Published in Nucleic Acids Res on October 14, 2010
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Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci U S A (2008) 5.94
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Global diversity in the human salivary microbiome. Genome Res (2009) 5.16
Metabolite identification via the Madison Metabolomics Consortium Database. Nat Biotechnol (2008) 5.12
Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat Genet (2007) 4.69
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA. Cell Res (2011) 4.55
Generation of induced pluripotent stem cell lines from adult rat cells. Cell Stem Cell (2008) 4.52
Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human. Nat Methods (2009) 4.38
Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation. Cell (2010) 4.28
Fast mapping of short sequences with mismatches, insertions and deletions using index structures. PLoS Comput Biol (2009) 4.24
Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila. Science (2009) 4.13
IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J Clin Invest (2008) 4.12
Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in China. Ann Neurol (2011) 4.09
Modification of kidney barrier function by the urokinase receptor. Nat Med (2007) 4.01
Estimating accuracy of RNA-Seq and microarrays with proteomics. BMC Genomics (2009) 3.87
Exchange-coupled nanocomposite magnets by nanoparticle self-assembly. Nature (2002) 3.71
Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Nature (2005) 3.62
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature (2007) 3.55
Patient navigation and case management following an abnormal mammogram: a randomized clinical trial. Prev Med (2006) 3.45
Neuronal activity modifies the DNA methylation landscape in the adult brain. Nat Neurosci (2011) 3.27
Mental health system in China: history, recent service reform and future challenges. World Psychiatry (2011) 3.23
Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis. Sci Transl Med (2011) 3.19
Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science (2013) 3.17
Prediction of adverse maternal outcomes in pre-eclampsia: development and validation of the fullPIERS model. Lancet (2010) 3.15
The transcription unit architecture of the Escherichia coli genome. Nat Biotechnol (2009) 2.85
Circulating suPAR in two cohorts of primary FSGS. J Am Soc Nephrol (2012) 2.83
Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression. Cell (2013) 2.81
A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells. PLoS Genet (2009) 2.78
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Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients. J Infect Dis (2012) 2.53
Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue. Proc Natl Acad Sci U S A (2003) 2.50
Randomized controlled trial of collaborative care management of depression among low-income patients with cancer. J Clin Oncol (2008) 2.47
Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of hepatic gluconeogenesis in the intact mouse liver. Cell Metab (2007) 2.47
MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain. Genome Res (2010) 2.44
MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4. Blood (2007) 2.40
Multiplex padlock targeted sequencing reveals human hypermutable CpG variations. Genome Res (2009) 2.38
N-Benzyl-2-(2,6-dichloro-phen-oxy)-acetamide. Acta Crystallogr Sect E Struct Rep Online (2008) 2.36
Next-generation digital information storage in DNA. Science (2012) 2.33
FUNC: a package for detecting significant associations between gene sets and ontological annotations. BMC Bioinformatics (2007) 2.32
Induction of TRPC6 channel in acquired forms of proteinuric kidney disease. J Am Soc Nephrol (2006) 2.32
The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis. Cell (2012) 2.30
Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors. Cell Res (2008) 2.29
Control of the pattern-recognition receptor EFR by an ER protein complex in plant immunity. EMBO J (2009) 2.28
Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway. Cell Metab (2011) 2.22
Growth of graphene from solid carbon sources. Nature (2010) 2.21
Chronic stimulation of Nod2 mediates tolerance to bacterial products. Proc Natl Acad Sci U S A (2007) 2.20
Project management system for structural and functional proteomics: Sesame. J Struct Funct Genomics (2003) 2.19
New bioinformatics resources for metabolomics. Pac Symp Biocomput (2007) 2.19
Regulation of human airway epithelial cell IL-8 expression by MAP kinases. Am J Physiol Lung Cell Mol Physiol (2002) 2.19
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. Blood (2010) 2.15
A paired-end sequencing strategy to map the complex landscape of transcription initiation. Nat Methods (2010) 2.14
Effects of vacuum-assisted closure on wound microcirculation: an experimental study. Asian J Surg (2005) 2.14
A sphingosine-1-phosphate-activated calcium channel controlling vascular smooth muscle cell motility. Circ Res (2006) 2.12
Generation of functional ion-channel tools by E3 targeting. Nat Biotechnol (2005) 2.08
The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model. Exp Diabetes Res (2009) 2.08
Regulation of CXCR4 expression in human mesenchymal stem cells by cytokine treatment: role in homing efficiency in NOD/SCID mice. Haematologica (2007) 2.07
Whole-genome resequencing of Escherichia coli K-12 MG1655 undergoing short-term laboratory evolution in lactate minimal media reveals flexible selection of adaptive mutations. Genome Biol (2009) 2.06
Reducing personal exposure to particulate air pollution improves cardiovascular health in patients with coronary heart disease. Environ Health Perspect (2012) 2.05
Learning brain connectivity of Alzheimer's disease by sparse inverse covariance estimation. Neuroimage (2010) 2.04
A phosphorylation state-specific antibody recognizes Hsp27, a novel substrate of protein kinase D. J Biol Chem (2005) 2.03
Synthesis and functional analyses of nuclear clusterin, a cell death protein. J Biol Chem (2003) 2.01
Expression of midkine and endoglin in breast carcinomas with different immunohistochemical profiles. APMIS (2010) 2.00
Genetic variation in selenoprotein S influences inflammatory response. Nat Genet (2005) 2.00
Effect of otitis media with effusion and its clinical intervention on the development of mastoid in children. Acta Otolaryngol (2014) 1.98
Influence of publicly available online wait time data on emergency department choice in patients with noncritical complaints. CJEM (2012) 1.98
TRPC channel activation by extracellular thioredoxin. Nature (2008) 1.97
Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem (2005) 1.95
Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX. Proc Natl Acad Sci U S A (2009) 1.94
Allocating scarce resources in real-time to reduce heart failure readmissions: a prospective, controlled study. BMJ Qual Saf (2013) 1.94