Published in Nature on July 17, 2013
Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell Stem Cell (2014) 2.24
The proper criteria for identification and sorting of very small embryonic-like stem cells, and some nomenclature issues. Stem Cells Dev (2014) 1.70
The H19 long noncoding RNA gives rise to microRNAs miR-675-3p and miR-675-5p to promote skeletal muscle differentiation and regeneration. Genes Dev (2014) 1.64
The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism. Cell Stem Cell (2015) 1.56
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Blood (2014) 1.34
Genomic imprinting in development, growth, behavior and stem cells. Development (2014) 1.23
The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells. Nucleic Acids Res (2014) 1.16
Very small embryonic-like stem cells (VSELs) represent a real challenge in stem cell biology: recent pros and cons in the midst of a lively debate. Leukemia (2013) 1.10
The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression. J Hematol Oncol (2015) 1.09
The H19 Long non-coding RNA in cancer initiation, progression and metastasis - a proposed unifying theory. Mol Cancer (2015) 1.08
Epigenetic modulators, modifiers and mediators in cancer aetiology and progression. Nat Rev Genet (2016) 1.07
miR675 upregulates long noncoding RNA H19 through activating EGR1 in human liver cancer. Oncotarget (2015) 0.94
H19 lncRNA alters stromal cell growth via IGF signaling in the endometrium of women with endometriosis. EMBO Mol Med (2015) 0.94
Epigenetics of myelodysplastic syndromes. Leukemia (2013) 0.92
H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase. Nat Commun (2015) 0.91
Hematopoietic stem/progenitor cells express several functional sex hormone receptors-novel evidence for a potential developmental link between hematopoiesis and primordial germ cells. Stem Cells Dev (2015) 0.91
Long non-coding RNAs control hematopoietic stem cell function. Cell Stem Cell (2015) 0.90
A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation. Genome Res (2015) 0.90
Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking. Nat Genet (2016) 0.89
Association of TGFβ signaling with the maintenance of a quiescent stem cell niche in human oral mucosa. Histochem Cell Biol (2016) 0.89
Long Non-Coding RNAs: The Key Players in Glioma Pathogenesis. Cancers (Basel) (2015) 0.87
CUDR promotes liver cancer stem cell growth through upregulating TERT and C-Myc. Oncotarget (2015) 0.87
Revisiting heritability accounting for shared environmental effects and maternal inheritance. Hum Genet (2014) 0.85
Positive effects of prolonged caloric restriction on the population of very small embryonic-like stem cells - hematopoietic and ovarian implications. J Ovarian Res (2014) 0.84
H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer. EBioMedicine (2016) 0.84
The Aging Epigenome. Mol Cell (2016) 0.84
First principles of Hamiltonian medicine. Philos Trans R Soc Lond B Biol Sci (2014) 0.83
Long Intergenic Non-Coding RNAs: Novel Drivers of Human Lymphocyte Differentiation. Front Immunol (2015) 0.83
Long noncoding RNAs during normal and malignant hematopoiesis. Int J Hematol (2014) 0.82
H19 promotes cholestatic liver fibrosis by preventing ZEB1-mediated inhibition of EpCAM. Hepatology (2017) 0.81
Overexpression of miR-483-5p/3p cooperate to inhibit mouse liver fibrosis by suppressing the TGF-β stimulated HSCs in transgenic mice. J Cell Mol Med (2014) 0.81
Epigenetic regulation of hematopoietic stem cell aging. Exp Cell Res (2014) 0.81
Delineating the effects of 5-fluorouracil and follicle-stimulating hormone on mouse bone marrow stem/progenitor cells. Stem Cell Res Ther (2016) 0.80
Mest but Not MiR-335 Affects Skeletal Muscle Growth and Regeneration. PLoS One (2015) 0.79
H19 derived microRNA-675 regulates cell proliferation and migration through CDK6 in glioma. Am J Transl Res (2015) 0.79
Regulation of mammary epithelial cell homeostasis by lncRNAs. Int J Biochem Cell Biol (2014) 0.79
Noncoding RNA control of cellular senescence. Wiley Interdiscip Rev RNA (2015) 0.79
The cell cycle- and insulin-signaling-inhibiting miRNA expression pattern of very small embryonic-like stem cells contributes to their quiescent state. Exp Biol Med (Maywood) (2015) 0.78
Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging. Aging Cell (2015) 0.78
Parental permissions: H19 and keeping the stem cell progeny under control. Cell Stem Cell (2013) 0.78
Transcriptome-wide profiling and posttranscriptional analysis of hematopoietic stem/progenitor cell differentiation toward myeloid commitment. Stem Cell Reports (2014) 0.77
