MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1.

PubWeight™: 1.29‹?› | Rank: Top 10%

🔗 View Article (PMID 22198213)

Published in Carcinogenesis on December 22, 2011

Authors

Jianmin Wu1, Gang Wu, Lu Lv, Yong-Feng Ren, Xue-Jiao Zhang, Yong-Feng Xue, Guiling Li, Xincheng Lu, ZhongSheng Sun, Kai-Fu Tang

Author Affiliations

1: Institute of Genomic Medicine, Wenzhou Medical College, 268 Xueyuan Road, Wenzhou, Zhejiang 325000, People's Republic of China.

Articles citing this

miR-34: from bench to bedside. Oncotarget (2014) 1.59

The role of microRNAs in colorectal cancer. Cancer J (2012) 1.44

MicroRNA-34a: a potential therapeutic target in human cancer. Cell Death Dis (2014) 1.32

miR-34a-5p suppresses colorectal cancer metastasis and predicts recurrence in patients with stage II/III colorectal cancer. Oncogene (2014) 1.02

MicroRNA-638 inhibits cell proliferation, invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma. Oncotarget (2014) 0.98

The p53/microRNA connection in gastrointestinal cancer. Clin Exp Gastroenterol (2014) 0.90

MicroRNA overexpression increases cortical neuronal vulnerability to injury. Brain Res (2013) 0.90

Clinicopathological and prognostic significance of microRNA-107 in human non small cell lung cancer. Int J Clin Exp Pathol (2014) 0.89

MicroRNAs as Regulator of Signaling Networks in Metastatic Colon Cancer. Biomed Res Int (2015) 0.88

Long Noncoding RNAs as New Architects in Cancer Epigenetics, Prognostic Biomarkers, and Potential Therapeutic Targets. Biomed Res Int (2015) 0.88

MicroRNAs in the Regulation of MMPs and Metastasis. Cancers (Basel) (2014) 0.88

MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1. BMC Cancer (2013) 0.88

miR-34a inhibits migration and invasion of tongue squamous cell carcinoma via targeting MMP9 and MMP14. PLoS One (2014) 0.88

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression. BMC Cancer (2015) 0.86

microRNA-34a inhibits epithelial mesenchymal transition in human cholangiocarcinoma by targeting Smad4 through transforming growth factor-beta/Smad pathway. BMC Cancer (2015) 0.85

Role of microRNA-mediated MMP regulation in the treatment and diagnosis of malignant tumors. Cancer Biol Ther (2013) 0.85

Targeting MicroRNAs in Cancer Gene Therapy. Genes (Basel) (2017) 0.85

Interplay Between Metabolism and Oncogenic Process: Role of microRNAs. Transl Oncogenomics (2015) 0.84

MicroRNA-195-5p, a new regulator of Fra-1, suppresses the migration and invasion of prostate cancer cells. J Transl Med (2015) 0.83

Increased microRNA-34b and -34c predominantly expressed in stromal tissues is associated with poor prognosis in human colon cancer. PLoS One (2015) 0.82

The tumor-suppressive and potential therapeutic functions of miR-34a in epithelial carcinomas. Expert Opin Ther Targets (2015) 0.82

FRA-1 as a driver of tumour heterogeneity: a nexus between oncogenes and embryonic signalling pathways in cancer. Oncogene (2014) 0.82

The role of dicer in DNA damage repair. Int J Mol Sci (2012) 0.81

Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy. J Control Release (2016) 0.81

MiR-34a-5p promotes the multi-drug resistance of osteosarcoma by targeting the CD117 gene. Oncotarget (2016) 0.81

MiR-449a suppresses cell invasion by inhibiting MAP2K1 in non-small cell lung cancer. Am J Cancer Res (2015) 0.79

MiR-34a suppresses amphiregulin and tumor metastatic potential of head and neck squamous cell carcinoma (HNSCC). Oncotarget (2015) 0.76

The Fra-1-miR-134-SDS22 feedback loop amplifies ERK/JNK signaling and reduces chemosensitivity in ovarian cancer cells. Cell Death Dis (2016) 0.76

Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model. Theranostics (2017) 0.76

HPV16 early gene E5 specifically reduces miRNA-196a in cervical cancer cells. Sci Rep (2015) 0.76

