Kai Kaarniranta

Author PubWeight™ 122.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan. J Mol Med (Berl) 2011 2.26
3 Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev 2007 1.96
4 Regulation of the aging process by autophagy. Trends Mol Med 2009 1.69
5 Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders. Cell Signal 2013 1.65
6 Inflammaging: disturbed interplay between autophagy and inflammasomes. Aging (Albany NY) 2012 1.58
7 Inflammation in Alzheimer's disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors. Prog Neurobiol 2009 1.57
8 AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network. Ageing Res Rev 2011 1.53
9 ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology. J Neuroinflammation 2009 1.46
10 Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells--implications for age-related macular degeneration (AMD). Immunol Lett 2012 1.46
11 Celastrol: Molecular targets of Thunder God Vine. Biochem Biophys Res Commun 2010 1.45
12 Maturation of autophagosomes and endosomes: a key role for Rab7. Biochim Biophys Acta 2012 1.43
13 Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP). Cell Signal 2011 1.41
14 Pharmacokinetics, efficacy and safety profiles of preserved and preservative-free tafluprost in healthy volunteers. Acta Ophthalmol Suppl (Oxf ) 2008 1.39
15 Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-kappaB signaling. Cell Signal 2009 1.34
16 Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration. Acta Ophthalmol 2011 1.31
17 SIRT1: regulation of longevity via autophagy. Cell Signal 2009 1.29
18 Switching from a preserved to a preservative-free prostaglandin preparation in topical glaucoma medication. Acta Ophthalmol 2010 1.29
19 Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype. Eur J Neurosci 2011 1.26
20 Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization. Mol Med 2010 1.22
21 Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells. PLoS One 2013 1.20
22 Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma. Graefes Arch Clin Exp Ophthalmol 2006 1.19
23 Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases. Cell Mol Life Sci 2012 1.19
24 Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90. Immunol Lett 2008 1.18
25 SIRT1 longevity factor suppresses NF-kappaB -driven immune responses: regulation of aging via NF-kappaB acetylation? Bioessays 2008 1.17
26 AMP-activated protein kinase: a potential player in Alzheimer's disease. J Neurochem 2011 1.16
27 Regulatory role of HIF-1alpha in the pathogenesis of age-related macular degeneration (AMD). Ageing Res Rev 2009 1.16
28 Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology. J Cell Mol Med 2008 1.16
29 Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells. J Cell Mol Med 2008 1.14
30 Mitochondrial and nuclear DNA damage and repair in age-related macular degeneration. Int J Mol Sci 2013 1.13
31 Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome. Prog Neurobiol 2013 1.12
32 Control of p53 and NF-κB signaling by WIP1 and MIF: role in cellular senescence and organismal aging. Cell Signal 2010 1.11
33 NF-kappaB signaling in the aging process. J Clin Immunol 2009 1.10
34 Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process. Int J Mol Sci 2013 1.07
35 cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressure. Biochim Biophys Acta 2002 1.06
36 ER stress and hormetic regulation of the aging process. Ageing Res Rev 2010 1.04
37 Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish population. Mol Vis 2006 1.04
38 Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: impact on the aging process. Ageing Res Rev 2012 1.03
39 Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration. PLoS One 2008 1.03
40 Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease. Prog Neurobiol 2011 1.02
41 Comparison of three intraocular pressure measurement methods including biomechanical properties of the cornea. Invest Ophthalmol Vis Sci 2014 1.01
42 Apoptosis and aging: increased resistance to apoptosis enhances the aging process. Cell Mol Life Sci 2010 1.01
43 Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease. Prog Neurobiol 2010 0.99
