International Cancer Genome Consortium Data Portal--a one-stop shop for cancer genomics data.

PubWeight™: 4.53‹?› | Rank: Top 1%

🔗 View Article (PMC 3263593)

Published in Database (Oxford) on September 19, 2011

Authors

Junjun Zhang1, Joachim Baran, A Cros, Jonathan M Guberman, Syed Haider, Jack Hsu, Yong Liang, Elena Rivkin, Jianxin Wang, Brett Whitty, Marie Wong-Erasmus, Long Yao, Arek Kasprzyk

Author Affiliations

1: Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.

Articles citing this

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov (2012) 26.98

APOBEC3B is an enzymatic source of mutation in breast cancer. Nature (2013) 5.18

BioMart: driving a paradigm change in biological data management. Database (Oxford) (2011) 4.32

BioMart Central Portal: an open database network for the biological community. Database (Oxford) (2011) 3.03

Functional impact bias reveals cancer drivers. Nucleic Acids Res (2012) 2.96

BioMart: a data federation framework for large collaborative projects. Database (Oxford) (2011) 2.90

The BioMart community portal: an innovative alternative to large, centralized data repositories. Nucleic Acids Res (2015) 2.60

IntOGen-mutations identifies cancer drivers across tumor types. Nat Methods (2013) 2.10

Mining CK2 in cancer. PLoS One (2014) 1.87

3D Chromosome Regulatory Landscape of Human Pluripotent Cells. Cell Stem Cell (2015) 1.81

The Matchmaker Exchange: a platform for rare disease gene discovery. Hum Mutat (2015) 1.74

The Reactome BioMart. Database (Oxford) (2011) 1.66

CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer. Genome Biol (2015) 1.64

Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations. Nature (2017) 1.50

Molecular Heterogeneity of Ewing Sarcoma as Detected by Ion Torrent Sequencing. PLoS One (2016) 1.43

A self-updating road map of The Cancer Genome Atlas. Bioinformatics (2013) 1.38

Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation. Genome Med (2012) 1.32

Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas. Carcinogenesis (2012) 1.31

Building the foundation for genomics in precision medicine. Nature (2015) 1.28

A framework for organizing cancer-related variations from existing databases, publications and NGS data using a High-performance Integrated Virtual Environment (HIVE). Database (Oxford) (2014) 1.12

NCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomes. Database (Oxford) (2014) 1.10

BioXpress: an integrated RNA-seq-derived gene expression database for pan-cancer analysis. Database (Oxford) (2015) 0.97

Blocking and randomization to improve molecular biomarker discovery. Clin Cancer Res (2014) 0.96

BRONCO: Biomedical entity Relation ONcology COrpus for extracting gene-variant-disease-drug relations. Database (Oxford) (2016) 0.94

SomInaClust: detection of cancer genes based on somatic mutation patterns of inactivation and clustering. BMC Bioinformatics (2015) 0.93

Human genotype-phenotype databases: aims, challenges and opportunities. Nat Rev Genet (2015) 0.93

Generating a focused view of disease ontology cancer terms for pan-cancer data integration and analysis. Database (Oxford) (2015) 0.92

The pancreatic expression database: recent extensions and updates. Nucleic Acids Res (2013) 0.92

ARID1A alterations are associated with FGFR3-wild type, poor-prognosis, urothelial bladder tumors. PLoS One (2013) 0.91

OASIS: web-based platform for exploring cancer multi-omics data. Nat Methods (2015) 0.88

Next-generation sequencing: a powerful tool for the discovery of molecular markers in breast ductal carcinoma in situ. Expert Rev Mol Diagn (2013) 0.88

Omics Profiling in Precision Oncology. Mol Cell Proteomics (2016) 0.85

Computational methods and resources for the interpretation of genomic variants in cancer. BMC Genomics (2015) 0.85

Adaptive efficient compression of genomes. Algorithms Mol Biol (2012) 0.85

DIPSBC--data integration platform for systems biology collaborations. BMC Bioinformatics (2012) 0.84

A cloud-based workflow to quantify transcript-expression levels in public cancer compendia. Sci Rep (2016) 0.84

Molecular characterization of serous ovarian carcinoma using a multigene next generation sequencing cancer panel approach. BMC Res Notes (2014) 0.82

DoCM: a database of curated mutations in cancer. Nat Methods (2016) 0.81

Simultaneous inference of cancer pathways and tumor progression from cross-sectional mutation data. J Comput Biol (2015) 0.80

Identification of key regulators of pancreatic cancer progression through multidimensional systems-level analysis. Genome Med (2016) 0.80

