Published in FEBS Lett on August 18, 2011
Dimethyl fumarate modulates antioxidant and lipid metabolism in oligodendrocytes. Redox Biol (2015) 0.78
TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin Repair. PLoS One (2016) 0.75
Multiple sclerosis. N Engl J Med (2000) 12.69
Axonal transection in the lesions of multiple sclerosis. N Engl J Med (1998) 12.21
Neurotrophins: roles in neuronal development and function. Annu Rev Neurosci (2001) 11.40
Transcriptional control by the TGF-beta/Smad signaling system. EMBO J (2000) 8.49
Remyelination in the CNS: from biology to therapy. Nat Rev Neurosci (2008) 6.16
Axonal neuregulin-1 regulates myelin sheath thickness. Science (2004) 6.09
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell (1989) 5.72
Neuregulins: functions, forms, and signaling strategies. Exp Cell Res (2003) 4.62
Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130. Science (1994) 4.24
Neuregulin-1 type III determines the ensheathment fate of axons. Neuron (2005) 4.19
Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron (2000) 4.17
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components. Science (1994) 4.07
Differential Notch signalling distinguishes neural stem cells from intermediate progenitors. Nature (2007) 4.02
Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med (2002) 3.68
Purification of a new neurotrophic factor from mammalian brain. EMBO J (1982) 3.68
Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal. Nature (2010) 3.54
Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell (1994) 3.52
Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature (1992) 3.39
Notch receptor activation inhibits oligodendrocyte differentiation. Neuron (1998) 3.30
NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes. Neuron (2004) 3.24
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci (2009) 3.18
IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase. Science (1993) 3.13
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Cell (2006) 3.12
Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat Med (2002) 3.04
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev (2009) 2.96
LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. Science (1993) 2.93
Endogenous progenitors remyelinate demyelinated axons in the adult CNS. Neuron (1997) 2.93
Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain (2008) 2.83
Axonal regulation of myelination by neuregulin 1. Curr Opin Neurobiol (2006) 2.78
The many facets of Notch ligands. Oncogene (2008) 2.57
Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination. Eur J Neurosci (1999) 2.56
Multiple extracellular signals are required for long-term oligodendrocyte survival. Development (1993) 2.55
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med (2005) 2.46
A role for the roof plate and its resident TGFbeta-related proteins in neuronal patterning in the dorsal spinal cord. Cell (1997) 2.40
Oligodendrocyte wars. Nat Rev Neurosci (2006) 2.39
The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron (2007) 2.38
Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells. J Neurosci (1998) 2.36
Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol (2005) 2.34
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system. Neuron (2008) 2.27
Disruption of the CNTF gene results in motor neuron degeneration. Nature (1993) 2.22
Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons. Neuron (1995) 2.19
Diversity and pattern in the developing spinal cord. Science (1996) 2.18
Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. J Neurosci (1998) 2.17
Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Neuron (2005) 2.12
F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell (2003) 2.05
Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain. Neuron (2005) 2.03
IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes. J Cell Biol (2004) 2.02
Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J Neurosci (2002) 2.00
Bone morphogenetic protein signalling and vertebrate nervous system development. Nat Rev Neurosci (2005) 1.97
Signals to promote myelin formation and repair. Nat Rev Neurol (2010) 1.95
Acquiring signalling specificity from the cytokine receptor gp130. Trends Genet (2004) 1.94
Retinoid X receptors: common heterodimerization partners with distinct functions. Trends Endocrinol Metab (2010) 1.93
Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. Neuron (1993) 1.93
CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation. Nat Med (2002) 1.91
Remyelination in multiple sclerosis. Ann Neurol (1979) 1.89
GGF/neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors. Neuron (1996) 1.84
Retinoid X receptor gamma signaling accelerates CNS remyelination. Nat Neurosci (2010) 1.84
A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool. J Cell Biol (2000) 1.76
Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells. J Neurosci (2005) 1.75
Activation of the subventricular zone in multiple sclerosis: evidence for early glial progenitors. Proc Natl Acad Sci U S A (2007) 1.71
Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO J (2005) 1.68
Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol (2002) 1.65
Bone morphogenetic proteins in the nervous system. Trends Neurosci (1997) 1.62
Differentiation of proliferated NG2-positive glial progenitor cells in a remyelinating lesion. J Neurosci Res (2002) 1.61
A crucial role for neurotrophin-3 in oligodendrocyte development. Nature (1994) 1.60
LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival. Nat Med (2002) 1.57
Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons. Proc Natl Acad Sci U S A (1994) 1.54
Ciliary neurotrophic factor and leukemia inhibitory factor promote the generation, maturation and survival of oligodendrocytes in vitro. Development (1994) 1.54
Type III neuregulin-1 promotes oligodendrocyte myelination. Glia (2008) 1.52
Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis. Brain (2010) 1.52
Central remyelination restores secure conduction. Nature (1979) 1.50
In vivo proliferation of oligodendrocyte progenitors expressing PDGFalphaR during early remyelination. J Neurobiol (1998) 1.48
Transplantation of ciliary neurotrophic factor-expressing adult oligodendrocyte precursor cells promotes remyelination and functional recovery after spinal cord injury. J Neurosci (2010) 1.46
Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proc Natl Acad Sci U S A (2009) 1.46
Ciliary neurotrophic factor (CNTF) enhances myelin formation: a novel role for CNTF and CNTF-related molecules. J Neurosci (2002) 1.45
Histone modifications and nuclear architecture: a review. J Histochem Cytochem (2008) 1.42
Wnt signaling is sufficient to perturb oligodendrocyte maturation. Mol Cell Neurosci (2009) 1.37
Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation. J Neurosci (2006) 1.35
Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor. Mol Cell Neurosci (1997) 1.33
A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group. Neurology (1996) 1.33
Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain (2004) 1.33
Interaction between NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells is required for optimal response to PDGF. J Neurosci Res (1996) 1.32
Multiple novel transcription initiation sites for NRG1. Gene (2004) 1.31
In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice. J Neurosci (1995) 1.30
Pre-oligodendrocytes from adult human CNS. J Neurosci (1992) 1.29
A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci (2009) 1.27
Insulin-like growth factor I/somatomedin C: a potent inducer of oligodendrocyte development. Proc Natl Acad Sci U S A (1986) 1.27
Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons. J Neurosci (2001) 1.24
Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease. Nature (1997) 1.21
Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3. J Cell Biol (1997) 1.20
Insulin-like growth factor I treatment reduces demyelination and up-regulates gene expression of myelin-related proteins in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (1995) 1.20
Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis. J Clin Invest (2008) 1.19
Bone morphogenetic proteins negatively control oligodendrocyte precursor specification in the chick spinal cord. Development (2002) 1.19
Oligodendrocyte maturation is inhibited by bone morphogenetic protein. Mol Cell Neurosci (2004) 1.19
A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group. Ann Neurol (1996) 1.16
Bone morphogenetic proteins promote gliosis in demyelinating spinal cord lesions. Ann Neurol (2007) 1.13
Regionally specific effects of BDNF on oligodendrocytes. Dev Neurosci (2003) 1.13
Grafts of brain-derived neurotrophic factor and neurotrophin 3-transduced primate Schwann cells lead to functional recovery of the demyelinated mouse spinal cord. J Neurosci (2005) 1.09
A pilot study of recombinant insulin-like growth factor-1 in seven multiple sderosis patients. Mult Scler (2002) 1.09
Evidence that axon-derived neuregulin promotes oligodendrocyte survival in the developing rat optic nerve. Neuron (2000) 1.09
VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown. Proc Natl Acad Sci U S A (2009) 2.25
Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease. J Clin Invest (2012) 1.90
IL-1beta regulates blood-brain barrier permeability via reactivation of the hypoxia-angiogenesis program. J Immunol (2006) 1.57
Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination. Acta Neuropathol (2012) 1.53
Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proc Natl Acad Sci U S A (2009) 1.46
Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis. J Neurosci (2004) 1.40
Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation. J Neurosci (2006) 1.35
Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy. J Infect Dis (2008) 1.34
CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis. Brain (2005) 1.30
Adolescent C57BL/6J (but not DBA/2J) mice consume greater amounts of limited-access ethanol compared to adults and display continued elevated ethanol intake into adulthood. Alcohol Clin Exp Res (2010) 1.17
Myosin II has distinct functions in PNS and CNS myelin sheath formation. J Cell Biol (2008) 1.14
The cytokine IL-1beta activates IFN response factor 3 in human fetal astrocytes in culture. J Immunol (2005) 1.05
Panitumumab: human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer. Clin Ther (2008) 1.05
IL-11 regulates autoimmune demyelination. J Immunol (2009) 0.95
Myosin II is a negative regulator of oligodendrocyte morphological differentiation. J Neurosci Res (2012) 0.93
MLCK regulates Schwann cell cytoskeletal organization, differentiation and myelination. J Cell Sci (2011) 0.87
Proapoptotic and antiapoptotic actions of Stat1 versus Stat3 underlie neuroprotective and immunoregulatory functions of IL-11. J Immunol (2011) 0.86
Thrombin activatable fibrinolysis inhibitor (TAFI) levels in patients with coronary artery disease investigated by angiography. Thromb Haemost (2002) 0.85
Antiepileptic hypersensitivity syndrome: clinicians beware and be aware. Curr Allergy Asthma Rep (2002) 0.85
Accelerated repair of demyelinated CNS lesions in the absence of non-muscle myosin IIB. Glia (2014) 0.82
Revisiting Notch in remyelination of multiple sclerosis lesions. J Clin Invest (2009) 0.81
Thalidomide use in pediatric patients. Ann Pharmacother (2002) 0.80
Targeting oligodendrocyte protection and remyelination in multiple sclerosis. Mt Sinai J Med (2011) 0.78
Facebook as a site for negative age stereotypes. Gerontologist (2013) 0.77
Signal-amplifying conjugated polymer-DNA hybrid chips. Angew Chem Int Ed Engl (2007) 0.77
On the occurrence of hypomyelination in a transgenic mouse model: a consequence of the myelin basic protein promoter? J Neuropathol Exp Neurol (2011) 0.75