Published in Breast Cancer Res on January 19, 2012
Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity. Cell Rep (2014) 3.24
Microenvironmental regulation of epithelial-mesenchymal transitions in cancer. Cancer Res (2012) 2.00
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Res (2013) 1.92
Dietary chemopreventative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo. Cancer Prev Res (Phila) (2013) 1.59
ZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance. Cell Cycle (2015) 1.30
Pathways to breast cancer recurrence. ISRN Oncol (2013) 1.15
FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells. Oncotarget (2015) 1.09
Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer. Breast Cancer Res (2015) 1.04
Honokiol inhibits epithelial-mesenchymal transition in breast cancer cells by targeting signal transducer and activator of transcription 3/Zeb1/E-cadherin axis. Mol Oncol (2014) 0.96
Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells. Breast Cancer Res (2013) 0.96
Cisplatin induces differentiation of breast cancer cells. Front Oncol (2013) 0.92
Implications of Mesenchymal Cells in Cancer Stem Cell Populations: Relevance to EMT. Curr Pathobiol Rep (2014) 0.90
Beta-elemene blocks epithelial-mesenchymal transition in human breast cancer cell line MCF-7 through Smad3-mediated down-regulation of nuclear transcription factors. PLoS One (2013) 0.88
EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/β-catenin signaling. Oncotarget (2016) 0.86
NKX6.3 Is a Transcription Factor for Wnt/β-catenin and Rho-GTPase Signaling-Related Genes to Suppress Gastric Cancer Progression. EBioMedicine (2016) 0.85
Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo. PLoS One (2012) 0.85
Metalloproteinase-disintegrin ADAM12 is associated with a breast tumor-initiating cell phenotype. Breast Cancer Res Treat (2013) 0.84
The Role of Hypoxia and Cancer Stem Cells in Renal Cell Carcinoma Pathogenesis. Stem Cell Rev (2015) 0.84
Cell fusion between gastric epithelial cells and mesenchymal stem cells results in epithelial-to-mesenchymal transition and malignant transformation. BMC Cancer (2015) 0.83
Stem cell-like ALDH(bright) cellular states in EGFR-mutant non-small cell lung cancer: a novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin. Cell Cycle (2013) 0.83
Protein Kinase C-ε Promotes EMT in Breast Cancer. Breast Cancer (Auckl) (2014) 0.82
ROCK inhibition activates MCF-7 cells. PLoS One (2014) 0.82
CD44S-hyaluronan interactions protect cells resulting from EMT against anoikis. Matrix Biol (2015) 0.81
Systems analysis reveals a transcriptional reversal of the mesenchymal phenotype induced by SNAIL-inhibitor GN-25. BMC Syst Biol (2013) 0.81
Cancer Cell Colonisation in the Bone Microenvironment. Int J Mol Sci (2016) 0.81
Gastric tumor-initiating CD44(+) cells and epithelial-mesenchymal transition are inhibited by γ-secretase inhibitor DAPT. Oncol Lett (2015) 0.80
Inhibitors of Rho kinase (ROCK) signaling revert the malignant phenotype of breast cancer cells in 3D context. Oncotarget (2016) 0.80
Luteolin reduces the invasive potential of malignant melanoma cells by targeting β3 integrin and the epithelial-mesenchymal transition. Acta Pharmacol Sin (2012) 0.80
Strong correlation between N-cadherin and CD133 in breast cancer: role of both markers in metastatic events. J Cancer Res Clin Oncol (2014) 0.80
The emerging molecular machinery and therapeutic targets of metastasis. Trends Pharmacol Sci (2015) 0.80
Identification of genes involved in breast cancer and breast cancer stem cells. Breast Cancer (Dove Med Press) (2015) 0.80
Role of RANKL/RANK in primary and secondary breast cancer. World J Orthop (2013) 0.79
Inhibition of proliferation and migration of luminal and claudin-low breast cancer cells by PDGFR inhibitors. Cancer Cell Int (2014) 0.79
Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer. Oncotarget (2015) 0.79
Molecular deconstruction, detection, and computational prediction of microenvironment-modulated cellular responses to cancer therapeutics. Adv Drug Deliv Rev (2014) 0.79
Cancer stem cells: Role in tumor growth, recurrence, metastasis, and treatment resistance. Medicine (Baltimore) (2016) 0.78
The Roles of Epithelial-to-Mesenchymal Transition (EMT) and Mesenchymal-to-Epithelial Transition (MET) in Breast Cancer Bone Metastasis: Potential Targets for Prevention and Treatment. J Clin Med (2013) 0.78
LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene (2015) 0.78
Abcc10 status affects mammary tumour growth, metastasis, and docetaxel treatment response. Br J Cancer (2014) 0.78
Splicing factor ratio as an index of epithelial-mesenchymal transition and tumor aggressiveness in breast cancer. Oncotarget (2016) 0.77
Role of integrin-linked kinase in drug resistance of lung cancer. Onco Targets Ther (2015) 0.77
