Published in Cancer Gene Ther on September 16, 2011
Cloning and expression of soluble vascular endothelial growth factors receptor-1 (sFlt-1) fragments in CHO-K1. Int J Clin Exp Med (2013) 0.77
The synergistic effects of low dose fluorouracil and TRAIL on TRAIL-resistant human gastric adenocarcinoma AGS cells. Biomed Res Int (2013) 0.77
A Phytase-Based Reporter System for Identification of Functional Secretion Signals in Bifidobacteria. PLoS One (2015) 0.76
Targeted Cancer Therapy Using Engineered Salmonella typhimurium. Chonnam Med J (2016) 0.75
Delivery of sFIT-1 engineered MSCs in combination with a continuous low-dose doxorubicin treatment prevents growth of liver cancer. Aging (Albany NY) (2016) 0.75
Validation of Bevacizumab Therapy Effect on Colon Cancer Subtypes by Using Whole Body Imaging in Mice. Mol Imaging Biol (2017) 0.75
Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma. N Engl J Med (1991) 19.46
Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell (1997) 13.94
Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance. Gut (2003) 2.37
Cyclooxygenase-2 overexpression correlates with vascular endothelial growth factor expression and tumor angiogenesis in gastric cancer. J Clin Gastroenterol (2003) 2.03
Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors. Breast Cancer Res Treat (2001) 1.88
The effect of over-expression of sFlt-1 on blood pressure and the occurrence of other manifestations of preeclampsia in unrestrained conscious pregnant mice. Am J Obstet Gynecol (2007) 1.65
Bifidobacterium longum as a delivery system for cancer gene therapy: selective localization and growth in hypoxic tumors. Cancer Gene Ther (2000) 1.62
Variants in IL28B in liver recipients and donors correlate with response to peg-interferon and ribavirin therapy for recurrent hepatitis C. Gastroenterology (2010) 1.47
Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia/necrosis. Gene Ther (2002) 1.37
VEGF in brain tumors. J Neurooncol (2001) 1.33
Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice. BMC Cancer (2009) 1.30
Tumor cavitation during therapy with antiangiogenesis agents in patients with lung cancer. J Thorac Oncol (2008) 1.29
Adeno-associated virus vectors: potential applications for cancer gene therapy. Cancer Gene Ther (2005) 1.19
Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity. Clin Cancer Res (2003) 1.14
Hypoxia-inducible factor-1alpha is associated with risk of aggressive behavior and tumor angiogenesis in gastrointestinal stromal tumor. Jpn J Clin Oncol (2005) 1.13
Vascular endothelial growth factor is necessary in the development of arteriosclerosis by recruiting/activating monocytes in a rat model of long-term inhibition of nitric oxide synthesis. Circulation (2002) 1.05
Antiangiogenic gene therapy with systemically administered sFlt-1 plasmid DNA in engineered gelatin-based nanovectors. Cancer Gene Ther (2007) 1.02
Antiangiogenesis for cancer therapy. Lancet (1997) 1.02
Bifidobacterium adolescentis as a delivery system of endostatin for cancer gene therapy: selective inhibitor of angiogenesis and hypoxic tumor growth. Cancer Gene Ther (2003) 1.01
Challenges of antiangiogenic cancer therapy: trials and errors, and renewed hope. J Cell Mol Med (2007) 1.00
sFlt-1 gene therapy of follicular thyroid carcinoma. Endocrinology (2003) 0.99
Essential role of vascular endothelial growth factor and Flt-1 signals in neointimal formation after periadventitial injury. Arterioscler Thromb Vasc Biol (2004) 0.99
Bifidobacterium longum as a delivery system of TRAIL and endostatin cooperates with chemotherapeutic drugs to inhibit hypoxic tumor growth. Cancer Gene Ther (2009) 0.95
Gene transfer of pigment epithelium-derived factor suppresses tumor growth and angiogenesis in a hepatoblastoma xenograft model. Pediatr Res (2006) 0.90
Soluble Fms-like tyrosine kinase-1 expression inhibits the growth of multiple myeloma in nude mice. Acta Biochim Biophys Sin (Shanghai) (2007) 0.89
Antitumor effect of cytosine deaminase/5-fluorocytosine suicide gene therapy system mediated by Bifidobacterium infantis on melanoma. Acta Pharmacol Sin (2005) 0.89
Mode of action and clinical impact of VEGF signaling inhibitors. Expert Rev Anticancer Ther (2009) 0.86
Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor. Cancer Gene Ther (2005) 0.84
Suppression of lung metastasis of renal cell carcinoma by the intramuscular gene transfer of a soluble form of vascular endothelial growth factor receptor I. J Urol (2004) 0.83
Prognostic significance of tumor angiogenesis in epithelial ovarian cancer: in association with transforming growth factor beta and vascular endothelial growth factor. Int J Gynecol Cancer (2004) 0.83
Oncolytic adenovirus-mediated transfer of the antisense chk2 selectively inhibits tumor growth in vitro and in vivo. Cancer Gene Ther (2006) 0.83
Overexpression of cyclooxygenase-2 correlates with tumor angiogenesis in endometrial carcinoma. Int J Gynecol Cancer (2006) 0.82
Antiangiogenesis: the fifth cancer treatment modality? Oncol Nurs Forum (2003) 0.81
Neural migration disorders studied by cerebral ultrasound and colour Doppler flow imaging. Arch Dis Child Fetal Neonatal Ed (1995) 0.80
Systemic inhibition of tumor growth by soluble Flk-1 gene therapy combined with cisplatin. Cancer Gene Ther (2006) 0.80