Upregulation of miR-582-5p inhibits cell proliferation, cell cycle progression and invasion by targeting Rab27a in human colorectal carcinoma. Cancer Gene Ther (2015) 0.76

Copy number variation in hereditary non-polyposis colorectal cancer. Genes (Basel) (2013) 0.75

MiR-34a-5p promotes multi-chemoresistance of osteosarcoma through down-regulation of the DLL1 gene. Sci Rep (2017) 0.75

A functional SNP rs1892901 in FOSL1 is associated with gastric cancer in Chinese population. Sci Rep (2017) 0.75

Fra-1 regulation of Matrix Metallopeptidase-1 (MMP-1) in metastatic variants of MDA-MB-231 breast cancer cells. F1000Res (2013) 0.75

MicroRNA-34a expression levels in serum and intratumoral tissue can predict bone metastasis in patients with hepatocellular carcinoma. Oncotarget (2016) 0.75

Potential roles of microRNAs and ROS in colorectal cancer: diagnostic biomarkers and therapeutic targets. Oncotarget (2017) 0.75

The miR-34a-5p promotes the multi-chemoresistance of osteosarcoma via repression of the AGTR1 gene. BMC Cancer (2017) 0.75

MicroRNA-34a/EGFR axis plays pivotal roles in lung tumorigenesis. Oncogenesis (2017) 0.75

MicroRNA-34a suppresses colorectal cancer metastasis by regulating Notch signaling. Oncol Lett (2017) 0.75

Articles by these authors

(truncated to the top 100)

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature (2012) 9.89

SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis. Genes Dev (2004) 8.18

An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants. Proc Natl Acad Sci U S A (2006) 7.62

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med (2014) 5.37

Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes. J Med Chem (2008) 5.15

A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature (2012) 5.02

Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev (2007) 4.16

Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol (2006) 3.75

Nuclear processing and export of microRNAs in Arabidopsis. Proc Natl Acad Sci U S A (2005) 3.57

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet (2013) 3.51

The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet (2013) 3.43

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood (2011) 3.40

UV disinfection induces a VBNC state in Escherichia coli and Pseudomonas aeruginosa. Environ Sci Technol (2015) 3.26

Trans-acting siRNA-mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis. Development (2006) 2.93

A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the treatment of nasopharyngeal carcinoma. Radiother Oncol (2012) 2.54

Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nat Genet (2011) 2.32

Deproteinized bovine bone functionalized with the slow delivery of BMP-2 for the repair of critical-sized bone defects in sheep. Bone (2013) 2.09

Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses. J Natl Cancer Inst (2012) 2.09

The microRNA-regulated SBP-Box transcription factor SPL3 is a direct upstream activator of LEAFY, FRUITFULL, and APETALA1. Dev Cell (2009) 2.07

Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers. Mol Cell Biol (2005) 2.06

High-throughput screen for novel antimicrobials using a whole animal infection model. ACS Chem Biol (2009) 1.99

Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma. Hepatology (2010) 1.97

Correlation of mRNA expression and protein abundance affected by multiple sequence features related to translational efficiency in Desulfovibrio vulgaris: a quantitative analysis. Genetics (2006) 1.96

miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat Cell Biol (2013) 1.79

Meta-analysis of the prognostic value of circulating tumor cells in breast cancer. Clin Cancer Res (2012) 1.79

Correlation between mRNA and protein abundance in Desulfovibrio vulgaris: a multiple regression to identify sources of variations. Biochem Biophys Res Commun (2005) 1.73

An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. Cancer Cell (2012) 1.61

Cyclophilin 40 is required for microRNA activity in Arabidopsis. Proc Natl Acad Sci U S A (2009) 1.56

Integrative analysis of transcriptomic and proteomic data: challenges, solutions and applications. Crit Rev Biotechnol (2007) 1.56

N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic properties. J Pharmacol Exp Ther (2003) 1.56

Toward accurate high-throughput SNP genotyping in the presence of inherited copy number variation. BMC Genomics (2007) 1.54

Deletion of murine kininogen gene 1 (mKng1) causes loss of plasma kininogen and delays thrombosis. Blood (2007) 1.48

Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project. Blood (2012) 1.47

New covered mushroom-shaped metallic stent for managing anastomotic leak after esophagogastrostomy with a wide gastric tube. Ann Thorac Surg (2006) 1.47

Glycemic variability in gestational diabetes mellitus and its association with β cell function. Endocrine (2012) 1.46

