An in vitro system for the leader-primed transcription of coronavirus mRNAs.

PubWeight™: 1.69‹?› | Rank: Top 3%

🔗 View Article (PMC 552193)

Published in EMBO J on December 01, 1990

Authors

S C Baker1, M M Lai

Author Affiliations

1: Howard Hughes Medical Institute, Department of Microbiology, University of Southern California School of Medicine, Los Angeles 90033.

Articles citing this

RNA recombination in animal and plant viruses. Microbiol Rev (1992) 5.05

Arterivirus discontinuous mRNA transcription is guided by base pairing between sense and antisense transcription-regulating sequences. Proc Natl Acad Sci U S A (1999) 2.42

A system for study of coronavirus mRNA synthesis: a regulated, expressed subgenomic defective interfering RNA results from intergenic site insertion. J Virol (1991) 2.30

Subgenomic RNA synthesis directed by a synthetic defective interfering RNA of mouse hepatitis virus: a study of coronavirus transcription initiation. J Virol (1994) 1.85

Sequence requirements for RNA strand transfer during nidovirus discontinuous subgenomic RNA synthesis. EMBO J (2001) 1.75

Genetics of mouse hepatitis virus transcription: evidence that subgenomic negative strands are functional templates. J Virol (1994) 1.72

A cis-acting function for the coronavirus leader in defective interfering RNA replication. J Virol (1994) 1.68

The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor. J Virol (2004) 1.67

Mechanism of coronavirus transcription: duration of primary transcription initiation activity and effects of subgenomic RNA transcription on RNA replication. J Virol (1992) 1.61

Coronavirus leader RNA regulates and initiates subgenomic mRNA transcription both in trans and in cis. J Virol (1994) 1.58

The fitness of defective interfering murine coronavirus DI-a and its derivatives is decreased by nonsense and frameshift mutations. J Virol (1992) 1.49

Generation and analysis of nonhomologous RNA-RNA recombinants in brome mosaic virus: sequence complementarities at crossover sites. J Virol (1991) 1.48

Subgenomic negative-strand RNA function during mouse hepatitis virus infection. J Virol (2000) 1.48

Mutagenic analysis of the coronavirus intergenic consensus sequence. J Virol (1992) 1.45

Effect of intergenic consensus sequence flanking sequences on coronavirus transcription. J Virol (1993) 1.44

Equine arteritis virus subgenomic mRNA synthesis: analysis of leader-body junctions and replicative-form RNAs. J Virol (1996) 1.43

The UCUAAAC promoter motif is not required for high-frequency leader recombination in bovine coronavirus defective interfering RNA. J Virol (1996) 1.35

Identification of mouse hepatitis virus papain-like proteinase 2 activity. J Virol (2000) 1.34

Dissecting RNA recombination in vitro: role of RNA sequences and the viral replicase. EMBO J (1998) 1.34

Polypyrimidine tract-binding protein binds to the leader RNA of mouse hepatitis virus and serves as a regulator of viral transcription. J Virol (1999) 1.28

Characterization of an equine arteritis virus replicase mutant defective in subgenomic mRNA synthesis. J Virol (1999) 1.22

Unusual heterogeneity of leader-mRNA fusion in a murine coronavirus: implications for the mechanism of RNA transcription and recombination. J Virol (1994) 1.21

Evidence for coronavirus discontinuous transcription. J Virol (1994) 1.20

The effect of two closely inserted transcription consensus sequences on coronavirus transcription. J Virol (1995) 1.13

Map locations of mouse hepatitis virus temperature-sensitive mutants: confirmation of variable rates of recombination. J Virol (1994) 1.08

Coronavirus mRNA transcription: UV light transcriptional mapping studies suggest an early requirement for a genomic-length template. J Virol (1992) 1.07

RNA recombination in a coronavirus: recombination between viral genomic RNA and transfected RNA fragments. J Virol (1992) 1.03

Bovine coronavirus 5'-proximal genomic acceptor hotspot for discontinuous transcription is 65 nucleotides wide. J Virol (2006) 0.95

Function of a 5'-end genomic RNA mutation that evolves during persistent mouse hepatitis virus infection in vitro. J Virol (1995) 0.93

The leader RNA of coronavirus mouse hepatitis virus contains an enhancer-like element for subgenomic mRNA transcription. J Virol (2000) 0.89

A 5'-proximal RNA sequence of murine coronavirus as a potential initiation site for genomic-length mRNA transcription. J Virol (1996) 0.82

