Published in J Gerontol A Biol Sci Med Sci on October 21, 2011
Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production? J Gerontol A Biol Sci Med Sci (2012) 1.69
Mitochondria and cardiovascular aging. Circ Res (2012) 1.46
Aging, atherosclerosis, and IGF-1. J Gerontol A Biol Sci Med Sci (2012) 1.16
The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances. J Gerontol A Biol Sci Med Sci (2012) 1.14
Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation. J Gerontol A Biol Sci Med Sci (2012) 1.12
Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment. J Gerontol A Biol Sci Med Sci (2012) 1.12
Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med (2012) 1.12
Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging. J Gerontol A Biol Sci Med Sci (2012) 1.09
SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Res (2016) 1.08
Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease. J Gerontol A Biol Sci Med Sci (2013) 1.07
Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies. J Gerontol A Biol Sci Med Sci (2012) 1.02
Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging. J Gerontol A Biol Sci Med Sci (2011) 0.99
Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice. Am J Physiol Heart Circ Physiol (2013) 0.96
Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci (2012) 0.95
Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase. Am J Physiol Heart Circ Physiol (2013) 0.93
Reductions in serum IGF-1 during aging impair health span. Aging Cell (2013) 0.93
Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells. J Gerontol A Biol Sci Med Sci (2012) 0.92
Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in β-amyloid generation and Alzheimer's disease. Am J Physiol Heart Circ Physiol (2013) 0.92
IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice. J Cereb Blood Flow Metab (2014) 0.91
Nrf2 and cardiovascular defense. Oxid Med Cell Longev (2013) 0.91
Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. J Gerontol A Biol Sci Med Sci (2014) 0.91
Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity. J Gerontol A Biol Sci Med Sci (2013) 0.89
Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients. J Gerontol A Biol Sci Med Sci (2012) 0.88
Impaired vascular endothelial growth factor A and inflammation in patients with peripheral artery disease. Angiology (2013) 0.87
Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol (2014) 0.87
IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging. Aging Cell (2015) 0.86
Treatment with the cytochrome P450 ω-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats. Br J Pharmacol (2013) 0.85
Insulin-like growth factor-1 regulates glutathione peroxidase expression and activity in vascular endothelial cells: Implications for atheroprotective actions of insulin-like growth factor-1. Biochim Biophys Acta (2012) 0.85
Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice. J Gerontol A Biol Sci Med Sci (2013) 0.84
Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype? J Gerontol A Biol Sci Med Sci (2012) 0.83
NADPH oxidases: key modulators in aging and age-related cardiovascular diseases? Clin Sci (Lond) (2016) 0.82
Determination of the total mass of antioxidant substances and antioxidant capacity per unit mass in serum using redox titration. Bioinorg Chem Appl (2014) 0.81
Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats. J Gerontol A Biol Sci Med Sci (2014) 0.80
Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci (2014) 0.78
Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr) (2016) 0.78
HDAC inhibitors increase NRF2-signaling in tumour cells and blunt the efficacy of co-adminstered cytotoxic agents. PLoS One (2014) 0.77
The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research. Cell Metab (2016) 0.77
Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline. Exp Gerontol (2016) 0.77
Diverging antioxidative responses to IGF-1 in cultured human skin fibroblasts versus vascular endothelial cells. J Gerontol A Biol Sci Med Sci (2012) 0.77
Reversal of age-related learning deficiency by the vertebrate PACAP and IGF-1 in a novel invertebrate model of aging: the pond snail (Lymnaea stagnalis). J Gerontol A Biol Sci Med Sci (2014) 0.77
Functional Vascular Contributions to Cognitive Impairment and Dementia (VCID): Mechanisms and Consequences of Cerebral Microvascular Dysfunction in Aging. Am J Physiol Heart Circ Physiol (2016) 0.76
Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat. J Gerontol A Biol Sci Med Sci (2014) 0.76
