Published in Cell on October 28, 2011
Molecular machines governing exocytosis of synaptic vesicles. Nature (2012) 3.66
Phosphoinositides: tiny lipids with giant impact on cell regulation. Physiol Rev (2013) 3.21
UNC-13L, UNC-13S, and Tomosyn form a protein code for fast and slow neurotransmitter release in Caenorhabditis elegans. Elife (2013) 1.57
Molecular mechanisms for synchronous, asynchronous, and spontaneous neurotransmitter release. Annu Rev Physiol (2013) 1.41
Synaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter release. Neuron (2013) 1.32
Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion. J Cell Biol (2011) 1.19
Synaptic vesicle recycling: steps and principles. EMBO J (2014) 1.08
Reelin mobilizes a VAMP7-dependent synaptic vesicle pool and selectively augments spontaneous neurotransmission. Neuron (2013) 1.07
Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels. Nat Commun (2013) 1.01
The SNARE Machinery in Mast Cell Secretion. Front Immunol (2012) 0.98
GPCR mediated regulation of synaptic transmission. Prog Neurobiol (2012) 0.98
Calcium channels and short-term synaptic plasticity. J Biol Chem (2013) 0.97
Mutant SNAP25B causes myasthenia, cortical hyperexcitability, ataxia, and intellectual disability. Neurology (2014) 0.97
Calcium regulation of spontaneous and asynchronous neurotransmitter release. Cell Calcium (2012) 0.95
Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment. Elife (2014) 0.95
Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission. Nat Neurosci (2014) 0.93
Ca2+-Calmodulin regulates SNARE assembly and spontaneous neurotransmitter release via v-ATPase subunit V0a1. J Cell Biol (2014) 0.91
Doc2b promotes GLUT4 exocytosis by activating the SNARE-mediated fusion reaction in a calcium- and membrane bending-dependent manner. Mol Biol Cell (2013) 0.91
Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter release. Genes Dev (2012) 0.90
Molecular mechanisms governing Ca(2+) regulation of evoked and spontaneous release. Nat Neurosci (2015) 0.89
Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity. Hum Mol Genet (2013) 0.87
Zebrafish homologs of genes within 16p11.2, a genomic region associated with brain disorders, are active during brain development, and include two deletion dosage sensor genes. Dis Model Mech (2012) 0.86
Mitochondria and plasma membrane Ca2+-ATPase control presynaptic Ca2+ clearance in capsaicin-sensitive rat sensory neurons. J Physiol (2013) 0.85
Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca2+ channels via microdomain coupling. J Neurosci (2012) 0.85
Molecular underpinnings of synaptic vesicle pool heterogeneity. Traffic (2015) 0.85
Asynchronous Ca2+ current conducted by voltage-gated Ca2+ (CaV)-2.1 and CaV2.2 channels and its implications for asynchronous neurotransmitter release. Proc Natl Acad Sci U S A (2012) 0.84
LKB1 Regulates Mitochondria-Dependent Presynaptic Calcium Clearance and Neurotransmitter Release Properties at Excitatory Synapses along Cortical Axons. PLoS Biol (2016) 0.84
Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held. J Neurosci (2012) 0.82
A sequential vesicle pool model with a single release sensor and a Ca(2+)-dependent priming catalyst effectively explains Ca(2+)-dependent properties of neurosecretion. PLoS Comput Biol (2013) 0.82
Vesicles derived via AP-3-dependent recycling contribute to asynchronous release and influence information transfer. Nat Commun (2014) 0.81
Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc Natl Acad Sci U S A (2013) 0.81
Different states of synaptotagmin regulate evoked versus spontaneous release. Nat Commun (2016) 0.79
Structural elements that underlie Doc2β function during asynchronous synaptic transmission. Proc Natl Acad Sci U S A (2015) 0.79
Mutations that disrupt Ca²⁺-binding activity endow Doc2β with novel functional properties during synaptic transmission. Mol Biol Cell (2013) 0.78
An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission. J Neurosci (2015) 0.78
DOC2B and Munc13-1 differentially regulate neuronal network activity. Cereb Cortex (2013) 0.78
Different types of retinal inhibition have distinct neurotransmitter release properties. J Neurophysiol (2015) 0.78
Transcriptomics of maternal and fetal membranes can discriminate between gestational-age matched preterm neonates with and without cognitive impairment diagnosed at 18-24 months. PLoS One (2015) 0.78
