Published in FASEB J on July 14, 2010
Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions. Curr Biol (2012) 1.05
A novel actin binding site of myosin required for effective muscle contraction. Nat Struct Mol Biol (2012) 1.00
Comparative kinetic and functional characterization of the motor domains of human nonmuscle myosin-2C isoforms. J Biol Chem (2011) 0.92
Switch II mutants reveal coupling between the nucleotide- and actin-binding regions in myosin V. Biophys J (2012) 0.91
Magnesium impacts myosin V motor activity by altering key conformational changes in the mechanochemical cycle. Biochemistry (2013) 0.82
Magnesium modulates actin binding and ADP release in myosin motors. J Biol Chem (2014) 0.77
Global fit analysis of myosin-5b motility reveals thermodynamics of Mg2+-sensitive acto-myosin-ADP states. PLoS One (2013) 0.77
A subdomain interaction at the base of the lever allosterically tunes the mechanochemical mechanism of myosin 5a. PLoS One (2013) 0.75
Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localization. Science (2003) 20.21
The GTPase superfamily: conserved structure and molecular mechanism. Nature (1991) 19.64
Myosin-V is a processive actin-based motor. Nature (1999) 7.13
Structural mechanism of muscle contraction. Annu Rev Biochem (1999) 5.56
Brain myosin-V is a two-headed unconventional myosin with motor activity. Cell (1993) 5.24
Direct, real-time measurement of rapid inorganic phosphate release using a novel fluorescent probe and its application to actomyosin subfragment 1 ATPase. Biochemistry (1994) 4.97
The kinetic mechanism of myosin V. Proc Natl Acad Sci U S A (1999) 4.56
Myosin VI is a processive motor with a large step size. Proc Natl Acad Sci U S A (2001) 3.95
Load-dependent kinetics of myosin-V can explain its high processivity. Nat Cell Biol (2005) 3.69
A structural state of the myosin V motor without bound nucleotide. Nature (2003) 3.63
The molecular mechanism of muscle contraction. Adv Protein Chem (2005) 3.30
Three myosin V structures delineate essential features of chemo-mechanical transduction. EMBO J (2004) 3.21
Kinetic mechanism and regulation of myosin VI. J Biol Chem (2001) 2.93
Relating biochemistry and function in the myosin superfamily. Curr Opin Cell Biol (2004) 2.31
Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure (2007) 2.25
Kinetics of nucleoside triphosphate cleavage and phosphate release steps by associated rabbit skeletal actomyosin, measured using a novel fluorescent probe for phosphate. Biochemistry (1997) 2.23
Neck length and processivity of myosin V. J Biol Chem (2003) 2.23
Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance. J Biol Chem (2003) 2.19
Switches, latches, and amplifiers: common themes of G proteins and molecular motors. J Cell Biol (1996) 2.02
The Database of Macromolecular Motions: new features added at the decade mark. Nucleic Acids Res (2006) 1.89
Walking with myosin V. Curr Opin Cell Biol (2005) 1.79
Resolution of conformational states of Dictyostelium myosin II motor domain using tryptophan (W501) mutants: implications for the open-closed transition identified by crystallography. Biochemistry (2000) 1.73
The yeast class V myosins, Myo2p and Myo4p, are nonprocessive actin-based motors. J Cell Biol (2001) 1.72
Kinetic resolution of a conformational transition and the ATP hydrolysis step using relaxation methods with a Dictyostelium myosin II mutant containing a single tryptophan residue. Biochemistry (2001) 1.71
Step-size is determined by neck length in myosin V. Biochemistry (2005) 1.63
Magnesium, ADP, and actin binding linkage of myosin V: evidence for multiple myosin V-ADP and actomyosin V-ADP states. Biochemistry (2005) 1.53
The motor mechanism of myosin V: insights for muscle contraction. Philos Trans R Soc Lond B Biol Sci (2004) 1.53
A myosin II mutation uncouples ATPase activity from motility and shortens step size. Nat Cell Biol (2001) 1.52
Nanometer localization of single green fluorescent proteins: evidence that myosin V walks hand-over-hand via telemark configuration. Biophys J (2004) 1.50
Kinetic characterization of the weak binding states of myosin V. Biochemistry (2002) 1.46
Actin and light chain isoform dependence of myosin V kinetics. Biochemistry (2000) 1.45
The case for a common ancestor: kinesin and myosin motor proteins and G proteins. J Muscle Res Cell Motil (1998) 1.44
Magnesium regulates ADP dissociation from myosin V. J Biol Chem (2004) 1.42
The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II. J Biol Chem (2008) 1.37
Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family. J Biol Chem (2005) 1.32
Functional role of loop 2 in myosin V. Biochemistry (2004) 1.29
Structural evidence for a common intermediate in small G protein-GEF reactions. Mol Cell (2007) 1.20
