Published in BMC Bioinformatics on August 31, 2011
Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Hum Mol Genet (2013) 1.32
Protein complex-based analysis framework for high-throughput data sets. Sci Signal (2013) 1.20
Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. Sci Signal (2011) 1.20
Mouse genetic and phenotypic resources for human genetics. Hum Mutat (2012) 1.18
UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents. Genetics (2013) 1.14
FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update. Nucleic Acids Res (2011) 1.11
FlyPrimerBank: an online database for Drosophila melanogaster gene expression analysis and knockdown evaluation of RNAi reagents. G3 (Bethesda) (2013) 1.09
Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Am J Hum Genet (2013) 1.06
The Transgenic RNAi Project at Harvard Medical School: Resources and Validation. Genetics (2015) 1.04
Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase. Proc Natl Acad Sci U S A (2015) 1.01
FlyBase at 25: looking to the future. Nucleic Acids Res (2016) 0.97
Conserved regulators of nucleolar size revealed by global phenotypic analyses. Sci Signal (2013) 0.95
Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster. PLoS Genet (2016) 0.94
Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos. Dev Cell (2014) 0.94
FlyBase portals to human disease research using Drosophila models. Dis Model Mech (2016) 0.92
A genetic basis for the variable effect of smoking/nicotine on Parkinson's disease. Pharmacogenomics J (2012) 0.91
GLAD: an Online Database of Gene List Annotation for Drosophila. J Genomics (2015) 0.91
RhoA GTPase inhibition organizes contraction during epithelial morphogenesis. J Cell Biol (2016) 0.88
Resources for functional genomics studies in Drosophila melanogaster. Genetics (2014) 0.88
Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease. Mol Cell Biol (2016) 0.86
Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy. Proc Natl Acad Sci U S A (2014) 0.85
Network analyses reveal novel aspects of ALS pathogenesis. PLoS Genet (2015) 0.82
The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster. Environ Health Perspect (2016) 0.82
Beyond antioxidant genes in the ancient Nrf2 regulatory network. Free Radic Biol Med (2015) 0.80
Drosophila and experimental neurology in the post-genomic era. Exp Neurol (2015) 0.80
Modeling congenital disease and inborn errors of development in Drosophila melanogaster. Dis Model Mech (2016) 0.79
A quantitative genome-wide RNAi screen in C. elegans for antifungal innate immunity genes. BMC Biol (2016) 0.79
Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals. PLoS Genet (2015) 0.79
Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets. Proc Natl Acad Sci U S A (2016) 0.79
Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology. Mol Psychiatry (2016) 0.78
Functional Conservation of the Glide/Gcm Regulatory Network Controlling Glia, Hemocyte, and Tendon Cell Differentiation in Drosophila. Genetics (2015) 0.78
Quantitative analysis of the murine lipid droplet-associated proteome during diet-induced hepatic steatosis. J Lipid Res (2015) 0.78
Vilya, a component of the recombination nodule, is required for meiotic double-strand break formation in Drosophila. Elife (2015) 0.78
Enhancer modeling uncovers transcriptional signatures of individual cardiac cell states in Drosophila. Nucleic Acids Res (2015) 0.77
Identification of Drosophila Zfh2 as a Mediator of Hypercapnic Immune Regulation by a Genome-Wide RNA Interference Screen. J Immunol (2015) 0.77
Identification of genes associated with resilience/vulnerability to sleep deprivation and starvation in Drosophila. Sleep (2015) 0.77
PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications. BMC Genomics (2015) 0.77
Drosophila and Caenorhabditis elegans as Discovery Platforms for Genes Involved in Human Alcohol Use Disorder. Alcohol Clin Exp Res (2015) 0.77
A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis. Biol Open (2014) 0.77
Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits. Dis Model Mech (2017) 0.77
Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Genome Biol (2017) 0.77
High throughput in vivo functional validation of candidate congenital heart disease genes in Drosophila. Elife (2017) 0.76
FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update. Nucleic Acids Res (2016) 0.76
EHFPI: a database and analysis resource of essential host factors for pathogenic infection. Nucleic Acids Res (2014) 0.76
MECP2 impairs neuronal structure by regulating KIBRA. Neurobiol Dis (2016) 0.76