Asynchronous presynaptic glutamate release enhances neuronal excitability during the post-spike refractory period. J Physiol (2016) 0.77
Functionally heterogeneous synaptic vesicle pools support diverse synaptic signalling. J Physiol (2015) 0.77
A Developmental Switch for Hebbian Plasticity. PLoS Comput Biol (2015) 0.77
Dueling Ca2+ sensors in neurotransmitter release. Cell (2011) 0.77
Molecular Machines Regulating the Release Probability of Synaptic Vesicles at the Active Zone. Front Synaptic Neurosci (2016) 0.77
Transmembrane tethering of synaptotagmin to synaptic vesicles controls multiple modes of neurotransmitter release. Proc Natl Acad Sci U S A (2015) 0.76
Catecholamine exocytosis during low frequency stimulation in mouse adrenal chromaffin cells is primarily asynchronous and controlled by the novel mechanism of Ca2+ syntilla suppression. J Physiol (2014) 0.76
Slow changes in Ca2(+) cause prolonged release from GABAergic retinal amacrine cells. J Neurophysiol (2013) 0.76
Distinct Calcium Sources Support Multiple Modes of Synaptic Release from Cranial Sensory Afferents. J Neurosci (2016) 0.76
Shaping Neuronal Network Activity by Presynaptic Mechanisms. PLoS Comput Biol (2015) 0.76
Increased asynchronous GABA release causes more inhibition in human epileptic brain? Acta Pharmacol Sin (2012) 0.76
Fast-scan cyclic voltammetry demonstrates that L-DOPA produces dose-dependent regionally selective, bimodal effects on striatal dopamine kinetics in vivo. J Neurochem (2015) 0.75
Porosome in Cystic Fibrosis. Discoveries (Craiova) (2015) 0.75
Dynasore blocks evoked release while augmenting spontaneous synaptic transmission from primary visceral afferents. PLoS One (2017) 0.75
Short-term potentiation of GABAergic synaptic inputs to vasopressin and oxytocin neurones. J Physiol (2014) 0.75
Munc13-4 functions as a Ca2+ sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles. Mol Biol Cell (2017) 0.75
Ring-like oligomers of Synaptotagmins and related C2 domain proteins. Elife (2016) 0.75
Loss of Doc2-dependent spontaneous neurotransmission augments glutamatergic synaptic strength. J Neurosci (2017) 0.75
Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse. Cell (1994) 7.43
How does synaptotagmin trigger neurotransmitter release? Annu Rev Biochem (2008) 4.20
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse. Nature (2007) 3.91
Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell (2006) 3.71
Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs. Science (2004) 3.24
Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release. Neuron (2005) 3.09
Ca(2+)-synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion. Nat Struct Mol Biol (2006) 2.74
AMPA receptor incorporation into synapses during LTP: the role of lateral movement and exocytosis. Neuron (2009) 2.64
Inhibitory transmission mediated by asynchronous transmitter release. Neuron (2000) 2.62
The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo. Nature (2002) 2.60
Multivesicular release from excitatory synapses of cultured hippocampal neurons. Neuron (1994) 2.21
Synaptotagmin I, a Ca2+ sensor for neurotransmitter release. Trends Neurosci (2003) 2.17
Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release. Science (2010) 2.12
Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+. Nat Struct Mol Biol (2008) 2.11
Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis. Proc Natl Acad Sci U S A (2005) 1.88
Dual roles of the C2B domain of synaptotagmin I in synchronizing Ca2+-dependent neurotransmitter release. J Neurosci (2004) 1.85
Synaptotagmins I and IV promote transmitter release independently of Ca(2+) binding in the C(2)A domain. Nature (2002) 1.83
Competition between phasic and asynchronous release for recovered synaptic vesicles at developing hippocampal autaptic synapses. J Neurosci (2004) 1.76
Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release. Nat Neurosci (2009) 1.74
Synaptotagmin I synchronizes transmitter release in mouse hippocampal neurons. J Neurosci (2004) 1.73
Extrasynaptic glutamate spillover in the hippocampus: evidence and implications. Trends Neurosci (1998) 1.72
Primary afferent activation of thermosensitive TRPV1 triggers asynchronous glutamate release at central neurons. Neuron (2010) 1.68
Synaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusion. Mol Biol Cell (2005) 1.67
Properties of synchronous and asynchronous release during pulse train depression in cultured hippocampal neurons. J Neurophysiol (2001) 1.59
