Cormac T Taylor

Author PubWeight™ 72.81‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity. Proc Natl Acad Sci U S A 2006 4.08
2 Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha. Science 2003 3.91
3 Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation 2005 2.99
4 The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis. Gastroenterology 2007 2.87
5 Hypoxia-responsive transcription factors. Pflugers Arch 2005 2.64
6 Hypoxia: an alarm signal during intestinal inflammation. Nat Rev Gastroenterol Hepatol 2010 2.18
7 MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia. Mol Cell Biol 2011 1.81
8 A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury. Proc Natl Acad Sci U S A 2009 1.78
9 Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function. Gastroenterology 2010 1.64
10 Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury. FASEB J 2006 1.61
11 Regulation of oxygen distribution in tissues by endothelial nitric oxide. Circ Res 2009 1.61
12 Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia. Proc Natl Acad Sci U S A 2003 1.52
13 Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome. Am J Respir Crit Care Med 2006 1.50
14 Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. J Clin Invest 2011 1.44
15 PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells. Proc Natl Acad Sci U S A 2009 1.38
16 The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia. J Biol Chem 2003 1.33
17 Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production. J Biol Chem 2010 1.33
18 Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog. Kidney Int 2003 1.21
19 An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia. J Immunol 2010 1.20
20 NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells. J Immunol 2010 1.12
21 Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways. Proc Natl Acad Sci U S A 2013 1.12
22 Gremlin plays a key role in the pathogenesis of pulmonary hypertension. Circulation 2012 1.11
23 Carbon dioxide-sensing in organisms and its implications for human disease. Cell Mol Life Sci 2013 1.10
24 15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure. J Am Soc Nephrol 2002 1.08
25 Targeting the HIF pathway in inflammation and immunity. Curr Opin Pharmacol 2013 1.07
26 c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia. Cancer Res 2004 1.05
27 A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network. J Cell Sci 2013 1.03
28 Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung. Am J Respir Crit Care Med 2008 0.97
29 A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation. Biochem Biophys Res Commun 2007 0.97
30 Hypoxia induces epithelial amphiregulin gene expression in a CREB-dependent manner. Am J Physiol Cell Physiol 2005 0.96
31 Hypoxia increases antibiotic resistance in Pseudomonas aeruginosa through altering the composition of multidrug efflux pumps. Antimicrob Agents Chemother 2012 0.96
32 Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia. J Biol Chem 2010 0.95
33 Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases. Arthritis Res Ther 2009 0.95
34 Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor. J Immunol 2005 0.94
35 Hypoxia activates NF-kappaB-dependent gene expression through the canonical signaling pathway. Antioxid Redox Signal 2009 0.94
36 NFκB and HIF display synergistic behaviour during hypoxic inflammation. Cell Mol Life Sci 2011 0.94
37 Hypoxia, innate immunity and infection in the lung. Respir Physiol Neurobiol 2010 0.93
38 The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells. Shock 2011 0.93
39 Hydroxylases as therapeutic targets in inflammatory bowel disease. Lab Invest 2013 0.92
40 Hypercapnia induces cleavage and nuclear localization of RelB protein, giving insight into CO2 sensing and signaling. J Biol Chem 2012 0.92
41 SUMO, hypoxia and the regulation of metabolism. Biochem Soc Trans 2008 0.89
42 Alterations in oxidative gene expression in equine skeletal muscle following exercise and training. Physiol Genomics 2009 0.88
43 Effects of heat shock and hypoxia on neonatal neutrophil lipopolysaccharide responses: altered apoptosis, Toll-like receptor-4 and CD11b expression compared with adults. Biol Neonate 2006 0.87
44 Hydroxylase-dependent regulation of the NF-κB pathway. Biol Chem 2013 0.86
45 Hypoxia-dependent regulation of inflammatory pathways in immune cells. J Clin Invest 2016 0.86
46 Hypoxic regulation of NF-kappaB signaling. Methods Enzymol 2007 0.85
47 Regulation of protein phosphatase 1gamma activity in hypoxia through increased interaction with NIPP1: implications for cellular metabolism. J Cell Physiol 2006 0.85
48 Hypoxia modulates infection of epithelial cells by Pseudomonas aeruginosa. PLoS One 2013 0.83
49 The impact of hypoxia on cell death pathways. Biochem Soc Trans 2013 0.83
50 Lower expression of Nrf2 mRNA in older donor livers: a possible contributor to increased ischemia-reperfusion injury? Transplantation 2007 0.82
51 Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique. Integr Biol (Camb) 2010 0.80
52 Cholera toxin potentiates influences of IFN-gamma through activation of NF-kappaB and release of tumor necrosis factor-alpha. J Interferon Cytokine Res 2005 0.80
53 Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange. Biochim Biophys Acta 2010 0.79
54 Hydroxylase inhibition attenuates colonic epithelial secretory function and ameliorates experimental diarrhea. FASEB J 2010 0.79
55 Mitochondria, oxygen sensing, and the regulation of HIF-2alpha. Focus on "Induction of HIF-2alpha is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line". Am J Physiol Cell Physiol 2008 0.79
56 Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion. Mol Cell Biochem 2012 0.78
57 Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue. Adv Exp Med Biol 2002 0.77
58 A dynamic model of the hypoxia-inducible factor 1a (HIF-1a) network. J Cell Sci 2015 0.77
59 Enhanced sensitivity of protein kinase B/Akt to insulin in hypoxia is independent of HIF1alpha and promotes cell viability. Eur J Cell Biol 2007 0.75
60 Resistance to caspase-dependent, hypoxia-induced apoptosis is not hypoxia-inducible factor-1 alpha mediated in prostate carcinoma cells. Cancer 2005 0.75
61 Identification of cyclic AMP response element-binding protein-dependent transcriptional responses in hypoxia by microarray analysis. Methods Enzymol 2004 0.75