Articles cited by this

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (1988) 220.77

A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes. Proc Natl Acad Sci U S A (1985) 46.59

A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription. Cell (1981) 8.09

A trans-spliced leader sequence on actin mRNA in C. elegans. Cell (1987) 7.24

A model for RNA editing in kinetoplastid mitochondria: "guide" RNA molecules transcribed from maxicircle DNA provide the edited information. Cell (1990) 6.24

Evidence for trans splicing in trypanosomes. Cell (1986) 5.58

Identification of a novel Y branch structure as an intermediate in trypanosome mRNA processing: evidence for trans splicing. Cell (1986) 4.31

Coronavirus transcription: subgenomic mouse hepatitis virus replicative intermediates function in RNA synthesis. J Virol (1990) 4.19

Mouse hepatitis virus A59: mRNA structure and genetic localization of the sequence divergence from hepatotropic strain MHV-3. J Virol (1981) 4.00

Characterization of leader RNA sequences on the virion and mRNAs of mouse hepatitis virus, a cytoplasmic RNA virus. Proc Natl Acad Sci U S A (1984) 3.81

Coronavirus subgenomic minus-strand RNAs and the potential for mRNA replicons. Proc Natl Acad Sci U S A (1989) 3.65

The virus-specific intracellular RNA species of two murine coronaviruses: MHV-a59 and MHV-JHM. Virology (1981) 3.57

Coronavirus genome: prediction of putative functional domains in the non-structural polyprotein by comparative amino acid sequence analysis. Nucleic Acids Res (1989) 3.38

Coronavirus mRNA synthesis involves fusion of non-contiguous sequences. EMBO J (1983) 3.13

Presence of leader sequences in the mRNA of mouse hepatitis virus. J Virol (1983) 3.06

Replication of mouse hepatitis virus: negative-stranded RNA and replicative form RNA are of genome length. J Virol (1982) 2.86

Completion of the sequence of the genome of the coronavirus avian infectious bronchitis virus. J Gen Virol (1987) 2.84

La Crosse virions contain a primer-stimulated RNA polymerase and a methylated cap-dependent endonuclease. J Virol (1984) 2.80

Characterization of replicative intermediate RNA of mouse hepatitis virus: presence of leader RNA sequences on nascent chains. J Virol (1983) 2.80

Molecular cloning of the gene encoding the putative polymerase of mouse hepatitis coronavirus, strain A59. Virology (1989) 2.69

Characterization of two RNA polymerase activities induced by mouse hepatitis virus. J Virol (1982) 2.46

The 5'-end sequence of the murine coronavirus genome: implications for multiple fusion sites in leader-primed transcription. Virology (1987) 2.17

Leader sequences of murine coronavirus mRNAs can be freely reassorted: evidence for the role of free leader RNA in transcription. Proc Natl Acad Sci U S A (1986) 2.16

The replication of murine coronaviruses in enucleated cells. Virology (1981) 2.14

Characterization of leader-related small RNAs in coronavirus-infected cells: further evidence for leader-primed mechanism of transcription. Virus Res (1985) 2.07

Evidence for in vivo trans splicing of pre-mRNAs in tobacco chloroplasts. Cell (1987) 2.00

Host cell nuclear function and murine hepatitis virus replication. J Gen Virol (1981) 2.00

High-frequency leader sequence switching during coronavirus defective interfering RNA replication. J Virol (1989) 1.95

Initiation and replication of vesicular stomatitis virus genome RNA in a cell-free system. Proc Natl Acad Sci U S A (1983) 1.95

Sequence and translation of the murine coronavirus 5'-end genomic RNA reveals the N-terminal structure of the putative RNA polymerase. J Virol (1987) 1.89

Primary structure and translation of a defective interfering RNA of murine coronavirus. Virology (1988) 1.87

Identification of a domain required for autoproteolytic cleavage of murine coronavirus gene A polyprotein. J Virol (1989) 1.82

Identification of a new transcriptional initiation site and the corresponding functional gene 2b in the murine coronavirus RNA genome. J Virol (1989) 1.77

Discontinuous transcription generates heterogeneity at the leader fusion sites of coronavirus mRNAs. J Virol (1988) 1.76

Further characterization of mouse hepatitis virus RNA-dependent RNA polymerases. Virology (1984) 1.64

In vitro replication of Sendai virus wild-type and defective interfering particle genome RNAs. J Virol (1985) 1.53