Candidate pathway-based genome-wide association studies identify novel associations of genomic variants in the complement system associated with coronary artery disease. Circ Cardiovasc Genet (2014) 1.45

Primitive neuroectodermal tumor of the kidney with inferior vena cava tumor thrombus. J Natl Med Assoc (2009) 1.43

Antiproliferative, antiinvasive, and proapoptotic activity of folate receptor α-targeted liposomal doxorubicin in nonfunctional pituitary adenoma cells. Endocrinology (2013) 1.43

A novel approach: treatment of bronchial stump fistula with a plugged, bullet-shaped, angled stent. Ann Thorac Surg (2006) 1.42

Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy. Cancer Biother Radiopharm (2010) 1.33

Degradation of petroleum hydrocarbons (C6-C40) and crude oil by a novel Dietzia strain. Bioresour Technol (2011) 1.29

Effect of lipid-bound apoA-I cysteine mutants on lipopolysaccharide-induced endotoxemia in mice. J Lipid Res (2008) 1.28

Assessment of association of rs2200733 on chromosome 4q25 with atrial fibrillation and ischemic stroke in a Chinese Han population. Hum Genet (2009) 1.25

Eremophilane-type sesquiterpene derivatives from the roots of Ligularia lapathifolia. J Nat Prod (2007) 1.24

Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay. PLoS One (2009) 1.22

Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. J Pharmacol Exp Ther (2009) 1.20

Recql5 plays an important role in DNA replication and cell survival after camptothecin treatment. Mol Biol Cell (2008) 1.18

Correcting diastolic dysfunction by Ca2+ desensitizing troponin in a transgenic mouse model of restrictive cardiomyopathy. J Mol Cell Cardiol (2010) 1.17

Biomimetic coatings for bone tissue engineering of critical-sized defects. J R Soc Interface (2010) 1.17

Mutations in the GW-repeat protein SUO reveal a developmental function for microRNA-mediated translational repression in Arabidopsis. Proc Natl Acad Sci U S A (2011) 1.16

Evolution of the syntrophic interaction between Desulfovibrio vulgaris and Methanosarcina barkeri: Involvement of an ancient horizontal gene transfer. Biochem Biophys Res Commun (2006) 1.13

Heavy metal removal from water/wastewater by nanosized metal oxides: a review. J Hazard Mater (2011) 1.11

Selective binding of monovalent cations to the stacking G-quartet structure formed by guanosine 5'-monophosphate: a solid-state NMR study. J Am Chem Soc (2003) 1.11

Transcriptome analysis of leaf tissue of Raphanus sativus by RNA sequencing. PLoS One (2013) 1.11

Synthesis of isotopically labeled arachidonic acids to probe the reaction mechanism of prostaglandin H synthase. J Am Chem Soc (2002) 1.09

Significant association of SNP rs2106261 in the ZFHX3 gene with atrial fibrillation in a Chinese Han GeneID population. Hum Genet (2010) 1.09

Identification of NPPA variants associated with atrial fibrillation in a Chinese GeneID population. Clin Chim Acta (2010) 1.09

Integrated analysis of transcriptomic and proteomic data of Desulfovibrio vulgaris: zero-inflated Poisson regression models to predict abundance of undetected proteins. Bioinformatics (2006) 1.06

Analysis of myostatin gene structure, expression and function in zebrafish. J Exp Biol (2003) 1.06

Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma. PLoS One (2012) 1.06

Down-regulation of Dicer in hepatocellular carcinoma. Med Oncol (2010) 1.06

Amplification of the ch19p13.2 NACC1 locus in ovarian high-grade serous carcinoma. Mod Pathol (2011) 1.05

Identification of Tyr504 as an alternative tyrosyl radical site in human prostaglandin H synthase-2. Biochemistry (2004) 1.05

Three different oxygen-induced radical species in endothelial nitric-oxide synthase oxygenase domain under regulation by L-arginine and tetrahydrobiopterin. J Biol Chem (2004) 1.05

Performance of shear wave elastography for differentiation of benign and malignant solid breast masses. PLoS One (2013) 1.05

Phylogenetic analysis using complete signature information of whole genomes and clustered Neighbour-Joining method. Int J Bioinform Res Appl (2006) 1.05

Bacterial symbionts of the brown planthopper, Nilaparvata lugens (Homoptera: Delphacidae). Appl Environ Microbiol (2010) 1.03

Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population. Biochem Biophys Res Commun (2010) 1.03

Integrated cross-species transcriptional network analysis of metastatic susceptibility. Proc Natl Acad Sci U S A (2012) 1.03

The signaling and functions of heterodimeric bone morphogenetic proteins. Cytokine Growth Factor Rev (2012) 1.02

Expression of CDK5/p35 in resected patients with non-small cell lung cancer: relation to prognosis. Med Oncol (2010) 1.01

RNA interference in Nilaparvata lugens (Homoptera: Delphacidae) based on dsRNA ingestion. Pest Manag Sci (2011) 1.01

Optimal encoding rules for synthetic genes: the need for a community effort. Mol Syst Biol (2007) 1.01

MiR-200c increases the radiosensitivity of non-small-cell lung cancer cell line A549 by targeting VEGF-VEGFR2 pathway. PLoS One (2013) 1.00

DNA sequence analyses reveal abundant diversity, endemism and evidence for Asian origin of the porcini mushrooms. PLoS One (2012) 0.99

Changes of some anti-oxidative physiological indices under soil water deficits among 10 wheat (Triticum aestivum L.) genotypes at tillering stage. Colloids Surf B Biointerfaces (2006) 0.99

Direct NMR detection of alkali metal ions bound to G-quadruplex DNA. J Am Chem Soc (2008) 0.98

Genipin-cross-linked collagen/chitosan biomimetic scaffolds for articular cartilage tissue engineering applications. J Biomed Mater Res A (2010) 0.98

Rice dwarf phytoreovirus segment S6-encoded nonstructural protein has a cell-to-cell movement function. J Virol (2004) 0.98

Retrieval stent filter: treatment of Budd Chiari syndrome complicated with inferior vena cava thrombosis--initial clinical experience. Ann Thorac Surg (2007) 0.98

The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells. Mol Cell Biol (2012) 0.98

Radiation induced temporal lobe necrosis in patients with nasopharyngeal carcinoma: a review of new avenues in its management. Radiat Oncol (2011) 0.98

A rice β-1,3-glucanase gene Osg1 is required for callose degradation in pollen development. Planta (2010) 0.97

Tissue factor as a link between wounding and tissue repair. Diabetes (2005) 0.97

The IL-33-ST2L pathway is associated with coronary artery disease in a Chinese Han population. Am J Hum Genet (2013) 0.96

Determination of the structural environment of the tyrosyl radical in prostaglandin H2 synthase-1: a high frequency ENDOR/EPR study. J Am Chem Soc (2005) 0.96

Li-rich anti-perovskite Li3OCl films with enhanced ionic conductivity. Chem Commun (Camb) (2014) 0.96

Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data. Genome Biol (2012) 0.95

Regulation of CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism rs2043211 (p.C10X) with ischemic stroke. Stroke (2014) 0.95

Tamoxifen alleviates irradiation-induced brain injury by attenuating microglial inflammatory response in vitro and in vivo. Brain Res (2010) 0.95

Disodium guanosine 5'-monophosphate self-associates into nanoscale cylinders at pH 8: a combined diffusion NMR spectroscopy and dynamic light scattering study. J Am Chem Soc (2005) 0.94

Divergent polyamine metabolism in the Apicomplexa. Microbiology (2007) 0.94

Expression of FOXJ1 in hepatocellular carcinoma: correlation with patients' prognosis and tumor cell proliferation. Mol Carcinog (2012) 0.94

Role of different negative pressure values in the process of infected wounds treated by vacuum-assisted closure: an experimental study. Int Wound J (2012) 0.94

Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2. J Biol Chem (2002) 0.93

Graphene/graphene-tube nanocomposites templated from cage-containing metal-organic frameworks for oxygen reduction in Li-O₂ batteries. Adv Mater (2013) 0.93

In vitro generation of osteochondral differentiation of human marrow mesenchymal stem cells in novel collagen-hydroxyapatite layered scaffolds. Acta Biomater (2011) 0.92

Large-scale synthesis and self-assembly of monodisperse hexagon Cu2S nanoplates. Langmuir (2005) 0.92

Controlled attenuation parameter for the detection of steatosis severity in chronic liver disease: a meta-analysis of diagnostic accuracy. J Gastroenterol Hepatol (2014) 0.91