Vitamin D modulates the association of circulating insulin-like growth factor-1 with carotid artery intima-media thickness. Atherosclerosis (2014) 0.76
Autologous Bone Marrow Mononuclear Cell Transplantation Delays Progression of Carotid Atherosclerosis in Rabbits. Mol Neurobiol (2015) 0.75
Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell (2017) 0.75
Cerebral microhemorrhages: mechanisms, consequences and prevention. Am J Physiol Heart Circ Physiol (2017) 0.75
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab (2008) 6.22
Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group. Lancet (2001) 4.14
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans. Sci Transl Med (2011) 3.84
Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study. Am J Med (2003) 3.54
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res (2002) 3.51
Premature mortality due to cardiovascular disease in hypopituitarism. Lancet (1990) 2.92
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter. Mol Cell Biol (2002) 2.82
Increased cerebrovascular mortality in patients with hypopituitarism. Clin Endocrinol (Oxf) (1997) 2.54
Inflammation and endothelial dysfunction during aging: role of NF-kappaB. J Appl Physiol (1985) (2008) 2.40
Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels. Arterioscler Thromb Vasc Biol (2003) 2.26
Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci (2010) 2.24
Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study. Ann Intern Med (2003) 2.20
Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition. Am J Physiol Heart Circ Physiol (2006) 2.19
Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries. Am J Physiol Heart Circ Physiol (2007) 2.16
Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. J Biol Chem (2003) 2.06
Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. Am J Pathol (2007) 2.02
Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc Natl Acad Sci U S A (2008) 1.97
Skin-derived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone. Aging Cell (2006) 1.89
Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes. Circ Res (2009) 1.88
Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circ Res (2008) 1.75
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol (2010) 1.73
Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. Physiol Genomics (2004) 1.73
The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: the Rancho Bernardo Study. J Clin Endocrinol Metab (2004) 1.70
Impaired growth hormone secretion in the adult population: relation to age and adiposity. J Clin Invest (1981) 1.69
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech Ageing Dev (2009) 1.69
IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice. Arterioscler Thromb Vasc Biol (2007) 1.64
Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity. Aging Cell (2007) 1.62
Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice. Am J Physiol Heart Circ Physiol (2008) 1.55
Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats. Am J Physiol Heart Circ Physiol (2008) 1.52
Insulin-like growth factor-I affects perinatal lethality and postnatal development in a gene dosage-dependent manner: manipulation using the Cre/loxP system in transgenic mice. Mol Endocrinol (1998) 1.52
Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice. Neurobiol Aging (2005) 1.49
Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span. Endocrinology (2005) 1.45
High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling. J Neurochem (2010) 1.43
Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia. Am J Physiol Heart Circ Physiol (2011) 1.42
Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice. J Clin Invest (1997) 1.37
Stress resistance and aging: influence of genes and nutrition. Mech Ageing Dev (2006) 1.36
Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF-1), IGF-1 gene expression, and IGF-1 binding proteins. J Gerontol (1991) 1.33
Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice. FASEB J (2010) 1.33
Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. J Gerontol A Biol Sci Med Sci (2011) 1.31
Growth hormone, insulin-like growth factor-1 and the aging cardiovascular system. Cardiovasc Res (2002) 1.30
The effect of hypopituitarism on life expectancy. J Clin Endocrinol Metab (1996) 1.28
Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice. Horm Metab Res (2002) 1.25
Longevity and age-related pathology of mice deficient in pregnancy-associated plasma protein-A. J Gerontol A Biol Sci Med Sci (2010) 1.25
Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response. Am J Physiol Heart Circ Physiol (2011) 1.22