DOC2 proteins in rat brain: complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion. Neuron (1997) 1.56
Synaptotagmin has an essential function in synaptic vesicle positioning for synchronous release in addition to its role as a calcium sensor. Neuron (2009) 1.48
Physical and functional interactions of Doc2 and Munc13 in Ca2+-dependent exocytotic machinery. J Biol Chem (1997) 1.46
Inhibitory regulation of electrically coupled neurons in the inferior olive is mediated by asynchronous release of GABA. Neuron (2009) 1.44
Synaptic mechanisms of persistent reverberatory activity in neuronal networks. Proc Natl Acad Sci U S A (2005) 1.43
Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism. Neuron (2011) 1.33
Autapses and networks of hippocampal neurons exhibit distinct synaptic transmission phenotypes in the absence of synaptotagmin I. J Neurosci (2009) 1.29
Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis. Proc Natl Acad Sci U S A (2008) 1.29
Molecular frequency filters at central synapses. Prog Neurobiol (2000) 1.28
Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction. Proc Natl Acad Sci U S A (2010) 1.28
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion. J Cell Biol (2010) 1.28
Synaptotagmin C2B domain regulates Ca2+-triggered fusion in vitro: critical residues revealed by scanning alanine mutagenesis. J Biol Chem (2008) 1.25
Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor. Mol Cell Biol (2005) 1.24
Doc2: a novel brain protein having two repeated C2-like domains. Biochem Biophys Res Commun (1995) 1.20
Integration of asynchronously released quanta prolongs the postsynaptic spike window. J Neurosci (2007) 1.20
Mechanism and function of synaptotagmin-mediated membrane apposition. Nat Struct Mol Biol (2011) 1.19
SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming. Neuron (2010) 1.16
DOC2A and DOC2B are sensors for neuronal activity with unique calcium-dependent and kinetic properties. J Neurochem (2006) 1.12
Doc2alpha is an activity-dependent modulator of excitatory synaptic transmission. Eur J Neurosci (1999) 1.05
Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells. J Immunol (2008) 1.03
DOC2B acts as a calcium switch and enhances vesicle fusion. J Neurosci (2008) 1.02
Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo. J Biol Chem (1999) 1.02
Doc2 enhances Ca2+-dependent exocytosis from PC12 cells. J Biol Chem (1996) 1.01
Role of the Doc2 alpha-Munc13-1 interaction in the neurotransmitter release process. Proc Natl Acad Sci U S A (1998) 1.01
The transmembrane domain of syntaxin 1A is critical for cytoplasmic domain protein-protein interactions. J Biol Chem (2001) 0.99
Molecular cloning of an isoform of Doc2 having two C2-like domains. Biochem Biophys Res Commun (1995) 0.99
Calcium-dependent phospholipid binding to the C2A domain of a ubiquitous form of double C2 protein (Doc2 beta). J Biochem (1996) 0.96
Ca(2+)-induced recruitment of the secretory vesicle protein DOC2B to the target membrane. J Biol Chem (2004) 0.93
The muscle protein dysferlin accumulates in the Alzheimer brain. Acta Neuropathol (2006) 0.91
Brevity of the Ca2+ microdomain and active zone geometry prevent Ca2+-sensor saturation for neurotransmitter release. J Neurophysiol (2005) 0.91
Role of the polybasic sequence in the Doc2alpha C2B domain in dense-core vesicle exocytosis in PC12 cells. J Neurochem (2010) 0.89
Calcium and synaptic dynamics underlying reverberatory activity in neuronal networks. Phys Biol (2007) 0.87
Interactions between asynchronous release and short-term plasticity in the nucleus accumbens slice. J Neurophysiol (2005) 0.85
Molecular cloning of mouse Doc2alpha and distribution of its mRNA in adult mouse brain. Brain Res Mol Brain Res (1997) 0.85
Doc2gamma, a third isoform of double C2 protein, lacking calcium-dependent phospholipid binding activity. Biochem Biophys Res Commun (2000) 0.84
Different spatiotemporal expression of DOC2 genes in the developing rat brain argues for an additional, nonsynaptic role of DOC2B in early development. Eur J Neurosci (2000) 0.81
SV2 is the protein receptor for botulinum neurotoxin A. Science (2006) 4.51
Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis. Science (2004) 3.81
Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs. Science (2004) 3.24
PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane. Nat Struct Mol Biol (2003) 2.95