Autophagy Inhibition to Increase Radiosensitization in Breast Cancer. J Nucl Med Radiat Ther (2015) 0.77
Ionizing radiation promotes advanced malignant traits in nasopharyngeal carcinoma via activation of epithelial-mesenchymal transition and the cancer stem cell phenotype. Oncol Rep (2016) 0.77
Establishment of a novel human medulloblastoma cell line characterized by highly aggressive stem-like cells. Cytotechnology (2015) 0.77
Synergistic therapeutic effect of cisplatin and phosphatidylinositol 3-kinase (PI3K) inhibitors in cancer growth and metastasis of Brca1 mutant tumors. J Biol Chem (2014) 0.77
A 22q11.2 amplification in the region encoding microRNA-650 correlates with the epithelial to mesenchymal transition in breast cancer primary cultures of Mexican patients. Int J Oncol (2017) 0.76
Exploiting Gene Expression Kinetics in Conventional Radiotherapy, Hyperfractionation, and Hypofractionation for Targeted Therapy. Semin Radiat Oncol (2016) 0.76
Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation. Mol Cancer (2017) 0.76
ALX1 promotes migration and invasion of lung cancer cells through increasing snail expression. Int J Clin Exp Pathol (2015) 0.76
AKT-ions with a TWIST between EMT and MET. Oncotarget (2016) 0.76
NANOG signaling promotes metastatic capability of immunoedited tumor cells. Clin Exp Metastasis (2015) 0.76
The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair. Cancer Lett (2016) 0.76
Stem cell technology in breast cancer: current status and potential applications. Stem Cells Cloning (2016) 0.76
miR-494-3p is a novel tumor driver of lung carcinogenesis. Oncotarget (2016) 0.75
HOXA7 plays a critical role in metastasis of liver cancer associated with activation of Snail. Mol Cancer (2016) 0.75
IL1RN and KRT13 Expression in Bladder Cancer: Association with Pathologic Characteristics and Smoking Status. Adv Urol (2014) 0.75
Treating triple negative breast cancer cells with erlotinib plus a select antioxidant overcomes drug resistance by targeting cancer cell heterogeneity. Sci Rep (2017) 0.75
NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial-mesenchymal transition. Oncogene (2015) 0.75
Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer. Breast Cancer Res Treat (2017) 0.75
NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer. Cell Death Dis (2017) 0.75
Autophagy inhibition impairs the epithelial-mesenchymal transition and enhances cisplatin sensitivity in nasopharyngeal carcinoma. Oncol Lett (2017) 0.75
Epithelial-to-Pericyte Transition in Cancer. Cancers (Basel) (2017) 0.75
Lack of Breastfeeding History in Parous Women with Inflammatory Breast Cancer Predicts Poor Disease-Free Survival. J Cancer (2017) 0.75
New insights into the role of EMT in tumor immune escape. Mol Oncol (2017) 0.75
Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A (2003) 59.17
The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell (2008) 46.08
Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer (2002) 34.99
Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell (2003) 25.94
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell (2007) 22.89
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer (2003) 22.78
Cancer metastasis: building a framework. Cell (2006) 19.67
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer (2009) 18.53
Effect of screening and adjuvant therapy on mortality from breast cancer. N Engl J Med (2005) 16.70
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature (2005) 15.57
Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest (2003) 12.56
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst (2008) 11.93
The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol (2006) 11.16
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol (2007) 10.49
An overview of epithelio-mesenchymal transformation. Acta Anat (Basel) (1995) 9.18
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell (2009) 8.33
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A (2009) 7.95
Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression. J Cell Physiol (2007) 7.34
Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res (2008) 6.95
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A (2010) 6.15
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res (2009) 5.68
Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc Natl Acad Sci U S A (2007) 5.24
The role of epithelial-mesenchymal transition in cancer pathology. Pathology (2007) 5.16
Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science (2008) 4.71
Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res (2008) 3.41
Vimentin and epithelial-mesenchymal transition in human breast cancer--observations in vitro and in vivo. Cells Tissues Organs (2007) 3.12
Expression profiling of epithelial plasticity in tumor progression. Oncogene (2003) 2.67
