Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity.
|
Proc Natl Acad Sci U S A
|
2006
|
4.08
|
2
|
Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha.
|
Science
|
2003
|
3.91
|
3
|
Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome.
|
Circulation
|
2005
|
2.99
|
4
|
The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis.
|
Gastroenterology
|
2007
|
2.87
|
5
|
Hypoxia-responsive transcription factors.
|
Pflugers Arch
|
2005
|
2.64
|
6
|
Hypoxia: an alarm signal during intestinal inflammation.
|
Nat Rev Gastroenterol Hepatol
|
2010
|
2.18
|
7
|
MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia.
|
Mol Cell Biol
|
2011
|
1.81
|
8
|
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury.
|
Proc Natl Acad Sci U S A
|
2009
|
1.78
|
9
|
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
|
Gastroenterology
|
2010
|
1.64
|
10
|
Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury.
|
FASEB J
|
2006
|
1.61
|
11
|
Regulation of oxygen distribution in tissues by endothelial nitric oxide.
|
Circ Res
|
2009
|
1.61
|
12
|
Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia.
|
Proc Natl Acad Sci U S A
|
2003
|
1.52
|
13
|
Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome.
|
Am J Respir Crit Care Med
|
2006
|
1.50
|
14
|
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.
|
J Clin Invest
|
2011
|
1.44
|
15
|
PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells.
|
Proc Natl Acad Sci U S A
|
2009
|
1.38
|
16
|
The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia.
|
J Biol Chem
|
2003
|
1.33
|
17
|
Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production.
|
J Biol Chem
|
2010
|
1.33
|
18
|
Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog.
|
Kidney Int
|
2003
|
1.21
|
19
|
An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia.
|
J Immunol
|
2010
|
1.20
|
20
|
NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells.
|
J Immunol
|
2010
|
1.12
|
21
|
Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
|
Proc Natl Acad Sci U S A
|
2013
|
1.12
|
22
|
Gremlin plays a key role in the pathogenesis of pulmonary hypertension.
|
Circulation
|
2012
|
1.11
|
23
|
Carbon dioxide-sensing in organisms and its implications for human disease.
|
Cell Mol Life Sci
|
2013
|
1.10
|
24
|
15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure.
|
J Am Soc Nephrol
|
2002
|
1.08
|
25
|
Targeting the HIF pathway in inflammation and immunity.
|
Curr Opin Pharmacol
|
2013
|
1.07
|
26
|
c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia.
|
Cancer Res
|
2004
|
1.05
|
27
|
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
|
J Cell Sci
|
2013
|
1.03
|
28
|
Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung.
|
Am J Respir Crit Care Med
|
2008
|
0.97
|
29
|
A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation.
|
Biochem Biophys Res Commun
|
2007
|
0.97
|
30
|
Hypoxia induces epithelial amphiregulin gene expression in a CREB-dependent manner.
|
Am J Physiol Cell Physiol
|
2005
|
0.96
|
31
|
Hypoxia increases antibiotic resistance in Pseudomonas aeruginosa through altering the composition of multidrug efflux pumps.
|
Antimicrob Agents Chemother
|
2012
|
0.96
|
32
|
Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia.
|
J Biol Chem
|
2010
|
0.95
|
33
|
Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases.
|
Arthritis Res Ther
|
2009
|
0.95
|
34
|
Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor.
|
J Immunol
|
2005
|
0.94
|
35
|
Hypoxia activates NF-kappaB-dependent gene expression through the canonical signaling pathway.
|
Antioxid Redox Signal
|
2009
|
0.94
|
36
|
NFκB and HIF display synergistic behaviour during hypoxic inflammation.
|
Cell Mol Life Sci
|
2011
|
0.94
|
37
|
Hypoxia, innate immunity and infection in the lung.
|
Respir Physiol Neurobiol
|
2010
|
0.93
|
38
|
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells.
|
Shock
|
2011
|
0.93
|
39
|
Hydroxylases as therapeutic targets in inflammatory bowel disease.
|
Lab Invest
|
2013
|
0.92
|
40
|
Hypercapnia induces cleavage and nuclear localization of RelB protein, giving insight into CO2 sensing and signaling.
|
J Biol Chem
|
2012
|
0.92
|
41
|
SUMO, hypoxia and the regulation of metabolism.
|
Biochem Soc Trans
|
2008
|
0.89
|
42
|
Alterations in oxidative gene expression in equine skeletal muscle following exercise and training.
|
Physiol Genomics
|
2009
|
0.88
|
43
|
Effects of heat shock and hypoxia on neonatal neutrophil lipopolysaccharide responses: altered apoptosis, Toll-like receptor-4 and CD11b expression compared with adults.
|
Biol Neonate
|
2006
|
0.87
|
44
|
Hydroxylase-dependent regulation of the NF-κB pathway.
|
Biol Chem
|
2013
|
0.86
|
45
|
Hypoxia-dependent regulation of inflammatory pathways in immune cells.
|
J Clin Invest
|
2016
|
0.86
|
46
|
Hypoxic regulation of NF-kappaB signaling.
|
Methods Enzymol
|
2007
|
0.85
|
47
|
Regulation of protein phosphatase 1gamma activity in hypoxia through increased interaction with NIPP1: implications for cellular metabolism.
|
J Cell Physiol
|
2006
|
0.85
|
48
|
Hypoxia modulates infection of epithelial cells by Pseudomonas aeruginosa.
|
PLoS One
|
2013
|
0.83
|
49
|
The impact of hypoxia on cell death pathways.
|
Biochem Soc Trans
|
2013
|
0.83
|
50
|
Lower expression of Nrf2 mRNA in older donor livers: a possible contributor to increased ischemia-reperfusion injury?
|
Transplantation
|
2007
|
0.82
|
51
|
Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique.
|
Integr Biol (Camb)
|
2010
|
0.80
|
52
|
Cholera toxin potentiates influences of IFN-gamma through activation of NF-kappaB and release of tumor necrosis factor-alpha.
|
J Interferon Cytokine Res
|
2005
|
0.80
|
53
|
Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange.
|
Biochim Biophys Acta
|
2010
|
0.79
|
54
|
Hydroxylase inhibition attenuates colonic epithelial secretory function and ameliorates experimental diarrhea.
|
FASEB J
|
2010
|
0.79
|
55
|
Mitochondria, oxygen sensing, and the regulation of HIF-2alpha. Focus on "Induction of HIF-2alpha is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line".
|
Am J Physiol Cell Physiol
|
2008
|
0.79
|
56
|
Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion.
|
Mol Cell Biochem
|
2012
|
0.78
|
57
|
Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue.
|
Adv Exp Med Biol
|
2002
|
0.77
|
58
|
A dynamic model of the hypoxia-inducible factor 1a (HIF-1a) network.
|
J Cell Sci
|
2015
|
0.77
|
59
|
Enhanced sensitivity of protein kinase B/Akt to insulin in hypoxia is independent of HIF1alpha and promotes cell viability.
|
Eur J Cell Biol
|
2007
|
0.75
|
60
|
Resistance to caspase-dependent, hypoxia-induced apoptosis is not hypoxia-inducible factor-1 alpha mediated in prostate carcinoma cells.
|
Cancer
|
2005
|
0.75
|
61
|
Identification of cyclic AMP response element-binding protein-dependent transcriptional responses in hypoxia by microarray analysis.
|
Methods Enzymol
|
2004
|
0.75
|