Published in Channels (Austin) on September 01, 2011
Molecular biophysics of Orai store-operated Ca2+ channels. Biophys J (2015) 1.09
Contribution and regulation of TRPC channels in store-operated Ca2+ entry. Curr Top Membr (2013) 1.03
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Activation of the endoplasmic reticulum calcium sensor STIM1 and store-operated calcium entry by rotavirus requires NSP4 viroporin activity. J Virol (2013) 0.90
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STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell (2009) 6.92
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STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. Nat Cell Biol (2006) 5.68
The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions. J Cell Biol (2006) 5.58
Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion. Proc Natl Acad Sci U S A (2007) 5.31
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Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells. Cell Regul (1989) 4.28
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Regulation of calcium influx by second messengers in rat mast cells. Nature (1988) 3.60
STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels. Nat Cell Biol (2007) 3.47
The cellular and molecular basis of store-operated calcium entry. Nat Cell Biol (2002) 3.40
Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell (2003) 3.11
Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation. J Biol Chem (2007) 3.05
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Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1. Biochem Biophys Res Commun (2006) 2.89
TRP channel proteins and signal transduction. Physiol Rev (2002) 2.68
Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components. J Biol Chem (2007) 2.63
Assembly of Trp1 in a signaling complex associated with caveolin-scaffolding lipid raft domains. J Biol Chem (2000) 2.43
STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction. Mol Cell (2008) 2.30
Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice. Proc Natl Acad Sci U S A (2007) 2.17
Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers. J Cell Biol (2002) 2.14
Emerging perspectives in store-operated Ca2+ entry: roles of Orai, Stim and TRP. Biochim Biophys Acta (2006) 2.00
Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels. J Biol Chem (2001) 1.99
Physiology, phylogeny, and functions of the TRP superfamily of cation channels. Sci STKE (2001) 1.95
Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells. Mol Pharmacol (2006) 1.92
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Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells. J Biol Chem (2005) 1.87
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Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes. J Exp Med (2002) 1.73
Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE). J Biol Chem (2008) 1.71
Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation (2006) 1.70
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A role for Orai in TRPC-mediated Ca2+ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca2+ entry. Proc Natl Acad Sci U S A (2009) 1.57
Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3. J Biol Chem (2005) 1.51
Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells. J Biol Chem (2007) 1.51
Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1. J Biol Chem (2003) 1.46
Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions. PLoS Biol (2011) 1.45
Interactions, functions, and independence of plasma membrane STIM1 and TRPC1 in vascular smooth muscle cells. Circ Res (2008) 1.45
RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. J Biol Chem (2003) 1.43
Cation channels of the transient receptor potential superfamily: their role in physiological and pathophysiological processes of smooth muscle cells. Pharmacol Ther (2006) 1.41
An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs. FEBS Lett (2009) 1.39
Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry. Biochem J (2009) 1.38
Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides. J Biol Chem (2009) 1.36
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Canonical transient receptor potential 1 plays a role in basic fibroblast growth factor (bFGF)/FGF receptor-1-induced Ca2+ entry and embryonic rat neural stem cell proliferation. J Neurosci (2005) 1.27
Function of caveolae in Ca2+ entry and Ca2+-dependent signal transduction. Traffic (2003) 1.25
Calcium signaling complexes in microdomains of polarized secretory cells. Cell Calcium (2006) 1.24
Homo- and heteromeric assembly of TRP channel subunits. Pflugers Arch (2005) 1.24
Emerging functions of 10 types of TRP cationic channel in vascular smooth muscle. Clin Exp Pharmacol Physiol (2005) 1.22
Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells. Traffic (2010) 1.20
Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1. Proc Natl Acad Sci U S A (2009) 1.20
Ca2+ signaling microdomains:platforms for the assembly and regulation of TRPC channels. Trends Pharmacol Sci (2005) 1.19
TRPC1 functions as a store-operated Ca2+ channel in intestinal epithelial cells and regulates early mucosal restitution after wounding. Am J Physiol Gastrointest Liver Physiol (2005) 1.18
Lipid rafts and regulation of the cytoskeleton during T cell activation. Philos Trans R Soc Lond B Biol Sci (2005) 1.11
Identification of mouse trp homologs and lipid rafts from spermatogenic cells and sperm. FEBS Lett (2001) 1.07
Relocalization of STIM1 for activation of store-operated Ca(2+) entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca(2+) store. J Biol Chem (2007) 1.06
Involvement of a calcium-dependent dephosphorylation of BAD associated with the localization of Trpc-1 within lipid rafts in 7-ketocholesterol-induced THP-1 cell apoptosis. Cell Death Differ (2004) 1.06
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Constitutive recycling of the store-operated Ca2+ channel Orai1 and its internalization during meiosis. J Cell Biol (2010) 1.03
Transient receptor potential protein subunit assembly and membrane distribution in human platelets. Thromb Haemost (2005) 1.02