Natural variation in the histone demethylase, KDM4C, influences expression levels of specific genes including those that affect cell growth. Genome Res (2013) 0.79

Immunoinformatics and epitope prediction in the age of genomic medicine. Genome Med (2015) 0.79

Oncogenomic portals for the visualization and analysis of genome-wide cancer data. Oncotarget (2016) 0.79

The search for cis-regulatory driver mutations in cancer genomes. Oncotarget (2015) 0.78

Toil enables reproducible, open source, big biomedical data analyses. Nat Biotechnol (2017) 0.77

Full-Length Enrich c-DNA Libraries-Clear Cell-Renal Cell Carcinoma. J Oncol (2012) 0.77

Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance. Oncotarget (2015) 0.77

Sharing and Reuse of Sensitive Data and Samples: Supporting Researchers in Identifying Ethical and Legal Requirements. Biopreserv Biobank (2015) 0.75

Identification of coding and non-coding mutational hotspots in cancer genomes. BMC Genomics (2017) 0.75

The International Serious Adverse Events Consortium's data sharing model. Nat Biotechnol (2013) 0.75

The ability of human nuclear DNA to cause false positive low-abundance heteroplasmy calls varies across the mitochondrial genome. BMC Genomics (2016) 0.75

BreCAN-DB: a repository cum browser of personalized DNA breakpoint profiles of cancer genomes. Nucleic Acids Res (2015) 0.75

Prediction of Genetic Interactions Using Machine Learning and Network Properties. Front Bioeng Biotechnol (2015) 0.75

Combinatorial Ranking of Gene Sets to Predict Disease Relapse: The Retinoic Acid Pathway in Early Prostate Cancer. Front Oncol (2017) 0.75

Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer. Oncotarget (2017) 0.75

Visual Display of 5p-arm and 3p-arm miRNA Expression with a Mobile Application. Biomed Res Int (2017) 0.75

Databases and tools for constructing signal transduction networks in cancer. BMB Rep (2017) 0.75

Sequence Factorization with Multiple References. PLoS One (2015) 0.75

On-Demand Indexing for Referential Compression of DNA Sequences. PLoS One (2015) 0.75

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma. Cancer Res (2016) 0.75

Population and clinical genetics of human transposable elements in the (post) genomic era. Mob Genet Elements (2017) 0.75

Systems biology of cancer: a challenging expedition for clinical and quantitative biologists. Front Bioeng Biotechnol (2014) 0.75

Human cancer databases (review). Oncol Rep (2014) 0.75

Simultaneous characterization of somatic events and HPV-18 integration in a metastatic cervical carcinoma patient using DNA and RNA sequencing. Int J Gynecol Cancer (2014) 0.75

MicroRNA profiling associated with non-small cell lung cancer: next generation sequencing detection, experimental validation, and prognostic value. Oncotarget (2017) 0.75

GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome. Gigascience (2017) 0.75

The CINSARC signature as a prognostic marker for clinical outcome in multiple neoplasms. Sci Rep (2017) 0.75

Resources for Interpreting Variants in Precision Genomic Oncology Applications. Front Oncol (2017) 0.75

Identification of a Novel Somatic Mutation Leading to Allele Dropout for EGFR L858R Genotyping in Non-Small Cell Lung Cancer. Mol Diagn Ther (2017) 0.75

Articles cited by this

KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res (2000) 117.00

Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature (2008) 75.40

The consensus coding sequences of human breast and colorectal cancers. Science (2006) 60.02

An integrated genomic analysis of human glioblastoma multiforme. Science (2008) 51.36

From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res (2006) 44.35

The genomic landscapes of human breast and colorectal cancers. Science (2007) 38.12

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science (2008) 36.02

Somatic mutations affect key pathways in lung adenocarcinoma. Nature (2008) 30.02

KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res (2009) 28.60

International network of cancer genome projects. Nature (2010) 20.35

BioMart Central Portal--unified access to biological data. Nucleic Acids Res (2009) 9.06

Ensembl BioMarts: a hub for data retrieval across taxonomic space. Database (Oxford) (2011) 6.04

BioMart Central Portal: an open database network for the biological community. Database (Oxford) (2011) 3.03

BioMart: a data federation framework for large collaborative projects. Database (Oxford) (2011) 2.90

Data mining using the Catalogue of Somatic Mutations in Cancer BioMart. Database (Oxford) (2011) 2.84

The Reactome BioMart. Database (Oxford) (2011) 1.66

Using BioMart as a framework to manage and query pancreatic cancer data. Database (Oxford) (2011) 1.43

BCCTBbp: the Breast Cancer Campaign Tissue Bank bioinformatics portal. Nucleic Acids Res (2014) 1.05

