Published in J Biol Chem on May 05, 1992
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol (1996) 11.04
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J (1996) 5.14
The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. EMBO J (1996) 5.09
Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J Cell Biol (1997) 4.27
Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI). J Cell Biol (1993) 3.87
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J Cell Biol (1994) 3.65
A role for Rho in Ras transformation. Proc Natl Acad Sci U S A (1995) 3.59
Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J Cell Biol (1999) 3.43
Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae. J Cell Biol (1994) 2.74
Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility. Mol Cell Biol (1993) 2.71
Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP binding protein, rho. J Cell Biol (1993) 2.26
Inhibition of Pollen Tube Elongation by Microinjected Anti-Rop1Ps Antibodies Suggests a Crucial Role for Rho-Type GTPases in the Control of Tip Growth. Plant Cell (1997) 2.24
Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility. J Cell Biol (1999) 2.17
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Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA. Genes Dev (2001) 1.94
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Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle. J Physiol (2003) 1.86
Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase. J Cell Biol (1998) 1.85
Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum. J Physiol (2000) 1.71
RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs. Mol Biol Cell (1998) 1.66
Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase. Biochem J (2002) 1.60
The low molecular mass GTP-binding protein Rho is affected by toxin A from Clostridium difficile. J Clin Invest (1995) 1.51
The Rho family G proteins play a critical role in muscle differentiation. Mol Cell Biol (1998) 1.47
Possible involvement of the novel CPI-17 protein in protein kinase C signal transduction of rabbit arterial smooth muscle. J Physiol (1998) 1.46
Agonist-induced changes in the phosphorylation of the myosin- binding subunit of myosin light chain phosphatase and CPI17, two regulatory factors of myosin light chain phosphatase, in smooth muscle. Biochem J (2003) 1.38
Involvement of the GTP binding protein Rho in constitutive endocytosis in Xenopus laevis oocytes. J Cell Biol (1995) 1.36
Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle. J Physiol (1996) 1.32
A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly. EMBO J (1993) 1.31
Differential localization of myosin and myosin phosphatase subunits in smooth muscle cells and migrating fibroblasts. Mol Biol Cell (1997) 1.30
Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF. J Cell Biol (2001) 1.26
A major role for the rho-associated coiled coil forming protein kinase in G-protein-mediated Ca2+ sensitization through inhibition of myosin phosphatase in rabbit trachea. Br J Pharmacol (1999) 1.21
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Clostridium difficile toxin B inhibits carbachol-induced force and myosin light chain phosphorylation in guinea-pig smooth muscle: role of Rho proteins. J Physiol (1998) 1.15
RhoA interacts with the fusion glycoprotein of respiratory syncytial virus and facilitates virus-induced syncytium formation. J Virol (1999) 1.14
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Conditional lethality of a yeast strain expressing human RHOA in place of RHO1. Proc Natl Acad Sci U S A (1994) 1.13
Antiviral activity of lovastatin against respiratory syncytial virus in vivo and in vitro. Antimicrob Agents Chemother (2001) 1.08
Rho-dependent kinase is involved in agonist-activated calcium entry in rat arteries. J Physiol (2003) 1.04
Augmented agonist-induced Ca(2+)-sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells. J Clin Invest (1994) 1.03
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Mechanisms of Ca2+ sensitization of force production by noradrenaline in rat mesenteric small arteries. J Physiol (1998) 1.01
Essential role of rho kinase in the Ca2+ sensitization of prostaglandin F(2alpha)-induced contraction of rabbit aortae. J Physiol (2003) 1.01
Pericyte Rho GTPase mediates both pericyte contractile phenotype and capillary endothelial growth state. Am J Pathol (2007) 1.00
Role of transglutaminase II in retinoic acid-induced activation of RhoA-associated kinase-2. EMBO J (2001) 0.97
RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension. Vasc Health Risk Manag (2009) 0.96
Enhanced contractile response to thrombin in the pregnant rat myometrium. Br J Pharmacol (2000) 0.95
Suppression of airway hyperresponsiveness induced by ovalbumin sensitisation and RSV infection with Y-27632, a Rho kinase inhibitor. Thorax (2002) 0.94
The effects of the small GTPase RhoA on the muscarinic contraction of airway smooth muscle result from its role in regulating actin polymerization. Am J Physiol Cell Physiol (2010) 0.94
Involvement of RhoA-mediated Ca2+ sensitization in antigen-induced bronchial smooth muscle hyperresponsiveness in mice. Respir Res (2005) 0.94
The Rho-related protein Rnd1 inhibits Ca2+ sensitization of rat smooth muscle. J Physiol (1999) 0.93
Increase in tone and intracellular Ca2+ in rabbit isolated ear artery by platelet-derived growth factor. Br J Pharmacol (1995) 0.92
Localization and translocation of RhoA protein in the human gastric cancer cell line SGC-7901. World J Gastroenterol (2008) 0.91
ADP-ribosylation of Rho proteins by Clostridium botulinum exoenzyme C3 is influenced by phosphorylation of Rho-associated factors. Biochem J (1994) 0.90
Changes in the mechanisms involved in uterine contractions during pregnancy in guinea-pigs. J Physiol (2000) 0.87
Down-regulation of G-protein-mediated Ca2+ sensitization in smooth muscle. Mol Biol Cell (1997) 0.86
RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells. J Cell Sci (2015) 0.86
Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors. J Biol Chem (2015) 0.85
Effect of a peptide inhibitor of protein kinase C on G-protein-mediated increase in myofilament Ca(2+)-sensitivity in rabbit arterial skinned muscle. Br J Pharmacol (1994) 0.85
Mechanisms of vasoconstriction induced by endothelin-1 in smooth muscle of rabbit mesenteric artery. J Physiol (1994) 0.85
DEK depletion negatively regulates Rho/ROCK/MLC pathway in non-small cell lung cancer. J Histochem Cytochem (2013) 0.84
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ADP-ribosylation of the GTP-binding protein RhoA blocks cytoplasmic division in human myelomonocytic cells. Biochem J (1995) 0.83
Angiotensin II and JAK2 put on the pressure. Nat Med (2010) 0.81
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Protein kinase C-independent sensitization of contractile proteins to Ca2+ in alpha-toxin-permeabilized smooth muscle cells from the guinea-pig stomach. Br J Pharmacol (1992) 0.81
Resting load regulates cytosolic calcium-force relationship of the contraction of bovine cerebrovascular smooth muscle. J Physiol (1995) 0.80
Inhibition of smooth-muscle myosin-light-chain phosphatase by Ruthenium Red. Biochem J (2000) 0.80
Increased cytoplasmic localization of p27(kip1) and its modulation of RhoA activity during progression of chronic myeloid leukemia. PLoS One (2013) 0.79
Effects of glyceollin I on vascular contraction in rat aorta. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.76
Pulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-kappaB activation. Biochem Biophys Res Commun (2008) 0.75
A close look at the contraction and relaxation of the myometrium; the role of calcium. J Turk Ger Gynecol Assoc (2013) 0.75
First insight into the proteome landscape of the porcine short posterior ciliary arteries: Key signalling pathways maintaining physiologic functions. Sci Rep (2016) 0.75
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Effects of gomisin A on vascular contraction in rat aortic rings. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.75
C2-ceramide induces vasodilation in phenylephrine-induced pre-contracted rat thoracic aorta: role of RhoA/Rho-kinase and intracellular Ca2+ concentration. Naunyn Schmiedebergs Arch Pharmacol (2005) 0.75
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Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem (1982) 16.71
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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. EMBO J (1998) 7.59
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Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science (1997) 5.80
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