils requires assembly of components of the respiratory burst oxidase but not its redox function. J Clin Invest (1994) 0.93
Activation of human neutrophil NADPH-oxidase in vitro by the catalytic fragment of protein kinase-C. Biochem Biophys Res Commun (1989) 0.92
Defective neutrophil adhesion due to an inherited deficiency of a specific glycoprotein. Trans Assoc Am Physicians (1980) 0.92
Experimental histoplasmosis in mice treated with anti-murine interferon-gamma antibody and in interferon-gamma gene knockout mice. Microbes Infect (2000) 0.91
Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA. J Exp Med (1993) 0.91
Staurosporine inhibits the soluble and membrane-bound protein tyrosine kinases of human neutrophils. Biochem Biophys Res Commun (1991) 0.91
Identification of a thermolabile component of the human neutrophil NADPH oxidase. A model for chronic granulomatous disease caused by deficiency of the p67-phox cytosolic component. J Clin Invest (1992) 0.91
Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid. J Biol Chem (1999) 0.90
Identification of the NADPH-binding subunit of the respiratory burst oxidase. J Biol Chem (1991) 0.89
The enzyme of granulocytes that produces superoxide and peroxide. An elusive Pimpernel. N Engl J Med (1979) 0.87
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Evidence that de novo protein synthesis participates in a time-dependent augmentation of the chemotactic peptide-induced respiratory burst in neutrophils. Effects of recombinant human colony stimulating factors and dihydrocytochalasin B. Free Radic Biol Med (1988) 0.86
Metabolism of procainamide to the cytotoxic hydroxylamine by neutrophils activated in vitro. J Clin Invest (1989) 0.86
Molecular analysis of chronic granulomatous disease caused by defects in gp91-phox. Hum Mutat (1999) 0.85
Autosomal recessive chronic granulomatous disease caused by novel mutations in NCF-2, the gene encoding the p67-phox component of phagocyte NADPH oxidase. Hum Genet (1999) 0.85
Chronic granulomatous disease: diagnosis and classification at the molecular level. Clin Lab Med (1992) 0.84
A variant X-linked chronic granulomatous disease patient (X91+) with partially functional cytochrome b. J Biol Chem (1995) 0.83
Hematologically important mutations: the autosomal recessive forms of chronic granulomatous disease (first update). Blood Cells Mol Dis (2000) 0.83