Articles by these authors

The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36

International network of cancer genome projects. Nature (2010) 20.35

BioMart--biological queries made easy. BMC Genomics (2009) 11.06

Ensembl's 10th year. Nucleic Acids Res (2009) 10.82

An overview of Ensembl. Genome Res (2004) 10.35

BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis. Bioinformatics (2005) 9.84

BioMart Central Portal--unified access to biological data. Nucleic Acids Res (2009) 9.06

Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol (2004) 7.17

Ensembl BioMarts: a hub for data retrieval across taxonomic space. Database (Oxford) (2011) 6.04

BioMart: driving a paradigm change in biological data management. Database (Oxford) (2011) 4.32

Human genomic deletions mediated by recombination between Alu elements. Am J Hum Genet (2006) 3.15

BioMart Central Portal: an open database network for the biological community. Database (Oxford) (2011) 3.03

BioMart: a data federation framework for large collaborative projects. Database (Oxford) (2011) 2.90

Ergatis: a web interface and scalable software system for bioinformatics workflows. Bioinformatics (2010) 2.69

Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome. Blood (2002) 2.50

WormBase 2014: new views of curated biology. Nucleic Acids Res (2013) 2.39

Corelease of dopamine and serotonin from striatal dopamine terminals. Neuron (2005) 2.36

Quantitative genome-scale analysis of protein localization in an asymmetric bacterium. Proc Natl Acad Sci U S A (2009) 2.33

A heterozygous moth genome provides insights into herbivory and detoxification. Nat Genet (2013) 2.13

SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer. J Pathol (2013) 1.87

Alu retrotransposition-mediated deletion. J Mol Biol (2005) 1.79

Proteomic fingerprints for potential application to early diagnosis of severe acute respiratory syndrome. Clin Chem (2004) 1.76

Genomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineages. Nucleic Acids Res (2005) 1.73

The Semanticscience Integrated Ontology (SIO) for biomedical research and knowledge discovery. J Biomed Semantics (2014) 1.66

Transcriptional profiling implicates novel interactions between abiotic stress and hormonal responses in Thellungiella, a close relative of Arabidopsis. Plant Physiol (2006) 1.62

Alu recombination-mediated structural deletions in the chimpanzee genome. PLoS Genet (2007) 1.59

Intra- and inter-chromosomal interactions correlate with CTCF binding genome wide. Mol Syst Biol (2010) 1.59

Dopamine signaling differences in the nucleus accumbens and dorsal striatum exploited by nicotine. J Neurosci (2009) 1.58

Caulobacter chromosome segregation is an ordered multistep process. Proc Natl Acad Sci U S A (2010) 1.55

The 3rd DBCLS BioHackathon: improving life science data integration with Semantic Web technologies. J Biomed Semantics (2013) 1.44

Distinct epigenomic features in end-stage failing human hearts. Circulation (2011) 1.39

Nicotinic cholinergic synaptic mechanisms in the ventral tegmental area contribute to nicotine addiction. Learn Mem (2004) 1.38

Polyethylene glycol modified, cross-linked starch-coated iron oxide nanoparticles for enhanced magnetic tumor targeting. Biomaterials (2010) 1.33

An unexpected role of a trace amount of water in catalyzing proton transfer in phosphine-catalyzed (3 + 2) cycloaddition of allenoates and alkenes. J Am Chem Soc (2007) 1.28

Different evolutionary fates of recently integrated human and chimpanzee LINE-1 retrotransposons. Gene (2006) 1.26

Identification and characterization of novel polymorphic LINE-1 insertions through comparison of two human genome sequence assemblies. Gene (2006) 1.24

EpiChIP: gene-by-gene quantification of epigenetic modification levels. Nucleic Acids Res (2010) 1.23

Molecular epidemiology of measles viruses in China, 1995-2003. Virol J (2007) 1.20

A comparison of the functional modules identified from time course and static PPI network data. BMC Bioinformatics (2011) 1.20

The Fugu tyrp1 promoter directs specific GFP expression in zebrafish: tools to study the RPE and the neural crest-derived melanophores. Pigment Cell Res (2006) 1.17

Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway. Mol Cell Biochem (2012) 1.13

BioHackathon series in 2011 and 2012: penetration of ontology and linked data in life science domains. J Biomed Semantics (2014) 1.12

Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data. BMC Bioinformatics (2012) 1.10

Live neuron morphology automatically reconstructed from multiphoton and confocal imaging data. J Neurophysiol (2008) 1.09

[The response to environmental pH of RIM101 pathway in Candida albicans]. Wei Sheng Wu Xue Bao (2007) 1.09

