Published in Cell Res on November 08, 2011
Cephalopods in neuroscience: regulations, research and the 3Rs. Invert Neurosci (2014) 1.02
Modulation of firing and synaptic transmission of serotonergic neurons by intrinsic G protein-coupled receptors and ion channels. Front Integr Neurosci (2013) 0.82
Sonic hedgehog and Wnt: antagonists in morphogenesis but collaborators in axon guidance. Front Cell Neurosci (2013) 0.82
Pancreatic stellate cells contribute pancreatic cancer pain via activation of sHH signaling pathway. Oncotarget (2016) 0.77
Shh goes multidirectional in axon guidance. Cell Res (2011) 0.76
Peripheral and spinal 5-HT receptors participate in cholestatic itch and antinociception induced by bile duct ligation in rats. Sci Rep (2016) 0.75
Smoothened antagonist GDC-0449 (Vismodegib) inhibits proliferation and triggers apoptosis in colon cancer cell lines. Exp Ther Med (2017) 0.75
The molecular biology of axon guidance. Science (1996) 11.90
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat Genet (1999) 11.79
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature (1996) 11.46
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature (2003) 10.33
Molecular mechanisms of axon guidance. Science (2002) 6.49
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature (1996) 5.69
Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev (1996) 4.94
Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development (2001) 4.89
Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science (2003) 4.18
The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell (2003) 3.66
Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity. Cell (1996) 3.60
Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates. Development (2006) 3.39
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell (1998) 3.33
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network. Development (2008) 3.30
Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping. Nature (2006) 2.92
Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell (2001) 2.84
Regulation of commissural axon pathfinding by slit and its Robo receptors. Annu Rev Cell Dev Biol (2006) 2.76
Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract. Nat Neurosci (2005) 2.76
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest (2004) 2.72
The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal. Cell (1996) 2.58
smoothened encodes a receptor-like serpentine protein required for hedgehog signalling. Nature (1996) 2.37
Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature (2006) 2.29
Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis. Nat Neurosci (2009) 2.03
Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway. Neuron (2009) 1.99
A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube. Mol Cell (2001) 1.99
Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity. J Neurosci (2006) 1.92
Sonic hedgehog signaling by the patched-smoothened receptor complex. Curr Biol (1999) 1.79
Sonic hedgehog guides commissural axons along the longitudinal axis of the spinal cord. Nat Neurosci (2005) 1.75
Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm. Development (1990) 1.71
Lmx1b is essential for the development of serotonergic neurons. Nat Neurosci (2003) 1.70
Wnt canonical pathway restricts graded Shh/Gli patterning activity through the regulation of Gli3 expression. Development (2007) 1.60
Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. J Neurosci (2010) 1.57
Lmx1b, Pet-1, and Nkx2.2 coordinately specify serotonergic neurotransmitter phenotype. J Neurosci (2003) 1.54
Control of retinal ganglion cell axon growth: a new role for Sonic hedgehog. Development (2001) 1.47
Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing. Nat Neurosci (2009) 1.37
Repulsive Wnt signaling inhibits axon regeneration after CNS injury. J Neurosci (2008) 1.36
Gata2 specifies serotonergic neurons downstream of sonic hedgehog. Development (2004) 1.34
Emerging mechanisms in morphogen-mediated axon guidance. Bioessays (2009) 1.32
Cholesterol modification restricts the spread of Shh gradient in the limb bud. Proc Natl Acad Sci U S A (2006) 1.30
Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc. J Neurosci (2010) 1.17
Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site. J Biol Chem (2010) 1.13
Sonic hedgehog has a dual effect on the growth of retinal ganglion axons depending on its concentration. J Neurosci (2005) 1.10
Making a grade: Sonic Hedgehog signalling and the control of neural cell fate. EMBO J (2009) 1.09
EFHC1 interacts with microtubules to regulate cell division and cortical development. Nat Neurosci (2009) 1.09
Postnatal ontogeny of the transcription factor Lmx1b in the mouse central nervous system. J Comp Neurol (2008) 1.09
Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons. Development (2008) 1.08
Regeneration of descending axon tracts after spinal cord injury. Prog Neurobiol (2005) 1.05
Distinct sites of origin of oligodendrocytes and somatic motoneurons in the chick spinal cord: oligodendrocytes arise from Nkx2.2-expressing progenitors by a Shh-dependent mechanism. Development (2001) 1.04
Sonic hedgehog guides post-crossing commissural axons both directly and indirectly by regulating Wnt activity. J Neurosci (2010) 1.03
Negative guidance factor-induced macropinocytosis in the growth cone plays a critical role in repulsive axon turning. J Neurosci (2009) 1.02
Termination patterns of serotoninergic medullary raphespinal fibers in the rat lumbar spinal cord: an anterograde immunohistochemical study. J Comp Neurol (1990) 0.95
Navigating the anterior-posterior axis with Wnts. Neuron (2006) 0.92
Longitudinal axon guidance. Curr Opin Neurobiol (2006) 0.92
Region-specific requirement for cholesterol modification of sonic hedgehog in patterning the telencephalon and spinal cord. Development (2007) 0.91
The morphogen sonic hedgehog collaborates with netrin-1 to guide axons in the spinal cord. Trends Neurosci (2003) 0.88
Serotoninergic medullary raphespinal projection to the lumbar spinal cord in the rat: a retrograde immunohistochemical study. J Comp Neurol (1992) 0.87
Upregulation of Ryk expression in rat dorsal root ganglia after peripheral nerve injury. Brain Res Bull (2008) 0.86
Xenopus sonic hedgehog guides retinal axons along the optic tract. Dev Dyn (2010) 0.83
Use of GFP to analyze morphology, connectivity, and function of cells in the central nervous system. Methods Mol Biol (2009) 0.81
Involvement of 5-hydroxytryptamine(1A) receptors in the descending anti-nociceptive pathway from periaqueductal gray to the spinal dorsal horn in intact rats, rats with nerve injury and rats with inflammation. Neuroscience (2002) 0.81
Axon guidance by molecular gradients. Curr Opin Neurobiol (1992) 0.80
Effect of iodine intake on thyroid diseases in China. N Engl J Med (2006) 5.46
A GAL4-driver line resource for Drosophila neurobiology. Cell Rep (2012) 4.67
Evidence that microRNAs are associated with translating messenger RNAs in human cells. Nat Struct Mol Biol (2006) 3.36
MicroRNA-mediated control of oligodendrocyte differentiation. Neuron (2010) 3.24
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc Natl Acad Sci U S A (2003) 3.21
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. Neuron (2009) 2.72
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proc Natl Acad Sci U S A (2006) 2.63
CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Res (2012) 2.50
Genome-scale functional profiling of the mammalian AP-1 signaling pathway. Proc Natl Acad Sci U S A (2003) 2.45
Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain. Proc Natl Acad Sci U S A (2008) 1.90
An essential role for stromal interaction molecule 1 in neointima formation following arterial injury. Cardiovasc Res (2008) 1.87
Derivation of human embryonic stem cell lines from parthenogenetic blastocysts. Cell Res (2007) 1.83
miR-146a controls the resolution of T cell responses in mice. J Exp Med (2012) 1.81
Mitogen-activated protein kinases mediate upregulation of hypothalamic angiotensin II type 1 receptors in heart failure rats. Hypertension (2008) 1.78
RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects. Breast Cancer Res Treat (2010) 1.74
Polymorphisms of tumor necrosis factor-alpha and breast cancer risk: a meta-analysis. Breast Cancer Res Treat (2010) 1.70
Influenza H7N9 and H9N2 viruses: coexistence in poultry linked to human H7N9 infection and genome characteristics. J Virol (2014) 1.67
Mach-Zehnder interferometry in a strongly driven superconducting qubit. Science (2005) 1.65
Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophrenia. Neuron (2011) 1.57
Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation. J Biol Chem (2009) 1.56
mGRASP enables mapping mammalian synaptic connectivity with light microscopy. Nat Methods (2011) 1.53
DJ-1 may contribute to metastasis of non-small cell lung cancer. Mol Biol Rep (2011) 1.52
A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila. Mol Cell (2013) 1.49
Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophrenia. Cell (2012) 1.48
Aldosterone acts centrally to increase brain renin-angiotensin system activity and oxidative stress in normal rats. Am J Physiol Heart Circ Physiol (2007) 1.46
Lack of an association between AURKA T91A polymorphisms and breast cancer: a meta-analysis involving 32,141 subjects. Breast Cancer Res Treat (2010) 1.46
Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunity. J Interferon Cytokine Res (2010) 1.45
Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure. Circ Res (2006) 1.40
De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer. J Transl Med (2012) 1.40
Free volume in imidazolium triflimide ([C3MIM][NTf2]) ionic liquid from positron lifetime: amorphous, crystalline, and liquid states. J Chem Phys (2010) 1.34
Analysis of differential BRAF(V600E) mutational status in high aggressive papillary thyroid microcarcinoma. Ann Surg Oncol (2008) 1.34
Metabolomics coupled with proteomics advancing drug discovery toward more agile development of targeted combination therapies. Mol Cell Proteomics (2013) 1.34
Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway. Am J Physiol Heart Circ Physiol (2009) 1.32
Hierarchical leak detection and localization method in natural gas pipeline monitoring sensor networks. Sensors (Basel) (2011) 1.32
Radiological presentations in relation to curve severity in scoliosis associated with syringomyelia. J Pediatr Orthop (2007) 1.28
HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions. J Cell Biol (2008) 1.27
Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1. Mol Endocrinol (2011) 1.23
PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation. Cell Signal (2008) 1.23
Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. Am J Physiol Heart Circ Physiol (2010) 1.21
Overexpression of microRNA OsmiR397 improves rice yield by increasing grain size and promoting panicle branching. Nat Biotechnol (2013) 1.20
Advanced glycation endproducts alter functions and promote apoptosis in endothelial progenitor cells through receptor for advanced glycation endproducts mediate overpression of cell oxidant stress. Mol Cell Biochem (2009) 1.19
USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase. J Exp Med (2014) 1.18
Genome-wide screening and functional analysis identify a large number of long noncoding RNAs involved in the sexual reproduction of rice. Genome Biol (2014) 1.18
Transgenic rhesus monkeys produced by gene transfer into early-cleavage-stage embryos using a simian immunodeficiency virus-based vector. Proc Natl Acad Sci U S A (2010) 1.18
Discrepancy between radiographic shoulder balance and cosmetic shoulder balance in adolescent idiopathic scoliosis patients with double thoracic curve. Eur Spine J (2008) 1.16
Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus. J Immunol (2010) 1.16
Antithyroperoxidase and antithyroglobulin antibodies in a five-year follow-up survey of populations with different iodine intakes. J Clin Endocrinol Metab (2008) 1.16
Papillary microcarcinoma of the thyroid: clinical characteristics and BRAF(V600E) mutational status of 977 cases. Ann Surg Oncol (2013) 1.16
miR-29a and miR-142-3p downregulation and diagnostic implication in human acute myeloid leukemia. Mol Biol Rep (2011) 1.15
Phase I trial of "bi-shRNAi(furin)/GMCSF DNA/autologous tumor cell" vaccine (FANG) in advanced cancer. Mol Ther (2011) 1.15
Decreased circulating leptin level and its association with body and bone mass in girls with adolescent idiopathic scoliosis. Spine (Phila Pa 1976) (2007) 1.15
IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes. PLoS One (2011) 1.14
Metalloproteins containing cytochrome, iron-sulfur, or copper redox centers. Chem Rev (2014) 1.13
Complete genome sequence of a recombinant porcine epidemic diarrhea virus strain from eastern china. Genome Announc (2013) 1.12
Cardiovascular toxicity evaluation of silica nanoparticles in endothelial cells and zebrafish model. Biomaterials (2013) 1.11
11beta-hydroxysteroid dehydrogenase type 2 activity in hypothalamic paraventricular nucleus modulates sympathetic excitation. Hypertension (2006) 1.10
Cryptotanshinone suppressed inflammatory cytokines secretion in RAW264.7 macrophages through inhibition of the NF-κB and MAPK signaling pathways. Inflammation (2011) 1.10
Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats. Hypertension (2008) 1.09
An essential role for the Id1/PI3K/Akt/NFkB/survivin signalling pathway in promoting the proliferation of endothelial progenitor cells in vitro. Mol Cell Biochem (2011) 1.09
USP11 negatively regulates TNFalpha-induced NF-kappaB activation by targeting on IkappaBalpha. Cell Signal (2010) 1.09
Does Helicobacter pylori eradication really reduce the risk of gastric cancer at the population level? Gut (2012) 1.08
TAK1 Lys-158 but not Lys-209 is required for IL-1β-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-κB activation. Cell Signal (2010) 1.07
Toxic effect of silica nanoparticles on endothelial cells through DNA damage response via Chk1-dependent G2/M checkpoint. PLoS One (2013) 1.06
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors. Bioorg Med Chem Lett (2005) 1.06
Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis. Proc Natl Acad Sci U S A (2010) 1.06