Circadian deep sequencing reveals stress-response genes that adopt robust rhythmic expression during aging. Nat Commun (2017) 0.76
Zfrp8 forms a complex with fragile-X mental retardation protein and regulates its localization and function. Dev Biol (2016) 0.76
Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes. Genome Res (2017) 0.75
WORMHOLE: Novel Least Diverged Ortholog Prediction through Machine Learning. PLoS Comput Biol (2016) 0.75
Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Syst (2017) 0.75
Testing candidate genes for attention-deficit/hyperactivity disorder in fruit flies using a high throughput assay for complex behavior. Fly (Austin) (2016) 0.75
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles. Sci Rep (2016) 0.75
Exploring FlyBase Data Using QuickSearch. Curr Protoc Bioinformatics (2016) 0.75
The Drosophila Gene Expression Tool (DGET) for expression analyses. BMC Bioinformatics (2017) 0.75
Neurological disorders: towards a mechanistic understanding of restless legs syndrome. Curr Biol (2012) 0.75
Using FlyBase, a Database of Drosophila Genes and Genomes. Methods Mol Biol (2016) 0.75
miR-263a Regulates ENaC to Maintain Osmotic and Intestinal Stem Cell Homeostasis in Drosophila. Dev Cell (2016) 0.75
Insights into ALS pathomechanisms: from flies to humans. Fly (Austin) (2015) 0.75
Genetic determinants of phosphate response in Drosophila. PLoS One (2013) 0.75
Identification of Novel Regulators of the JAK/STAT Signaling Pathway that Control Border Cell Migration in the Drosophila Ovary. G3 (Bethesda) (2016) 0.75
Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS. PLoS Genet (2017) 0.75
Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila. BMC Genomics (2016) 0.75
An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis. PLoS One (2015) 0.75
Modeling Monogenic Human Nephrotic Syndrome in the Drosophila Garland Cell Nephrocyte. J Am Soc Nephrol (2016) 0.75
The translation factors of Drosophila melanogaster. Fly (Austin) (2016) 0.75
A Personalized Model of COQ2 Nephropathy Rescued by the Wild-Type COQ2 Allele or Dietary Coenzyme Q10 Supplementation. J Am Soc Nephrol (2017) 0.75
Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo. Sci Rep (2017) 0.75
Multifunctional glial support by Semper cells in the Drosophila retina. PLoS Genet (2017) 0.75
Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species. Oncogene (2017) 0.75
Genome-wide identification of Grainy head targets in Drosophila reveals regulatory interactions with the POU-domain transcription factor, Vvl. Development (2017) 0.75
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. Nucleic Acids Res (2017) 0.75
The COG database: an updated version includes eukaryotes. BMC Bioinformatics (2003) 60.98
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
OrthoMCL: identification of ortholog groups for eukaryotic genomes. Genome Res (2003) 33.03
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res (2005) 30.44
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2001) 19.13
McKusick's Online Mendelian Inheritance in Man (OMIM). Nucleic Acids Res (2008) 12.83
EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates. Genome Res (2008) 12.72
Extending healthy life span--from yeast to humans. Science (2010) 12.12
Inparanoid: a comprehensive database of eukaryotic orthologs. Nucleic Acids Res (2005) 9.90
TreeFam: a curated database of phylogenetic trees of animal gene families. Nucleic Acids Res (2006) 8.83
Online Mendelian Inheritance in Man (OMIM). Hum Mutat (2000) 7.54
Assessing performance of orthology detection strategies applied to eukaryotic genomes. PLoS One (2007) 5.62
Annotating the human genome with Disease Ontology. BMC Genomics (2009) 4.71
Phylogenetic and functional assessment of orthologs inference projects and methods. PLoS Comput Biol (2009) 4.65
An open access database of genome-wide association results. BMC Med Genet (2009) 4.61
A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nat Methods (2011) 4.24
Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation. Cell Host Microbe (2009) 4.21
Automatic clustering of orthologs and inparalogs shared by multiple proteomes. Bioinformatics (2006) 3.98
Benchmarking ortholog identification methods using functional genomics data. Genome Biol (2006) 3.54
PhylomeDB: a database for genome-wide collections of gene phylogenies. Nucleic Acids Res (2007) 3.30
Roundup: a multi-genome repository of orthologs and evolutionary distances. Bioinformatics (2006) 3.28
GOSemSim: an R package for measuring semantic similarity among GO terms and gene products. Bioinformatics (2010) 3.20
