Published in Mol Cell Biol on July 26, 2011
Histone H2A variants in nucleosomes and chromatin: more or less stable? Nucleic Acids Res (2012) 1.33
H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization. Nucleic Acids Res (2012) 1.03
High-resolution network biology: connecting sequence with function. Nat Rev Genet (2013) 0.99
H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation. PLoS Genet (2013) 0.87
A conserved function for the H2A.Z C terminus. J Biol Chem (2012) 0.81
Unexplored potentials of epigenetic mechanisms of plants and animals-theoretical considerations. Genet Epigenet (2013) 0.79
Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects. PLoS Genet (2016) 0.78
Mutations in non-acid patch residues disrupt H2A.Z's association with chromatin through multiple mechanisms. PLoS One (2013) 0.76
SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression. Sci Rep (2017) 0.75
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast (1998) 48.29
Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature (1997) 44.55
Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell (2005) 10.41
ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science (2003) 10.04
In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. Methods Enzymol (1991) 8.90
Translational and rotational settings of H2A.Z nucleosomes across the Saccharomyces cerevisiae genome. Nature (2007) 8.68
Histone variant H2A.Z marks the 5' ends of both active and inactive genes in euchromatin. Cell (2005) 7.20
A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae. Microbiol Rev (1987) 7.00
Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin. Cell (2003) 6.83
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell (2003) 5.57
Rapid and reliable protein extraction from yeast. Yeast (2000) 5.48
Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss. Cell (2005) 5.36
A role for Saccharomyces cerevisiae histone H2A in DNA repair. Nature (2001) 5.28
A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin. PLoS Biol (2004) 5.02
Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning. PLoS Biol (2005) 4.48
Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants. Genes Dev (1997) 4.27
Crystal structure of a nucleosome core particle containing the variant histone H2A.Z. Nat Struct Biol (2000) 4.05
Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling. Proc Natl Acad Sci U S A (2005) 3.72
Histone H2A.Z regulats transcription and is partially redundant with nucleosome remodeling complexes. Cell (2000) 3.50
Functional organization of the S. cerevisiae phosphorylation network. Cell (2009) 3.15
Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation. Mol Cell (2009) 2.91
Assembly of variant histones into chromatin. Annu Rev Cell Dev Biol (2005) 2.77
Interactions of Isw2 chromatin remodeling complex with nucleosomal arrays: analyses using recombinant yeast histones and immobilized templates. Mol Cell Biol (2001) 2.63
H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding. Mol Cell (2004) 2.63
Swc2 is a widely conserved H2AZ-binding module essential for ATP-dependent histone exchange. Nat Struct Mol Biol (2005) 2.42
A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation. Nat Struct Mol Biol (2008) 2.22
Chromosome-wide Rad51 spreading and SUMO-H2A.Z-dependent chromosome fixation in response to a persistent DNA double-strand break. Mol Cell (2009) 2.15
H2A.Z is required for global chromatin integrity and for recruitment of RNA polymerase II under specific conditions. Mol Cell Biol (2001) 2.11
Nucleosome assembly protein 1 exchanges histone H2A-H2B dimers and assists nucleosome sliding. J Biol Chem (2004) 2.08
H2A.Z: view from the top. Structure (2008) 2.07
Telomeric heterochromatin boundaries require NuA4-dependent acetylation of histone variant H2A.Z in Saccharomyces cerevisiae. Genes Dev (2006) 2.01
Regions of variant histone His2AvD required for Drosophila development. Nature (1999) 1.98
Quantitative genetic analysis in Saccharomyces cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions. Methods (2006) 1.96
In and out: histone variant exchange in chromatin. Trends Biochem Sci (2005) 1.81
Stepwise histone replacement by SWR1 requires dual activation with histone H2A.Z and canonical nucleosome. Cell (2010) 1.71
Histone H2A.Z has a conserved function that is distinct from that of the major H2A sequence variants. Nucleic Acids Res (2000) 1.70
ATP-dependent nucleosome remodelling: factors and functions. J Cell Sci (2004) 1.68
Chz1, a nuclear chaperone for histone H2AZ. Mol Cell (2007) 1.64
Role of histone modifications in defining chromatin structure and function. Biol Chem (2008) 1.46
Quantitative genetic interaction mapping using the E-MAP approach. Methods Enzymol (2010) 1.35
Global analysis of functional surfaces of core histones with comprehensive point mutants. Genes Cells (2007) 1.25
Histone H2A subtypes associate interchangeably in vivo with histone H2B subtypes. Proc Natl Acad Sci U S A (1982) 1.25