Analysis of intracellular small RNAs of mouse hepatitis virus: evidence for discontinuous transcription. Virology (1987) 1.52

Identification of putative polymerase gene product in cells infected with murine coronavirus A59. Virology (1987) 1.48

A hepatitis virus complicating studies with mouse leukemia. J Natl Cancer Inst (1961) 1.45

Differential premature termination of transcription as a proposed mechanism for the regulation of coronavirus gene expression. Nucleic Acids Res (1988) 1.40

Articles by these authors

(truncated to the top 100)

Continuous tissue culture cell lines derived from chemically induced tumors of Japanese quail. Cell (1977) 7.23

Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein. Science (1999) 6.21

Molecular cloning and sequencing of a human hepatitis delta (delta) virus RNA. Nature (1987) 4.52

Adenylic acid-rich sequence in RNAs of Rous sarcoma virus and Rauscher mouse leukaemia virus. Nature (1972) 4.49

RNA of mouse hepatitis virus. J Virol (1978) 4.27

The complete sequence (22 kilobases) of murine coronavirus gene 1 encoding the putative proteases and RNA polymerase. Virology (1991) 4.07

Mouse hepatitis virus A59: mRNA structure and genetic localization of the sequence divergence from hepatotropic strain MHV-3. J Virol (1981) 4.00

Characterization of leader RNA sequences on the virion and mRNAs of mouse hepatitis virus, a cytoplasmic RNA virus. Proc Natl Acad Sci U S A (1984) 3.81

Human hepatitis delta virus RNA subfragments contain an autocleavage activity. Proc Natl Acad Sci U S A (1989) 3.51

Avian tumor virus RNA: a comparison of three sarcoma viruses and their transformation-defective derivatives by oligonucleotide fingerprinting and DNA-RNA hybridization. Proc Natl Acad Sci U S A (1973) 3.46

Ribonucleic acid components of murine sarcoma and leukemia viruses. Proc Natl Acad Sci U S A (1973) 3.42

Putative papain-related thiol proteases of positive-strand RNA viruses. Identification of rubi- and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi-, alpha- and coronaviruses. FEBS Lett (1991) 3.35

Human hepatitis delta antigen is a nuclear phosphoprotein with RNA-binding activity. J Virol (1988) 3.11

Presence of leader sequences in the mRNA of mouse hepatitis virus. J Virol (1983) 3.06

High-frequency RNA recombination of murine coronaviruses. J Virol (1986) 2.91

Replication of mouse hepatitis virus: negative-stranded RNA and replicative form RNA are of genome length. J Virol (1982) 2.86

Characterization of replicative intermediate RNA of mouse hepatitis virus: presence of leader RNA sequences on nascent chains. J Virol (1983) 2.80

Characterization of two RNA polymerase activities induced by mouse hepatitis virus. J Virol (1982) 2.46

The 3'-untranslated region of hepatitis C virus RNA enhances translation from an internal ribosomal entry site. J Virol (1998) 2.36

Further characterization of mRNA's of mouse hepatitis virus: presence of common 5'-end nucleotides. J Virol (1982) 2.34

Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein. Virology (1999) 2.33

Comparative analysis of RNA genomes of mouse hepatitis viruses. J Virol (1981) 2.30

Restriction enzyme sites on the avian RNA tumor virus genome. J Virol (1978) 2.29

Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis. J Virol (1998) 2.28

Determination of the secondary structure of and cellular protein binding to the 3'-untranslated region of the hepatitis C virus RNA genome. J Virol (1997) 2.28

Occurrence of partial deletion and substitution of the src gene in the RNA genome of avian sarcoma virus. Proc Natl Acad Sci U S A (1977) 2.22

Recombination between nonsegmented RNA genomes of murine coronaviruses. J Virol (1985) 2.21

The 5'-end sequence of the murine coronavirus genome: implications for multiple fusion sites in leader-primed transcription. Virology (1987) 2.17

Characterization of hepatitis delta antigen: specific binding to hepatitis delta virus RNA. J Virol (1990) 2.17

Leader sequences of murine coronavirus mRNAs can be freely reassorted: evidence for the role of free leader RNA in transcription. Proc Natl Acad Sci U S A (1986) 2.16

A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA. J Virol (1999) 2.16

Antigenic relationships of murine coronaviruses: analysis using monoclonal antibodies to JHM (MHV-4) virus. Virology (1983) 2.11