A SNP map of the rat genome generated from cDNA sequences. Science (2004) 1.06

Rubella virus genotypes in the People's Republic of China between 1979 and 2007: a shift in endemic viruses during the 2001 Rubella Epidemic. J Clin Microbiol (2010) 1.06

A comparison of the aging and apoptotic transcriptome of Saccharomyces cerevisiae. FEMS Yeast Res (2005) 1.05

Computational purification of individual tumor gene expression profiles leads to significant improvements in prognostic prediction. Genome Med (2013) 1.05

Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles. Biomaterials (2011) 1.05

Preparation and characterization of a novel electrospun spider silk fibroin/poly(D,L-lactide) composite fiber. J Phys Chem B (2008) 1.04

Hematopoietic stem cell transplantation: an overview of infection risks and epidemiology. Infect Dis Clin North Am (2010) 1.04

Isomeric cyclopropenes exhibit unique bioorthogonal reactivities. J Am Chem Soc (2013) 1.03

Complete genome sequence of Bacillus amyloliquefaciens TA208, a strain for industrial production of guanosine and ribavirin. J Bacteriol (2011) 1.02

Hydroxyl ion addition to one-electron oxidized thymine: unimolecular interconversion of C5 to C6 OH-adducts. J Am Chem Soc (2013) 1.02

MicroRNA-21 knockout improve the survival rate in DSS induced fatal colitis through protecting against inflammation and tissue injury. PLoS One (2013) 1.02

Metal-free oxidation of aromatic carbon-hydrogen bonds through a reverse-rebound mechanism. Nature (2013) 1.01

Iteration method for predicting essential proteins based on orthology and protein-protein interaction networks. BMC Syst Biol (2012) 1.01

Visual display terminal use increases the prevalence and risk of work-related musculoskeletal disorders among Chinese office workers: a cross-sectional study. J Occup Health (2011) 1.00

Epigenetic markers of prostate cancer in plasma circulating DNA. Hum Mol Genet (2012) 0.99

Management of respiratory compromise caused by cervical osteophytes: a case report and review of the literature. Spine J (2003) 0.99

The 2nd DBCLS BioHackathon: interoperable bioinformatics Web services for integrated applications. J Biomed Semantics (2011) 0.99

Osteoblast function on electrically conductive electrospun PLA/MWCNTs nanofibers. Biomaterials (2011) 0.99

Mechanistic twist of the [8+2] cycloadditions of dienylisobenzofurans and dimethyl acetylenedicarboxylate: stepwise [8+2] versus [4+2]/[1,5]-vinyl shift mechanisms revealed through a theoretical and experimental study. J Am Chem Soc (2007) 0.98

Curb challenges of the "Trojan Horse" approach: smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery. Adv Drug Deliv Rev (2013) 0.97

Predicting Essential Proteins Based on Weighted Degree Centrality. IEEE/ACM Trans Comput Biol Bioinform (2015) 0.97

A computationally designed Rh(I)-catalyzed two-component [5+2+1] cycloaddition of ene-vinylcyclopropanes and CO for the synthesis of cyclooctenones. J Am Chem Soc (2007) 0.96

Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase RhoB. Biochem Biophys Res Commun (2013) 0.96

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium. J Enzyme Inhib Med Chem (2014) 0.96

Measles resurgence associated with continued circulation of genotype H1 viruses in China, 2005. Virol J (2009) 0.96

Detecting Protein Complexes Based on Uncertain Graph Model. IEEE/ACM Trans Comput Biol Bioinform (2015) 0.96

Diagnosis of multiple primary lung cancer: a systematic review. J Int Med Res (2013) 0.96

A mimicking-of-DNA-methylation-patterns pipeline for overcoming the restriction barrier of bacteria. PLoS Genet (2012) 0.96

Malignant parotid tumors: presentation, clinical/pathologic prognostic factors, and treatment outcomes. Int J Radiat Oncol Biol Phys (2005) 0.95

The landscape of DNA repeat elements in human heart failure. Genome Biol (2012) 0.95

Diels-Alder reactivities of strained and unstrained cycloalkenes with normal and inverse-electron-demand dienes: activation barriers and distortion/interaction analysis. J Am Chem Soc (2013) 0.95

A genetic screen for mutations that affect cranial nerve development in the mouse. J Neurosci (2005) 0.95

A local average connectivity-based method for identifying essential proteins from the network level. Comput Biol Chem (2011) 0.94

Alkaline stress triggers an immediate calcium fluctuation in Candida albicans mediated by Rim101p and Crz1p transcription factors. FEMS Yeast Res (2011) 0.94