44 Efflux protein expression in human retinal pigment epithelium cell lines. Pharm Res 2009 0.97
45 Symptom score questionnaire for nasolacrimal duct obstruction in adults--a novel tool to assess the outcome after endoscopic dacryocystorhinostomy. Rhinology 2010 0.97
46 p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells. Mol Vis 2010 0.95
47 Retinal arterial macroaneurysms. Acta Ophthalmol 2013 0.95
48 Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells. Biochem Biophys Res Commun 2007 0.93
49 Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD). Biogerontology 2013 0.92
50 A prospective study on postoperative pain after cataract surgery. Clin Ophthalmol 2013 0.90
51 Siglec receptors and hiding plaques in Alzheimer's disease. J Mol Med (Berl) 2009 0.90
52 Glycolysis links p53 function with NF-kappaB signaling: impact on cancer and aging process. J Cell Physiol 2010 0.90
53 Structure and barrier properties of human embryonic stem cell-derived retinal pigment epithelial cells are affected by extracellular matrix protein coating. Tissue Eng Part A 2014 0.90
54 Cellular and molecular mechanisms of age-related macular degeneration: from impaired autophagy to neovascularization. Int J Biochem Cell Biol 2013 0.89
55 The effect of 17beta-estradiol on IL-6 secretion and NF-kappaB DNA-binding activity in human retinal pigment epithelial cells. Immunol Lett 2007 0.89
56 The preservative polyquaternium-1 increases cytoxicity and NF-kappaB linked inflammation in human corneal epithelial cells. Mol Vis 2012 0.88
57 Regression of necrotizing scleritis in Wegener's granulomatosis after infliximab treatment. Acta Ophthalmol 2009 0.88
58 Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells. Eur J Pharmacol 2008 0.88
59 Immunolocalization of EMMPRIN (CD147) in the human eye and detection of soluble form of EMMPRIN in ocular fluids. Curr Eye Res 2006 0.87
60 Alpha-lipoic Acid modulates heat shock factor-1 expression in streptozotocin-induced diabetic rat kidney. Antioxid Redox Signal 2007 0.87
61 Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process. Int J Cell Biol 2012 0.87
62 Phospholipase A2 in chamber angle of normal eyes and patients with primary open angle glaucoma and exfoliation glaucoma. Mol Vis 2007 0.86
63 Postoperative pain after cataract surgery. J Cataract Refract Surg 2013 0.85
64 Imiquimod in the treatment of eyelid basal cell carcinoma. Acta Ophthalmol Scand 2007 0.85
65 ROCK, PAK, and Toll of synapses in Alzheimer's disease. Biochem Biophys Res Commun 2008 0.85
66 Strong expression of HSP47 in metaplastic nasal mucosa may predict a poor outcome after primary endoscopic dacryocystorhinostomy: a prospective study. Acta Ophthalmol 2011 0.85
67 Celastrol regulates innate immunity response via NF-κB and Hsp70 in human retinal pigment epithelial cells. Pharmacol Res 2011 0.85
68 Autophagy--hot topic in AMD. Acta Ophthalmol 2010 0.84
69 Protein-oxidized phospholipid interactions in cellular signaling for cell death: from biophysics to clinical correlations. Biochim Biophys Acta 2012 0.84
70 Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process. J Mol Med (Berl) 2014 0.84
71 Hydrostatic pressure-induced changes in cellular protein synthesis. Biorheology 2004 0.84
72 Gene expression profiles in chondrosarcoma cells subjected to cyclic stretching and hydrostatic pressure. A cDNA array study. Biorheology 2003 0.83
73 Filter-cultured ARPE-19 cells as outer blood-retinal barrier model. Eur J Pharm Sci 2010 0.83
74 Genetics vs. entropy: longevity factors suppress the NF-kappaB-driven entropic aging process. Ageing Res Rev 2009 0.83
75 Phytochemicals suppress nuclear factor-κB signaling: impact on health span and the aging process. Curr Opin Clin Nutr Metab Care 2012 0.83
76 Genetic variability in DNA repair proteins in age-related macular degeneration. Int J Mol Sci 2012 0.83
77 NEMO shuttle: a link between DNA damage and NF-kappaB activation in progeroid syndromes? Biochem Biophys Res Commun 2008 0.82
78 SIRT1 regulates the ribosomal DNA locus: epigenetic candles twinkle longevity in the Christmas tree. Biochem Biophys Res Commun 2008 0.82