Development of a colloidal gold-immunochromatography assay to detect immunoglobulin G antibodies to Treponema pallidum with TPN17 and TPN47. Diagn Microbiol Infect Dis (2010) 1.03
Nectin-like molecule 1 is a protein 4.1N associated protein and recruits protein 4.1N from cytoplasm to the plasma membrane. Biochim Biophys Acta (2005) 1.02
Gender-dependent expression of murine Irf5 gene: implications for sex bias in autoimmunity. J Mol Cell Biol (2010) 1.02
Reduced expression and novel splice variants of ING4 in human gastric adenocarcinoma. J Pathol (2009) 1.01
Dialkoxybenzene and dialkoxyallylbenzene feeding and oviposition deterrents against the cabbage looper, Trichoplusia ni: potential insect behavior control agents. J Agric Food Chem (2010) 1.01
TPO receptor agonist for chronic idiopathic thrombocytopenic purpura. Cochrane Database Syst Rev (2011) 1.00
Spatio-temporal variations of black carbon concentrations in the Megacity Beijing. Environ Pollut (2013) 1.00
ERK5 MAP kinase regulates neurogenin1 during cortical neurogenesis. PLoS One (2009) 0.99
Phase I trial of TGF-beta 2 antisense GM-CSF gene-modified autologous tumor cell (TAG) vaccine. Clin Cancer Res (2011) 0.99
Docetaxel weekly regimen in conjunction with RF hyperthermia for pretreated locally advanced non-small cell lung cancer: a preliminary study. BMC Cancer (2007) 0.99
Peritransplant ischemic injury is associated with up-regulation of stromal cell-derived factor-1. J Am Coll Cardiol (2005) 0.99
Comparative study of the cytokine/chemokine response in children with differing disease severity in enterovirus 71-induced hand, foot, and mouth disease. PLoS One (2013) 0.99
Surgery and survival outcomes of 30 patients with neurological deficit due to clear cell renal cell carcinoma spinal metastases. Eur Spine J (2015) 0.99
Silencing stromal interaction molecule 1 by RNA interference inhibits the proliferation and migration of endothelial progenitor cells. Biochem Biophys Res Commun (2010) 0.98
Sphingosine kinase 1 is a negative regulator of CD4+ Th1 cells. J Immunol (2005) 0.98
Growth inhibition induced by transforming growth factor-beta1 in human oral squamous cell carcinoma. Mol Biol Rep (2008) 0.97
Influence of iodine on the reference interval of TSH and the optimal interval of TSH: results of a follow-up study in areas with different iodine intakes. Clin Endocrinol (Oxf) (2008) 0.97
The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity. J Biol Chem (2013) 0.97
Adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia. Psychiatr Q (2006) 0.97
Analysis of elite variety tag SNPs reveals an important allele in upland rice. Nat Commun (2013) 0.97
The use of a tumor metastasis targeting peptide to deliver doxorubicin-containing liposomes to highly metastatic cancer. Biomaterials (2012) 0.97
Widespread disruption of genomic imprinting in adult interspecies mouse (Mus) hybrids. Genesis (2005) 0.96
Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors. Bioorg Med Chem Lett (2007) 0.96
Cell-autonomous inactivation of the reelin pathway impairs adult neurogenesis in the hippocampus. J Neurosci (2012) 0.96
The antitumor efficacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery. Biomaterials (2011) 0.96
Knockdown of transient receptor potential canonical-1 reduces the proliferation and migration of endothelial progenitor cells. Stem Cells Dev (2011) 0.96
MEKK3 is required for lysophosphatidic acid-induced NF-kappaB activation. Cell Signal (2009) 0.96
MDM2 SNP309 contributes to tumor susceptibility: a meta-analysis. J Genet Genomics (2011) 0.96
Males collectively defend their one-male units against bachelor males in a multi-level primate society. Am J Primatol (2013) 0.96
Outcomes of three anterior decompression and fusion techniques in the treatment of three-level cervical spondylosis. Eur Spine J (2011) 0.96
Surface functionalisation of diatoms with dopamine modified iron-oxide nanoparticles: toward magnetically guided drug microcarriers with biologically derived morphologies. Chem Commun (Camb) (2010) 0.96
Involvement of Annexin A2 in p53 induced apoptosis in lung cancer. Mol Cell Biochem (2007) 0.96
Radiographical predictors for postoperative sagittal imbalance in patients with thoracolumbar kyphosis secondary to ankylosing spondylitis after lumbar pedicle subtraction osteotomy. Spine (Phila Pa 1976) (2013) 0.95
Incremental value of dual-energy CT to coronary CT angiography for the detection of significant coronary stenosis: comparison with quantitative coronary angiography and single photon emission computed tomography. Int J Cardiovasc Imaging (2011) 0.95
Down-regulation of ING4 is associated with initiation and progression of lung cancer. Histopathology (2010) 0.95