Mesenchymal to epithelial transition in development and disease. Cells Tissues Organs (2007) 2.59
Survival of mammary stem cells in suspension culture: implications for stem cell biology and neoplasia. J Mammary Gland Biol Neoplasia (2005) 2.13
Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J Biol Chem (2004) 2.13
Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. J Mammary Gland Biol Neoplasia (2010) 2.00
Coordinating early kidney development: lessons from gene targeting. Nat Rev Genet (2002) 1.97
Cancer stem cells: are we missing the target? J Natl Cancer Inst (2004) 1.72
Patterns of resistance and incomplete response to docetaxel by gene expression profiling in breast cancer patients. J Clin Oncol (2005) 1.58
EMT tumorigenesis in the mouse mammary gland. Lab Invest (2007) 1.47
Regulation of stromal versican expression by breast cancer cells and importance to relapse-free survival in patients with node-negative primary breast cancer. Clin Cancer Res (2002) 1.36
Versican mediates mesenchymal-epithelial transition. Mol Biol Cell (2006) 1.34
Versican in nonsmall cell lung cancer: relation to hyaluronan, clinicopathologic factors, and prognosis. Hum Pathol (2005) 1.27
Expression of extracellular matrix components versican, chondroitin sulfate, tenascin, and hyaluronan, and their association with disease outcome in node-negative breast cancer. Clin Cancer Res (2004) 1.20
Prognostic significance of stromal versican expression in human endometrial cancer. Ann Oncol (2006) 0.99
High stromal versican expression predicts unfavourable outcome in oral squamous cell carcinoma. J Clin Pathol (2006) 0.88
Versican expression in pharyngeal squamous cell carcinoma: an immunohistochemical study. J Clin Pathol (2004) 0.87
Mouse models for human epithelial disease: novel insights and new horizons. Exp Physiol (2009) 0.78
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst (2008) 11.93
Role of transposable elements in heterochromatin and epigenetic control. Nature (2004) 10.51
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A (2009) 7.95
Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration. Nature (2010) 4.78
Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science (2008) 4.71
Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell (2009) 4.52
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature (2004) 4.41
Neoadjuvant trastuzumab induces apoptosis in primary breast cancers. J Clin Oncol (2005) 3.62
Loss of phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers. J Clin Oncol (2010) 2.93
ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proc Natl Acad Sci U S A (2007) 2.85
TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proc Natl Acad Sci U S A (2010) 2.72
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res (2013) 2.63
Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. Genes Dev (2007) 2.60
Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell (2003) 2.53
Gastroesophageal reflux might cause esophagitis through a cytokine-mediated mechanism rather than caustic acid injury. Gastroenterology (2009) 2.05
Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. J Mammary Gland Biol Neoplasia (2010) 2.00
Microenvironmental regulation of epithelial-mesenchymal transitions in cancer. Cancer Res (2012) 2.00
Multicenter phase II study of neoadjuvant lapatinib and trastuzumab with hormonal therapy and without chemotherapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer: TBCRC 006. J Clin Oncol (2013) 1.81
Molecular heterogeneity of inflammatory breast cancer: a hyperproliferative phenotype. Clin Cancer Res (2006) 1.67
High-throughput selection of effective RNAi probes for gene silencing. Genome Res (2003) 1.65
Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. Cancer Res (2012) 1.57
Inducible, reversible, and stable RNA interference in mammalian cells. Proc Natl Acad Sci U S A (2004) 1.55
Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression. Biochim Biophys Acta (2009) 1.54
Id1 restrains p21 expression to control endothelial progenitor cell formation. PLoS One (2007) 1.52
Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Sci Transl Med (2010) 1.43
Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (cytoxan) (AC) response and resistance. Breast Cancer Res Treat (2006) 1.32
Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer. Clin Cancer Res (2013) 1.30
ABT-869, a multitargeted receptor tyrosine kinase inhibitor: inhibition of FLT3 phosphorylation and signaling in acute myeloid leukemia. Blood (2007) 1.26
Patient-derived breast tumor xenografts facilitating personalized cancer therapy. Breast Cancer Res (2013) 1.23
Nitric oxide activates diverse signaling pathways to regulate gene expression. J Biol Chem (2003) 1.22