Phosphoproteins of murine hepatitis viruses. J Virol (1979) 2.07

Characterization of leader-related small RNAs in coronavirus-infected cells: further evidence for leader-primed mechanism of transcription. Virus Res (1985) 2.07

High-frequency leader sequence switching during coronavirus defective interfering RNA replication. J Virol (1989) 1.95

An internal polypyrimidine-tract-binding protein-binding site in the hepatitis C virus RNA attenuates translation, which is relieved by the 3'-untranslated sequence. Virology (1999) 1.90

Sequence and translation of the murine coronavirus 5'-end genomic RNA reveals the N-terminal structure of the putative RNA polymerase. J Virol (1987) 1.89

Analysis of efficiently packaged defective interfering RNAs of murine coronavirus: localization of a possible RNA-packaging signal. J Virol (1990) 1.88

Primary structure and translation of a defective interfering RNA of murine coronavirus. Virology (1988) 1.87

Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor. J Virol (1997) 1.84

Identification of a domain required for autoproteolytic cleavage of murine coronavirus gene A polyprotein. J Virol (1989) 1.82

Identification of a new transcriptional initiation site and the corresponding functional gene 2b in the murine coronavirus RNA genome. J Virol (1989) 1.77

Discontinuous transcription generates heterogeneity at the leader fusion sites of coronavirus mRNAs. J Virol (1988) 1.76

Mouse hepatitis virus utilizes two carcinoembryonic antigens as alternative receptors. J Virol (1992) 1.75

Identification of the catalytic sites of a papain-like cysteine proteinase of murine coronavirus. J Virol (1993) 1.74

Differential subcellular localization of hepatitis C virus core gene products. Virology (1995) 1.73

Defective-interfering particles of murine coronavirus: mechanism of synthesis of defective viral RNAs. Virology (1988) 1.73

Deletion mapping of a mouse hepatitis virus defective interfering RNA reveals the requirement of an internal and discontiguous sequence for replication. J Virol (1993) 1.71

Heterogeneous nuclear ribonucleoprotein A1 binds to the transcription-regulatory region of mouse hepatitis virus RNA. Proc Natl Acad Sci U S A (1997) 1.70

Genome of avian myelocytomatosis virus MC29: analysis by heteroduplex mapping. Proc Natl Acad Sci U S A (1979) 1.68

Phosphoproteins of Rous sarcoma viruses. Virology (1976) 1.67

Colocalization and membrane association of murine hepatitis virus gene 1 products and De novo-synthesized viral RNA in infected cells. J Virol (1999) 1.67

Differences between the envelope glycoproteins and glycopeptides of avian tumor viruses released from transformed and from nontransformed cells. Virology (1972) 1.67

Further characterization of mouse hepatitis virus RNA-dependent RNA polymerases. Virology (1984) 1.64

Three different cellular proteins bind to complementary sites on the 5'-end-positive and 3'-end-negative strands of mouse hepatitis virus RNA. J Virol (1993) 1.64

Identification of the cis-acting signal for minus-strand RNA synthesis of a murine coronavirus: implications for the role of minus-strand RNA in RNA replication and transcription. J Virol (1994) 1.64

Characterization of nuclear targeting signal of hepatitis delta antigen: nuclear transport as a protein complex. J Virol (1992) 1.63

Murine coronaviruses: isolation and characterization of two plaque morphology variants of the JHM neurotropic strain. J Gen Virol (1982) 1.62

Heterogeneity of gene expression of the hemagglutinin-esterase (HE) protein of murine coronaviruses. Virology (1991) 1.60

Reversible cleavage and ligation of hepatitis delta virus RNA. Science (1989) 1.59

Coronavirus leader RNA regulates and initiates subgenomic mRNA transcription both in trans and in cis. J Virol (1994) 1.58

Random nature of coronavirus RNA recombination in the absence of selection pressure. Virology (1991) 1.57

RNA-binding activity of hepatitis delta antigen involves two arginine-rich motifs and is required for hepatitis delta virus RNA replication. J Virol (1993) 1.57

Sequence conservation and divergence of hepatitis delta virus RNA. Virology (1990) 1.56

Analysis of intracellular small RNAs of mouse hepatitis virus: evidence for discontinuous transcription. Virology (1987) 1.52

Transcription of hepatitis delta antigen mRNA continues throughout hepatitis delta virus (HDV) replication: a new model of HDV RNA transcription and replication. J Virol (1998) 1.51