Ca(2+)-synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion. Nat Struct Mol Biol (2006) 2.74
Synaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusion. Cell (2009) 2.47
Fusion pores and fusion machines in Ca2+-triggered exocytosis. Annu Rev Biophys Biomol Struct (2006) 2.21
Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+. Nat Struct Mol Biol (2008) 2.11
Different domains of synaptotagmin control the choice between kiss-and-run and full fusion. Nature (2003) 2.08
SNARE-driven, 25-millisecond vesicle fusion in vitro. Biophys J (2005) 2.08
Structural basis of cell surface receptor recognition by botulinum neurotoxin B. Nature (2006) 1.97
Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions. Neuron (2004) 1.96
Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis. Proc Natl Acad Sci U S A (2005) 1.88
Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells. J Cell Biol (2003) 1.81
The C2 domains of synaptotagmin--partners in exocytosis. Trends Biochem Sci (2004) 1.74
Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release. Nat Neurosci (2009) 1.74
Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells. J Neurosci (2010) 1.72
Two modes of exocytosis at hippocampal synapses revealed by rate of FM1-43 efflux from individual vesicles. J Cell Biol (2005) 1.72
Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron (2011) 1.71
Synaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusion. Mol Biol Cell (2005) 1.67
Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons. Mol Biol Cell (2008) 1.66
CAPS acts at a prefusion step in dense-core vesicle exocytosis as a PIP2 binding protein. Neuron (2004) 1.58
The fusion pores of Ca2+ -triggered exocytosis. Nat Struct Mol Biol (2008) 1.57
C2A activates a cryptic Ca(2+)-triggered membrane penetration activity within the C2B domain of synaptotagmin I. Proc Natl Acad Sci U S A (2002) 1.56
Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin I. Biophys J (2006) 1.52
Synaptotagmin-Ca2+ triggers two sequential steps in regulated exocytosis in rat PC12 cells: fusion pore opening and fusion pore dilation. J Physiol (2005) 1.51
Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells. J Cell Biol (2003) 1.51
Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells. Proc Natl Acad Sci U S A (2004) 1.40
Ca2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes. J Cell Biol (2006) 1.37
Single molecule mechanical probing of the SNARE protein interactions. Biophys J (2006) 1.35
Postsynaptic Neuroligin1 regulates presynaptic maturation. Proc Natl Acad Sci U S A (2009) 1.31
Visualization of synaptotagmin I oligomers assembled onto lipid monolayers. Proc Natl Acad Sci U S A (2003) 1.30
Autapses and networks of hippocampal neurons exhibit distinct synaptic transmission phenotypes in the absence of synaptotagmin I. J Neurosci (2009) 1.29
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion. J Cell Biol (2010) 1.28
Role of synaptotagmin in Ca2+-triggered exocytosis. Biochem J (2002) 1.27
Mutations in the effector binding loops in the C2A and C2B domains of synaptotagmin I disrupt exocytosis in a nonadditive manner. J Biol Chem (2003) 1.26
Uncoupling the roles of synaptotagmin I during endo- and exocytosis of synaptic vesicles. Nat Neurosci (2011) 1.26
Synaptotagmin C2B domain regulates Ca2+-triggered fusion in vitro: critical residues revealed by scanning alanine mutagenesis. J Biol Chem (2008) 1.25
Lipid mixing and content release in single-vesicle, SNARE-driven fusion assay with 1-5 ms resolution. Biophys J (2009) 1.25
Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor. Mol Cell Biol (2005) 1.24
Mechanism and function of synaptotagmin-mediated membrane apposition. Nat Struct Mol Biol (2011) 1.19
Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion. J Cell Biol (2011) 1.19
Analysis of the synaptotagmin family during reconstituted membrane fusion. Uncovering a class of inhibitory isoforms. J Biol Chem (2008) 1.18
SV2 mediates entry of tetanus neurotoxin into central neurons. PLoS Pathog (2010) 1.15
Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons. J Cell Biol (2007) 1.15
Synaptotagmin IV: a multifunctional regulator of peptidergic nerve terminals. Nat Neurosci (2009) 1.10
Concurrent binding of complexin and synaptotagmin to liposome-embedded SNARE complexes. Biochemistry (2009) 1.09
Molecular regulation of membrane resealing in 3T3 fibroblasts. J Biol Chem (2004) 1.08
Productive hemifusion intermediates in fast vesicle fusion driven by neuronal SNAREs. Biophys J (2007) 1.07
