Published in Nat Methods on September 15, 2013
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The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types. Oncotarget (2017) 0.80
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Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance. Oncotarget (2015) 0.77
Multi-omics analysis of primary glioblastoma cell lines shows recapitulation of pivotal molecular features of parental tumors. Neuro Oncol (2017) 0.77
Reprogramming strategies for the establishment of novel human cancer models. Cell Cycle (2016) 0.77
Discovery of Cancer Driver Long Noncoding RNAs across 1112 Tumour Genomes: New Candidates and Distinguishing Features. Sci Rep (2017) 0.76
Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis. Cell Syst (2016) 0.76
Deregulation of Rho GTPases in cancer. Small GTPases (2016) 0.76
Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma. Cancer Discov (2017) 0.75
Altered oncomodules underlie chromatin regulatory factors driver mutations. Oncotarget (2016) 0.75
Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes. Front Genet (2017) 0.75
Impact of germline and somatic missense variations on drug binding sites. Pharmacogenomics J (2016) 0.75
Emerging role of mutations in epigenetic regulators including MLL2 derived from The Cancer Genome Atlas for cervical cancer. BMC Cancer (2017) 0.75
Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types. Genome Med (2016) 0.75
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Exome Sequencing of Oral Squamous Cell Carcinoma Reveals Molecular Subgroups and Novel Therapeutic Opportunities. Theranostics (2017) 0.75
CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma. Cancer Res (2016) 0.75
Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease. Wiley Interdiscip Rev RNA (2015) 0.75
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High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival. Int J Cancer (2017) 0.75
Practical aspects of NGS-based pathways analysis for personalized cancer science and medicine. Oncotarget (2016) 0.75
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Computational approaches for the identification of cancer genes and pathways. Wiley Interdiscip Rev Syst Biol Med (2016) 0.75
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The whole-genome landscape of medulloblastoma subtypes. Nature (2017) 0.75
NetNorM: Capturing cancer-relevant information in somatic exome mutation data with gene networks for cancer stratification and prognosis. PLoS Comput Biol (2017) 0.75
Comparison of algorithms for the detection of cancer drivers at subgene resolution. Nat Methods (2017) 0.75
A PanorOmic view of personal cancer genomes. Nucleic Acids Res (2017) 0.75
Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases. Oral Oncol (2017) 0.75
Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers. Oncotarget (2017) 0.75
Molecular Characterization of Somatic Alterations in Dukes' B and C Colorectal Cancers by Targeted Sequencing. Front Pharmacol (2017) 0.75
Resources for Interpreting Variants in Precision Genomic Oncology Applications. Front Oncol (2017) 0.75
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Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc (2009) 38.62
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Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature (2012) 8.03
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet (2011) 6.43
Personalized oncology through integrative high-throughput sequencing: a pilot study. Sci Transl Med (2011) 5.82
Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82
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IntOGen: integration and data mining of multidimensional oncogenomic data. Nat Methods (2010) 3.63
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Functional impact bias reveals cancer drivers. Nucleic Acids Res (2012) 2.96
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OncodriveCLUST: exploiting the positional clustering of somatic mutations to identify cancer genes. Bioinformatics (2013) 1.90
Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation. Genome Med (2012) 1.32
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IntOGen: integration and data mining of multidimensional oncogenomic data. Nat Methods (2010) 3.63
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SNP and haplotype mapping for genetic analysis in the rat. Nat Genet (2008) 2.96
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Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes. Nucleic Acids Res (2006) 1.95
OncodriveCLUST: exploiting the positional clustering of somatic mutations to identify cancer genes. Bioinformatics (2013) 1.90
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Gender differences in clinical manifestations of Brugada syndrome. J Am Coll Cardiol (2008) 1.67
Computational approaches to identify functional genetic variants in cancer genomes. Nat Methods (2013) 1.64
Preparation for pacemaker or implantable cardiac defibrillator implants in patients with high risk of thrombo-embolic events: oral anticoagulation or bridging with intravenous heparin? A prospective randomized trial. Eur Heart J (2009) 1.63
Low efficacy of atrial fibrillation ablation in severe obstructive sleep apnoea patients. Europace (2010) 1.61
Survival in New York Heart Association class IV heart failure patients treated with cardiac resynchronization therapy compared with patients on optimal pharmacological treatment. Europace (2010) 1.55
Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia. Genome Res (2013) 1.51
Efficacy of circumferential pulmonary vein ablation of atrial fibrillation in endurance athletes. Europace (2010) 1.50
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Electrocardiographic optimization of interventricular delay in cardiac resynchronization therapy: a simple method to optimize the device. J Cardiovasc Electrophysiol (2007) 1.47
Transcriptional activation of polycomb-repressed genes by ZRF1. Nature (2010) 1.44
Six-minute walking test predicts long-term cardiac death in patients who received cardiac resynchronization therapy. Europace (2009) 1.44
PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis. Bioinformatics (2012) 1.43
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Oncodrive-CIS: a method to reveal likely driver genes based on the impact of their copy number changes on expression. PLoS One (2013) 0.97
Optimizing the programation of cardiac resynchronization therapy devices in patients with heart failure and left bundle branch block. Am J Cardiol (2007) 0.97
Sample-level enrichment analysis unravels shared stress phenotypes among multiple cancer types. Genome Med (2012) 0.96
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Effect of repeated radiofrequency catheter ablation on left atrial function for the treatment of atrial fibrillation. Am J Cardiol (2011) 0.93
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Expression of polycomb targets predicts breast cancer prognosis. Mol Cell Biol (2013) 0.88
Usefulness of ventricular dyssynchrony measured using M-mode echocardiography to predict response to resynchronization therapy. Am J Cardiol (2007) 0.86
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Left atrial contractility is preserved after successful circumferential pulmonary vein ablation in patients with atrial fibrillation. J Cardiovasc Electrophysiol (2008) 0.85
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