Using literature-based discovery to identify disease candidate genes. Int J Med Inform (2005) 3.16
Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila. Cell Metab (2007) 2.99
Global alignment of multiple protein interaction networks with application to functional orthology detection. Proc Natl Acad Sci U S A (2008) 2.85
A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Res (2001) 2.73
OrthoDisease: a database of human disease orthologs. Hum Mutat (2004) 2.52
Systematic identification of functional orthologs based on protein network comparison. Genome Res (2006) 2.47
A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics (2009) 2.45
FlyRNAi: the Drosophila RNAi screening center database. Nucleic Acids Res (2006) 2.43
How confident can we be that orthologs are similar, but paralogs differ? Trends Genet (2009) 2.21
Analysis of genomic and proteomic data using advanced literature mining. J Proteome Res (2003) 2.16
OMA Browser--exploring orthologous relations across 352 complete genomes. Bioinformatics (2007) 2.07
IsoRankN: spectral methods for global alignment of multiple protein networks. Bioinformatics (2009) 2.04
Joining forces in the quest for orthologs. Genome Biol (2009) 1.96
Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. Hum Mol Genet (2006) 1.77
GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique. BMC Bioinformatics (2008) 1.75
HCOP: a searchable database of human orthology predictions. Brief Bioinform (2006) 1.73
Functional proteomics approach to investigate the biological activities of cDNAs implicated in breast cancer. J Proteome Res (2006) 1.66
Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa infection. Nat Protoc (2009) 1.59
A drosophila model for EGFR-Ras and PI3K-dependent human glioma. PLoS Genet (2009) 1.43
Homophila: human disease gene cognates in Drosophila. Nucleic Acids Res (2002) 1.40
The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences. Proc Natl Acad Sci U S A (1999) 1.39
NetworkBLAST: comparative analysis of protein networks. Bioinformatics (2008) 1.37
The genetics of mental retardation. Hum Mol Genet (2006) 1.34
OrthoInspector: comprehensive orthology analysis and visual exploration. BMC Bioinformatics (2011) 1.25
HCOP: the HGNC comparison of orthology predictions search tool. Mamm Genome (2005) 1.20
Getting started in gene orthology and functional analysis. PLoS Comput Biol (2010) 1.20
A Drosophila model of oculopharyngeal muscular dystrophy reveals intrinsic toxicity of PABPN1. EMBO J (2006) 1.18
Adult Drosophila melanogaster as a model for the study of glucose homeostasis. Aging (Albany NY) (2010) 1.18
Drosophila embryos as model systems for monitoring bacterial infection in real time. PLoS Pathog (2009) 1.12
IsoBase: a database of functionally related proteins across PPI networks. Nucleic Acids Res (2011) 1.05
Comparison of the oxidative phosphorylation (OXPHOS) nuclear genes in the genomes of Drosophila melanogaster, Drosophila pseudoobscura and Anopheles gambiae. Genome Biol (2005) 1.05
Drosophila as a model to study cardiac aging. Exp Gerontol (2010) 1.03
Kismet/CHD7 regulates axon morphology, memory and locomotion in a Drosophila model of CHARGE syndrome. Hum Mol Genet (2010) 1.00
On the naming of clinical disorders, with particular reference to eponyms. Medicine (Baltimore) (1998) 0.96
Modeling migration and metastasis in Drosophila. J Mammary Gland Biol Neoplasia (2007) 0.95
Chronic hypoxia impairs muscle function in the Drosophila model of Duchenne's muscular dystrophy (DMD). PLoS One (2010) 0.95
The nuclear OXPHOS genes in insecta: a common evolutionary origin, a common cis-regulatory motif, a common destiny for gene duplicates. BMC Evol Biol (2007) 0.93
Drosophila as a novel therapeutic discovery tool for thyroid cancer. Thyroid (2010) 0.90
Drosophila melanogaster as a model host for the Burkholderia cepacia complex. PLoS One (2010) 0.88
Drosophila as a lipotoxicity model organism--more than a promise? Biochim Biophys Acta (2009) 0.88
CSI-OMIM--Clinical Synopsis Search in OMIM. BMC Bioinformatics (2011) 0.87
Drosophila in asthma research. Am J Respir Crit Care Med (2009) 0.85
COMPARE, a multi-organism system for cross-species data comparison and transfer of information. Bioinformatics (2007) 0.85
A Drosophila model for primary coenzyme Q deficiency and dietary rescue in the developing nervous system. Dis Model Mech (2010) 0.82
The fruit fly as a meeting place for microbes. Cell Host Microbe (2008) 0.80
Increased apoptosis of myoblasts in Drosophila model for the Walker-Warburg syndrome. PLoS One (2010) 0.79
Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy. Int J Alzheimers Dis (2010) 0.79
Linking model systems to cancer therapeutics: the case of Mastermind. Dis Model Mech (2010) 0.78
A framework for comparing phenotype annotations of orthologous genes. Stud Health Technol Inform (2010) 0.78
The Drosophila 7-pass transmembrane glycoprotein BOSS and metabolic regulation: What Drosophila can teach us about human energy metabolism. Methods Enzymol (2010) 0.78
Properties of ecdysteroid receptors from diverse insect species in a heterologous cell culture system--a basis for screening novel insecticidal candidates. FEBS J (2009) 0.77
ARACHNE: a whole-genome shotgun assembler. Genome Res (2002) 22.72
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
The developmental transcriptome of Drosophila melanogaster. Nature (2010) 11.85
An endogenous small interfering RNA pathway in Drosophila. Nature (2008) 7.88
Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science (2004) 7.75
An empirical framework for binary interactome mapping. Nat Methods (2008) 6.59
The promise and perils of Wnt signaling through beta-catenin. Science (2002) 6.11
Minimizing the risk of reporting false positives in large-scale RNAi screens. Nat Methods (2006) 5.96
Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature (2005) 5.86
Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nat Genet (2008) 5.50
Herpesviral protein networks and their interaction with the human proteome. Science (2005) 4.74
Functional genomic analysis of the Wnt-wingless signaling pathway. Science (2005) 4.73
A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nat Methods (2011) 4.24
Sequential activation of signaling pathways during innate immune responses in Drosophila. Dev Cell (2002) 4.08
Heparan sulphate proteoglycans: the sweet side of development. Nat Rev Mol Cell Biol (2005) 3.92
Droplet microfluidic technology for single-cell high-throughput screening. Proc Natl Acad Sci U S A (2009) 3.85
Quantitative morphological signatures define local signaling networks regulating cell morphology. Science (2007) 3.76
Functional genomics reveals genes involved in protein secretion and Golgi organization. Nature (2006) 3.72
Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection. Science (2005) 3.49
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLoS Biol (2004) 3.39
Integrated activity of PDZ protein complexes regulates epithelial polarity. Nat Cell Biol (2003) 3.38
Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays. Nat Methods (2006) 3.29
Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science (2005) 3.28
High-throughput RNAi screening in cultured cells: a user's guide. Nat Rev Genet (2006) 3.22
Hierarchical rules for Argonaute loading in Drosophila. Mol Cell (2009) 3.20
The emergence of geometric order in proliferating metazoan epithelia. Nature (2006) 3.13
Genomic screening with RNAi: results and challenges. Annu Rev Biochem (2010) 3.08
Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Dev Cell (2003) 3.05
A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Nature (2006) 3.00
GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo. Gene Expr Patterns (2006) 2.96
Global alignment of multiple protein interaction networks with application to functional orthology detection. Proc Natl Acad Sci U S A (2008) 2.85
Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition. Genes Dev (2005) 2.83
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell (2010) 2.66
Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila. Genes Dev (2005) 2.63
Temperature-sensitive control of protein activity by conditionally splicing inteins. Nat Biotechnol (2004) 2.62
Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Nat Methods (2007) 2.59
A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. Nat Cell Biol (2013) 2.59
Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Res (2010) 2.56
Inferring admixture histories of human populations using linkage disequilibrium. Genetics (2013) 2.51
The transcriptional diversity of 25 Drosophila cell lines. Genome Res (2010) 2.47
Diversity and dynamics of the Drosophila transcriptome. Nature (2014) 2.47
A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics (2009) 2.45
FlyRNAi: the Drosophila RNAi screening center database. Nucleic Acids Res (2006) 2.43
Matt: local flexibility aids protein multiple structure alignment. PLoS Comput Biol (2008) 2.41
The roles of JAK/STAT signaling in Drosophila immune responses. Immunol Rev (2004) 2.37
A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nat Genet (2005) 2.26