Small epitope-linker modules for PCR-based C-terminal tagging in Saccharomyces cerevisiae. Yeast (2009) 1.20
Roles for H2A.Z and its acetylation in GAL1 transcription and gene induction, but not GAL1-transcriptional memory. PLoS Biol (2010) 1.20
The Tup1 corepressor directs Htz1 deposition at a specific promoter nucleosome marking the GAL1 gene for rapid activation. Mol Cell Biol (2007) 1.11
Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation. Proc Natl Acad Sci U S A (2009) 1.05
Histone H2A C-terminus regulates chromatin dynamics, remodeling, and histone H1 binding. PLoS Genet (2010) 1.04
HistoneHits: a database for histone mutations and their phenotypes. Genome Res (2009) 1.04
The docking domain of histone H2A is required for H1 binding and RSC-mediated nucleosome remodeling. Nucleic Acids Res (2010) 1.02
Diverse roles for histone H2A modifications in DNA damage response pathways in yeast. Genetics (2006) 0.97
Variant histone H2A.Z, but not the HMG proteins Nhp6a/b, is essential for the recruitment of Swi/Snf, Mediator, and SAGA to the yeast GAL1 UAS(G). Biochem Biophys Res Commun (2008) 0.94
Histone H2A.Z acid patch residues required for deposition and function. Mol Genet Genomics (2011) 0.88
Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library. Genes Cells (2011) 0.81
A Bayesian networks approach for predicting protein-protein interactions from genomic data. Science (2003) 12.07
Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell (2005) 10.41
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature (2007) 9.25
Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Mol Cell Proteomics (2007) 7.93
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell (2005) 7.21
Exploration of essential gene functions via titratable promoter alleles. Cell (2004) 5.21
RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Mol Cell Biol (2002) 5.04
The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II. Nature (2004) 4.65
Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol Cell (2003) 4.49
A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biol (2006) 4.49
Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Science (2008) 4.36
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature (2005) 4.33
Host cell factors in HIV replication: meta-analysis of genome-wide studies. PLoS Pathog (2009) 4.24
INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell (2004) 4.20
Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling. Proc Natl Acad Sci U S A (2009) 4.11
Rewiring of genetic networks in response to DNA damage. Science (2010) 4.03
A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods (2008) 3.79
Differential network biology. Mol Syst Biol (2012) 3.74
Global landscape of HIV-human protein complexes. Nature (2011) 3.70
Phenotypic landscape of a bacterial cell. Cell (2010) 3.50
Transitions in RNA polymerase II elongation complexes at the 3' ends of genes. EMBO J (2004) 3.50
Learning a prior on regulatory potential from eQTL data. PLoS Genet (2009) 3.31
High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe. Nat Methods (2007) 3.24
Histone H2B ubiquitylation is associated with elongating RNA polymerase II. Mol Cell Biol (2005) 3.20
Factors underlying variable DNA methylation in a human community cohort. Proc Natl Acad Sci U S A (2012) 3.20
High-throughput, quantitative analyses of genetic interactions in E. coli. Nat Methods (2008) 3.17
Functional organization of the S. cerevisiae phosphorylation network. Cell (2009) 3.15
A panoramic view of yeast noncoding RNA processing. Cell (2003) 3.11
Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (2008) 3.09
A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell (2008) 2.96
A gene ontology inferred from molecular networks. Nat Biotechnol (2013) 2.95
Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array. Epigenetics Chromatin (2013) 2.93
SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors. Nat Cell Biol (2011) 2.92
Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation. Mol Cell (2009) 2.91
HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription. Mol Cell (2010) 2.91
Systematic functional prioritization of protein posttranslational modifications. Cell (2012) 2.78
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection. Nature (2011) 2.71
A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell (2006) 2.71
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science (2013) 2.68
Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. PLoS Biol (2009) 2.67
HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Traffic (2010) 2.47
Functional maps of protein complexes from quantitative genetic interaction data. PLoS Comput Biol (2008) 2.46
The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4. Genes Dev (2006) 2.42
BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex. Curr Biol (2005) 2.32
H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. Mol Cell (2007) 2.32