Molecular mechanism of extrinsic factors affecting anti-aging of stem cells. World J Stem Cells (2015) 0.77
Imprinted genes in myeloid lineage commitment in normal and malignant hematopoiesis. Leukemia (2015) 0.76
H19/let-7/LIN28 reciprocal negative regulatory circuit promotes breast cancer stem cell maintenance. Cell Death Dis (2017) 0.75
Parentally imprinted genes regulate hematopoiesis-new evidence from the Dlk1-Gtl2 locus. Stem Cell Investig (2016) 0.75
Molecular microevolution and epigenetic patterns of the long non-coding gene H19 show its potential function in pig domestication and breed divergence. BMC Evol Biol (2016) 0.75
Single-nucleus RNA-seq of differentiating human myoblasts reveals the extent of fate heterogeneity. Nucleic Acids Res (2016) 0.75
Understanding of leukemic stem cells and their clinical implications. Mol Cancer (2017) 0.75
A G-quadruplex structure at the 5' end of the H19 coding region regulates H19 transcription. Sci Rep (2017) 0.75
Relative genomic stability of adipose tissue derived mesenchymal stem cells: analysis of ploidy, H19 long non-coding RNA and p53 activity. Stem Cell Res Ther (2014) 0.75
Mapping Whole-Transcriptome Splicing in Mouse Hematopoietic Stem Cells. Stem Cell Reports (2016) 0.75
H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction. Oncotarget (2016) 0.75
Prognostic value of abnormally expressed lncRNAs in ovarian carcinoma: a systematic review and meta-analysis. Oncotarget (2017) 0.75
Mammary gland stem cells and their application in breast cancer. Oncotarget (2016) 0.75
Linking Hematopoietic Differentiation to Co-Expressed Sets of Pluripotency-Associated and Imprinted Genes and to Regulatory microRNA-Transcription Factor Motifs. PLoS One (2017) 0.75
Long noncoding RNAs in hematopoiesis. F1000Res (2016) 0.75
Paternal Insulin-like Growth Factor 2 (Igf2) Regulates Stem Cell Activity During Adulthood. EBioMedicine (2016) 0.75
Trisomy 21 Alters DNA Methylation in Parent-of-Origin-Dependent and -Independent Manners. PLoS One (2016) 0.75
BALR-6 regulates cell growth and cell survival in B-lymphoblastic leukemia. Mol Cancer (2015) 0.75
Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice. J Biol Chem (2014) 0.75
Human Long Noncoding RNA Regulation of Stem Cell Potency and Differentiation. Stem Cells Int (2017) 0.75
lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling. Oncotarget (2017) 0.75
Prolonged Growth Hormone/Insulin/Insulin-like Growth Factor Nutrient Response Signaling Pathway as a Silent Killer of Stem Cells and a Culprit in Aging. Stem Cell Rev (2017) 0.75
RNA sequencing of db/db mice liver identifies lncRNA H19 as a key regulator of gluconeogenesis and hepatic glucose output. Sci Rep (2017) 0.75
The role of epigenetics in renal ageing. Nat Rev Nephrol (2017) 0.75
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12
Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol (2004) 101.91
Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89
TopHat: discovering splice junctions with RNA-Seq. Bioinformatics (2009) 81.13
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol (2010) 75.21
Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res (2003) 52.74
Identification of the haematopoietic stem cell niche and control of the niche size. Nature (2003) 18.17
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell (2007) 12.33
The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res (2007) 9.32
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions. Nat Genet (2006) 8.99
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature (2006) 7.35
Parental imprinting of the mouse insulin-like growth factor II gene. Cell (1991) 7.11
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature (2010) 7.05
Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment. Cell (2007) 3.82
Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth. Dev Cell (2006) 3.67
Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood (2002) 3.21
The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r. Nat Cell Biol (2012) 2.73
p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell (2011) 2.58
Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche. Cell (2012) 2.36
Adult mouse hematopoietic stem cells: purification and single-cell assays. Nat Protoc (2006) 2.29
Genomic imprinting: employing and avoiding epigenetic processes. Genes Dev (2009) 2.26
Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis. Nature (2011) 2.22
Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci. Cell Stem Cell (2011) 2.09
