Philipp Khaitovich

Author PubWeight™ 77.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intra- and interspecific variation in primate gene expression patterns. Science 2002 7.92
2 The evolution of gene expression levels in mammalian organs. Nature 2011 7.16
3 A genome-wide comparison of recent chimpanzee and human segmental duplications. Nature 2005 5.51
4 Fast mapping of short sequences with mismatches, insertions and deletions using index structures. PLoS Comput Biol 2009 4.24
5 Estimating accuracy of RNA-Seq and microarrays with proteomics. BMC Genomics 2009 3.87
6 MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain. Genome Res 2010 2.44
7 FUNC: a package for detecting significant associations between gene sets and ontological annotations. BMC Bioinformatics 2007 2.32
8 Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway. Cell Metab 2011 2.22
9 Lineage-specific expansions of retroviral insertions within the genomes of African great apes but not humans and orangutans. PLoS Biol 2005 1.82
10 Transcriptional neoteny in the human brain. Proc Natl Acad Sci U S A 2009 1.78
11 Aging and gene expression in the primate brain. PLoS Biol 2005 1.76
12 Sequence features associated with microRNA strand selection in humans and flies. BMC Genomics 2009 1.76
13 Birth and expression evolution of mammalian microRNA genes. Genome Res 2012 1.64
14 Comprehensive survey of human brain microRNA by deep sequencing. BMC Genomics 2010 1.59
15 MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates. PLoS Biol 2011 1.57
16 Widespread expression of piRNA-like molecules in somatic tissues. Nucleic Acids Res 2011 1.56
17 Evidence for human microRNA-offset RNAs in small RNA sequencing data. Bioinformatics 2009 1.55
18 Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron 2008 1.54
19 Comparison of protein and mRNA expression evolution in humans and chimpanzees. PLoS One 2007 1.42
20 MicroRNA expression and regulation in human, chimpanzee, and macaque brains. PLoS Genet 2011 1.40
21 Human and chimpanzee gene expression differences replicated in mice fed different diets. PLoS One 2008 1.35
22 Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq. PLoS Comput Biol 2010 1.33
23 Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques. Genome Res 2012 1.27
24 Human brain evolution. Prog Brain Res 2006 1.26
25 Widespread splicing changes in human brain development and aging. Mol Syst Biol 2013 1.23
26 Gene expression becomes heterogeneous with age. Curr Biol 2006 1.18
27 Human brain evolution: transcripts, metabolites and their regulators. Nat Rev Neurosci 2013 1.16
28 Positive selection on gene expression in the human brain. Curr Biol 2006 1.14
29 Rapid metabolic evolution in human prefrontal cortex. Proc Natl Acad Sci U S A 2011 1.09
30 Evolution of the human-specific microRNA miR-941. Nat Commun 2012 1.06
31 Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel. Physiol Genomics 2010 0.98
32 Systematic analysis of gene expression in human brains before and after death. Genome Biol 2005 0.98
33 Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development. Am J Hum Genet 2008 0.93
34 Ab initio identification of transcription start sites in the Rhesus macaque genome by histone modification and RNA-Seq. Nucleic Acids Res 2010 0.90
35 Functional analysis of human and chimpanzee promoters. Genome Biol 2005 0.89
36 Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging. Genome Biol 2015 0.89
37 Stress-associated H3K4 methylation accumulates during postnatal development and aging of rhesus macaque brain. Aging Cell 2012 0.87
38 The effects of probe binding affinity differences on gene expression measurements and how to deal with them. Bioinformatics 2009 0.86
39 Evolution of neuronal and endothelial transcriptomes in primates. Genome Biol Evol 2010 0.85
40 Evolutionary and ontogenetic changes in RNA editing in human, chimpanzee, and macaque brains. RNA 2013 0.83
41 Development and application of a modified dynamic time warping algorithm (DTW-S) to analyses of primate brain expression time series. BMC Bioinformatics 2011 0.82
42 Spatial proximity and similarity of the epigenetic state of genome domains. PLoS One 2012 0.82
43 Deep sequencing reveals a novel class of bidirectional promoters associated with neuronal genes. BMC Genomics 2014 0.81
44 Accelerated aging-related transcriptome changes in the female prefrontal cortex. Aging Cell 2012 0.76
45 Mechanisms of dietary response in mice and primates: a role for EGR1 in regulating the reaction to human-specific nutritional content. PLoS One 2012 0.75