Functional overlap and regulatory links shape genetic interactions between signaling pathways. Cell (2010) 2.29
Different measures of "genome-wide" DNA methylation exhibit unique properties in placental and somatic tissues. Epigenetics (2012) 2.17
Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence. Child Dev (2011) 2.07
Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109. Mol Cell Biol (2008) 2.05
The specificity and topology of chromatin interaction pathways in yeast. Mol Cell (2011) 2.04
Population-specificity of human DNA methylation. Genome Biol (2012) 2.04
Symmetrized characterization of noisy quantum processes. Science (2007) 1.89
Hierarchical modularity and the evolution of genetic interactomes across species. Mol Cell (2012) 1.88
From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II. Cell (2013) 1.87
The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion. Mol Cell Biol (2004) 1.87
H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Mol Cell Biol (2005) 1.82
GammaH2AX and its role in DNA double-strand break repair. Biochem Cell Biol (2006) 1.81
Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis. Proc Natl Acad Sci U S A (2013) 1.81
Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Mol Syst Biol (2007) 1.79
Dissection of DNA damage responses using multiconditional genetic interaction maps. Mol Cell (2012) 1.78
Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation. Cell Stem Cell (2010) 1.74
R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants. Genes Dev (2012) 1.69
Quantitative genetic-interaction mapping in mammalian cells. Nat Methods (2013) 1.68
Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss. Mol Syst Biol (2007) 1.67
Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Mol Biol Cell (2005) 1.66
Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol (2008) 1.65
Quantitative genetic interactions reveal biological modularity. Cell (2010) 1.64
Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation. Hum Genet (2011) 1.60
Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods (2013) 1.60
Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Mol Cell (2005) 1.51
YEATS domain proteins: a diverse family with many links to chromatin modification and transcription. Biochem Cell Biol (2009) 1.44
A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Nat Struct Mol Biol (2010) 1.44
A complex-based reconstruction of the Saccharomyces cerevisiae interactome. Mol Cell Proteomics (2009) 1.42
Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell (2007) 1.41
A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast. Mol Cell (2008) 1.36
Quantitative genetic interaction mapping using the E-MAP approach. Methods Enzymol (2010) 1.35
Dot1 and histone H3K79 methylation in natural telomeric and HM silencing. Mol Cell (2011) 1.32
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nat Genet (2012) 1.31
Evolution and functional cross-talk of protein post-translational modifications. Mol Syst Biol (2013) 1.30
Splitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123. Genes Dev (2011) 1.30
CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proc Natl Acad Sci U S A (2007) 1.30
Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol (2010) 1.30
First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G. ACS Chem Biol (2012) 1.28
Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production. Mol Cell Proteomics (2011) 1.28
An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe. Nat Struct Mol Biol (2009) 1.27
Purification and characterization of HIV-human protein complexes. Methods (2010) 1.26
Eisosome proteins assemble into a membrane scaffold. J Cell Biol (2011) 1.24
Genome-wide association data reveal a global map of genetic interactions among protein complexes. PLoS Genet (2009) 1.23
CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. Mol Cell (2013) 1.23
Roles for H2A.Z and its acetylation in GAL1 transcription and gene induction, but not GAL1-transcriptional memory. PLoS Biol (2010) 1.20
The RNA polymerase II kinase Ctk1 regulates positioning of a 5' histone methylation boundary along genes. Mol Cell Biol (2006) 1.19
NuA4 and SWR1-C: two chromatin-modifying complexes with overlapping functions and components. Biochem Cell Biol (2009) 1.18
Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium. Am J Respir Crit Care Med (2010) 1.14
Human placental-specific epipolymorphism and its association with adverse pregnancy outcomes. PLoS One (2009) 1.14
The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory. Nat Neurosci (2011) 1.13
Extensive epigenetic reprogramming in human somatic tissues between fetus and adult. Epigenetics Chromatin (2011) 1.13
Systems-level analyses identify extensive coupling among gene expression machines. Mol Syst Biol (2006) 1.12
Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Mol Cell (2011) 1.11
HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold. Proc Natl Acad Sci U S A (2012) 1.08