Human myosin Vc is a low duty ratio, nonprocessive molecular motor. J Biol Chem (2008) 1.11
Mutational analysis of the switch II loop of Dictyostelium myosin II. J Biol Chem (1998) 1.10
A fluorescence temperature-jump study of conformational transitions in myosin subfragment 1. Biochem J (2001) 1.05
The dynamics of the relay loop tryptophan residue in the Dictyostelium myosin motor domain and the origin of spectroscopic signals. J Biol Chem (2001) 1.05
Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis. J Cell Sci (2006) 1.03
Switch 1 mutation S217A converts myosin V into a low duty ratio motor. J Biol Chem (2008) 1.01
Myosin Va is required for normal photoreceptor synaptic activity. J Cell Sci (2004) 1.01
Changes in Mg2+ ion concentration and heavy chain phosphorylation regulate the motor activity of a class I myosin. J Biol Chem (2004) 0.99
Dimerized Drosophila myosin VIIa: a processive motor. Proc Natl Acad Sci U S A (2006) 0.99
Myosin V and the endoplasmic reticulum: the connection grows. J Cell Biol (2003) 0.90
Mechanism, regulation, and functional properties of Dictyostelium myosin-1B. J Biol Chem (2007) 0.89
Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (2003) 12.41
Mechanism of blebbistatin inhibition of myosin II. J Biol Chem (2004) 5.45
The gated gait of the processive molecular motor, myosin V. Nat Cell Biol (2002) 5.34
Identification of an organelle receptor for myosin-Va. Nat Cell Biol (2002) 4.06
Load-dependent kinetics of myosin-V can explain its high processivity. Nat Cell Biol (2005) 3.69
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia. Nat Cell Biol (2005) 3.15
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem (2003) 2.98
Specificity of blebbistatin, an inhibitor of myosin II. J Muscle Res Cell Motil (2004) 2.96
Blebbistatin, a myosin II inhibitor, is photoinactivated by blue light. Biochemistry (2005) 2.29
Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure (2007) 2.25
Neck length and processivity of myosin V. J Biol Chem (2003) 2.23
Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells. J Natl Cancer Inst (2005) 2.23
Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance. J Biol Chem (2003) 2.19
The prepower stroke conformation of myosin V. J Cell Biol (2002) 2.12
The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head. J Biol Chem (2005) 2.11
The cargo-binding domain regulates structure and activity of myosin 5. Nature (2006) 2.03
Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform. J Biol Chem (2003) 2.03
Load-dependent mechanism of nonmuscle myosin 2. Proc Natl Acad Sci U S A (2007) 1.97
Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing. Cell (2010) 1.94
Walking to work: roles for class V myosins as cargo transporters. Nat Rev Mol Cell Biol (2011) 1.93
Regulated conformation of myosin V. J Biol Chem (2003) 1.90
Rab27a is an essential component of melanosome receptor for myosin Va. Mol Biol Cell (2002) 1.89
The clinical risk of vertebral artery injury from cervical pedicle screws inserted in degenerative vertebrae. Spine (Phila Pa 1976) (2005) 1.88
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. J Biol Chem (2005) 1.86
Application of the PM6 semi-empirical method to modeling proteins enhances docking accuracy of AutoDock. J Cheminform (2009) 1.85
Myosin cleft movement and its coupling to actomyosin dissociation. Nat Struct Biol (2003) 1.80
Step-size is determined by neck length in myosin V. Biochemistry (2005) 1.63
Direct observation of the mechanochemical coupling in myosin Va during processive movement. Nature (2008) 1.51
Nanometer localization of single green fluorescent proteins: evidence that myosin V walks hand-over-hand via telemark configuration. Biophys J (2004) 1.50
Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function. J Biol Chem (2002) 1.44
Polarized actin bundles formed by human fascin-1: their sliding and disassembly on myosin II and myosin V in vitro. J Neurochem (2003) 1.39
Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family. J Biol Chem (2005) 1.32
A FERM domain autoregulates Drosophila myosin 7a activity. Proc Natl Acad Sci U S A (2009) 1.29
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proc Natl Acad Sci U S A (2012) 1.29
The SAH domain extends the functional length of the myosin lever. Proc Natl Acad Sci U S A (2009) 1.29
Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power stroke. J Biol Chem (2007) 1.28
Mutation spectrum of MYO7A and evaluation of a novel nonsyndromic deafness DFNB2 allele with residual function. Hum Mutat (2008) 1.27
Atlantoaxial transarticular screw fixation for a high-riding vertebral artery. Spine (Phila Pa 1976) (2003) 1.27
Characterization of three full-length human nonmuscle myosin II paralogs. J Biol Chem (2013) 1.23
Homology modeling of breast cancer resistance protein (ABCG2). J Struct Biol (2007) 1.22
