Published in Neurosci Res on August 12, 2011
DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth. Int J Epidemiol (2012) 1.30
Rapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cells. Sci Signal (2013) 0.90
Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase. Mol Cell Biol (2014) 0.89
Hippocampal commissure defects in crosses of four inbred mouse strains with absent corpus callosum. Genes Brain Behav (2012) 0.83
Axon guidance mechanisms for establishment of callosal connections. Neural Plast (2013) 0.78
Deletion of Rapgef6, a candidate schizophrenia susceptibility gene, disrupts amygdala function in mice. Transl Psychiatry (2015) 0.76
Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders. PLoS Genet (2017) 0.75
NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain. eNeuro (2017) 0.75
In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction. Proc Natl Acad Sci U S A (2013) 3.10
Multiple roles of phosphoinositide-specific phospholipase C isozymes. BMB Rep (2008) 2.90
Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron (2005) 2.66
Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP. Proc Natl Acad Sci U S A (2007) 2.59
Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev Cell (2003) 2.54
Origin of climbing fiber neurons and their developmental dependence on Ptf1a. J Neurosci (2007) 1.84
Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development. Cancer Res (2004) 1.84
Phospholipase Cepsilon promotes intestinal tumorigenesis of Apc(Min/+) mice through augmentation of inflammation and angiogenesis. Carcinogenesis (2009) 1.62
A human case of an azygos lobe: determining an anatomical basis for its therapeutic postural drainage. Clin Anat (2008) 1.61
Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma. FASEB J (2010) 1.35
The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytes. Mol Biol Cell (2007) 1.30
Fukutin is required for maintenance of muscle integrity, cortical histiogenesis and normal eye development. Hum Mol Genet (2003) 1.27
Single- and multiple-molecule dynamics of the signaling from H-Ras to cRaf-1 visualized on the plasma membrane of living cells. Chemphyschem (2003) 1.26
Structural basis for conformational dynamics of GTP-bound Ras protein. J Biol Chem (2010) 1.26
Crucial role of phospholipase C epsilon in skin inflammation induced by tumor-promoting phorbol ester. Cancer Res (2008) 1.25
Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase C epsilon. Oncogene (2002) 1.24
Usage of tautomycetin, a novel inhibitor of protein phosphatase 1 (PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo. J Biol Chem (2002) 1.21
Crystal structure of M-Ras reveals a GTP-bound "off" state conformation of Ras family small GTPases. J Biol Chem (2005) 1.21
Activation of the small GTPase Rac1 by a specific guanine-nucleotide-exchange factor suffices to induce glucose uptake into skeletal-muscle cells. Biol Cell (2008) 1.19
Draxin, a repulsive guidance protein for spinal cord and forebrain commissures. Science (2009) 1.17
Fez1 is layer-specifically expressed in the adult mouse neocortex. Eur J Neurosci (2004) 1.17
The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol (2009) 1.13
Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon. Mol Cell Biol (2005) 1.08
Solution structure of the state 1 conformer of GTP-bound H-Ras protein and distinct dynamic properties between the state 1 and state 2 conformers. J Biol Chem (2011) 1.07
Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1. Development (2009) 1.05
Phospholipase Cepsilon regulates ovulation in Caenorhabditis elegans. Dev Biol (2004) 1.05
Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an apolipoprotein E receptor/disabled-1/glycogen synthase kinase-3beta cascade. FASEB J (2002) 1.03
Requirement of activated Cdc42-associated kinase for survival of v-Ras-transformed mammalian cells. Mol Cancer Res (2005) 1.03
Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome. Biochem Biophys Res Commun (2009) 1.02
Rac1 in cortical projection neurons is selectively required for midline crossing of commissural axonal formation. Eur J Neurosci (2008) 1.00
Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants. FEBS Lett (2012) 1.00
Adenovirus-mediated gene transfer in olfactory epithelium and olfactory bulb: a long-term study. Ann Otol Rhinol Laryngol (2005) 0.98
Neuronal lineage-specific induction of phospholipase Cepsilon expression in the developing mouse brain. Eur J Neurosci (2003) 0.96
Two conformational states of Ras GTPase exhibit differential GTP-binding kinetics. Biochem Biophys Res Commun (2008) 0.95
Role of the Sec14-like domain of Dbl family exchange factors in the regulation of Rho family GTPases in different subcellular sites. Cell Signal (2004) 0.94
Dorsal telencephalon-specific RA-GEF-1 knockout mice develop heterotopic cortical mass and commissural fiber defect. Eur J Neurosci (2009) 0.94
Fezf1 is required for penetration of the basal lamina by olfactory axons to promote olfactory development. J Comp Neurol (2009) 0.93
Dynamic polymorphism of Ras observed by single molecule FRET is the basis for molecular recognition. Biochem Biophys Res Commun (2006) 0.92