Insulin-like growth factor 1 as a predictor of ischemic stroke outcome in the elderly. Am J Med (2004) 1.21
Long-lived ames dwarf mice are resistant to chemical stressors. J Gerontol A Biol Sci Med Sci (2009) 1.18
NRF2-dependent glutamate-L-cysteine ligase catalytic subunit expression mediates insulin protection against hyperglycemia- induced brain endothelial cell apoptosis. Curr Neurovasc Res (2006) 1.14
Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus. Am J Physiol Heart Circ Physiol (2009) 1.13
Smooth muscle cell-specific insulin-like growth factor-1 overexpression in Apoe-/- mice does not alter atherosclerotic plaque burden but increases features of plaque stability. Arterioscler Thromb Vasc Biol (2010) 1.11
Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal. J Gerontol A Biol Sci Med Sci (2011) 1.11
The effects of growth hormone (GH) treatment on GH and insulin/IGF-1 signaling in long-lived Ames dwarf mice. J Gerontol A Biol Sci Med Sci (2009) 1.10
Is altered expression of hepatic insulin-related genes in growth hormone receptor knockout mice due to GH resistance or a difference in biological life spans? J Gerontol A Biol Sci Med Sci (2009) 1.09
Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats. J Gerontol A Biol Sci Med Sci (2010) 1.07
Insulin-like growth factor-1 receptor activation inhibits oxidized LDL-induced cytochrome C release and apoptosis via the phosphatidylinositol 3 kinase/Akt signaling pathway. Arterioscler Thromb Vasc Biol (2003) 1.06
Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment. J Gerontol A Biol Sci Med Sci (2011) 1.03
Endothelial dysfunction in hypopituitary adults with growth hormone deficiency. Clin Endocrinol (Oxf) (1999) 1.00
IGF-1, oxidative stress and atheroprotection. Trends Endocrinol Metab (2010) 0.99
Effects of growth hormone and thyroxine replacement therapy on insulin signaling in Ames dwarf mice. J Gerontol A Biol Sci Med Sci (2010) 0.97
High insulinlike growth factor binding protein 1 level predicts incident congestive heart failure in the elderly. Am Heart J (2008) 0.97
Long-living Ames dwarf mouse hepatocytes readily undergo apoptosis. Exp Gerontol (2003) 0.97
Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS). Aging (Albany NY) (2009) 0.93
PI3K and ERK/Nrf2 pathways are involved in oleanolic acid-induced heme oxygenase-1 expression in rat vascular smooth muscle cells. J Cell Biochem (2011) 0.92
Optimized adeno-associated virus 8 produces hepatocyte-specific Cre-mediated recombination without toxicity or affecting liver regeneration. Am J Physiol Gastrointest Liver Physiol (2008) 0.91
Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice. Am J Physiol Heart Circ Physiol (2011) 0.90
Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression. Neuroscience (2011) 0.90
Effect of a combined treatment with growth hormone and melatonin in the cardiological aging on male SAMP8 mice. J Gerontol A Biol Sci Med Sci (2011) 0.88
The regulation and mechanisms of action of growth hormone and insulin-like growth factor 1 during normal ageing. J Reprod Fertil Suppl (1993) 0.83
Coronary flow reserve is impaired in patients with adult growth hormone (GH) deficiency. Clin Endocrinol (Oxf) (2007) 0.82
The hippocampus of Ames dwarf mice exhibits enhanced antioxidative defenses following kainic acid-induced oxidative stress. Exp Gerontol (2010) 0.81
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab (2008) 6.22
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res (2002) 3.51
Resveratrol induces mitochondrial biogenesis in endothelial cells. Am J Physiol Heart Circ Physiol (2009) 2.65
Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase. Arterioscler Thromb Vasc Biol (2003) 2.52
Inflammation and endothelial dysfunction during aging: role of NF-kappaB. J Appl Physiol (1985) (2008) 2.40
Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci (2010) 2.24
Are sirtuins viable targets for improving healthspan and lifespan? Nat Rev Drug Discov (2012) 2.22
Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation. Am J Physiol Heart Circ Physiol (2007) 2.20
Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition. Am J Physiol Heart Circ Physiol (2006) 2.19
Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries. Am J Physiol Heart Circ Physiol (2007) 2.16
Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries. FASEB J (2003) 2.13
Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. Am J Pathol (2007) 2.02
Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc Natl Acad Sci U S A (2008) 1.97
Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure. Circulation (2005) 1.91
Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol (2008) 1.87
Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol (2006) 1.86
ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo. J Exp Med (2008) 1.86
Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells. Am J Physiol Heart Circ Physiol (2009) 1.85
SRT1720 improves survival and healthspan of obese mice. Sci Rep (2011) 1.81
Resveratrol increases vascular oxidative stress resistance. Am J Physiol Heart Circ Physiol (2007) 1.81
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. Am J Physiol Heart Circ Physiol (2007) 1.77
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem Int (2008) 1.76
Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circ Res (2008) 1.75
What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One (2011) 1.74
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol (2010) 1.73
Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. Physiol Genomics (2004) 1.73
High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase. Circulation (2003) 1.73
Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants. Ann Neurol (2012) 1.71
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech Ageing Dev (2009) 1.69
Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production? J Gerontol A Biol Sci Med Sci (2012) 1.69
Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress. Arterioscler Thromb Vasc Biol (2009) 1.63
Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats. Hypertension (2009) 1.63
Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity. Aging Cell (2007) 1.62
A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36. J Biol Chem (2006) 1.61
Hyperhomocysteinemia, a cardiac metabolic disease: role of nitric oxide and the p22phox subunit of NADPH oxidase. Circulation (2005) 1.55
Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice. Am J Physiol Heart Circ Physiol (2008) 1.55
Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats. Am J Physiol Heart Circ Physiol (2008) 1.52
PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress. Arterioscler Thromb Vasc Biol (2005) 1.47
Mitochondria and cardiovascular aging. Circ Res (2012) 1.46
Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology. Cardiovasc Res (2010) 1.45
PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes. Am J Physiol Heart Circ Physiol (2003) 1.43
Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia. Am J Physiol Heart Circ Physiol (2011) 1.42
Patient-ventilator asynchrony in a traumatically injured population. Respir Care (2013) 1.42
Type 2 diabetic mice have increased arteriolar tone and blood pressure: enhanced release of COX-2-derived constrictor prostaglandins. Arterioscler Thromb Vasc Biol (2005) 1.42
A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan. Trends Genet (2002) 1.40
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. Am J Pathol (2008) 1.35
Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen. Curr Med Chem (2006) 1.35
Superoxide-NO interaction decreases flow- and agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol (2003) 1.32
Spatial learning and memory deficits after whole-brain irradiation are associated with changes in NMDA receptor subunits in the hippocampus. Radiat Res (2006) 1.31
Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. J Gerontol A Biol Sci Med Sci (2011) 1.31
Characterization of acute brain injuries and neurobehavioral profiles in a rabbit model of germinal matrix hemorrhage. Stroke (2008) 1.30
Oxidative stress and accelerated vascular aging: implications for cigarette smoking. Front Biosci (Landmark Ed) (2009) 1.30
Growth hormone, insulin-like growth factor-1 and the aging cardiovascular system. Cardiovasc Res (2002) 1.30
Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. Curr Vasc Pharmacol (2005) 1.29
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. Am J Pathol (2004) 1.28
Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability. Exp Neurol (2008) 1.27
Angiogenic inhibition reduces germinal matrix hemorrhage. Nat Med (2007) 1.27
Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries. Am J Physiol Heart Circ Physiol (2003) 1.27
Microvascular plasticity in aging. Ageing Res Rev (2003) 1.24
Oxidative stress in vascular senescence: lessons from successfully aging species. Front Biosci (2008) 1.24
Consequences of intraventricular hemorrhage in a rabbit pup model. Stroke (2009) 1.24
Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response. Am J Physiol Heart Circ Physiol (2011) 1.22