Predicting P-glycoprotein-mediated drug transport based on support vector machine and three-dimensional crystal structure of P-glycoprotein. PLoS One (2011) 1.17
Myo4p is a monomeric myosin with motility uniquely adapted to transport mRNA. J Cell Biol (2007) 1.17
Reversible movement of switch 1 loop of myosin determines actin interaction. EMBO J (2007) 1.17
Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme. J Biol Chem (2007) 1.14
Mechanism of action of myosin X, a membrane-associated molecular motor. J Biol Chem (2005) 1.14
Detection of a dural defect by cinematic magnetic resonance imaging and its selective closure as a treatment for a spinal extradural arachnoid cyst. Spine (Phila Pa 1976) (2004) 1.14
Subaxial subluxation after atlantoaxial transarticular screw fixation in rheumatoid patients. Eur Spine J (2009) 1.13
Human myosin Vc is a low duty ratio, nonprocessive molecular motor. J Biol Chem (2008) 1.11
Myosin regulatory light chain (RLC) phosphorylation change as a modulator of cardiac muscle contraction in disease. J Biol Chem (2013) 1.10
Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane. Mol Biol Cell (2010) 1.09
Processive translocation mechanism of the human Bloom's syndrome helicase along single-stranded DNA. Nucleic Acids Res (2010) 1.08
In vitro reconstitution of a transport complex containing Rab27a, melanophilin and myosin Va. FEBS Lett (2006) 1.08
Emerging complex pathways of the actomyosin powerstroke. Trends Biochem Sci (2010) 1.07
Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue. Biochemistry (2006) 1.06
Gamma-aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism. Cancer Res (2003) 1.06
Influence of lever structure on myosin 5a walking. Proc Natl Acad Sci U S A (2010) 1.05
Delayed postoperative spinal epidural hematoma causing tetraplegia. Case report. J Neurosurg Spine (2006) 1.04
Kinetic characterization of nonmuscle myosin IIb at the single molecule level. J Biol Chem (2012) 1.02
Evaluation of drug-human serum albumin binding interactions with support vector machine aided online automated docking. Bioinformatics (2011) 1.02
Switch 1 mutation S217A converts myosin V into a low duty ratio motor. J Biol Chem (2008) 1.01
Selective perturbation of the myosin recovery stroke by point mutations at the base of the lever arm affects ATP hydrolysis and phosphate release. J Biol Chem (2007) 1.01
Interactions of granisetron with an agonist-free 5-HT3A receptor model. Biochemistry (2006) 1.00
Probing the binding of the flavonoid, quercetin to human serum albumin by circular dichroism, electronic absorption spectroscopy and molecular modelling methods. Biochem Pharmacol (2003) 0.99
Dimerized Drosophila myosin VIIa: a processive motor. Proc Natl Acad Sci U S A (2006) 0.99
Two-headed binding of the unphosphorylated nonmuscle heavy meromyosin.ADP complex to actin. Biochemistry (2004) 0.98
A safe screw trajectory for atlantoaxial transarticular fixation achieved using an aiming device. Spine (Phila Pa 1976) (2005) 0.98
Association of cytochrome P450 enzymes is a determining factor in their catalytic activity. J Comput Aided Mol Des (2005) 0.98
Functional and structural characterization of a protein based on analysis of its hydrogen bonding network by hydrogen bonding plot. Arch Biochem Biophys (2007) 0.98
An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation. J Biol Chem (2009) 0.97
Binding interactions of antagonists with 5-hydroxytryptamine3A receptor models. J Recept Signal Transduct Res (2003) 0.96
S-1 monotherapy as second-line treatment for advanced pancreatic cancer after gemcitabine failure. Jpn J Clin Oncol (2010) 0.96
FTY720 induced Bcl-associated and Fas-independent apoptosis in human renal cancer cells in vitro and significantly reduced in vivo tumor growth in mouse xenograft. Anticancer Res (2007) 0.95
Weekly paclitaxel for heavily treated advanced or recurrent gastric cancer refractory to fluorouracil, irinotecan, and cisplatin. Gastric Cancer (2010) 0.95
Loss of actomyosin regulation in distal arthrogryposis myopathy due to mutant myosin binding protein-C slow. FASEB J (2013) 0.94
Myosin VIIB from Drosophila is a high duty ratio motor. J Biol Chem (2005) 0.92
Cervical disc herniation causing localized ipsilateral popliteal pain. J Orthop Sci (2002) 0.92
Loop 2 of limulus myosin III is phosphorylated by protein kinase A and autophosphorylation. Biochemistry (2007) 0.92
Use of an aiming device in posterior atlantoaxial transarticular screw fixation. Technical note. J Neurosurg (2002) 0.91
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke. Proc Natl Acad Sci U S A (2010) 0.91
Light-triggered myosin activation for probing dynamic cellular processes. Angew Chem Int Ed Engl (2011) 0.91
Mammalian myosin-18A, a highly divergent myosin. J Biol Chem (2013) 0.91