PLCε cooperates with the NF-κB pathway to augment TNFα-stimulated CCL2/MCP1 expression in human keratinocyte. Biochem Biophys Res Commun (2011) 0.91
Unusual patch-matrix organization in the retrosplenial cortex of the reeler mouse and Shaking rat Kawasaki. Cereb Cortex (2007) 0.91
Crucial role of phospholipase Cepsilon in induction of local skin inflammatory reactions in the elicitation stage of allergic contact hypersensitivity. J Immunol (2009) 0.91
Macroscopic and histological observations on the human sternoclavicular joint disc. Anat Sci Int (2009) 0.89
Role of RalA downstream of Rac1 in insulin-dependent glucose uptake in muscle cells. Cell Signal (2012) 0.88
Akt2 regulates Rac1 activity in the insulin-dependent signaling pathway leading to GLUT4 translocation to the plasma membrane in skeletal muscle cells. Cell Signal (2013) 0.88
Detailed structural analysis of lipids directly on tissue specimens using a MALDI-SpiralTOF-Reflectron TOF mass spectrometer. PLoS One (2012) 0.87
Structural analysis of triacylglycerols by using a MALDI-TOF/TOF system with monoisotopic precursor selection. J Am Soc Mass Spectrom (2012) 0.87
Critical function of the Ras-associating domain as a primary Ras-binding site for regulation of Saccharomyces cerevisiae adenylyl cyclase. J Biol Chem (2001) 0.87
Developmental anatomy of reeler mutant mouse. Dev Growth Differ (2009) 0.87
Phospholipase Cɛ has a crucial role in ultraviolet B-induced neutrophil-associated skin inflammation by regulating the expression of CXCL1/KC. Lab Invest (2011) 0.87
Regulation of mitotic spindle formation by the RhoA guanine nucleotide exchange factor ARHGEF10. BMC Cell Biol (2009) 0.86
Enhancement of ultraviolet B-induced skin tumor development in phospholipase Cε-knockout mice is associated with decreased cell death. Carcinogenesis (2010) 0.86
Identification of a novel domain of Ras and Rap1 that directs their differential subcellular localizations. J Biol Chem (2004) 0.86
Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice. Glia (2013) 0.86
Overexpression of phospholipase Cε in keratinocytes upregulates cytokine expression and causes dermatitis with acanthosis and T-cell infiltration. Eur J Immunol (2010) 0.85
PKH26 is an excellent retrograde and anterograde fluorescent tracer characterized by a small injection site and strong fluorescence emission. Arch Histol Cytol (2010) 0.85
Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1. Biochem Biophys Res Commun (2009) 0.85
Defective vascular morphogenesis and mid-gestation embryonic death in mice lacking RA-GEF-1. Biochem Biophys Res Commun (2007) 0.84
Phospholipase Cepsilon guanine nucleotide exchange factor activity and activation of Rap1. Methods Enzymol (2006) 0.84
Critical roles of interactions among switch I-preceding residues and between switch II and its neighboring alpha-helix in conformational dynamics of the GTP-bound Ras family small GTPases. J Biol Chem (2011) 0.84
Fukuyama-type congenital muscular dystrophy (FCMD) and alpha-dystroglycanopathy. Congenit Anom (Kyoto) (2003) 0.84
Morphological analysis of the branches of the dorsal pancreatic artery and their clinical significance. Clin Anat (2013) 0.83
The superficial layers of the superior colliculus are cytoarchitectually and myeloarchitectually disorganized in the reelin-deficient mouse, reeler. Brain Res (2006) 0.83
Role of the guanine nucleotide exchange factor Ost in negative regulation of receptor endocytosis by the small GTPase Rac1. J Biol Chem (2007) 0.83
Dispersion of the neurons expressing layer specific markers in the reeler brain. Dev Growth Differ (2010) 0.82
Cytoarchitecture and fiber pattern of the superior colliculus are disrupted in the Shaking Rat Kawasaki. Brain Res Dev Brain Res (2003) 0.81
H-Ras/mitogen-activated protein kinase pathway inhibits integrin-mediated adhesion and induces apoptosis in osteoblasts. J Biol Chem (2002) 0.81
Ectopic corticospinal tract and corticothalamic tract neurons in the cerebral cortex of yotari and reeler mice. J Comp Neurol (2003) 0.81
Expression of strawberry notch family genes during zebrafish embryogenesis. Dev Dyn (2010) 0.81
A mouse homologue of Strawberry Notch is transcriptionally regulated by Reelin signal. Biochem Biophys Res Commun (2006) 0.80
Short- and long-term outcomes of compromised side branches after Multi-Link stent implantation. Heart Vessels (2002) 0.80
Function of strawberry notch family genes in the zebrafish brain development. Kobe J Med Sci (2011) 0.80
Missplicing resulting from a short deletion in the reelin gene causes reeler-like neuronal disorders in the mutant shaking rat Kawasaki. J Comp Neurol (2003) 0.80
Establishment of framework of the cortical area is influenced by Otx1. Neurosci Res (2008) 0.80
Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein. Biochem Biophys Res Commun (2003) 0.80
A critical role of the small GTPase Rac1 in Akt2-mediated GLUT4 translocation in mouse skeletal muscle. FEBS J (2014) 0.79
Ras and Rap1 activation of PLCepsilon lipase activity. Methods Enzymol (2006) 0.79
Direct activation of fission yeast adenylyl cyclase by heterotrimeric G protein gpa2. Kobe J Med Sci (2004) 0.79
Expression of reelin in the dorsal cochlear nucleus of the mouse. Brain Res Dev Brain Res (2005) 0.79