Functional organization of TRPC-Ca2+ channels and regulation of calcium microdomains. Cell Calcium (2006) 1.02
Evidence that TRPC1 contributes to calcium-induced differentiation of human keratinocytes. Pflugers Arch (2005) 1.02
Organization and function of TRPC channelosomes. Pflugers Arch (2007) 1.01
The closing and opening of TRPC channels by Homer1 and STIM1. Acta Physiol (Oxf) (2011) 0.99
Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation. J Cell Sci (2009) 0.97
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Free cholesterol alters lipid raft structure and function regulating neutrophil Ca2+ entry and respiratory burst: correlations with calcium channel raft trafficking. J Immunol (2007) 0.96
Identification of two domains involved in the assembly of transient receptor potential canonical channels. J Biol Chem (2006) 0.90
Mechanism and functional significance of TRPC channel multimerization. Semin Cell Dev Biol (2006) 0.87
Regulation of KCa current by store-operated Ca2+ influx depends on internal Ca2+ release in HSG cells. Am J Physiol (1998) 0.86
TRPC channel interactions with calmodulin and IP3 receptors. Novartis Found Symp (2004) 0.85
Plasma membrane localization and function of TRPC1 is dependent on its interaction with beta-tubulin in retinal epithelium cells. Vis Neurosci (2005) 0.85
Local Ca2+ influx through CRAC channels activates temporally and spatially distinct cellular responses. Acta Physiol (Oxf) (2008) 0.85
Functional mapping of Ca2+ signaling complexes in plasma membrane microdomains of polarized cells. J Biol Chem (2004) 0.82
Assembly and gating of TRPC channels in signalling microdomains. Novartis Found Symp (2004) 0.81
Analysis of TRPC3-interacting proteins by tandem mass spectrometry. J Proteome Res (2008) 0.81
Regulation by scaffolding proteins of canonical transient receptor potential channels in striated muscle. J Muscle Res Cell Motil (2010) 0.80
Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components. J Biol Chem (2007) 2.63
Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice. Proc Natl Acad Sci U S A (2007) 2.17
Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels. J Biol Chem (2008) 1.74
Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE). J Biol Chem (2008) 1.71
STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjogren's syndrome. Proc Natl Acad Sci U S A (2012) 1.55
Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3. J Biol Chem (2005) 1.51
VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx. Mol Cell (2004) 1.49
Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1. J Biol Chem (2003) 1.46
Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions. PLoS Biol (2011) 1.45
TRPC1 is required for functional store-operated Ca2+ channels. Role of acidic amino acid residues in the S5-S6 region. J Biol Chem (2003) 1.37
Calmodulin regulates Ca(2+)-dependent feedback inhibition of store-operated Ca(2+) influx by interaction with a site in the C terminus of TrpC1. Mol Cell (2002) 1.32
Canonical transient receptor potential 1 plays a role in basic fibroblast growth factor (bFGF)/FGF receptor-1-induced Ca2+ entry and embryonic rat neural stem cell proliferation. J Neurosci (2005) 1.27
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. J Biol Chem (2004) 1.23
Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells. Traffic (2010) 1.20
Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1. Proc Natl Acad Sci U S A (2009) 1.20
Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients. PLoS One (2012) 1.18
Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier's disease. Mol Biol Cell (2006) 1.17
Conditional overexpression of TGF-beta1 disrupts mouse salivary gland development and function. Lab Invest (2010) 1.08
Relocalization of STIM1 for activation of store-operated Ca(2+) entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca(2+) store. J Biol Chem (2007) 1.06
Contribution of TRPC1 and Orai1 to Ca(2+) entry activated by store depletion. Adv Exp Med Biol (2011) 1.06
Depletion of intracellular Ca2+ stores stimulates the translocation of vanilloid transient receptor potential 4-c1 heteromeric channels to the plasma membrane. Arterioscler Thromb Vasc Biol (2010) 1.04
Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane. Proc Natl Acad Sci U S A (2012) 1.04
Contribution and regulation of TRPC channels in store-operated Ca2+ entry. Curr Top Membr (2013) 1.03
Heteromeric TRPV4-C1 channels contribute to store-operated Ca(2+) entry in vascular endothelial cells. Cell Calcium (2011) 1.00
Intracellular Ca(2+) release via the ER translocon activates store-operated calcium entry. Pflugers Arch (2006) 0.98
Ion channels and transporters in cancer. 6. Vascularizing the tumor: TRP channels as molecular targets. Am J Physiol Cell Physiol (2011) 0.95
Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression. J Biol Chem (2002) 0.94
TRPC3 controls agonist-stimulated intracellular Ca2+ release by mediating the interaction between inositol 1,4,5-trisphosphate receptor and RACK1. J Biol Chem (2008) 0.93
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands. Arthritis Rheum (2007) 0.90
Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1. J Cell Sci (2012) 0.90
Active secretion and protective effect of salivary nitrate against stress in human volunteers and rats. Free Radic Biol Med (2012) 0.87
Adenosine induces inositol 1,4,5-trisphosphate receptor-mediated mobilization of intracellular calcium stores in basal forebrain cholinergic neurons. J Neurosci (2002) 0.87
Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1. J Biol Chem (2004) 0.86
Physiological functions and regulation of TRPC channels. Handb Exp Pharmacol (2014) 0.82
Analysis of TRPC3-interacting proteins by tandem mass spectrometry. J Proteome Res (2008) 0.81
Extracellular Ca(2+) sensing in salivary ductal cells. J Biol Chem (2012) 0.81
Unraveling smooth muscle contraction: the TRP link. Gastroenterology (2009) 0.80
Diacylglycerols activate mitochondrial cationic channel(s) and release sequestered Ca(2+). J Bioenerg Biomembr (2005) 0.80