Significance of microvascular density (MVD) in cervical cancer recurrence. Int J Gynecol Cancer (2003) 0.80
Estimation of breast prosthesis volume by the Cavalieri principle using magnetic resonance images. Aesthetic Plast Surg (2005) 0.80
Paracrine action of sFLT-1 secreted by stably-transfected Ehrlich ascites tumor cells and therapy using sFLT-1 inhibits ascites tumor growth in vivo. J Gene Med (2009) 0.78
Stereological evaluation of laryngeal cancers using computed tomography via the Cavalieri method: correlation between tumor volume and number of neck lymph node metastases. J Craniofac Surg (2009) 0.76
[Construction and expression of soluble vascular endothelial growth factor receptor-1 eukaryotic expression vector and its effect on proliferation of vascular endothelial cells]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi (2010) 0.76
Bevacizumab in combination with sequential high-dose chemotherapy in solid cancer, a feasibility study. Bone Marrow Transplant (2010) 0.76
The sequence of the human genome. Science (2001) 101.55
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Comparative genomics of the eukaryotes. Science (2000) 26.62
A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci U S A (1998) 24.58
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature (1996) 20.59
Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science (1998) 17.91
Stat3 as an oncogene. Cell (1999) 17.39
Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli. Proc Natl Acad Sci U S A (2002) 13.83
TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature (2001) 11.84
The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol (2000) 10.20
Room-temperature ultraviolet nanowire nanolasers. Science (2001) 9.79
Global burden of obesity in 2005 and projections to 2030. Int J Obes (Lond) (2008) 9.45
Effect of statins on risk of coronary disease: a meta-analysis of randomized controlled trials. JAMA (1999) 9.18
Differences in risk factors, atherosclerosis, and cardiovascular disease between ethnic groups in Canada: the Study of Health Assessment and Risk in Ethnic groups (SHARE) Lancet (2000) 8.01
U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact. Dig Dis Sci (1993) 7.98
Positional cloning of the mouse circadian clock gene. Cell (1997) 7.79
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. Cell (1995) 7.73
Robust perfect adaptation in bacterial chemotaxis through integral feedback control. Proc Natl Acad Sci U S A (2000) 7.67
Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease. N Engl J Med (2009) 7.53
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein. Science (1999) 7.51
Hepatic arterial infusion of chemotherapy after resection of hepatic metastases from colorectal cancer. N Engl J Med (1999) 7.04
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature (1999) 6.37
Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J (1996) 6.36
Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention. N Engl J Med (1999) 6.27
Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev (1996) 6.01
Human Smad3 and Smad4 are sequence-specific transcription activators. Mol Cell (1998) 5.88
The evolution of H5N1 influenza viruses in ducks in southern China. Proc Natl Acad Sci U S A (2004) 5.87
Hyperpolarizing vasodilators activate ATP-sensitive K+ channels in arterial smooth muscle. Science (1989) 5.60
Convergent domestication of cereal crops by independent mutations at corresponding genetic Loci. Science (1995) 5.52
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue. Cell (1997) 5.51
Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2. Nat Med (1999) 5.50
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm. Genes Dev (2001) 5.41
Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J Natl Cancer Inst (2001) 5.24
Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T. Infect Immun (2003) 5.11
Indium phosphide nanowires as building blocks for nanoscale electronic and optoelectronic devices. Nature (2001) 5.09
Inhibition of JNK activation through NF-kappaB target genes. Nature (2001) 5.03
SOX9 directly regulates the type-II collagen gene. Nat Genet (1997) 4.88
American College of Rheumatology classification criteria for Sjögren's syndrome: a data-driven, expert consensus approach in the Sjögren's International Collaborative Clinical Alliance cohort. Arthritis Care Res (Hoboken) (2012) 4.82
A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum. Science (1999) 4.75
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy. Nat Genet (1998) 4.75
In vivo evidence of structural brain asymmetry in musicians. Science (1995) 4.71
Trend tests for case-control studies of genetic markers: power, sample size and robustness. Hum Hered (2002) 4.64
Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature (1997) 4.59
HIV infection is blocked in vitro by recombinant soluble CD4. Nature (1988) 4.58
Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. J Clin Endocrinol Metab (2001) 4.53
Electrostatic interactions of S4 voltage sensor in Shaker K+ channel. Neuron (1995) 4.49
Phase-resolved optical coherence tomography and optical Doppler tomography for imaging blood flow in human skin with fast scanning speed and high velocity sensitivity. Opt Lett (2000) 4.33
Identification of a chlamydial protease-like activity factor responsible for the degradation of host transcription factors. J Exp Med (2001) 4.27