79 Cis-urocanic acid inhibits SAPK/JNK signaling pathway in UV-B exposed human corneal epithelial cells in vitro. Mol Vis 2011 0.82
80 ADAMTS9 locus associates with increased risk of wet AMD. Acta Ophthalmol 2014 0.81
81 5'-Adenosine monophosphate-activated protein kinase--mammalian target of rapamycin axis as therapeutic target for age-related macular degeneration. Rejuvenation Res 2011 0.81
82 Corneal epithelium as a platform for secretion of transgene products after transfection with liposomal gene eyedrops. J Gene Med 2007 0.80
83 Altered calcium signaling in an experimental model of glaucoma. Invest Ophthalmol Vis Sci 2010 0.80
84 Mitomycin C in revision endoscopic dacryocystorhinostomy: a prospective randomized study. Am J Rhinol Allergy 2011 0.80
85 Epigenetic regulation of ASC/TMS1 expression: potential role in apoptosis and inflammasome function. Cell Mol Life Sci 2013 0.79
86 Efflux protein expression in human stem cell-derived retinal pigment epithelial cells. PLoS One 2012 0.79
87 Influence of selective estrogen receptor modulators on interleukin-6 expression in human retinal pigment epithelial cells (ARPE-19). Eur J Pharmacol 2010 0.79
88 Potential of epigenetic mechanisms in AMD pathology. Front Biosci (Schol Ed) 2013 0.79
89 Histopathology of the three implanted degradable biopolymers in rabbit eye. J Biomed Mater Res A 2009 0.79
90 Increased IL-6 levels are not related to NF-κB or HIF-1α transcription factors activity in the vitreous of proliferative diabetic retinopathy. J Diabetes Complications 2011 0.79
91 Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice. Mol Vis 2012 0.78
92 Hsp90 inhibitor geldanamycin increases hsp70 mRNA stabilisation but fails to activate HSF1 in cells exposed to hydrostatic pressure. Biochim Biophys Acta 2005 0.78
93 Regulation of ER alpha signaling pathway in neuronal HN10 cells: role of protein acetylation and Hsp90. Neurochem Res 2008 0.78
94 Visual recovery of the amblyopic eye in an adult patient after loss of the dominant eye. Acta Ophthalmol Scand 2003 0.78
95 High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis. Biorheology 2002 0.77
96 Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies. Mol Vis 2012 0.77
97 Hypoxic conditions stimulate the release of B-type natriuretic peptide from human retinal pigment epithelium cell culture. Acta Ophthalmol 2014 0.77
98 Recovery and patient satisfaction after cataract surgery. A one-year prospective follow-up study. Acta Ophthalmol 2014 0.76
99 Oxidative stress protection by exogenous delivery of rhHsp70 chaperone to the retinal pigment epithelium (RPE), a possible therapeutic strategy against RPE degeneration. Pharm Res 2014 0.76
100 In vitro biocompatibility of degradable biopolymers in cell line cultures from various ocular tissues: extraction studies. J Mater Sci Mater Med 2007 0.76
101 Specific induction of heat shock protein 90beta by high hydrostatic pressure. Biorheology 2003 0.76
102 Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration. Mol Vis 2009 0.76
103 Changes in neurophysiologic markers of visual processing following beneficial anti-VEGF treatment in macular degeneration. Clin Ophthalmol 2013 0.75
104 Influence of Hsp90 and HDAC inhibition and tubulin acetylation on perinuclear protein aggregation in human retinal pigment epithelial cells. J Biomed Biotechnol 2010 0.75
105 Endoscopic dacryocystorhinostomy as treatment for lower lacrimal pathway obstructions in adults: Review article. Allergy Rhinol (Providence) 2015 0.75
106 Retinal haemorrhages in shaken baby syndrome. Acta Ophthalmol 2008 0.75
107 [Not Available]. Duodecim 2007 0.75
108 Maculopathy in Pierre Robin sequences. J Pediatr Ophthalmol Strabismus 2007 0.75
109 [Surgery for lower nasolacrimal duct obstructions in adults]. Duodecim 2012 0.75
110 Herpes simplex virus types 1 and 2 modulate autophagy in SIRC corneal cells. J Biosci 2014 0.75
111 Relation of biometric eye profile with intraocular pressure corrections in healthy myopes. Acta Ophthalmol 2012 0.75
112 Biocompatibility of different poly(lactide-coglycolide) polymers implanted into the subconjunctival space in rats. Ophthalmic Res 2011 0.75