Muscle mitohormesis promotes longevity via systemic repression of insulin signaling. Cell (2013) 2.21
Methods in comparative genomics: genome correspondence, gene identification and regulatory motif discovery. J Comput Biol (2004) 2.20
Genetic screening for signal transduction in the era of network biology. Cell (2007) 2.19
HIPPIE: Integrating protein interaction networks with experiment based quality scores. PLoS One (2012) 2.17
Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proc Natl Acad Sci U S A (2013) 2.13
Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells. PLoS One (2008) 2.10
Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. Cell (2012) 2.06
The PDGF/VEGF receptor controls blood cell survival in Drosophila. Dev Cell (2004) 2.06
The Jak/STAT pathway in model organisms: emerging roles in cell movement. Dev Cell (2002) 2.05
Design and implementation of high-throughput RNAi screens in cultured Drosophila cells. Nat Protoc (2007) 2.05
Control of the mitotic cleavage plane by local epithelial topology. Cell (2011) 2.04
Pertactin beta-helix folding mechanism suggests common themes for the secretion and folding of autotransporter proteins. Proc Natl Acad Sci U S A (2006) 2.04
IsoRankN: spectral methods for global alignment of multiple protein networks. Bioinformatics (2009) 2.04
Molecular mechanisms of epithelial morphogenesis. Annu Rev Cell Dev Biol (2002) 2.00
Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. Mol Cell (2008) 1.95
COPI activity coupled with fatty acid biosynthesis is required for viral replication. PLoS Pathog (2006) 1.95
Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis. Nat Immunol (2003) 1.90
The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration. Development (2010) 1.89
Synergy between bacterial infection and genetic predisposition in intestinal dysplasia. Proc Natl Acad Sci U S A (2009) 1.88
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds. Science (2008) 1.86
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. Cancer Cell (2013) 1.86
MSARI: multiple sequence alignments for statistical detection of RNA secondary structure. Proc Natl Acad Sci U S A (2004) 1.85
High-throughput RNA interference screens in Drosophila tissue culture cells. Methods Enzymol (2005) 1.83
Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing. Science (2005) 1.81
A novel missense mutation in SLC34A3 that causes hereditary hypophosphatemic rickets with hypercalciuria in humans identifies threonine 137 as an important determinant of sodium-phosphate cotransport in NaPi-IIc. Am J Physiol Renal Physiol (2008) 1.81
Drosophila and the genetics of the internal milieu. Nature (2007) 1.79
Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis. Dev Biol (2003) 1.79
Ancient west Eurasian ancestry in southern and eastern Africa. Proc Natl Acad Sci U S A (2014) 1.79
In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nat Methods (2007) 1.78
The genetic prehistory of southern Africa. Nat Commun (2012) 1.78
Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype. J Cell Biol (2011) 1.75
Genetic evidence for recent population mixture in India. Am J Hum Genet (2013) 1.73
Compressive genomics. Nat Biotechnol (2012) 1.66
Genetic evidence of serum phosphate-independent functions of FGF-23 on bone. PLoS Genet (2008) 1.63
A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway. Genetics (2003) 1.63
Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3'UTRs. Proc Natl Acad Sci U S A (2010) 1.62
Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity. Development (2005) 1.62
neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions. Development (2003) 1.60
Identification of neural outgrowth genes using genome-wide RNAi. PLoS Genet (2008) 1.60
Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy. PLoS Biol (2013) 1.59
Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. RNA (2009) 1.57
Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs. Genome Res (2011) 1.53
Functional screening identifies miR-315 as a potent activator of Wingless signaling. Proc Natl Acad Sci U S A (2007) 1.53
Analysis of twenty-four Gal4 lines in Drosophila melanogaster. Genesis (2002) 1.51
A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proc Natl Acad Sci U S A (2007) 1.50
Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins. Mol Cell (2011) 1.49
Hedgehog signal transduction: recent findings. Curr Opin Genet Dev (2002) 1.48
RNAi screening: new approaches, understandings, and organisms. Wiley Interdiscip Rev RNA (2011) 1.48
Cellular phenotype recognition for high-content RNA interference genome-wide screening. J Biomol Screen (2008) 1.47