Homotypic interaction and multimerization of hepatitis C virus core protein. Virology (1996) 1.51

Template requirement and initiation site selection by hepatitis C virus polymerase on a minimal viral RNA template. J Biol Chem (2000) 1.46

Sequence and structure of the catalytic RNA of hepatitis delta virus genomic RNA. J Mol Biol (1992) 1.44

17-year follow-up of a randomized prospective controlled trial of adjuvant intravesical doxorubicin in the treatment of superficial bladder cancer. Int Braz J Urol (2005) 1.44

Evolution of the 5'-end of genomic RNA of murine coronaviruses during passages in vitro. Virology (1989) 1.43

Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling. Science (1999) 1.42

Immunophilins in the nervous system. Neuron (1998) 1.42

Requirement of the 5'-end genomic sequence as an upstream cis-acting element for coronavirus subgenomic mRNA transcription. J Virol (1994) 1.41

Heterogeneous nuclear ribonucleoprotein a1 binds to the 3'-untranslated region and mediates potential 5'-3'-end cross talks of mouse hepatitis virus RNA. J Virol (2001) 1.41

Heterogeneous nuclear ribonucleoprotein A1 regulates RNA synthesis of a cytoplasmic virus. EMBO J (2000) 1.38

Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton. Proc Natl Acad Sci U S A (1998) 1.38

Neuropathogenicity of mouse hepatitis virus JHM isolates differing in hemagglutinin-esterase protein expression. J Neurovirol (1995) 1.37

RNA-Dependent replication and transcription of hepatitis delta virus RNA involve distinct cellular RNA polymerases. Mol Cell Biol (2000) 1.36

A pregnancy-specific glycoprotein is expressed in the brain and serves as a receptor for mouse hepatitis virus. Proc Natl Acad Sci U S A (1995) 1.34

Replication of hepatitis delta virus RNA: effect of mutations of the autocatalytic cleavage sites. J Virol (1993) 1.34

Hepatitis C virus NS5B protein is a membrane-associated phosphoprotein with a predominantly perinuclear localization. Virology (1997) 1.33

In vivo RNA-RNA recombination of coronavirus in mouse brain. J Virol (1988) 1.33

Chromosome 1 contains the endogenous RAV-0 retrovirus sequences in chicken cells. Proc Natl Acad Sci U S A (1979) 1.32

Multiple recombination sites at the 5'-end of murine coronavirus RNA. Virology (1987) 1.32

Oligomerization of hepatitis delta antigen is required for both the trans-activating and trans-dominant inhibitory activities of the delta antigen. J Virol (1992) 1.32

Hepatitis C virus core protein interacts with heterogeneous nuclear ribonucleoprotein K. J Biol Chem (1998) 1.32

RNA conformational requirements of self-cleavage of hepatitis delta virus RNA. Mol Cell Biol (1990) 1.30

Avian erythroblastosis virus: transformation-specific sequences form a contiguous segment of 3.25 kb located in the middle of the 6-kb genome. Virology (1979) 1.29

In vitro synthesis and characterisation of full- and half-genome length complementary DNA from avian oncoviruses. Nature (1978) 1.29

Polypyrimidine tract-binding protein binds to the leader RNA of mouse hepatitis virus and serves as a regulator of viral transcription. J Virol (1999) 1.28

Sequence analysis of nucleocapsid gene and leader RNA of human coronavirus OC43. Virus Res (1989) 1.27

Linezolid-induced optic neuropathy: a mitochondrial disorder? Br J Ophthalmol (2007) 1.26

Avian reticuloendotheliosis virus contains a new class of oncogene of turkey origin. Virology (1981) 1.26

Mouse hepatitis virus S RNA sequence reveals that nonstructural proteins ns4 and ns5a are not essential for murine coronavirus replication. J Virol (1991) 1.25

A pseudoknot ribozyme structure is active in vivo and required for hepatitis delta virus RNA replication. J Virol (1996) 1.25

Heterogeneity of hepatitis delta antigen. Virology (1990) 1.23

The receptor for mouse hepatitis virus in the resistant mouse strain SJL is functional: implications for the requirement of a second factor for viral infection. J Virol (1992) 1.22

Recommendations of the Coronavirus Study Group for the nomenclature of the structural proteins, mRNAs, and genes of coronaviruses. Virology (1990) 1.21

Cell-free translation of avian erythroblastosis virus RNA yields two specific and distinct proteins with molecular weights of 75,000 and 40,000. Virology (1980) 1.21