A comparison of coronal plane axial femoral relationships in Asian patients with varus osteoarthritic knees and healthy knees. J Arthroplasty (2008) 1.21
MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells. Cancer Res (2012) 1.21
High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy. Clin Cancer Res (2010) 1.20
Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors. Clin Cancer Res (2013) 1.20
Neoadjuvant trastuzumab and docetaxel in breast cancer: preliminary results. Clin Breast Cancer (2003) 1.18
Trastuzumab-resistant cells rely on a HER2-PI3K-FoxO-survivin axis and are sensitive to PI3K inhibitors. Cancer Res (2012) 1.17
Suppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migration. Cancer Cell (2013) 1.14
Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model. PLoS One (2012) 1.14
Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas. Proc Natl Acad Sci U S A (2008) 1.13
Acute liver failure caused by 'fat burners' and dietary supplements: a case report and literature review. Can J Gastroenterol (2011) 1.08
Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization. PLoS One (2007) 1.08
Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency. Breast Cancer Res (2013) 1.06
The role of bone-marrow-derived cells in tumor growth, metastasis initiation and progression. Trends Mol Med (2009) 1.05
Discovery of novel human breast cancer microRNAs from deep sequencing data by analysis of pri-microRNA secondary structures. PLoS One (2011) 1.05
Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density. Breast Cancer Res Treat (2009) 1.04
Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer. Breast Cancer Res (2015) 1.04
Use of locking compression plates for long bone nonunions without removing existing intramedullary nail: review of literature and our experience. J Trauma (2008) 1.03
Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth. Cancer Res (2010) 1.00
Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth. J Natl Cancer Inst (2010) 0.98
Gender-specific high-flexion knee prosthesis in Indian women: a prospective randomised study. J Orthop Surg (Hong Kong) (2012) 0.97
A gene transcription signature of obesity in breast cancer. Breast Cancer Res Treat (2011) 0.96
Hoffa fracture with ipsilateral patellar dislocation resulting from household trauma. Can J Surg (2009) 0.95
Prognostic markers for invasive micropapillary carcinoma of the breast: a population-based analysis. Clin Breast Cancer (2013) 0.95
Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1. Cancer Discov (2013) 0.94
Delivery of gene silencing agents for breast cancer therapy. Breast Cancer Res (2013) 0.94
Modeling of nanotherapeutics delivery based on tumor perfusion. New J Phys (2013) 0.94
Stem cells: Metabolism regulates differentiation. Nat Chem Biol (2010) 0.90
Distinct sites on G protein beta gamma subunits regulate different effector functions. J Biol Chem (2002) 0.88
Total hip arthroplasty following failed fixation of proximal hip fractures. Indian J Orthop (2008) 0.88
Incremental increase in VEGFR1⁺ hematopoietic progenitor cells and VEGFR2⁺ endothelial progenitor cells predicts relapse and lack of tumor response in breast cancer patients. Breast Cancer Res Treat (2011) 0.86
Minimally invasive plate osteosynthesis using a locking compression plate for diaphyseal humeral fractures. J Orthop Surg (Hong Kong) (2012) 0.85
Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1. Stem Cells (2014) 0.84
Stat5: from breast development to cancer prognosis, prediction, and progression. J Clin Oncol (2011) 0.84
Clinical response to neoadjuvant docetaxel predicts improved outcome in patients with large locally advanced breast cancers. Breast Cancer Res Treat (2005) 0.83
Prophylactic use of antibiotic-loaded bone cement in primary total knee arthroplasty: Justified or not? Indian J Orthop (2009) 0.81
Tumor microenvironment regulates epithelial-mesenchymal transitions in metastasis. Expert Rev Anticancer Ther (2012) 0.78
Genomic approaches to understanding and treating breast cancer. Breast Dis (2004) 0.78
Apoptosis induction by the core biopsy procedure. J Clin Oncol (2005) 0.77
Development of acneiform rash does not predict response to lapatinib treatment in patients with breast cancer. Pharmacotherapy (2013) 0.76
Insulin resistance and clustering of atherogenic risk factors in women belonging to low socio-economic strata in urban slums of North India. Diabetes Res Clin Pract (2002) 0.76
Enhanced mammary progesterone receptor-A isoform activity in the promotion of mammary tumor progression by dietary soy in rats. Nutr Cancer (2010) 0.75
Cancer stem cells: A nuanced perspective. Medicine (Baltimore) (2016) 0.75
Comparative study of the results of compound tibial shaft fractures treated by Ilizarov ring fixators and limb reconstruction system fixators. Chin J Traumatol (2015) 0.75