N-cadherin expression level distinguishes reserved versus primed states of hematopoietic stem cells. Cell Stem Cell (2008) 1.98
5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation. Exp Hematol (1990) 1.96
Expansion in vitro of adult murine hematopoietic stem cells with transplantable lympho-myeloid reconstituting ability. Proc Natl Acad Sci U S A (1997) 1.84
The importance of imprinting in the human placenta. PLoS Genet (2010) 1.74
Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes. Mamm Genome (2000) 1.71
Regulation of growth and metabolism by imprinted genes. Cytogenet Genome Res (2006) 1.63
Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion. Genes Dev (2011) 1.63
The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche. Nature (2012) 1.54
Igf1r as a therapeutic target in a mouse model of basal-like breast cancer. Proc Natl Acad Sci U S A (2009) 1.45
Smad4 is critical for self-renewal of hematopoietic stem cells. J Exp Med (2007) 1.25
Genomic imprinting mechanisms in embryonic and extraembryonic mouse tissues. Heredity (Edinb) (2010) 1.22
Developmental profile of H19 differentially methylated domain (DMD) deletion alleles reveals multiple roles of the DMD in regulating allelic expression and DNA methylation at the imprinted H19/Igf2 locus. Mol Cell Biol (2006) 1.19
A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity. Oncogene (2006) 1.12
Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells. PLoS One (2011) 1.06
Necdin restricts proliferation of hematopoietic stem cells during hematopoietic regeneration. Blood (2009) 1.04
Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63. Cell Signal (2003) 0.92
Insulin-like growth factor 2 enhances insulinogenic differentiation of human eyelid adipose stem cells via the insulin receptor. Cell Prolif (2011) 0.85
Identification of the haematopoietic stem cell niche and control of the niche size. Nature (2003) 18.17
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science (2010) 9.61
Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest (2007) 8.71
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet (2004) 7.37
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature (2006) 7.35
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell (2011) 6.80
Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell (2012) 4.67
Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization. J Biol Chem (2002) 4.52
Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. EMBO J (2008) 4.28
Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition. Cell (2010) 4.16
The stem cell niches in bone. J Clin Invest (2006) 4.11
PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat Genet (2007) 4.09
Detection of functional haematopoietic stem cell niche using real-time imaging. Nature (2008) 4.06
Essential role of beta-catenin in postnatal bone acquisition. J Biol Chem (2005) 3.88
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest (2007) 3.76
Current view: intestinal stem cells and signaling. Gastroenterology (2008) 3.46
Breast tumor copy number aberration phenotypes and genomic instability. BMC Cancer (2006) 3.34
Transcriptional accessibility for genes of multiple tissues and hematopoietic lineages is hierarchically controlled during early hematopoiesis. Blood (2002) 3.21
Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. Science (2004) 2.98
X-inactivation, imprinting, and long noncoding RNAs in health and disease. Cell (2013) 2.96
Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circ Res (2006) 2.95
MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. J Clin Invest (2010) 2.87
Genome sequence of foxtail millet (Setaria italica) provides insights into grass evolution and biofuel potential. Nat Biotechnol (2012) 2.82
Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation. J Am Chem Soc (2004) 2.79
Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF. Genome Biol (2008) 2.71
AP-3 directs the intracellular trafficking of HIV-1 Gag and plays a key role in particle assembly. Cell (2005) 2.68
Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration. Proc Natl Acad Sci U S A (2008) 2.65
Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes. Nature (2012) 2.57
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling. J Biol Chem (2008) 2.55
Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways. Immunity (2010) 2.39
Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange. Nat Struct Mol Biol (2012) 2.37
Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche. Cell (2012) 2.36
microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. Cancer Res (2009) 2.32
Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers. Cancer Discov (2013) 2.29
Genomic imprinting mechanisms in mammals. Mutat Res (2008) 2.28
Genomic imprinting: intricacies of epigenetic regulation in clusters. Annu Rev Cell Dev Biol (2003) 2.26
Gene-specific timing and epigenetic memory in oocyte imprinting. Hum Mol Genet (2004) 2.25
Selective loss of imprinting in the placenta following preimplantation development in culture. Development (2004) 2.23
Uncovering growth-suppressive MicroRNAs in lung cancer. Clin Cancer Res (2009) 2.19
Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome. Hum Mol Genet (2002) 2.16
Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol (2003) 2.12
Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation. Circ Res (2004) 2.10
Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells (2006) 2.09
DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages. Development (2006) 2.08
Generating daily high spatial land surface temperatures by combining ASTER and MODIS land surface temperature products for environmental process monitoring. Environ Sci Process Impacts (2015) 2.03
N-cadherin expression level distinguishes reserved versus primed states of hematopoietic stem cells. Cell Stem Cell (2008) 1.98
Structural insights on the Mycobacterium tuberculosis proteasomal ATPase Mpa. Structure (2009) 1.96
Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma. Blood (2011) 1.95
High conservation of transcription factor binding and evidence for combinatorial regulation across six Drosophila species. Nat Genet (2011) 1.94
BMP4 and Madh5 regulate the erythroid response to acute anemia. Blood (2004) 1.93
Genomic imprinting in mammals. Cold Spring Harb Perspect Biol (2014) 1.92
Genetic evidence points to an osteocalcin-independent influence of osteoblasts on energy metabolism. J Bone Miner Res (2011) 1.89
Nebulette mutations are associated with dilated cardiomyopathy and endocardial fibroelastosis. J Am Coll Cardiol (2010) 1.88
Disruption of imprinted gene methylation and expression in cloned preimplantation stage mouse embryos. Biol Reprod (2003) 1.88
BMP signaling and stem cell regulation. Dev Biol (2005) 1.77
Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice. J Orthop Res (2009) 1.76
Delayed correlation of mRNA and protein expression in rapamycin-treated cells and a role for Ggc1 in cellular sensitivity to rapamycin. Mol Cell Proteomics (2009) 1.76
Cryoelectron microscopy structure of purified gamma-secretase at 12 A resolution. J Mol Biol (2008) 1.75
Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger. Science (2012) 1.74
Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence. Cell Rep (2013) 1.74
Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling. FASEB J (2011) 1.74
Reprogramming of primordial germ cells begins before migration into the genital ridge, making these cells inadequate donors for reproductive cloning. Proc Natl Acad Sci U S A (2003) 1.73
Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4. Cell (2010) 1.73
Regulation of imprinting in clusters: noncoding RNAs versus insulators. Adv Genet (2008) 1.73
CTCF binding sites promote transcription initiation and prevent DNA methylation on the maternal allele at the imprinted H19/Igf2 locus. Hum Mol Genet (2006) 1.72
Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice. Aging Cell (2009) 1.72
Differential gene expression profiling of adult murine hematopoietic stem cells. Blood (2002) 1.69
Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone (2005) 1.68
Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development. Hum Mol Genet (2007) 1.67
Proteomic analysis identifies that 14-3-3zeta interacts with beta-catenin and facilitates its activation by Akt. Proc Natl Acad Sci U S A (2004) 1.66
Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay. Gastroenterology (2013) 1.64
Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion. Genes Dev (2011) 1.63
A nomenclature for intestinal in vitro cultures. Am J Physiol Gastrointest Liver Physiol (2012) 1.61
Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction. J Bone Miner Res (2002) 1.61
Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy. Mol Genet Metab (2007) 1.60
Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations. Nat Genet (2004) 1.60
Phosphatidylinositol monophosphate-binding interface in the oomycete RXLR effector AVR3a is required for its stability in host cells to modulate plant immunity. Proc Natl Acad Sci U S A (2011) 1.59
Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis. Gastroenterology (2010) 1.57