Receptor binding enables botulinum neurotoxin B to sense low pH for translocation channel assembly. Cell Host Microbe (2011) 1.06
Phosphatidylserine regulation of Ca2+-triggered exocytosis and fusion pores in PC12 cells. Mol Biol Cell (2009) 1.05
Botulinum toxin type B micromechanosensor. Proc Natl Acad Sci U S A (2003) 1.05
Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo. J Neurosci (2011) 1.04
Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane implicates proximity of cocaine and substrate active sites. Mol Pharmacol (2008) 1.03
ESCRT-0 assembles as a heterotetrameric complex on membranes and binds multiple ubiquitinylated cargoes simultaneously. J Biol Chem (2010) 1.01
Ca2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivo. J Neurosci (2008) 1.01
Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission. J Neurosci (2012) 0.99
Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells. Mol Biol Cell (2011) 0.98
MARCKS-ED peptide as a curvature and lipid sensor. ACS Chem Biol (2012) 0.97
Regulation of exocytosis and fusion pores by synaptotagmin-effector interactions. Mol Biol Cell (2010) 0.96
Distinct subsets of Syt-IV/BDNF vesicles are sorted to axons versus dendrites and recruited to synapses by activity. J Neurosci (2012) 0.95
Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment. Elife (2014) 0.95
Axonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screen. Mol Biol Cell (2012) 0.94
Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding. J Mol Biol (2010) 0.93
Synaptotagmin perturbs the structure of phospholipid bilayers. Biochemistry (2008) 0.92
Affinity labeling the dopamine transporter ligand binding site. J Neurosci Methods (2004) 0.90
Expression of mutant huntingtin blocks exocytosis in PC12 cells by depletion of complexin II. J Biol Chem (2003) 0.89
Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure. Proc Natl Acad Sci U S A (2013) 0.89
SNAP-23 functions in docking/fusion of granules at low Ca2+. Mol Biol Cell (2004) 0.88
Glycosylation is dispensable for sorting of synaptotagmin 1 but is critical for targeting of SV2 and synaptophysin to recycling synaptic vesicles. J Biol Chem (2012) 0.88
Biophysical characterization of styryl dye-membrane interactions. Biophys J (2009) 0.87
Atomic force microscope spectroscopy reveals a hemifusion intermediate during soluble N-ethylmaleimide-sensitive factor-attachment protein receptors-mediated membrane fusion. Biophys J (2007) 0.86
Botulinum neurotoxins B and E translocate at different rates and exhibit divergent responses to GT1b and low pH. Biochemistry (2012) 0.85
Detection of highly curved membrane surfaces using a cyclic peptide derived from synaptotagmin-I. ACS Chem Biol (2012) 0.85
Pulling force generated by interacting SNAREs facilitates membrane hemifusion. Integr Biol (Camb) (2009) 0.84
Syntaxin requirement for Ca2+-triggered exocytosis in neurons and endocrine cells demonstrated with an engineered neurotoxin. Biochemistry (2011) 0.83
Detection of botulinum toxins: micromechanical and fluorescence-based sensors. Croat Med J (2005) 0.83
Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor. Br J Pharmacol (2005) 0.83
Permeation of styryl dyes through nanometer-scale pores in membranes. Biochemistry (2011) 0.82
Application of fluorescent probes to study mechanics and dynamics of Ca2+-triggered synaptotagmin C2 domain-membrane interactions. Methods Enzymol (2003) 0.81
Rat and Drosophila synaptotagmin 4 have opposite effects during SNARE-catalyzed membrane fusion. J Biol Chem (2010) 0.81
Multivalency amplifies the selection and affinity of bradykinin-derived peptides for lipid nanovesicles. Mol Biosyst (2013) 0.80
ENaC subunit-subunit interactions and inhibition by syntaxin 1A. Am J Physiol Renal Physiol (2004) 0.79
Mutations that disrupt Ca²⁺-binding activity endow Doc2β with novel functional properties during synaptic transmission. Mol Biol Cell (2013) 0.78
All three components of the neuronal SNARE complex contribute to secretory vesicle docking. J Cell Biol (2012) 0.77
Activation of postsynaptic Ca(2+) stores modulates glutamate receptor cycling in hippocampal neurons. J Neurophysiol (2005) 0.77
Retargeted clostridial neurotoxins as novel agents for treating chronic diseases. Biochemistry (2011) 0.77
"Self" versus "non-self" connectivity dictates properties of synaptic transmission and plasticity. PLoS One (2013) 0.75