Folding funnels, binding funnels, and protein function. Protein Sci (1999) 4.22
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. J Clin Invest (2000) 4.16
Separation of human breast cancer cells from blood by differential dielectric affinity. Proc Natl Acad Sci U S A (1995) 4.00
Nucleotide sequence of the G protein gene of human respiratory syncytial virus reveals an unusual type of viral membrane protein. Proc Natl Acad Sci U S A (1985) 3.93
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene. Proc Natl Acad Sci U S A (1996) 3.88
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell (1998) 3.79
Synthesis and fungicidal activity against Rhizoctonia solani of 2-alkyl (Alkylthio)-5-pyrazolyl-1,3,4-oxadiazoles (Thiadiazoles). J Agric Food Chem (2000) 3.78
Folding and binding cascades: dynamic landscapes and population shifts. Protein Sci (2000) 3.74
The presynaptic particle web: ultrastructure, composition, dissolution, and reconstitution. Neuron (2001) 3.68
Unconventional myosins in inner-ear sensory epithelia. J Cell Biol (1997) 3.64
Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta). J Biol Chem (1996) 3.63
Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J Biol Chem (1996) 3.63
Cincinnati Prehospital Stroke Scale: reproducibility and validity. Ann Emerg Med (1999) 3.54
Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content. J Appl Physiol (1985) (2000) 3.54
Mega-dose vitamins and minerals in the treatment of non-metastatic breast cancer: an historical cohort study. Breast Cancer Res Treat (2002) 3.53
Measuring the diaspora for virus-specific CD8+ T cells. Proc Natl Acad Sci U S A (2001) 3.51
Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartments. J Cell Biol (1993) 3.49
Seeing the herpesvirus capsid at 8.5 A. Science (2000) 3.35
Composite co-activator ARC mediates chromatin-directed transcriptional activation. Nature (1999) 3.32
Imaging human mesolimbic dopamine transmission with positron emission tomography: I. Accuracy and precision of D(2) receptor parameter measurements in ventral striatum. J Cereb Blood Flow Metab (2001) 3.31
Proton-pump inhibitors and risk of fractures: an update meta-analysis. Osteoporos Int (2016) 3.30
Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA (1997) 3.27
Efficacies of different preparations of glucosamine for the treatment of osteoarthritis: a meta-analysis of randomised, double-blind, placebo-controlled trials. Int J Clin Pract (2013) 3.16
Single-cell electroporation for gene transfer in vivo. Neuron (2001) 3.15
A chemokine receptor CCR2 allele delays HIV-1 disease progression and is associated with a CCR5 promoter mutation. Nat Med (1998) 3.15
Loss of P-glycoprotein expression in hematopoietic stem cells does not improve responses to imatinib in a murine model of chronic myelogenous leukemia. Leukemia (2005) 3.13
RAG mutations in human B cell-negative SCID. Science (1996) 3.03
Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterASIA). Diabetologia (2003) 3.00
Heat shock proteins transfer peptides during antigen processing and CTL priming. Immunogenetics (1994) 2.88
Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice. Proc Natl Acad Sci U S A (1999) 2.88
Effects of dog ownership in early childhood on immune development and atopic diseases. Clin Exp Allergy (2008) 2.86
Chimeric simian/human immunodeficiency virus that causes progressive loss of CD4+ T cells and AIDS in pig-tailed macaques. J Virol (1996) 2.86
Automated analysis of protein NMR assignments using methods from artificial intelligence. J Mol Biol (1997) 2.86
HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells. Leukemia (2010) 2.83
Structural and magnetic phase diagram of CeFeAsO(1- x)F(x) and its relation to high-temperature superconductivity. Nat Mater (2008) 2.83
CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. Proc Natl Acad Sci U S A (1999) 2.81
Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther (2001) 2.79
Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis. Immunity (2001) 2.77
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function. Proc Natl Acad Sci U S A (2001) 2.77
Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast. EMBO J (1998) 2.75
Physicochemical foundations and structural design of hydrogels in medicine and biology. Annu Rev Biomed Eng (2000) 2.73
Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region. Oncogene (2010) 2.73
Superconductivity at 41 K and its competition with spin-density-wave instability in layered CeO1-xFxFeAs. Phys Rev Lett (2008) 2.72
Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia. Clin Cancer Res (2000) 2.71
Familial expression of anti-Saccharomyces cerevisiae mannan antibodies in affected and unaffected relatives of patients with Crohn's disease. Gut (2000) 2.71
A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex. Mol Cell Biol (2000) 2.70
High-density lipoprotein cholesterol as a predictor of coronary heart disease risk. The PROCAM experience and pathophysiological implications for reverse cholesterol transport. Atherosclerosis (1996) 2.70
Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells. J Virol (2001) 2.69
Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci U S A (2001) 2.65
Changes in Friend murine erythroleukaemia cell membranes during induced differentiation determined by electrorotation. Biochim Biophys Acta (1994) 2.65